• Title/Summary/Keyword: 안전관리기준

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Current research trends of analytical methods for non-nutritive sweeteners (Non-nutritive sweeteners 분석을 위한 최근 분석기술 동향)

  • Yun, Choong-In;Kim, Young-Jun
    • Food Science and Industry
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    • v.55 no.1
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    • pp.58-73
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    • 2022
  • Due to the recent demand for low-calorie foods, consumers are looking for alternative sweeteners that can control blood sugar, low risk of tooth decay and low calories. Regulations for permitted sweeteners in food vary from every country, and it is important for the government and the food industry to monitor products containing these sweeteners to ensure global compliance. Therefore, rapid, precise, and accurate analysis for food matrices should be applied to quality control, market surveillance, monitoring, and evaluation of food additive intake in the food industry. To analyze sweeteners simultaneously, it is essential to develop an efficient and rapid analytical method and to perform appropriate pretreatment steps such as solvent extraction and purification. This study presented the recent analysis trends about the suitable extraction method for food matrices focusing on non-nutritive sweeteners. Additionally, techniques for multi-compounds analysis using HPLC and LC-MS/MS and non-destructive analysis techniques using FT-IR were comprehensively described.

Legal Issues for the Implementation of Non-Face-to-Face Treatment (비대면진료 실행을 위한 법적 쟁점)

  • Kwon, Ohtak
    • The Korean Society of Law and Medicine
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    • v.23 no.3
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    • pp.47-87
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    • 2022
  • Due to the COVID-19 pandemic, non-face-to-face treatment was temporarily permitted. A lot of consensus has been formed on the need to continuous non-face-to-face treatment. However, the current 「Medical Service Act」 only permits telemedicine between doctors and medical personnel. On the other hand, as a result of legal interpretation, there is an opinion that non-face-to-face treatment is allowed. But considering the overall legal system, non-face-to-face treatment is not allowed. Nevertheless, we have to consider the reality such as the development of science and technology and the outbreak of infectious diseases. Therefore, it is not advisable to allow face-to-face treatment only. Ultimately, it is necessary to find ways to ensure that non-foce-to-face treatment can be performed in a safe and effective manner. And it should be institutionalized. This is strategically necessary and important. Therefore, we must look over ahead legal issues to be discussed. First of all, the scope, the target disease and the subject of implement have to be clear. Also, structurally, the standards of facilities and equipment must be prepared for non-face-to-face treatment to be implemented. Functionally, communication and information exchange between doctors and patients should be well conducted. In addition, the information protection management system that occurs in the process of non-face-to-face treatment should be materialized. Lastly, the issue of responsibility and cost of non-face-to-face treatment should be decided in detail. When these problems materialize, it can be expected that a safe non-face-to-face treatment environment will be established.

Acoustic outputs from clinical ballistic extracorporeal shock wave therapeutic devices (임상에서 사용중인 탄도형 체외충격파 치료기의 음향 출력)

  • Cho, Jin Sik;Kwon, Oh Bin;Jeon, Sung Joung;Lee, Min Young;Kim, Jong Min;Choi, Min Joo
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.5
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    • pp.570-588
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    • 2022
  • We scrutinized the acoustic outputs from the 70 shock wave generators of the 15 product models whose technical documents were available, among the 46 ballistic extracorporeal shock wave therapeutic devices of 11 domestic and 6 foreign manufacturers, approved by the Minster of Food & Drug Safety (Rep. Korea). We found that the acoustic Energy Flux Density (EFD), the most popular exposure parameter, was different by up to 563.64 times among shock wave generators at their minimum output settings and by up to 74.62 times at their maximum settings. In the same product model, the EFD was shown to vary depending on shock wave transmitters by up to 81.82 times at its minimum output setting and by up to 46.15 times at its maximum setting. The lowest EFD 0.013 mJ/mm2 at the maximum output settings was much lower (2.1 %) than the maximum value 0.62 mJ/mm2 at the minimum settings. The Large acoustic output differences (tens to hundreds of times)from the therapeutic devices approved for the same clinical indications imply that their therapeutic efficacy & safety may not be assured. The findings suggest the regulatory authority to revise her guideline to give clearer criteria for clinical approval and equality in performance, and recommend the authority to initiate a post-approval surveillance as well as a test in conformance between the data in technical documents and the real acoustic outputs clinically used.

