• Anatomy & Biological Anthropology
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• v.26 no.1
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• pp.41-49
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• 2013

Dental epithelial and mesenchymal cells that form the teeth undergo dynamic changes in cell cycle during tooth development and morphogenesis. Although proliferation has been known as a key event during odontogenesis, the cell cycle phases and their relations with the complicated molecular mechanisms of tooth development are not fully understood yet. This study comparatively examined the expression patterns of Ki-67, cyclin A, and cyclin D1 during tooth development in the mouse incisor and molar in order to identify the cell-cycle characteristics during odontogenesis. We found that Ki-67 and cyclin A were expressed in the proliferating cells in the dental epithelial and mesenchymal tissues at the bud, cap and bell stages. Cycln D1 showed distinct expression in the incisor odontoblast region and the enamel knot, in which Ki-67 nor cyclin A was expressed. Our results provide specific information on the cell cycle phases during tooth development that may provide clues to relate them with the complex odontogenic mechanisms. Furthermore, we suggest that our findings enlightened the previous studies on the incisor odontoblasts and the enamel knot during tooth development.

• Journal of Chest Surgery
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• v.37 no.10
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• pp.888-891
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• 2004

Basaloid-squamous cell carcinoma, a biologically high-grade variant of squamous cell carcinoma, is predominantly located at upper aerodigestive tract but it is extremely rare in the esophagus. Recently we experienced a case of basaloid-squamous cell carcinoma of esophagus. A 64 year-old man was referred to our hospital because of mucosal nodularity at 35 cm apart from the incisor in endoscopic examination. Result of Biopsy was squamous cell carcinoma. Left transthoracic esophagectomy was performed. Histologically, the lesion of tumor was basaloid-squamous cell carcinoma and no lymph node metastasis was found.

• The Journal of the Korean dental association
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• v.27 no.1 s.236
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• pp.15-18
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• 1989

"62번 보다는 좀 어둡게" 또는 "62번과 65번 사이 정도로"라는 이러한 지시들이 만족스러운 결과를 가져오는가? "선생님, 제 앞니가 이젠 너무 희고 자연스럽지 않아요. 남들이 보면 해 넣은건지 금방 알아요." Porcelain fused to metal crown은 그 심미적 장점 때문에 전치부 수복에 있어 사용이 보편화되어 왔다. 하지만 두께의 제한과 세련되지 못한 일률적인 수복물은 일반적으로 너무 밝고 흰(높은 명도와 낮은 채도) 까닭에 인공적인 것을 쉽게 식별할 수 있으며, 환자들도 하여금 보다 개성화가 요구되어 오고 있다. 이러한 심미적 요구와 함께 최근 우수한 심미성과 높은 강도의 도재전장관들, 즉 Dircor이나 Cera Pearl, Alumina 또는 Magnesia core porcelain등이 연구 개발되어 왔다. 도재 축성술에 있어서도 내장된 첨색효과(internal characterization)나 다층축성법(layer build up)등 많은 방법들이 발전되어 왔다. 자연스러운 도재관을 재현하여 주기 위해서는 먼저 자연치아의 색조에 관한 치과의사의 충분한 인식과 판단이 앞서야 한다. 인식된 색조에 대한 정보가 체계적으로 기록되어 기공사에게 전달되고 재현되어야 한다.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.4
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• pp.474-481
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• 2011

The purpose of this study was to investigate the effect of rigidity of post core systems on stress distribution by the finite element stress analysis method. Three-dimensional finite element models simulating an endodontically treated maxillary central incisor restored with a zirconia crown were prepared. Each model contained cortical bone, trabecular bone, periodontal ligament, 4mm apical root canal filling, and post-and-core. A 50N static occlusal load was applied to the palatal surface of the crown with a $60^{\circ}$ angle to the long axis of the tooth. And three parallel type post (zirconia, glass fiber and stainless steel) and two core (Paracore and Tetric ceram) materials were evaluated, respectively. The differences in stress transfer characteristics of the models were analyzed. von Mises stresses were chosen for presentation of results and maximum displacement and hydrostatic pressure were also calculated. For the Result of the research, the model applied glass fiber to post material has lowest von Mises stress and it is suitable for material of post core systems.

• The Journal of Korean Academy of Prosthodontics
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• v.59 no.2
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• pp.228-237
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• 2021

Physiologic tooth attrition is accepted as a natural change. But when pathologic changes, such as loss of occlusal vertical dimension, masticatory pain, loss of masticatory function, and loss of esthetics occur, restorative measures should be taken by dentist. A patient visited the clinic with the chief complaint of 'My lower teeth bite the palate and it hurts'. It was diagnosed as iatrogenic attrition of lower natural dentition caused by inappropriate upper restorations, resulting in traumatic overbite. Through model analysis and diagnostic wax up, increase in vertical dimension was decided. Upper and lower dentitions were restored with new prostheses. After restoration, satisfactory outcomes were achieved both in functional and esthetic aspects.

