• Title/Summary/Keyword: 약물 경제학

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Shaping of Hormone drug Knowledge and drug market: Athletes use and consumption of synthetic hormones (호르몬 약물 지식과 시장의 형성: 운동선수들의 합성 호르몬 사용과 소비)

  • Han, Gwnag Hee;Kim, Byung Soo
    • Journal of Science and Technology Studies
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    • v.14 no.1
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    • pp.87-116
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    • 2014
  • This article focuses on synthetic hormone consumption that illegal act of heterogeneous forms of pharmaceuticalization. Athletes are not unfamiliar with the use of synthetic hormones that contain anabolic steroids. Synthetic hormones are used to increase muscle mass and strength. This drug use practice cannot simply be viewed as illegal. Athletes accumulate knowledge on these hormones that conflicts with the knowledge proffered by physicians and they consume drugs responsibly. Physicians' knowledge of these hormones is limited to their use in the treatment of abnormalities. Athletes, however, are expanding the role of these hormones to include their potential for enhancement. Thereby, a new value is assigned to synthetic hormones, and an informal market is formed. Previous studies in the fields of biopolitics and biomedicalization have mainly focused on the formal connection between biomedical science and the institutional network. This article, therefore, analyzes the informal and the various aspects of biomedicalization.

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A Study on the External Treatment of Dysmenorrhea using the Method of applying Herb-medicine at the acupoints (월경통(月經痛)의 약물혈위첩부치료법(藥物穴位貼敷治療法)에 대한 고찰(考察))

  • Lim, Eun-Mee
    • The Journal of Korean Medicine
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    • v.16 no.2 s.30
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    • pp.134-148
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    • 1995
  • Dysmenorrhea is probably the most common of all Gynecologic disorders. In the oriental medicine the etiology of Dysmenorrhea is very various, but its mechanism is just that the block of the flow makes the pain. So its treatment is removing the pain by promoting menstrual flow, promoting the flow of qi and by warming channel and activating blood flow. In the various treatments of dysmenorrhea, the method of applying drug at the acupoints which could be combined with feeding herb-medicine by oral was studied. The results obtained here were as follows; 1. In the treatments of dysmenorrhea, the method of applying drug at the acupoints was mainly applied to the type dued to stagnancy of qi and blood stasis, menorrhalgia dued to to cold and dampness, and primary dysmenorrhea. 2. The acupoint used in this treatment was Shin-gwol$(CV_8)$, the umbilicus. 3. The drugs used in this treatment were almost same as oral herb-medicine mainly to activate the blood flow and remove the blood stasis and to promote the flow of qi by warming the channel and remove the pain. 4. The duration of the treatment is, from 3 days before menstration till its period or a few days after it., usually concentrated on fore-postmenstration. 5. The effect of this treatment was reported as excellent. It is more effective to the type of stagnancy of qi and blood stasis, cold and dampness than dued to deficiency of both qi and blood, and dued to the impaired liver-kidney essence. 6. The method of applying drug at the acupoint was as an external treatment, easy, economical, and had no pain and side effect. 7. In the treatments of dysmenorrhea, the method of applying drug at the acupoint could be used as emergency treatment and symptomatic treatment in fore-postmenstration.

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Factors related to the Experience of Violence Damage among Multi-cultural and General Adolescents in Korea: Focusing on health risk behavior (한국 다문화 청소년과 일반 청소년의 폭력피해경험 관련요인 : 건강위험행위를 중심으로)

  • Paek, Kyung-Shin
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.2
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    • pp.193-204
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    • 2022
  • This study was to identify factors related to the experience of violence damage, focusing on health risk behavior of multi-cultural and general adolescents in Korea. Data from the 15th online survey of youth health behavior (2019) was used to analyze 35,574 adolescents. The data were analyzed using complex sample analysis by using SPSS/Win 22.0. The multi-cultural adolescents had significantly higher experience of smoking and habitual drug use and violence damage than those ordinary adolescents. In both multi-cultural and general adolescents, the more they did not live with their family, the more they had smoking experience and habitual drug use experience, the higher they experienced violence. The experience of violence victimization of general youth was significantly related to gender, school, economic status, and drinking experience. To prevent the violence victimization of adolescents, social support for adolescents who do not live with their families is required, and careful attention is needed to adolescents who have smoking and drug use experience. In addition, since multi-cultural youth are more vulnerable to health risk behaviors and violence damage than general youth, educational programs are needed to induce multi-cultural youth to practice correct health behaviors and prevent experiences of violence.

