• Title/Summary/Keyword: 약물지식

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A Comparative Study of the Impacts among Patent Assignees in Pharmaceutical Research based on Bibliometric Analyses (계량서지학적 분석을 통한 약물연구분야 특허출원인 간 영향력 비교)

  • Kim, Heeyoung;Park, Ji-Hong
    • Journal of the Korean Society for information Management
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    • v.39 no.1
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    • pp.1-15
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    • 2022
  • This study analyzes the relationship of citations appearing in the patent data to understand knowledge transfers and impacts between patent documents in the field of pharmaceutical research. Patent data were collected from a website, Google Patents. The top 25 assignees were selected by searching for patent documents related to pharmaceutical research. We identify the citation relationships between assignees, then calculate and compare the values of h-index and derived indicators by using the number of citations and rank for each document of each assignee. As a result, in the case of pharmaceutical research, the assignee, such as 'Pfizer, MIT, and Abbott' shows a high impact. Among the five bibliometric indicators, the g-index and hS-index show similar results, and the indicators are the most related to the rankings of Total Citation Frequency, Cites per Patents, and Maximum Citation Frequency. In addition, it is highly related to the five indicators in the order of Total Citation Frequency, Cites per Patents, and Maximum Citation Frequency. In some cases, it is difficult to make an accurate comparison with Cites per Patents alone, which is previously known to indicate the technological influence of patent assignees.

The Effects of an Education Program on the Knowledge of Medication and Prevention of Depression in the Elderly with Chronic Disease at a Local Community (지역사회 만성질환노인의 약물사용과 우울예방 교육 프로그램 효과)

  • Kim, Yeong-Ju
    • Research in Community and Public Health Nursing
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    • v.22 no.4
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    • pp.399-408
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    • 2011
  • Purpose: This study was conducted to evaluate the effects of an education program on the knowledge of medication and prevention of depression in the elderly at a local community. Methods: This study utilized the nonequivalent control group pretest-posttest design. Thirty consecutive people were included in this study for the experimental group, and another 30 people were allocated to the control group. The program was performed once a week for 3 weeks. Data were collected from March 15 to April 30, 2010 and statistical analyses were performed by ${\chi}^2$-test and independent t-test using the SPSS/WIN 12.0 program. Results: There were statistically significant differences in the knowledge of medication, depression and medication compliance between the experimental and control groups. Conclusion: This study demonstrated that an education program for the knowledge of medication and prevention of depression in the elderly with chronic disease could improve their knowledge of medication and their medication compliance, and decrease their depression. These results suggest that education of knowledge with social psychology can be an effective and practical method of management to the elderly with chronic disease at local communities.

The Effect of Drug Abuse Prevention Program for Elementary School Students (초등학생을 위한 약물남용예방 프로그램의 적용 효과)

  • 성정혜;박정숙
    • Journal of Korean Academy of Nursing
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    • v.34 no.3
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    • pp.421-429
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    • 2004
  • Purpose: This study is to evaluate the effects of drug abuse prevention program for elementary school students. Method: The design of this study is nonequivalent control group pretest-posttest design. The subjects of experimental group were 27 students and the subjects of control group were 25 students in fifth grade of elementary school in C City, Gyeongsangbuk-do. The experimental group had Drug Abuse Prevention Program, which was two days per week program, for 5 weeks. And post-test was carried out in the same way as the pre-test. Data analysis was done using frequency, percentage, mean, standard deviation, Chi-square test, t-test, Paired Samples t-test using with SPSS WIN 11.0. Result: the experimental group, to which drug abuse prevention program was given, was improved in knowledge of drug and unacceptable attitude of drug compared to the control group, but there were no significant differences of self-esteem and assertiveness between two groups. Conclusion: The drug abuse prevention program was effective to increase knowledge and attitude of drug in elementary school students.