A Study on Digital Documentation of Precise Monitoring for Microscale Displacements within the Tomb of King Muryeong and the Royal Tombs in Gongju, Korea (공주 무령왕릉과 왕릉원 내부 미세변위 정밀모니터링을 위한 디지털 기록화 연구)

  • Choi, Il Kyu;Yang, Hye Ri;Lee, Chan Hee
    • Journal of Conservation Science
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    • v.37 no.6
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    • pp.626-637
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    • 2021
  • The tomb complex of the royal family from the period of the Ungjin Baekje Kingdom (475 to 538 AD) in Gongju, Korea, contains the tomb of King Muryeong and other royal tombs. After the excavation of the tomb of King Muryeong in 1971, these tombs were opened up to the public, without the establishment of systems for their safety, conservation and management. The tombs have consequently experienced rapid environmental changes and suffered various damages. In this study, specific vulnerable parts inside the tombs were selected for deviation analysis using 3D scanning, and 3D image models were constructed on this basis. Progressive displacement was identified in tomb No. 5, and basic data for future investigations was acquired from tomb No. 6 and the tomb of King Muryeong. In the deviation analysis for the southern plastered wall of tomb No. 5, the damage was not found to exceed the ranges of ±18 mm and ±2 mm. However, the lintel stone was found to be sagging by 0.32 mm on average, and the distance between the walls to have increased by 0.36 mm on average. Direct water seepage occurring in tomb No. 5 is considered to be increasing the damage within the tomb, such as the dropping and sagging of the lintel. The 3D image models constructed in this study will play an important role as baseline data for future research, and can be used to discuss a secure conservation scheme for the tombs through cross-validation with precise measurement monitoring.

Impact of the coastal structures on the water circulation near Gusipo coast, Yellow Sea, Korea (서해 구시포 해안에서 해수유동에 미치는 구조물의 영향)

  • Kim, Cha-Kyum;Park, Il Heum
    • Journal of Korea Water Resources Association
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    • v.55 no.11
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    • pp.865-875
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    • 2022
  • Field measurements and numerical simulations using EFDC model were performed to quantify the changes of water circulation near Gusipo coast located in the Yellow Sea of Korea to estimate the impact of the construction of the coastal structures (jetty, groin, Gusipo port and bridge). The model predicted tide and tidal currents agreed reasonably well with the measurements. The maximum currents during spring tide near the Gusipo Beach (GB) have the range of 20~40 cm/sec whereas those off the GB range from 60 to 80 cm/sec. The typical patterns of tidal current show parallel with the local isobath. Tidal currents flow northeastward during the flood tide whereas the currents during the ebb tide flow southwestward. The current speeds at shielded waters after the construction of coastal structures strongly decreased as compared with those before the construction. The tidal volume due to the construction of coastal structures was estimated using the depth averaged velocity for 24 hours of spring tide. Tidal volume after construction of coastal structures was compared with initial state (before construction). Tidal volume at present state (after construction of jetty, groin, Gusipo port and bridge) decreased by 28.4% as compared with that of the initial state. The volume after construction of jetty and groin decreased by 21.3%, and the volume after construction of Gusipo port and bridge decreased by 9.8%.

