• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.3
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• pp.1-11
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• 2023

After the collapse of the Seongsu Bridge in the 1990s in Korea, attention was focused on the maintenance of facilities. The government has established various policies since the enactment of the Act in 1995 until recently. In general, safety inspections are performed to evaluate the safety grade of facilities, and facilities are maintained and managed by performing repairs and reinforcements for defects. However, since the budget is limited, it is impossible to carry out repair and reinforcement projects for all defects. It is necessary to prioritize repair and reinforcement measures. Then, the priority index (PI) is presented considering the importance of members, the seriousness of defects, and economic feasibility. In this index, the degree of influence can be adjusted within the range of 50 to 100% according to the expert's subjective judgment, and the same weight is set for some specific members. Also, the effect through repair and reinforcement is not taken into account decisively, and most of them have a limit in which priority is determined by economic feasibility. Therefore, in this study, through several case studies, problems with the priority index were reviewed and an equation was presented to improve them.

• Tuberculosis and Respiratory Diseases
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• v.44 no.4
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• pp.776-784
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• 1997

Background : Various combinations of treatment modalities have been reported in stage III non-small cell lung cancer (NSCLC). however, the standard treatment modality has not established yet. Recently, the efficacy of concurrent chemotherapy and radiation therapy has been reported in locally advanced lung cancer. We evaluate the response rate, toxicity, and survival of concurrent chemotherapy with etoposide and cisplatin(EP) and radiation therapy for unresectable stage III NSCLC. Method : Between October 1995 and December 1996, 32 patients with histologically proven unresectable stage III NSCLC without malignant pleural effusion were entered into this study. Twenty-nine patients were eligible for the response, survival, and toxicity analysis. Induction was two cycles of chemotherapy with etoposide and cisplatin plus concurrent chest RT to 4500cGy. Resection was attempted if the clinical response offered surgical resectability. Boost radiation therapy upto 5940cGy and one cycle of EP were performed if the disease were stable or responsive but still unresectable. Results : Of 29 eligible patients, 22(75.9%) showed partial response(PR). The progression free interval was 6.3months(range 1.1 to 19.5months). Surgical resection was performed in one patient. The median survival was 12.1months and one-year survival rate was 50.6%. The major toxicity was leukopenia($\geq$ grade 3, 46%). Thrombocytopenia over grade 3 was found in 11%. Radiation pneumonitis occurred in 13 patients(46%). Conclusion : Concurrent chemotherapy(EP) plus radiotherapy was effective and tolerable in the treatment of unresectable stage III NSCLC.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.20-29
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• 2018

Owing to the changing climate and recent flood events, flood damage caused by river levee collapse and overflow is on the rise in Korea, making it necessary to enhance river levee maintenance technologies to deal with various flood damage scenarios. This paper proposes the evaluation system of a river-levee safety map to improve maintenance efficiency and disaster responsiveness. A river-levee safety map, indicating sliding, piping, visual inspection, scouring, and safety index of a levee fill material on a GIS map will enable the dangerous zone to be identified visually and the development of proactive measures to deal with it. This will maximize the river-levee maintenance efficiency, which is a break from traditional practice in that restoration measures are taken only after the damage has occurred. This study includes scouring and levee fill material in addition to previously-proposed sliding, piping and visual inspections. The research activities conducted in the study include 1) categorization of scouring and levee fill material based on document and data examination, 2) evaluation of sliding and piping at 5 locations on the left levee in the Nam river according to the duration time of the flood water level, and 3) evaluation of the characteristics of scouring and levee fill material at 9 locations on the left/right levee in the Nam River. The river levee safety map proposed in this study would be more useful and practical but further study on the manual for river management organization, repair and reinforcement methods, and budget is required.

• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2000.09a
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• pp.155-161
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• 2000

It is very important to control the final load that acts on a support system, in tunnel engineering. A reliable analysis is needed to carry out technically reasonable design and safe construction. Also, a series of procedures of construction and the rock-support interaction behavior must be considered. Most existing studies have been performed as the limited analysis based on the simplified assumption. In this study, through the analysis of a circular tunnel using a 2-D finite differential code, the rook-support interaction behaviors in the variation of rock and stress conditions are analyzed and compared with the results from the closed form solutions. Consequently, more realistic rock-support interaction curves are obtained by including the effects of initial stresses and rock condition. These cures are very useful to predict the required support pressure in the initial design stage.

• Tunnel and Underground Space
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• v.10 no.3
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• pp.403-409
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• 2000

It is very important to control the final load that acts on a support system, in tunnel engineering. A reliable analysis is needed to carry out technically reasonable design and safe construction. Also, a series of procedures of construction and the rock-support interaction behavior must be considered. Most existing studies have been performed as the limited analysis based on the simplified assumption. In this study, through the analysis of a circular tunnel using a 2-D finite differential code, the rock-support interaction behaviors in the variation of rock and stress conditions are analyzed and compared with the results from the closed form solutions. Consequently, more realistic rock-support interaction curves are obtained by including the effects of initial stresses and rock condition. These curves are very useful to predict the required support pressure in the initial design stage.