The Effects of Planned Discharge Nursing in Compliance, Knowledge, and Nursing Service Satisfaction for Patients having Video-Assisted Thoracoscopic Surgery (계획된 퇴원 간호 중재가 기흉 수술 환자의 약물복용 및 치료 지시 이행도, 질병에 대한 지식과 간호 만족도에 미치는 효과)

  • Lee, Won Jin;Bang, Yun Yi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.11
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    • pp.121-129
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    • 2019
  • This study aimed to develop a planned discharge nursing intervention guideline for patients with pneumothorax, and to examine its influence on drug compliance, knowledge about disease, compliance level with therapeutic regimen, and nursing satisfaction. Methods: The planned discharge nursing intervention guideline was developed based on comprehensive literature reviews and clinical experiences. Patients having video-assisted thoracoscopic surgery at a single general hospital were allocated to either intervention (n=30) or control group (n=29). Participants in the intervention group were administered planned discharge nursing intervention thrice, 30 minutes each, by a cardiovascular nurse. Standard care was provided to patients in the control group. Data were collected from March, 2010 to December, 2010. Results: Participants in the intervention group presented statistically significant improvement in drug compliance (t=-2.05, p=0.044), pill count (t=-2.61, p=0.011), knowledge about disease (t=-4.39, p=0.001), and nursing satisfaction (t=-4.13, p=0.001). No significant difference in compliance levels was observed with standard therapeutic regimen. Conclusion: Planned discharge nursing intervention can be successfully implemented for patients undergoing thoracoscopic surgery. Further research is required to evaluate long-term effects like complication or relapse.

Delirium Management: Diagnosis, Assessment, and Treatment in Palliative Care (섬망의 돌봄: 완화의료 영역에서의 진단, 평가 및 치료)

  • Seo, Min Seok;Lee, Yong Joo
    • Journal of Hospice and Palliative Care
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    • v.19 no.3
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    • pp.201-210
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    • 2016
  • Delirium is a common symptom in patients with terminal cancer. The prevalence increases in the dying phase. Delirium causes negative effects on quality of life for both patients and their families, and is associated with higher mortality. However, some studies reported that it tends to remain unrecognized in palliative care setting. That may be related with difficulties to distinguish the symptom from others with overlapping characteristics such as depression and dementia, and a lack of knowledge regarding assessment and diagnostic tools. We suggest that accurate recognition with validated tools and early diagnosis of the symptom should be highly prioritized in delirium management in palliative care setting. After diagnosing delirium, it is important to identify and address reversible precipitants such as medication, dehydration, and infection. Non-pharmacological interventions including comfortable environment for the patient and family education are also essential in the management strategy. If such interventions prove ineffective or insufficient to control hyperactive symptoms, pharmacologic interventions with antipsychotics and benzodiazepine can be considered. Until now, low levels of haloperidol remains the standard treatment despite a lack of evidence. Atypical antipsychotics such as olanzapine, quetiapine and risperidone reportedly have similar efficacy with a stronger sedating property and less adverse effect compared to haloperidol. Currently, delirium medications that can be used in palliative care setting require more clinical trials, and thus, clinical guidelines are not sufficiently available. We suggest that it is warranted to develop clinical guidelines based on well-designed clinical studies for palliative care patients.

The Survey on the Drug use status, Knowledge and Attitude of College Students (Seoul and Northern Part of the Kyunggi-do) (대학생의 약물 사용 실태.지식 및 태도(서울 및 경기 북부지역))