Reliable Assessment of Rainfall-Induced Slope Instability (강우로 인한 사면의 불안정성에 대한 신뢰성 있는 평가)

  • Kim, Yun-Ki;Choi, Jung-Chan;Lee, Seung-Rae;Seong, Joo-Hyun
    • Journal of the Korean Geotechnical Society
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    • v.25 no.5
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    • pp.53-64
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    • 2009
  • Many slope failures are induced by rainfall infiltration. A lot of recent researches are therefore focused on rainfall-induced slope instability and the rainfall infiltration is recognized as the important triggering factor. The rainfall infiltrates into the soil slope and makes the matric suction lost in the slope and even the positive pore water pressure develops near the surface of the slope. They decrease the resisting shear strength. In Korea, a few public institutions suggested conservative slope design guidelines that assume a fully saturated soil condition. However, this assumption is irrelevant and sometimes soil properties are misused in the slope design method to fulfill the requirement. In this study, a more relevant slope stability evaluation method is suggested to take into account the real rainfall infiltration phenomenon. Unsaturated soil properties such as shear strength, soil-water characteristic curve and permeability for Korean weathered soils were obtained by laboratory tests and also estimated by artificial neural network models. For real-time assessment of slope instability, failure warning criteria of slope based on deterministic and probabilistic analyses were introduced to complement uncertainties of field measurement data. The slope stability evaluation technique can be combined with field measurement data of important factors, such as matric suction and water content, to develop an early warning system for probably unstable slopes due to the rainfall.

Thermo-hydraulic Numerical Analysis for the Leakage of Buried District Heating Pipe (열수송관의 누수에 대한 열-수리적 수치해석)

  • Shin, Hosung;Hong, Seung-Seo
    • Journal of the Korean Geotechnical Society
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    • v.38 no.3
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    • pp.17-26
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    • 2022
  • Domestic district heating system needs safety management guidelines using the change of surface temperature to detect damages to buried heat pipes. This paper performed numerical analyses on the temperature change of ground surface due to the burial and leakage of heat pipes. Temperature difference between the ground surface above the buried heat pipes and the surrounding surface rises to a crescendo between 3 am and 8 am. It is more significant in winter rather than in summer. Low groundwater level magnifies the temperature increase of the ground surface by the heat pipe, which is smaller in the asphalt pavement than in the bare soil. Without leakage of the buried heat pipe, the temperature increment on the ground surface by the heat pipe is within 3.0℃ in the bare soil and 3.5℃ in the asphalt pavement. Leakage of the supply heat pipe in the bare soil increases the temperature on the ground surface gradually in the summer but rapidly in the winter. Asphalt pavement shows a lower increment and increasing rate of the temperature on the ground surface due to pipe leakage than bare soil surface. And leakage on both sides of the supply pipe takes 1-2 days for the temperature difference from the surrounding soil surface to reach 10℃.

Development of Functional Halogenated Phenylpyrrole Derivatives (기능성 할로겐화 페닐피롤 )

  • Min-Hee Jung;Hee Jeong Kong;Young-Ok Kim;Jin-Ho Lee
    • Journal of Life Science
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    • v.33 no.10
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    • pp.842-850
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    • 2023
  • Pyrrolnitrin, pyrrolomycin, and pyoluteorin are functional halogenated phenylpyrrole derivatives (HPDs) derived from microorganisms with diverse antimicrobial activities. Pyrrolnitrin is a secondary metabolite produced from L-tryptophan through four-step reactions in Pseudomonas fluorescens, Burkholderia cepacia, Serratia plymuthica, etc. It is currently used for the treatment of superficial dermatophytic fungal infections, has high antagonistic activities against soil-borne and foliar fungal infections, and has many industrial applications. Since pyrrolnitrin is easily decomposed by light, it is difficult to widely use it outdoors. As an alternative, fludioxonil, a synthetically produced non-systemic surface fungicide that is structurally similar and has excellent light stability, has been commercialized for seed and foliar treatment of plants. However, due to its high toxicity to aquatic organisms and adverse effects in human cell lines, many countries have established maximum residue levels and strictly control its levels. Pyrrolomycin and pyoluteorin, which have antibiotic/antibiofilm activity against Gram-positive bacteria and high anti-oomycete activity against the plant pathogen Pythium ultimum, respectively, were isolated and identified from microorganisms. This review summarizes the biosynthesis and production of natural pyrrolnitrin derived from bacteria and the characteristics of synthetic fludioxonil and other natural phenylpyrrole derivatives among the HPDs. We expect that a plethora of highly effective, novel HPDs that are safe for humans and environments will be developed through the generation of an HPD library by microbial biosynthesis and chemical synthesis.