• Journal of the Korean Society for Nondestructive Testing
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• v.23 no.1
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• pp.38-44
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• 2003

Performance demonstration with real flawed specimens has been strongly required for nondestructive evaluation of safety class components in nuclear power plant. Mechanical or thermal fatigue crack and intergranular stress corrosion cracking could be occured in the in-service nuclear power plant and mechanical fatigue crack was selected to study in this paper. Specimen was designed to produce mechanical fatigue flaw under tensile stress. The number of cycles and the level of stress were controlled to obtain the desired flaw roughness. After the accurate physical measurement of the flaw size and location, fracture surface was seal-welded in place to ensure the designed location and site. The remaining weld groove was then filled by using gas-tungsten are welding(GTAW) and flux-cored arc welding(FCAW). Results of radio graphic and ultrasonic testing showed that fatigue cracks were consistent with the designed size and location in the final specimens.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.6
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• pp.135-141
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• 2005

Currently many safety assessment tests are conducted by crashing a vehicle against a rigid or deformable barrier. It is quite rational to evaluate crash performance of a vehicle in a barrier test in terms of vehicle stiffness and strength. However, there has been a lot of debate on whether barrier testing is a duplicate of real world crash collisions. One of the issues is car to car compatability. There are two essential subjects in compatability. One is partner-protection when crashing into another vehicle and the other is self-protection when struck by another vehicle. When considering a car to car frontal crash between a mini car and a large heavy car, it is necessary to evaluate human body stiffness of each vehicle. In this study, in order to evaluate the compatability of cars in car-to-car crashes, four tests were conducted. Test speed of each car is 48.3km/h, and the overlap of the mini and large car is $40\%$, and the overlap of the small cars is $100\%$. In all tests, only a drive dummy is used. The test results of the car to car crash test show that vehicle safety standard of mini car is not satisfied compared with large heavy car and HIC value of mini car is higher than large car. In this case observed that the relatively lower stiffness and weight of the mini car resulted in absorbing a large share of the total input energy of the system when crashed into the large heavy car.

• Journal of the Korean Institute of Gas
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• v.7 no.1 s.18
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• pp.33-40
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• 2003

In this work, a novel approach was introduced to assess cost of loss resulting from risk as well as to help deciding inspection period through quantifying risk. In order to quantifying risk of city gas pipeline, frequency and consequence analysis were required. The main causes of city gas accident were analyzed to be digging, external corrosion, ground movement, and equipment failure. Tools to evaluate frequency of each cause was also suggested. Among city gas accidents, fire damage is the dominant one and mainly discussed; fatality, burning injury, and damage to building were estimated using the consequence model suggested. By combining frequency and consequence analysis, evaluating cost of risk management together with calculating example. This work could be applicable for city gas companies to plan how to manage risk most effectively.

• The Korea Journal of Herbology
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• v.32 no.4
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• pp.33-38
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• 2017

Objectives : Termitomyces albuminosus (Berk.) Heim is one of the famous wild edible mushrooms in the southern part of China. It is known that Termitomyces albuminosus, like Aconitum koreanum used in Korean traditional medicine, contains a kind of cerebroside, termitomycesphin, causing a pharmacologic effect on the neuron system. The pharmacologic effect of Termitomyces albuminosus can be used to possibly replace Aconitum koreanum. However, It needs to be certified as safe before it can be used. Here, a single-oral toxicity test and safety classification was conducted to obtain acute information of the toxicity of dried-Termitomyces albuminosus powder and to secure its safety in clinical applications. Methods : In order to calculate approximate lethal dose(ALD), test substance was orally administered to male and female SD-rat at dose levels of 5,000 and 0 (vehicle control) mg/kg (body weight). Based on the result of this toxicity, also the estimation of safety classification was calculated using the HED-based (human equivalent dose) MOS (margin of safety). Results : There were no mortalities, test substances treatment-related clinical signs, no changes in the body or organ weights, and no gross or histopathological findings at 14 days after treatment with test substance. Thus, the approximate lethal dose of dried-Termitomyces albuminosus powder was considered over 5,000 mg/kg in both female and male mice. Conclusions : Based on the limit dose, 5000 mg/kg, it was estimated that dried-Termitomyces albuminosus powder is classified as "Specified class B" indicating that clinical dose is not limited to patients as safe as food.

• The Korea Journal of Herbology
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• v.33 no.4
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• pp.53-58
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• 2018

Objectives : Kaempferia parviflora Rhizome is black ginger indigenous to Laos and Thailand. It has been used as a folk medicine to improve blood flow and promote vitality and longevity with good health and well being. For these reasons, Kaempferia parviflora Rhizome has been focused on developing it as a food or food supplement. In addition, Kaempferia parviflora Rhizome could be under consideration of new prescription based on its characteristic compounds, polymethoxyflavonoids. However, it needs to be certified as safe before it can be used. Here, a single-oral toxicity test and safety classification was carried out to identity acute information of the toxicity of Kaempferia parviflora Rhizome powder and to make sure of its safety in clinical applications. Methods : Test substance was orally administered to male and female SD-rat at dose levels of 5000 mg/kg to estimate approximate lethal dose(ALD). Based on the acute information of the toxicity, the safety classification was estimated using the HED(human equivalent dose)-based MOS(margin of safety). Results : At 14 days after treatment with test substance. there were no of test substance related with mortalities and clinical signs. In addition, no changes in the body or organ weights and no gross or histopathological findings were observed. Thus, the ALD of Kaempferia parviflora Rhizome powder was considered over 5,000 mg/kg in both female and male mice. Conclusions : Based on the single oral toxicity test using the highest and limit dose, 5,000 mg/kg and the decision guideline for safety classification based on HED-based MOS, it was estimated that Kaempferia parviflora Rhizome powder is classified as "Specified class B" indicating that clinical dose is not limited to patients as safe as food.