• Journal of The Korean Dental Society of Anesthesiology
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• v.7 no.1
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• pp.22-26
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• 2007

상악과 하악이 선천적으로 붙어서 태어나는 선천성 유합증은 드문 선천성 기형으로 단순히 점막이 붙은 점막유합증에서 악골이 붙은 골유합증까지 다양하게 나타난다. 이중 상악골과 하악골의 골자체가 붙는 골유합증은 아주 드물어서 현재까지 26증례만 보고되고 있는데, 보고된 대부분의 증례는 편측에만 발생하는 불완전형으로 알려져 있다. 7세 된 여아환자가 인디아의 GSR 병원에 입이 벌어지지 않는다는 주소로 내원하였는데 환아의 턱은 완전히 움직이지 않았으며, 2-3 mm 정도 벌어지는 앞니부위에서는 2.5 cm 폭경의 3.0 mm 두께의 단단한 치조점막이 관찰되었다. 전기메스로 전방부의 부착성 섬유밴드를 잘라준 후 즉각적인 개구정도는 16 mm 정도까지 가능하여 구강으로의 기관삽관이 가능하였다. 삽관후 양쪽 후방부 협측점막의 두꺼운 밴드들을 모두 제거하여 개구량을 33 mm까지 증진시킨 후 수술을 종결하였다. 환아의 보호자에게 거즈 블록과 설압자를 이용하여 개구 연습을 능동적으로 시키도록 강조하여 교육하였으며 술후 16개월 경과시까지 특별한 합병증이나 개구량 감소는 관찰되지 않았다. 독립적으로 발생한 선천성 치조점막 유합증 환자에서 비정상적으로 커져있는 과두와 설골이 관찰되었는데, 설-하악 구조의 비정상적인 발육에 기인하여 지속적인 비정상적 운동으로 인한 이차적인 치은과 협점막의 섬유성 부착이 생긴 것으로 추측되었다. 이에 마취과와의 효율적인 협진으로 기관절개술 등의 부가적인 마취방법 없이 효과적으로 치료할 수 있었다.

• Journal of Dental Rehabilitation and Applied Science
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• v.30 no.2
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• pp.192-198
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• 2014

This case is a porcelain laminate veneer (PLV) and all-ceramic crown treatment case on a female patient in her thirties who visited for esthetic improvement. The patient's chief complaint was protrusive and uneven anterior teeth, and she wanted minimum tooth reduction. The patient was in skeletal class II deep bite. Considering this, check bite method was used for mounting on articulator during diagnostic wax-up. Tooth reduction was done using mock-up base on diagnostic wax-up, and the amount of deletion was checked by index. For the accordance of shade, PLVs were restored in prior to all ceramic crown. After using all-ceramic crown, satisfactory esthetic improvement was obtained.

• Journal of Dental Rehabilitation and Applied Science
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• v.38 no.3
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• pp.162-170
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• 2022

In the case of patients with pathological tooth wear, it is necessary to evaluate the loss of the vertical dimension. Setting the appropriate vertical dimension is important to rehabilitate the patient's stable intermaxillary relationship. A 77-year-old female patient's chief complaint was the pain of the mandibular incisors and the lack of molars. At the first visit, pathologic tooth wear of the mandibular incisors were observed. After diagnosis and evaluation, loss of vertical dimension was not observed, but insufficient intermaxillary space for prosthetic restoration was confirmed. Mandibular rehabilitation was performed with vertical dimension increase and this showed satisfactory results both functionally and aesthetically.

• Journal of Practical Agriculture & Fisheries Research
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• v.18 no.1
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• pp.25-28
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• 2016

The welfare of horses depends on satisfying both the physiological and psychological needs of the animal. The object of this study was to evaluate fence safety at the horse farm. A Thoroughbred colt with cribbing was found dead in a paddock. The fence of paddock is a four-pipe fencing. He cribbed the 2nd pipe from the top. But he couldn't pull his face because his incisors acted as hooks and two ramuses of the mandible was entrapped in a top pipe. So he was embarrassed and went down while he terribly struggled to get out his face. Finally, he was strangulated to death. Safe fencing is essential on a horse farm. The function of these fences are to protect the horses but it was more of a hazard. In order to safe management of horses, facial length of the horse and the pipe interval of the fence should be considered. Further research is needed to put a muzzle on the horses while they are at a paddock. This study provides important benchmarks for the equine industry to consider fence type and evaluate fence safety.

• Applied Microscopy
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• v.38 no.4
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• pp.375-382
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• 2008

In order to investigate shape of synaptic vesicles of the tooth pulp afferent boutons and their presynaptic endings (p-endings), and the neuroactive substance of the p-endings in the trigeminal nucleus principalis, rat incisor tooth pulp afferents were labeled by the horseradish peroxidase (HRP) and quantitative ultrastructural analysis and postembedding immunogold labeling were performed. Labeled tooth pulp afferent boutons contained clear, spherical synaptic vesicles (diameter: $45{\sim}55\;nm$) and occasionally dense core vesicles(diameter: $80{\sim}120\;nm$). They formed symmetrical synapses with unlabeled axon terminals (p-endings) containing pleomorphic synaptic vesicles. The ratio of short to long diameter (form factor) of synaptic vesicles of pulp afferent boutons was 0.6 to 0.99, whereas that of p-endings was 0.25 to 0.99. In addition, most of the p-endings showed GABA-like immunoreactivity. These results indicate that the shape of synaptic vesicles is quite different between the tooth pulp afferent boutons and p-endings, and the p-endings may contain GABA as a neuroactive substance in the trigeminal nucleus principalis.