  • Han, Kyoung-Soon;Moon, Sun-Young;Park, Hyun-Ok;Park, Eun-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.6 no.2
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    • pp.376-389
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    • 2000
  • The Purpose of this study was to grasp the status of drug uses in college students, and to investigate the knowledge and attitude when they use it. We collected through questionnaires from Sep. 1 to Oct. 30 in 1999. The subjects were 490 college students in Seoul and northern of the Kyunggi-do. The data analysis was performed using SPSS (version 7.0) and ANOVA. The results of this study were as follows. 1. There was no correlation for all factors in the relationship between general characteristics of subjects and knowledge for drugs. On the contrary, in the relation of the general characteristics and attitude for drug of subjects, some factors are statistically significant e.g., department (F=3.049, p<.010), satisfaction for school life (F=6.167,p<.002), body shape(F=8.092, p<.000), and the relationship with ones parents (F=3.728, p<.005). 2. In the analysis of drug use status and knowledge, only in the factor of administration control was statistically significant(F=4.304, p<.014) and in the relation of attitude for drug uses, drug administration was statistically significant (F=4.521, p<.004). 3. In the mean scores for the drug knowledge analysis, the highest factor was 'A narcotic make deformed persons through poisoning of physical and mental' (M=4.14), the lowest factor was 'If catch the flu during the pregnancy, should be take drug as possible as quickly to reduce negative effect for fetal' (M=1.94). 4. In the analysis for drug attitude, the highest factor was 'A drug is alike a poison' (M=3.48), 'Should be keep the usage and dosage of drug' was the lowest (M=1.48). 5. From the investigation for status of drug use, it was revealed that the most subjects (73.6%) were purchase drugs after explain their symptoms to pharmacist. And they take drugs only when they felt painful in 43.1%. The most students (70.4%) were experienced control of drug administration. It was inquired that subjects were mainly obtained information about drugs from pharmacist and television (or radio) advertisement, 33.5% and 33.1%, respectively. In the examination for existence of long-term administrators in their family, 'none' and 'only parents' are 49.6% and 37.3%, respectively. When their parents have illness, the persons go to drugstore and hospital for heath-care, 47.8% and 44.3%, respectively. On the basis of results of this study, we suggest as follows. 1. This study was analyzed data from questionnaires for college students in a part of local areas, so we suggest that the next research should be perform for national-wide students as subjects to generalize the results. 2. It is need more intensive research methodologies such as interview and observation. 3. Additional research is required for knowledge and behaviors of drug uses that will how impact on ones health behavior.

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DENTAL CARE FOR PEOPLE WITH A MENTAL HANDICAPS (정신지체인의 치과관리)

  • Lee, Keung-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.33 no.1
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    • pp.149-159
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    • 2006
  • 과거 정신지체는 사회의 불가사의한 것이었으나 현재는 이들의 원인과 병리현상의 이해로 예방과 의학적 관리에 괄목할 만한 발전이 이루어져 왔다. 그러나 이들 정신지체인의 치과관리는 과거와 별다른 변화를 이루지 못한 것이 우리의 현실이다 이들에 관심을 갖고 치료하기 원하는 치과의사들도 아직 진단이나 치료방법에 이용이 제한되어있다 정신지체인 들에게도 정상화 개념을 도입해 보다 나은 건강관리 환경을 이루도록 시대가 바뀌어 가고 있다. 환자의 권리를 보장키 위해 수용시설 입소화. 물리적인 강제치료 등 기존의 일반적인 행위에서 탈피하여 이제는 행동조절의 차원에서 약물이용과 치과적용에 필요한 모든 지식의 습득이 필수적인 것으로 변화되고 있다.

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Research on Identifying Mutation-Drug Relationship in Biomedical Literature Using Biomedical Context based pre-trained word embedding (의생명과학 기반 기학습된 워드 임베딩을 이용한 의생명과학 논문 속의 돌연변이-약물 관계 추출 연구)

  • Kim, Hojun;Won, Seongyeon;Gang, Seungwoo;Lee, Kyubum;Kim, Byounggun;Kim, Sunkyu;Kang, Jaewoo
    • Proceedings of the Korea Information Processing Society Conference
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    • 2017.04a
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    • pp.774-777
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    • 2017
  • 의생명과학분야가 계속 발전됨에 따라 매일 평균 3천여 편에 달하는 방대한 양의 의생명과학분야 문헌들이 나오고 있다. 많은 연구가 진행될수록, 새로이 규명된 관계를 습득하고 체계화하는 일이 연구자와 의료계 종사자들에게 더 중요해지고 있다. 하지만 현재로서는 의생명과학분야에 어느 정도의 지식이 있는 사람이 직접 논문을 읽고 해당 논문에서 밝히고 있는 정보를 정리해야만 하는 상황이며, 이로는 기하급수적으로 쌓이는 정보의 양을 대처하기 어렵다. 이를 해결하기 위해 본 논문에서는 기계 학습을 통한 생명의료 객체관계 자동추출 연구를 이용하여 의생명과학분야의 정보를 체계화 하고자 한다. 본 논문에서는 돌연변이와 약물이 함께 등장하는 논문을 뽑아내어 글을 자연어 문장 단위로 나누었다. 추출한 돌연변이와 약물 간의 관계를 직접 사람에 의해 참거짓을 판명하였고, 해당 데이터셋을 기계학습에 이용하여 돌연변이와 약물 간의 관계를 학습시켰다. 최종적으로 GoogleNews의 기사들로 기학습된 워드임베딩, 의생명과학분야 문헌들을 이용하여 기학습된 워드임베딩을 이용하여 학습의 성능을 비교하였고, 의생명과학-문맥 특이적인 워드임베딩이 갖는 강점을 보고한다. 해당 연구를 통해 실제로 논문을 읽지 않고도 의생명과학분야 논문의 핵심적인 내용을 뽑아내는 자동화 시스템을 구축하는 데에 이바지하고, 의생명공학 연구자들의 연구에 핵심적인 도움이 되는 디딤돌이 되고자 한다.

