• Title/Summary/Keyword: 약리성분

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Changes of Paeonol and Paeoniflorin Contents in Chinese Moutan (Paeonia suffruticosa Andrews) Cultivars with Different Harvesting Times and their Parts (중국 목단재배종의 채취시기 및 부위별 Paeonol과 Paeoniflorin의 함량변화)

  • Choi, Kyung;Zhao, Fei;Li, Yuhua;Choi, Jun-Won;Lee, Hak-Ju;Kwon, Yeong-Han;Park, Kwang-Woo
    • Korean Journal of Medicinal Crop Science
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    • v.13 no.1
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    • pp.35-40
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    • 2005
  • We analyzed six cultivars of Chinese Moutan, Paeonia suffruticosa Andrews, using HPLC for the investigation of appropriate root harvesting time and distributions of paeonol and paeoniflorin according to the seasonal changes. The contents of paeonol remained nearly constant at different harvesting times. However, the paeoniflorin contents have changed significantly during the harvesting time. These showed the increasing tendency in May, July and September. We compared the distribution of two compounds between two cultivars with different flower forms, Dan Feng and Wu Long Feng Sheng. The contents of paeonol were very low in the leaf and annual shoot. This tendency was not changed during five harvesting times. But the paeoniflorin existed abundantly in the leaf and root. The contents of paeoniflorin in the leaf were highest in May, and gradually decreased.

Quantitative Analysis of ${\gamma}-oryzanol$ in Rice Bran (미강의 약리성분 감마-오리자놀의 정량)

  • Kwak, Tae-Soon;Park, Hee-Juhn
    • Korean Journal of Medicinal Crop Science
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    • v.5 no.2
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    • pp.113-118
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    • 1997
  • Phytochemical analysis on rice bran and its pitch was performed by the tool of TLC, UV- and IR-spetroscopy, so that it was found that they contained ${\gamma}-oryzanol$ and free sterol. GC-MS analysis of free sterol revealed that it was composed of ${\beta}-sitosterol$, campesterol and stigmasterol. Successive phytochemical analysis of ${\gamma}-oryzanol$ revealed that it was composed of ferulic acid ester of triterpene and sterol, respectively. Triterpene moieties of ${\gamma}-oryzanol$ were identified as follows: cycloartanol, cycloartenol, 24-methylenecycloartanol and unknown triterpene; And sterol moieties were found to be identical with free sterols. In addition, characteristic absorption band in UV spectrum (220-340 nm) was exclusively due to ${\gamma}-oryzanol$. Thus, it was suggested that rice brans of nearly all species of Oryza sativa can be quantitatively analyzed by UV absorption spectrometry, even when water soluble pigments was contained in the rice bran.

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The Studies of Component and Pharmacologic Action on Dianthus sinensis L. (구맥(瞿麥) Dianthus sinensis L.의 성분(成分) 및 약리작용(藥理作用)에 관(關)한 연구(硏究) ( I ))

  • Han, Dae-Sup;Ko, Kye-Chang;Jung, Jee-Chang
    • The Korean Journal of Pharmacology
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    • v.8 no.2
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    • pp.49-54
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    • 1972
  • The component and pharmacologic action on Dianthus sinensis L. were investigated as follows: 1) The components of Dianthus sinensis L. were suggested 8 kind of components by means of thin layer chromatography and paper chromatography. The one of them were suggested as a steroidal saponin by means of IR-spectrum and Liebermann-Burchard, Salkowiski, $SbCl_3$ reaction. 2) Sodium level in serum were reduced by administration of the sample to the rabbits, while in urine were elevated. 3) Blood sugar level of normal rabbits administered with sample, no significant variation were detected. 4) When the hyperglycemic rabbits treated with alloxan were administered sample, blood-sugar level were significantly decreased than control group.