Effect of gender on the pharmacokinetics and metabolite formation of sulfamethazine in the rabbit (토끼의 성차가 sulfamethazine의 약동학 및 대사산물 생성에 미치는 영향)

  • Yun, Hyo-in;Park, Il-hyun
    • Korean Journal of Veterinary Research
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    • v.32 no.1
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    • pp.35-39
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    • 1992
  • SMZ is one of the most widely used antibacterial agents in veterinary medicine. It is also used as a growth promotant in many species of domestic animals There are marked species differences in its metabolism and pharmacokinetics. However, its pharmacokinetic and metabolism in rabbits. which are ragarded not only as good laboratorty animals hut also as good economical animals in its own, are lacking. Sex-differences in drug metabolism are well recognized in wide range of animal species including rats. Males are known to he more active than females. It is also know that there are Significant differences in the direction of metabolic pathways. But recently, female goats are reported to be more active in the metabolie capacity of SMZ than the other sex by Dutch researchers at Utrecht. Therefore, it is not easy to make general conclusicn of having higher SMZ metal-die capacity in the male compared to the opposite sex in every animal species. In this regard, the study on metabolic pattern of SMZ in rabbits, which are regarded as hervivorous, is of interest because the dietary habbits of rabbit are comparable to thai of goal, NEW Zealand White rabbits of each sex were given SMZ(35mg/kg) as a bolus injection into the marginalean, vein in order to study its pharmacokinetic profiles(using plasma) anc metabolic pattem(24h urine) as specified in the methods anc materials. 1. In the rabbit, the major metabolic pathway of SMZ was the acetylation(the formation of $N_4AcSMZ$). There were hydroxylation pathways(50HSMZ, $6CH_2OHSMZ$) as well, in the metabolism of SMZ in the rabbit, but minor pathways. 2. No sex differences in the metabolic direction of SMZ and its metabolites formation were found from the urinary excreted metabolites of SMZ out of 24h collected urine. 3. The concentration-time curves of SMZ(35mg/kg, iv) in the plasma compartment were fitted to a one-compartment open model when using a computer program(NONLIN). There was also no difference in the pharmacokinetic pattem of SMZ between two sexes. 4. The emergence of $N_4AcSMZ$ metabolized from SMZ was very fast in the plasma of the rabbit The elimination of $N_4AcSMZ$ was prolonged as compared to that of the parent drug Vie found no sex difference in the elimination pattern of $N_4AcSMZ$ in the rabbit.

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Adolescent Suicides in Korea: Predictors and Interventions

