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Effect of Alcohol Detoxification Beverage that Contained Bulnesia sarmienti on Alcohol-metabolizing Enzymes and Antioxidant Enzyme Activities (Bulnesia sarmienti 를 함유한 숙취해소 음료가 알코올대사 및 항산화 효소활성에 미치는 영향)

  • Lim, Ae-Kyung;Jung, Mee-Jung;Lee, Jae-Wook;Hong, Joo-Heon;Kim, Kil-Soo;Jung, Seok-Bang;Kim, Dae-Ik
    • Food Science and Preservation
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    • v.18 no.3
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    • pp.407-413
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    • 2011
  • This study was carried out to investigate the effect of a beverage that contained Bulnesia sarmienti(BSP, 2.5%) on rats to which alcohol was administered. The treatment of the BSP group reduced the serum alcohol concentration to 52%, compared to 47% in the positive control(PC) group. Similar pattell1s were observed in the enhancement of alcohol dehydrogenase(ADH), acetaldehyde dehydrogenase(ALDH), alkaline phosphate(ALP), alanine aminotransferase(ALT), asparate aminotransferase(AST), total cholesterol(CHOL), ${\gamma}$-glutamyltrasferase(GGT), glucose(GLU), total bilirubin, and total protein(TP) in the serum. Also, in the BSP group, the lipoxidase(LPO), glutathion-S-transferase(GST), XO, catalase(CAT), and superoxide dismutase(SOD) were significantly reduced, compared to the CO and PC groups in the liver. The glutathione(GSH) activity increased in the BSP group, though. These results indicate that Bulnesia sarmienti extract can enhance alcohol metabolization activity.

A Phantom Study for the Optimal Low-dose Protocol in Chest Computed Tomography Examination (흉부 전산화단층촬영검사를 위한 최적의 저선량 프로토콜에 관한 팬텀연구)

  • Kim, Young-Keun;Yang, Sook;Wang, Tae-uk;Kim, Eun-Hye
    • Journal of radiological science and technology
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    • v.44 no.2
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    • pp.101-107
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    • 2021
  • The purpose of this study was to evaluate optimal CT scan parameters to minimize patient dose to the irradiation and maintain satisfactory image quality in low-dose chest computed tomography (CT) scans. In a chest anthropomorphic phantom, chest CT scans were performed at different kVp and mA within reference of 3.4mGy in volume CT Dose Index (CTDIvol). The following quantitative parameters had been statistically evaluated: image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and figure of merit (FOM). Nine radiographers conducted the blind test to select the optimal kVp-mA combination. Results indicated that the kVp-mA combination of 80kVp-90mA, 100kVp-50mA, 120kVp-30mA and 140kVp-30mA were obtained high SNR and CNR. The 120kVp-30mA combination offered good compromise in the FOM, which showed the quality and dose performance. In the blind test, an image of 80kVp-90mA obtained a high score with 4.7 points, and 120kVp-10mA or 140kVp-10mA with a low tube current were observed severe noise and poor image quality, thus resulting in decreased diagnostic accuracy. On the other hand, in the combination of high kVp and high mA(140kVp-90mA), the image quality was improved, but the radiation dose was also increased. the FOM value of 140kVp-90mA was lower than 120kVp-30mA. The application of appropriate scan parameters in low-dose chest CT scans produced satisfactory results in dose and image quality for the accuracy of the clinical diagnosis.

A Study on the Distribution of Microorganisms in Department of Radiography (영상의학과 촬영실의 미생물 분포에 관한 연구)

  • Chang, Jeong-Hyun;Yang, Eun-Ju;Kim, Young-Jae
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.165-171
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    • 2021
  • To prevent the secondary hospital-acquired infection (cross-infection) from occurring in the general radiographic room in the department of radiology, the microbial measurement was conducted at the points making direct close contact with radiologists and patients. For the case of radiologists, the microbial measurement and incubation were focused on the x-ray tube handle of the radiation generating device, and, for the case of patients, the microbial measurement and incubation were focused on the chin supporting device, chest-contact point, and handle. Once disinfected with Aniosurf, the sterilized media were gathered and identified, and the microorganisms were confirmed. Based on the identification results, it was confirmed that the points making direct close contact with radiologists showed a value of 103 CFU for Proteus mirabilis, Staphylococcus epidermidis, Bacillus spp. and Candida spp., and that the points making direct close contact with patients showed a value of 103~5 CFU for Proteus mirabilis, Enterococcu faecium, Pseudomonas aeruginosa, NTM(Non-Tuberculosis Mycobacteria) and Candida spp.. It was also confirmed that the types and number of microorganisms gathered from the points making direct close contact with patients were greater. Fortunately, most of the involved microorganisms were observed to be on the skin surface and are known to become extinct when disinfected in accordance with the hospital-acquired infection control rules. However, since even minor exposure to such microorganisms may be lethal for patients with reduced immunity, caution must be taken. In particular, since the points making contact with patients showed a high level of microbial measurement, it was thought that it would be necessary for radiologists and personnel having frequent access to strictly disinfect the parts, such as instruments and handles, making frequent contact with patients. The purpose of this study was to announce the importance of safe microbial control in the radiographic inspection room in hospital, and this study is expected to be used as the baseline data for preventing hospital-acquired secondary infection and Nth infectious diseases.