Effects of a Drug Misuse and Abuse Prevention Program on Knowledge, Attitude, and Preventive Behaviors Related to Drug Misuse and Abuse, and Depression in Low-income Elderly Women (약물 오$\cdot$남용 예방프로그램이 저소득 여성노인의 약물 오$\cdot$남용 예방에 대한 지식, 태도, 예방행위 및 우울에 미치는 효과)

  • Shin Kyung-Rim;Kim Jeong-Sun;Kim Jin-Young;Yi Hye-Ryeon
    • Journal of Korean Academy of Nursing
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    • v.35 no.5
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    • pp.763-773
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    • 2005
  • Purpose: This study was conducted to determine the effects of a drug misuse and abuse prevention program on knowledge, attitude, and preventive behaviorsrelated to drug misuse and abuse, and depression in low-income elderly women in the urban area. Method: The design of this study was a nonequivalent control group pretest-posttest design. The subjects consisted of 26 in the experimental group and 23 in the control group. The program was performed for about 1 hour, once a week for 5 weeks. Data was analyzed by the SAS(ver.8.02) computer program, and it included descriptive statistics, Fisher's exact test, Mann-Whitney U test, Wilcoxon signed ranks test, and ANCOVA. Result: There were statistically significant differences in knowledge, attitude, and preventive behaviors related to drug misuse and abuse, and depression between the experimental group and the control group. Conclusion: This study showed that this prevention program of drug misuse and abuse is appropriate for low-income elderly women, Therefore this program is recommended as a nursing intervention strategy for the elderly.

Survey of Knowledge on Insomnia for Sleep Clinic Clients (수면클리닉을 방문한 환자들의 불면증에 대한 인식조사)

  • Soh, Minah
    • Sleep Medicine and Psychophysiology
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    • v.26 no.1
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    • pp.23-32
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    • 2019
  • Objectives: Insomnia is not only the most common sleep-related disorder, but also is one of the most important. Knowledge of the comorbidities of insomnia is essential for proper treatment including pharmacological and non-pharmacological methods to prevent disease chronification. This study aimed to determine sleep clinic patients' knowledge of insomnia. Methods: This study recruited 44 patients (24 males and 20 females; mean age $54.11{\pm}16.30years$) from the sleep clinic at National Center for Mental Health. All subjects were asked to complete a self-report questionnaire about their reasons for visiting a sleep clinic and about their knowledge of treatment and comorbidities of insomnia. Results: The reasons for visiting the sleep clinic were insomnia symptoms of daytime sleepiness, irregular sleeping time, nightmares, snoring, and sleep apnea, in that order. Of the responders, 72.7% had a comorbidity of insomnia, and 22.7% showed high-risk alcohol use. In addition, 70.5% of responders chose pharmacological treatment of insomnia as the first option and reported collection of information about treatment of insomnia mainly from the internet and medical staff. More than half (52.3%) of the respondents reported that they had never heard about non-pharmacological treatments of insomnia such as cognitive behavioral treatment (CBT-I) or light therapy. The response rate about comorbidities of varied, with 75% of responders reporting knowledge of the relation between insomnia and depression, but only 38.6% stating awareness of the relation between insomnia and alcohol use disorder. Of the total responders, 68.2% were worried about hypnotics for insomnia treatment, and 70% were concerned about drug dependence. Conclusion: This study showed that patients at a sleep clinic had limited knowledge about insomnia. It is necessary to develop standardized insomnia treatment guidelines and educational handbooks for those suffering from insomnia. In addition, evaluation of alcohol use disorders is essential in the initial assessment of sleep disorders.