  • Choi, Jin-Young;Davis, Mary Ann
    • The Journal of Korean Society for School & Community Health Education
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    • v.10 no.1
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    • pp.61-86
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    • 2009
  • 본 연구는 영문으로 발표된 문헌고찰을 통해 한국의 청소년 자살행동의 예측요인을 종합적으로 이해하고 이과 관련된 정책과 중재프로그램의 동향을 파악하는데 그 목적을 두었다. 이 연구의 목적은 나아가 한국 청소년 자살을 감소시키고 억제하는데 필요한 효과적인 중재방안의 개발에 근거자료로 활용될 수 있다. 본 연구는 주제어 검색을 통해 4대 사회과학 검색엔진을 활용하여 문헌검색을 하였고 Citation Pearl Growing 기법을 적용하여 영문으로 발표된 학술지 게재 논문을 선별하였는데 추가적으로 국회도서관 전자 데이터베이스를 이용하여 최근 청소년 자살에 관한 대표적인 2개의 보고서를 찾아 고찰하였다. 본 문헌고찰은 청소년 자살예방 중재 프로그램 뿐만 아니라 청소년 자살행동에 영향을 주는 요인을 거시적, 미시적 차원으로 논하였다. 청소년 자살행동에 기여하는 거시적 또는 사회적 요인은 국가 경제수준, 대학입시에 대한 학업성취도 스트레스, 그리고 매체 및 인터넷 문화였다. 개인적 또는 미시적 위험요인은 6개의 영역으로 나누어 설명되었다. 일반적 특성, 가족 특성, 학교 환경, 약물 사용, 정신적 장애, 성적 정체성이었다 이 6개 영역의 위험요인들이 서로 조합되면서 청소년에게 자살 의도나 시도가 일어나도록 하는 경향이 높았으며 이중 청소년 자살 예방에 우선적인 3대 요소는 자아정체성 확립, 정신건강 중재서비스의 제공, 거시적 예방 정책의 구조화로 분석되었다. 종합적으로 학교는 정규학교교육과정과 학생 검사를 통해서 일반적인 정신건강교육을 실시하고 위험학생을 선별 하는데 핵심적인 장이다. 따라서 학교를 경유한 위험학생 선별사업과 이에 따른 교육 및 중재 프로그램의 지원이 활성화되는 것이 필요하다.

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A Study on Understanding of Middle-East Terrorism : Focusing on Islamic Fundamentalism (이슬람 원리주의를 통해 본 중동지역테러리즘의 이해)

  • Park, Gi-Beom;Kang, Min-Wan;Jun, Yong-Tae
    • Korean Security Journal
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    • no.12
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    • pp.149-175
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    • 2006
  • The purpose of this study is to understand and analyze the character of Islamic fundamentalism and Middle-Ease Terrorism. The aim of Islamic fundamentalism is reconstruction of Ummah(Muslim Unity), thee early society of Muhammad's age. Islamic movement insist to restore the spirit of Islam and purify the society of Islam from the United State and Western world. Now, Islamic fundamentalism movement as a new ideology, appeals to muslim in the world. The concept of modern national state from the Western countries do not accord with the traditional Islamic principles of reign and a spirit of nationalism. On the other hand, Islamic movement have no legitimacy in the system of modern state which govern the Arab world, regardless of the form of government. For this reasons, Islamic fundamentalist have an insecure position and their political activities. It is yet far from their purpose, to reconstruct the muslim unity, to realize the Islamic political principle close to their practical methods. Yet Islamic fundamental movement have not overcome the system of secular state. The Middle East terrorism supported by government might be eradicated by America's anti-terrorism policy. However, it will be serious and spread all over the world that the terrorist attack against the U. S. and western countries is acted by militant warriors of Islamic fundamentalism, uniting Arab and Islamic people's emotions against America and western countries. There are some reasons that we need to focus on the Arab and Islamic fundamentalism. We need to get out of misunderstanding and discrimination about Islamic religion and culture from America's and Western' standard Which are only their new world order. The discrimination of America and western nations against muslim could make other ideologies, opposite to the world peace. There are a lot of foreign workers from Islam countries in Korea. We need to give consideration and attention to them for the our globalization and world peace. It is time to consider what to do for the nation's profit(economical, political, strategic)with right understanding. We are not safe and free from the terrorism yet.

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Utilization Level and Associated Factors of Complementary and Alternative Medicine in the Older Population before Death (사망 전 노인들의 보완대체요법 이용수준 및 관련 요인)