The Rapid Detection of Pathogens in Organically Grown Vegetables Using PCR-DGGE (PCR-DGGE를 이용한 유기농 채소의 유해 미생물 신속 검지)

  • Kwon, Oh Yeoun;Son, Seok Min
    • Food Engineering Progress
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    • v.15 no.4
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    • pp.370-375
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    • 2011
  • In this study the polymerase chain reaction (PCR) combined with denaturing gradient gel electrophoresis (DGGE) was evaluated as a method permitting the rapid detection of pathogens in fresh originally grown vegetables. A universal primer (341GCf/534r) was selected for its ability to amplify the V3 region of 16S-rRNA genes in their target pathogens (Salmonella typhimurium, Pseudomonas fluorescens, Bacillus cereus, Listeria monoytogenes, Staphyloocus aureus, E. coli). The 194 bp fragments in PCR were successfully duplicated as expected. The amplified fragments of the same size from six different pathogens also showed good separation upon DGGE. The detection limit of PCR-DGGE for six pathogens in fresh-cut lettuces were over $10^{5}$ CFU/g when sampled by stomaching. However, when the sampling method was changed from stomaching to shaking, the detection limit of six pathogens in organic vegetables was shown to increase by over $10^{1}$ CFU/g, but only those of B. cereus were over $10^{3}$ CFU/g. Therefore, PCR-DGGE was shown to be a reliable method for the detection of pathogens in fresh-cut vegetables.

Convergence Study on Sterilized Dental Instruments Expiration Date (멸균된 치과기구의 유효기간에 관한 융합연구)

  • Na, Jae-Gyeong;Park, Hae-Ryeon;Sung, Hye-Lin;Song, In-Ha;Joo, Jung-Hwan;Kang, Kyung-hee
    • Journal of the Korea Convergence Society
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    • v.9 no.12
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    • pp.129-135
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    • 2018
  • This study aimed to investigate the contamination rate of microorganisms by times after sterilization in mirrors, dental explorers, and pincettes which are the basic tools used in the dental clinic. 60 samples by each tool were used upon packaging them by 10 units. Contamination rate of microorganisms were tested using dry film media(3M Petrifilm Plates) which is a quick check upon collecting 10 samples right after sterilization, at Week 2, 3, 4, 5, and 6. At Week 0 when was right after sterilization, no microorganism was detected in any tools while they were detected in 2 mirrors, 2 dental explorers, and 2 pincettes at Week 6. 2 to 4 colonies on average were detected in mirrors at Week 2 and 4, 1 to 2 colonies in explorers from Week 5, and no colony was found in pincettes until Week 5 but 1 to 2 colonies at Week 6. Based on these results, the needs of effective periods are suggested for the sterilized tools together with their safe usages.

Emergency angioembolization performed in a hemodynamically unstable patient with grade V liver injury: The benefit of emergency angioembolization without computed tomography (혈역학적으로 불안정한 grade V 간손상에서 시행한 응급 혈관색전술: 전산화단층 촬영 없이 시행한 응급 혈관색전술의 이점)

  • Kang, Wu Seong;Park, Chan Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.235-239
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    • 2019
  • High-grade liver injury is associated with high morbidity and mortality rates. We report successful emergency angioembolization and early interventional radiology support to manage a high-grade liver injury in a 29-year-old man who presented following a fall during parachute training. Upon arrival, his blood pressure was 80/40 mmHg, and emergency ultrasonography showed a liver injury with perihepatic fluid collection. The patient's blood pressure reduced to 60/40 mmHg, and emergency angiography was performed without computed tomography (CT) (door to puncture time 36 min). After angioembolization, his blood pressure returned to 120/77 mmHg. Subsequent CT revealed no additional bleeding or hollow viscus injury. He was admitted to the Intensive Care Unit and discharged without complications 30 days after admission. In this case, emergency angioembolization (without performing CT) could successfully and safely treat a hemodynamically unstable patient with a high-grade liver injury.