Learning from the Licensing and Training Requirements of the USA Private Security Industry : focused on the Private Security Officer Employment Authorization Act & California System (미국의 민간경비 자격 및 교육훈련 제도에 관한 연구 - 민간경비원고용인가법(PSOEAA) 및 캘리포니아 주(州) 제도 중심으로 -)

  • Lee, Seong-Ki;Kim, Hak-Kyong
    • Korean Security Journal
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    • no.33
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    • pp.197-228
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    • 2012
  • The private security industry in Korea has rapidly proliferated. While the industry has grown quickly, though, private security officers have recently been implicated in incidents involving violence, demonstrating an urgent need for systematic reform and regulation of private security practices in Korea. Due to its quasi-public service character, the industry also risks losing the public's favor if it is not quickly disciplined and brought under legitimate government regulation: the industry needs professional standards for conduct and qualification for employment of security officers. This paper shares insights for the reform of the Korean private security industry through a study of the licensing and training requirements for private security businesses in the United States, mainly focusing on the Private Security Officer Employment Authorization Act (hereinafter the PSOEAA) and the California system. According to the PSOEAA, aspiring security officers shall submit to a criminal background check (a check of the applicants' criminal records). Applicants' criminal records should include not only felony convictions but also any other moral turpitude offenses (involving dishonesty, false statement, and information on pending cases). The PSOEAA also allows businesses to do background checks of their employees every twelve months, enabling the employers to make sure that their employees remain qualified for their security jobs during their employment. It also must be mentioned that the state of California, for effective management of its private security sector, has established a professional government authority, the Bureau of Security and Investigative Services, a tacit recognition that the private security industry needs to be thoroughly, professionally, and actively managed by a professional government authority. The American system provides a workable model for the Korean private security industry. First, this paper argues that the Korean private security industry should implement a more strict criminal background check system similar to that required by the PSOEAA. Second, it recommends that an independent professional government authority be established to oversee and enforce regulation of Korea's private security industry. Finally, this article suggests that education and training course be implemented to provide both diverse training as well as specialization and phasing.

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Asbestos Exposure and Health Risk Assessment for the Residents Near the Abandoned Mining Area in Chungbuk, Korea (충북지역 폐석면광산 인근주민의 석면노출과 건강위해도 평가)

  • Shin, Jin-Ho;Oh, Seok-Ryul;Hwang, Soon-Yong;Chung, Sook-Nye;Kim, Ji-Hui;Nam, Eun-Jung;Lee, Jin-Hyo;Choi, Hee-Jin;Eom, Seok-Won;Chae, Young-Zoo;Park, Chul-Hwi
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.5
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    • pp.345-350
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    • 2012
  • To investigate the exposure and health risk assessment for the residents near the D-asbestos mine in Chungbuk, Korea. We analyzed asbestos in the 20 ambient air and 23 activity based samples near the mine. The airborne sample results are showed that 8 of 20 samples ranged between 0.0025 to 0.0029 f/cc (fiber per cubic centimeter) and the others were below the detection limit by phase contrast microscopy (PCM). In addition, asbestos fibers were under the detection limit or not being by transmission electron microscopy (TEM). Based on interview and survey targeting the local residents, we made the activity based sampling (ABS) scenarios fit to the conditions of field. At the same time, we calculated the excess lifetime cancer risk (ELCR) of these ABS scenarios according to the ELCR average value and 95% upper confidence limit (UCL). At the case of weed whacking, soil digging and sweeping yard scenario, 95% UCL of ELCR exceeded the $1{\times}10^{-4}$, acceptable risk range for exposure. Based on our study results, it is necessary safety measures such as risk communication, abatement or management of naturally occurring asbestos (NOA).