  • Cho, Nam-Hong;Woo, Eun-Kyung;Yi, Jee-Joen;Yi, Sang-Wook;Cho, Hang-Sok;Kim, Sun-Hyun
    • Journal of Hospice and Palliative Care
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    • v.7 no.1
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    • pp.37-48
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    • 2004
  • Purpose: Population using complementary and alternative medicine (CAM) and the cost or it are increasing all over the world. In this study, we investigated the utilization state of CAM in the elderly people during the last 6 months of life. Methods: We found 4,210 persons in Seoul, older than 65 years who received a funeral subsidy from health insurance after death during the latter half of the year, 2001. We stratified them by age and gender and selected 301 persons and surveyed them by questionnaire. Results: 247 persons (83.1%) used at least one of CAM during their last 6 months of life. Diet and Nutrition remedy showed the highest utilatization rate (65.5%), and drug therapies also were much used (29.9%). Utilization rate was higher in female (60%) and according to the cause of death, the highest in a geriatric disease groups, and the lowest in the cancer group. Whole satisfaction to CAM was high with average 4.25 points out of total 6, and adverse effects were almost free with average 5.55 points out of total 6. Satisfaction was the highest in Diet and Nutrition remedy but the lowest in Manipulative and Body-Based methods. Adverse-effect score was best in Manipulative and Body-Based methods. According to age and the causative disease of death, there were significant differences in satisfaction and adverse effect levels. Conclusion: Majority of old people used at least one of CAM during their last 6months of life. Whole satisfaction and adverse-effect level were very excellent.

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A Case Study of Geumho River Basin for Integrated Flood Management (통합홍수관리를 위한 금호강유역 사례연구)

  • Ko, Jin-Seok;Choi, Eun-Hyuk;Keum, Do-Hun;Jee, Hong-Kee
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.800-804
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    • 2007
  • 전 세계에서 홍수로 인한 인명손실과 재산적 피해의 기록을 살펴보면 최근 몇 년 동안 꾸준히 증가하고 있다. 이로 인해서 홍수를 방어하기 위한 노력은 증가하게 되었다. 이로 인해 홍수터에서 인구집중과 개발로 인해 홍수방어를 위해서 막대한 투자가 필요하다. 이와 동시에 지속가능하고 효과적인 수자원 관리는 전체적인 접근방법이 요구되며, 사회와 경제발전과 생태계 보호 및 토지이용과 수자원 이용의 적절한 관리와 연결된 개념이 필요하다. 유역은 육지와 수계 사이의 많은 상호작용이 있는 동적인 시스템이다. 이러한 관점에서 유역을 간단한 고정된 지역적인 문제라고 생각하는 것보다 전체로서의 유역 기능을 개선하는데 노력이 필요하고 시도되어야 할 것이다. 통합홍수관리(IFM : Integrated Flood Management)는 홍수의 긍정적인 측면과 부정적인 측면을 고려한 새로운 접근방법이며, 홍수가 자원적 가치를 지닌 것이라고 생각하는 개념이다. 통합홍수관리의 특징은 홍수조절 대책의 적절한 혼합, 대책의 목적 및 형태(구조적 및 비구조적 대책), 단기간 및 장기간 대책 등의 대책들을 통합하는 것이다. 여기에는 전유역의 수문순환 관리, 통합 토지이용 및 수자원 관리, 최적 혼합대책의 적용 및 통합재해관리 적용 등이 있다. 홍수는 자연적인 수문학적 체계의 중요한 요소이며, 주요 수자원이기도 하다. 그리고 빈번한 홍수로 인해 제방을 넘어 홍수터를 점령한다. 이 결과로 상습 홍수범람지역은 점점 더 인구가 밀집되고 있고 홍수에 더 취약하게 된다. 그러므로 금호강유역에 발생한 홍수의 개요, 원인 및 결과에 대해서 살펴보고, 홍수관리대책과 실효성에 대해서 조사 분석하였다. 그리고 홍수가 발생한 후 홍수관리대책과 관리기술의 변화를 통합홍수관리의 개념에서 분석하였다.Jones matrix, which allows a new interpretation in the conversion efficiency of the thin-film optical waveguides.있다는 장점이 있었다. 따라서 소아에서 복막투석도관 수술 시 복강경적 방법을 이용하는 것이 효율적인 복막 투석을 위해 유용하다고 생각된다.상부 방광천자에 비해 민감도 59.5%(25/42), 특이도 86.6%(13/15)였고 위양성률 13.3%(2/15), 위음성률 40.5%(17/42) 로 정확도가 낮았다. 결론 : 소변을 가리지 못하는 영유아에서 요로 감염을 진단하기 위해서는 도뇨관 채뇨에 비해 초음파 감시하 치골상부 방광천자가 정확하고 안전한 채뇨법으로 권장되어야 한다고 생각한다.應裝置) 및 운용(運用)에 별다른 어려움이 없고, 내열성(耐熱性)이 강(强)하므로 쉬운 조건하(條件下)에서 경제적(經濟的)으로 공업적(工業的) 이용(利用)에 유리(有利)하다고 판단(判斷)되어진다.reatinine은 함량이 적었다. 관능검사결과(官能檢査結果) 자가소화(自家消化)시킨 크릴간장은 효소(酵素)처리한 것이나 재래식 콩간장에 비하여 품질 면에서 손색이 없고 저장성(貯藏性)이 좋은 크릴간장을 제조(製造)할 수 있다는 결론을 얻었다.이 있음을 확인할 수 있었다.에 착안하여 침전시 슬러지층과 상등액의 온도차를 측정하여 대사열량의 발생량을 측정하고 슬러지의 활성을 측정할 수 있는 방법을 개발하였다.enin과 Rhaponticin의 작용(作用)에 의(依)한 것이며, 이는 한의학(韓醫學) 방제(方劑) 원리(原理)인 군신좌사(君臣佐使) 이론(理論)에서 군약(君藥)이 주증(主症)에 주(主)로 작용(作用)하는 약물(藥物)이라는 것을 밝혀주는 것이라고 사료(思料)된다.일전 $