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The Pharmacological Study on Ginkgoic Acid, a Component of Ginkgo Biloba L. Fruit (은행성분(銀杏成分) Ginkgoic Acid의 약리학적(藥理學的) 연구(硏究))

  • Han, Dae-Sup
    • The Korean Journal of Pharmacology
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    • v.8 no.1
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    • pp.27-30
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    • 1972
  • The effect of the Ginkgoic acid on the amounts of total cholesterol and triglycerides in serum from rabbit was observed. Ginkgoic acid was obtained from Ginkgo biloba L. fruits, and it was subcutaneously administered to the three days fasted rabbits. After three days starvation, the amounts of total cholesteral and triglycerides in serum of the rabbit were markedly increased. The increased amounts of total cholesteral and triglycerides were gradually decreased by administration of Ginkgoic acid, and were returned to the control levels after 4 days. According to the above results, it would be concluded that Ginkgoic acid influences for the recovery of the increased amounts of total cholesterol and triglycerides by abnormal metabolism to normal on rabbit.

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A Quality Characteristic in Schisandra chinensis by Puff processing (팽화처리에 의한 오미자의 품질 특성)

  • Nam, Hyeon-Hwa;Choo, Byung-Kil
    • Korean Journal of Organic Agriculture
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    • v.24 no.4
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    • pp.893-905
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    • 2016
  • Puff processing is one of the preparation and processing methods of herbal medicines. This study analyzed the quality characteristics in schisandra chinensis extracts by puff processing ($1kgf/cm^2$, $3kgf/cm^2$, $5kgf/cm^2$) through changes of the lignan contents and antioxidant activity. The lignan contents and antioxidant activity of puff processing schisandra chinensis extracts (PPSCE) increased higher than compared to a control. Also, as lignan contents and antioxidant activity of PPSCE was increased with the increasing pressure but it was reduced from $5kgf/cm^2$. The results suggest that puff processing was attributed to the quality increase schisandra chinensis.

Dyability of Silk Fabrics with Juniperus chinenesis Extracts by Solvents (용매에 따른 향나무 부위 별 색소 추출물의 견직물에 대한 염색성)

  • Lee, Jung-Soon;Nam, Ki-Yeon
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2012.03a
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    • pp.69-69
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    • 2012
  • 지구상에는 약 40만 종의 식물이 존재하는 것으로 알려져 있으며 이 중에 는 질병의 치료를 위한 약재로 이용되거나 나무는 대부분 목재 등으로 이용된다. 향나무(Juniperus chinenesis L.)는 항균성 및 방충성이 뛰어난 상록수로서 목재는 조각재나 가구재로 사용되고 민간 및 한의학에서 다양한 증상의 약재로 쓰이고 있으며 부패한 냄새를 제거할 목적이나 향재 및 향료로도 쓰이고 있다. 열매의 정유성분은 화장품, 술, 캔디 등에 사용되며 cedrol은 향료보류제, 유분은 훈향료, 목부는 고혈압, 곽란, 심복통, 통기파혈에 쓰인다. 향나무는 폴레페놀 성분이 함유되어 있고 피톤치드가 많이 나오는 것으로 알려져 있으며 심재의 폴리페놀 화합물은 항암, 항균, 항알러지, 노화방지 및 심장질환 등을 예방하거나 지연시키는 등 광범위한 약리학적 활성을 나타내어 식품, 의약품, 화장품, 향료등 다양한 분야에 활용되고 있다. 향나무 추출물에 관한 연구로는 성분분석과 생리활성 등에 관한 의약학 분야의 다양한 연구와 항산화, 항균활성 등 약리작용에 연구가 최근 다양하게 이루어지고 있는 것을 볼 수 있다. 측백나무속에 속하는 나무들은 대부분 정유 성분을 함유하고 있는 특성으로 항균성 등 바이오 기능성 소재 개발을 위한 연구가 활발히 진행되고 있으나, 향나무 추출물의 염색성에 관한 연구는 찾아보기 어려운 실정이다. 이에 본 연구에서는 다양한 용매를 이용하여 향나무의 잎, 열매, 수피, 심재 각 부위 추출물을 이용하여 견직물에 대한 염색성을 살펴봄으로써 향나무 추출물을 활용한 천연염색과 염재로서의 가능성을 확인하고자 하였다. 실험 결과 증류수를 염액 용매로 염색한 결과 모든 추출물의 잎, 열매 염색포의 색상은 대부분 옅은 Y계열로 나타났으며 향나무의 수피와 심재 염색포는 대부분 적색기미가 강한 YR계열로 나타났다. 에탄올 혼합액을 염액 용매로 하여 염색한 결과 향나무의 잎과 열매의 색상은 대부분 Y계열의 색상을 나타냈고 유기용매 추출염색포에서 정유성분으로 추정되는 물질 때문에 균염이 어려웠으며 수피와 심재 염색포에서 대부분 R계열의 색상이 뚜렷이 나타났다.