System Software Design of Computed Tomography Radiation Dose Management (컴퓨터 단층촬영(CT) 방사선 노출 관리 시스템 소프트웨어 설계)

  • Yang, Yu-mi;Lee, Kil-hung;Cho, Sang-wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2014.05a
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    • pp.489-492
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    • 2014
  • This thesis provides the design of system software for the management of radiation dose that is generated using computer tomography(CT). Because radiation exposure is different depending on the difference in sensitivity to each part for each of the patient's body, if we will be able to manage an appropriate amount of radiation, it is possible to estimate the radiation exposure of the patient as a result. Recently, radiation leakage incident of Japanese nuclear power plant was in the news internationally and there is a growing interest not only a nuclear power plant, to medical radiation exposure. In spite of the fact that currently safety management of radiation is under control only the workers of the radiation involved, exposure management of patients until now have been required. Surgery and inspection using the radiation in Korea will increase, due to this medical exposure has increased, but it is a reality that medical institution don't know the level of radiation exposure applied to the patient. Therefore a system for managing the radiation exposure of the patient from the medical institution is required. This paper proposes a design of a software program to manage the radiation exposure of CT is an typical imaging tool to use the radiation in the medical institution. By check the amount of radiation dose and set the limit of dose, we would help to optimize the medical exposure of the patient.

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Development of an open source-based APT attack prevention Chrome extension (오픈소스 기반 APT 공격 예방 Chrome extension 개발)

  • Kim, Heeeun;Shon, Taeshik;Kim, Duwon;Han, Gwangseok;Seong, JiHoon
    • Journal of Platform Technology
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    • v.9 no.3
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    • pp.3-17
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    • 2021
  • Advanced persistent threat (APT) attacks are attacks aimed at a particular entity as a set of latent and persistent computer hacking processes. These APT attacks are usually carried out through various methods, including spam mail and disguised banner advertising. The same name is also used for files, since most of them are distributed via spam mail disguised as invoices, shipment documents, and purchase orders. In addition, such Infostealer attacks were the most frequently discovered malicious code in the first week of February 2021. CDR is a 'Content Disarm & Reconstruction' technology that can prevent the risk of malware infection by removing potential security threats from files and recombining them into safe files. Gartner, a global IT advisory organization, recommends CDR as a solution to attacks in the form of attachments. There is a program using CDR techniques released as open source is called 'Dangerzone'. The program supports the extension of most document files, but does not support the extension of HWP files that are widely used in Korea. In addition, Gmail blocks malicious URLs first, but it does not block malicious URLs in mail systems such as Naver and Daum, so malicious URLs can be easily distributed. Based on this problem, we developed a 'Dangerzone' program that supports the HWP extension to prevent APT attacks, and a Chrome extension that performs URL checking in Naver and Daum mail and blocking banner ads.

Accuracy Analysis for Slope Movement Characterization by comparing the Data from Real-time Measurement Device and 3D Model Value with Drone based Photogrammetry (도로비탈면 상시계측 실측치와 드론 사진측량에 의한 3D 모델값의 정확도 비교분석)

  • CHO, Han-Kwang;CHANG, Ki-Tae;HONG, Seong-Jin;HONG, Goo-Pyo;KIM, Sang-Hwan;KWON, Se-Ho
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.4
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    • pp.234-252
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    • 2020
  • This paper is to verify the effectiveness of 'Hybrid Disaster Management Strategy' that integrates 'RTM(Real-time Monitoring) based On-line' and 'UAV based Off-line' system. For landslide prone area where sensors were installed, the conventional way of risk management so far has entirely relied on RTM data collected from the field through the instrumentation devices. But it's not enough due to the limitation of'Pin-point sensor'which tend to provide with only the localized information where sensors have stayed fixed. It lacks, therefore, the whole picture to be grasped. In this paper, utilizing 'Digital Photogrammetry Software Pix4D', the possibility of inference for the deformation of ungauged area has been reviewed. For this purpose, actual measurement data from RTM were compared with the estimated value from 3D point cloud outcome by UAV, and the consequent results has shown very accurate in terms of RMSE.

Quality Control of Dose Calibrator using 3D Printery (3D 프린터를 이용한 Dose Calibrator의 품질관리)

  • Ryu, Chan-Ju
    • Journal of the Korean Society of Radiology
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    • v.15 no.3
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    • pp.307-312
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    • 2021
  • In nuclear medicine, radioactive isotope tracers are administered to the human body to obtain and evaluate disease morphological information and biological function information. Dose calibrator is a device used to measure the radioactivity of a single nuclide in medical institutions. Administration of the correct dose to the human body acts as an important factor in diagnosis and treatment, and measurement through a dose calibrator before administration is the most important factor. Dose calibrator performs daily quality control after installation in each medical institution. Quality control is a means of guaranteeing quality control after installation, and is essential for improving the quality of treatment and promoting patient safety. Therefore, accurate and standardized performance evaluation methods should be established. In this study, 3D printing was used for quantitative evaluation of quality control by increasing the accuracy and standardization of quality control. When the 3D printer was installed and reproducibility was tested, the error range of the expected value and reading value decreased by 0.302% in the F-18 nuclide and 0.09% in the 99mTc-pertechnate nuclide than when the 3D printer was installed. The error rate for other nuclides was also found to have a low error rate for reproducibility tests when 3D printing was installed.