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BORDERLINE DISORDER OF CHILDHOOD : 8 CASES (아동기 경계선 장애 : 8증례)

  • Hong, Kang-E;Lee, Jeong-Seop;Shin, Min-Sup
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.6 no.1
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    • pp.3-17
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    • 1995
  • The so-called borderline children are characterised by disturbances in the sense of reality and interpersonal relationships, lack of control, fluctuation of functioning, uneven development and excessive anxiety. But the concept of borderline disorder of childhood is very difficult to define and diagnose in current classification system. The present study adapted the consensus symptoms in borderline children by Bemporad and Vera eight cases aged 7-11 were examined in 37 variables. Results are as follows 1) All subjects are boys and girl hardly be diagnosis n current diagnostic system and have many concurrent diagnoses. Common chief complaints in the sense of reality. 2) In KEDI-WISC test, the borderline children showed average intelligence, but performance IQ tends to be higher than verbal IQ. In Rorscharch test, they showed high thought disorder index, emotional instabilities and aggressive impulses. The results of TOVA suggested attentional deficit in half of the subjects. The organicity is not prominent. 3) Many of the borderline children were unwanted baby. Although primary care takers of all the subjects were their mothers there were moderate problems in caring attitude of their children and marital relationship with their husband. Sccioeconomic status was generally below middle class. Most of all subjects have delayed language development, but have overcome subsequently. Many subjects were rejected by peers because of their aggression. 4) The first visit of the subjects was about 6 years of age. Average duration of treatment was 2 years. All of them were treated in the outpatient basis except one. The effect of pharmacotherapy was doubtful and the necessity of long term play therapy was suggested. Although there were many limitations of method in present study, it was suggested that further research is needed for diagnostic criteria, epidemiology and treatment.

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The Estimation of IDF Curve Considering Climate Change (기후변화를 고려한 IDF곡선 추정방안에 대한 연구)