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Component Comparison in Different Growth Stages and Organs of Saururus chinensis $B_{AILL}$. (삼백초의 생육 시기 및 부위별 성분 함량 비교)

  • Lee, Seong-Tae;Park, Jeong-Min;Lee, Hee-Kyoung;Kim, Man-Bae;Cho, Ju-Sik;Heo, Jong-Soo
    • Korean Journal of Medicinal Crop Science
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    • v.8 no.4
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    • pp.312-318
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    • 2000
  • To obtain the basic information for commercial process and high quality production of Saururus chinensis, useful components were determined at different growth stages and organs. The contents of quercetin, quercitrin and tannin at different growth stages were decreased before flowering time but slightly increased after flowering. The contents of quercetin, quercitrin and tannin collected on July 26 were 5.72, 5.45g/kg and 1.5%, respectively. The contents of quercetin, quercitrin and tannin were the highest in white leaf, leaf and flower, respectively.

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Differences of Major Compounds in Valerian fauriei var. dasycarpa HARA and Valerian officinalis L. Grown at Different Places in Korea (광릉쥐오줌풀과 넓은잎쥐오줌풀의 산지별 유효성분의 변화)

  • Cho, Chang-Hwan;Choi, Young-Hyun;Kim, Kun-Soo;Ahn, Tae-Jin;Han, Ok-Kyu
    • Korean Journal of Medicinal Crop Science
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    • v.4 no.2
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    • pp.109-113
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    • 1996
  • This study was conducted to know the effect of cultivation area with different sea levels on essential oil content and its composition and content of major active compounds in Valerian fauriei var. dasycarpa HARA and Valerian officinalis L. The total contents of essential oil were not different according to the locality in both valerian, however, its compositions were varied. The major components in V. fauriei were detected bornyl acetate and sesquiterpene alcohol in three cultivation areas. The major compounds were borneol, borney acetate, ${\beta}\;-sesquiohellandrene$ in V. officinalis other. Among the valepotrate components known as major pharaceutically active components in Europe and Nepal valerian, valtrate was detected in a small amount in V. fauriei, but its quantity was not changed according to the cultivation area.

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Effects of Diallyl Disulfide on the Hepatic Glutathione Peroxidase Activity in Rat (흰쥐 간 Glutathione peroxidase 활성에 미치는 Diallyl disulfide의 영향)

  • Huh, Keun;Lee, Sang-Il;Park, Jong-Min
    • The Korean Journal of Pharmacology
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    • v.22 no.2
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    • pp.144-150
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    • 1986
  • Glutathione peroxidase might play an important role in the protection of cellular structures against oxidative challange by hydrogen peroxide and several organic hydroperoxides. It is widely accepted that allicin is biological active component of garlic, and allicin is easily degraded to diallyl disulfide and other components. This study was attempted to elucidate the effect of diallyl disulfide on some biological activities. It was observed that the activity of serum transaminase and glutathione level in liver were not changed by the treatment of diallyl disulfide. The liver cytosolic glutathione peroxidase activity was significantly enhanced. Whereas, mitochondrial enzyme activity was slightly increased. In the presence of diallyl disulfide in vitro, $V_{max}$ value of glutathione peroxidase for hydrogen peroxide was increased. On the other hand, Km value was not changed.

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