  • Kim, Byung-Sik;Kyoung, Min-Soo;Lee, Keon-Haeng;Kim, Hyung-Soo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.774-779
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    • 2007
  • IDF 곡선은 전통적으로 지점에서의 과거 관측 강우량 시계열 자료를 수집하여 작성하여 왔으며, 이때 과거 강우량 자료는 정상성을 지니고 있고 미래를 대변한다는 가정을 전제로 한다. 그러나 이미 많은 연구자들에 의해 기후변화가 전구적으로 발생하고 있으며 우리나라에서도 더 이상 기후변화의 사실여부는 이제 더이상 논란 꺼리가 아니다. 특히, 기후변화의 영향을 직접적으로 받을 수밖에 없는 수자원 분야에서는 1990년대부터 잦은 홍수와 가뭄의 반복으로 곤란을 겪고 있다. 특히, 우리나라는 협소한 국토면적과 과다한 인구로 토지나 수자원 등 국토자원 이용의 강도가 다른 나라에 비하여 현저하게 높기 때문에 지구온난화에 따른 기후변화와 같은 약간의 기후변동으로도 심각한 문제가 발생할 가능성이 내포되어 있다. 특히, 기후변화는 유역 규모의 강우 발생 패턴과 강우량의 증가 및 감소에 영향을 미치게 되며 이로 인해 강우 시계열 자료는 비정상성과 경향성을 지니게 된다. 그러나 지금까지는 IDF 곡선의 작성시 강우의 경향성을 무시해 왔다. 본 연구에서는 기후변화가 IDF 곡선에 미치는 영향을 분석하기 위하여 GCM 기후변화 시나리오를 이용하여 IDF 곡선을 작성하였다. 이를 위하여 먼저, YONU CGCM의 제한실험과 점증실험을 실시하여 전구적 규모의 기후변화 시나리오를 작성하였으며, 통계학적 축소기법과 추계학적 일기발생기법을 이용하여 대상지점의 일 수문기상 시계열을 모의하였다. 그리고 BLRP(Bartlett Lewis Rectangular Pulse) 모형과 분해(koutsoyiannis, 2000) 기법을 이용하여 모의된 일 강우 자료를 시자료로 분해하였으며 이를 이용하여 IDF 곡선을 작성하였다. 그 결과, 기후변화 시 지속기간별 재현기간별 강우량이 현재에 크게 비해 증가됨을 확인할 수 있었다.으며 여러명이 동시에 서버에 접속을 하기 때문에 컴퓨터에 부하가 많이 걸리는 모델링이나 복잡한 분석은 실시하기 어려우며, 대용량 데이터를 전송할 수 있는 대역폭이 확보 되어야 한다. 또한, Internet 환경으로 개발을 해야되기 때문에 데스크탑용 GIS에 비해 개발속도가 느리며 개발 초기비용이 많이 들게 된다. 하지만, 네트워크 기술의 발달과 모바일과의 연계 등으로 이러한 약점을 극복할 수 있을 것으로 판단된다. 따라서 본 논문에서는 인터넷 GIS를 이용하여 홍수재해 정보를 검색, 처리, 분석, 예경보할 수 있는 홍수방재정보 시스템을 구축토록 하였다.비해 초음파 감시하 치골상부 방광천자가 정확하고 안전한 채뇨법으로 권장되어야 한다고 생각한다.應裝置) 및 운용(運用)에 별다른 어려움이 없고, 내열성(耐熱性)이 강(强)하므로 쉬운 조건하(條件下)에서 경제적(經濟的)으로 공업적(工業的) 이용(利用)에 유리(有利)하다고 판단(判斷)되어진다.reatinine은 함량이 적었다. 관능검사결과(官能檢査結果) 자가소화(自家消化)시킨 크릴간장은 효소(酵素)처리한 것이나 재래식 콩간장에 비하여 품질 면에서 손색이 없고 저장성(貯藏性)이 좋은 크릴간장을 제조(製造)할 수 있다는 결론을 얻었다.이 있음을 확인할 수 있었다.에 착안하여 침전시 슬러지층과 상등액의 온도차를 측정하여 대사열량의 발생량을 측정하고 슬러지의 활성을 측정할 수 있는 방법을 개발하였다.enin과 Rhaponticin의 작용(作用)에 의(依)한 것이며, 이는 한의학(韓醫學) 방제(方劑) 원리(原理)인 군신좌사(君臣佐使) 이론(理論)에서 군약(君藥)이 주증(主症)에 주(主)로 작용(作用)하는 약물(藥物)이라는 것을 밝혀주는 것이라고 사료(思料)된다.일전 $13.447\;{\mu}g/hr/g$, 섭취 7일중 $8.123

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