• Proceedings of the Korean Information Science Society Conference
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• 2000.04b
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• pp.469-471
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• 2000

본 논문에서는 모멘트 항을 추가한 수정된 kernel-adatron 알고리즘을 제안하고 이른 support vector machines의 학습기법으로 이용하였다. 이는 기울기상승법에서 일어나는 최적해로의 수렴에 따른 발진을 억제하여 그 수렴 속도를 좀더 개선시키는 모멘트의 장점과 kernel-adatron 알고리즘의 구현용이성을 그대로 살리기 위함이다. 제안된 학습기법의 SVM을 실제 200명의 암환자를 2부류(초기와 악성)로 분류하여 문제에 적용하여 시뮬레이션한 결과, Cambell등의 kernel-adatron 알고리즘을 이용한 SVM의 결과와 비교할 때 학습시간과 시험 데이터의 분류률에서 더욱 우수한 성능이 있음을 확인할 수 있었다.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.6
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• pp.456-463
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• 2008

Purpose: We evaluated the incidence and malignant risk of focal breast lesions incidentally detected by $^{18}F-FDG$ PET/CT. Various PET/CT findings of the breast lesions were also analyzed to improve the differentiation between benign from malignant focal breast lesions. Materials & Methods: The subjects were 3,768 consecutive $^{18}F-FDG$ PET/CT exams performed in adult females without a history of breast cancer. A focal breast lesion was defined as a focal $^{18}F-FDG$ uptake or a focal nodular lesion on CT image irrespective of $^{18}F-FDG$ uptake in the breasts. The maximum SUV and CT pattern of focal breast lesions were evaluated, and were compared with final diagnosis. Results: The incidence of focal breast lesions on PET/CT in adult female subjects was 1.4% (58 lesions in 53 subjects). In finally confirmed 53 lesions of 48 subjects, 11 lesions of 8 subjects (20.8%) were proven to be malignant. When the PET/CT patterns suggesting benignancy (maximum attenuation value>75 HU or <30HU; standard deviation of mean attenuation > 20) were added as diagnostic criteria of PET/CT to differentiate benign from malignant breast lesions along with maximum SUV, the area under ROC curve of PET/CT was significantly increased compared with maximum SUV alone ($0.680{\pm}0.093$ vs. $0.786{\pm}0.076$, p<0.05). Conclusion: The malignant risk of focal breast lesions incidentally found on $^{18}F-FDG$ PET/CT is not low, deserving further diagnostic confirmation. Image interpretation considering both $^{18}F-FDG$ uptake and PET/CT pattern may be helpful to improve the differentiation from malignant and benign focal breast lesion.

• Proceedings of the KAIS Fall Conference
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• 2010.05b
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• pp.663-666
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• 2010

이 논문에서는 우리나라 사망원인의 1위인 악성신생물 중에서 2000년부터 가장 빈도가 높은 폐암에 대하여 우리나라와 OECD 국가들 간에 사망률과 잠재수명손실연수(PYLL)에 통계학적으로 차이기 있는가를 살펴보아서 폐암에 대한 국가 간 비교와 폐암 사망구조의 문제점을 파악하여 보건정책, 보건교육, 보건자원배분 등에 자료를 제공코자 한다.

• Journal of Digestive Cancer Research
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• v.9 no.1
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• pp.19-24
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• 2021

The incidence of small and asymptomatic pancreatic neuroendocrine neoplasms (PNENs) has been increased due to the widespread use of high-resolution imaging techniques and endoscopic procedures in screening programmes. Most of PNENs are indolent neoplasms with slow-growing. However, sometimes, PNENs show local invasion or metastasis with poor prognosis. The management of small, nonfunctioning PNENs remain under debate. The National Comprehensive Cancer Network guidelines recommend observation in selected cases of small PNENs less than 2 cm. Pancreatic surgeons are divided into two factions: "the hawks," who indicate the high risk of malignancy even in small PNENs and, therefore, the need for an aggressive surgical treatment, and the "the doves," who accepts the risk of malignancy in some ≤ 2 cm PNENs, advocate that the risk of overtreating many benign ≤ 2 cm PNENs would be much higher. As the pancreatic surgery remains a high-risk operation with a 28-30% morbidity and 1% mortality, the decision for small PNENs is challenging.

• Journal of Gastric Cancer
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• v.9 no.1
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• pp.1-5
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• 2009

In the past, conservative bypass surgery was usually performed for palliation of malignant obstruction of the gastrointestinal tract. However, endoscopic stenting was developed recently, and technical advances and clinical experience have made it possible to establish stent implantation as one of the main treatment options. There are several advantages in stent implantation over bypass surgery, such as high feasibility and technical success rate, non-invasiveness, rapid symptomatic response, short hospitalization, and cost-effect benefits. Complications, such as stent ingrowth, stent injury by bile or acid, and migration, may occur and early re-insertion is frequently needed. Recently, diverse novel stents which are powered to predict stent migration or ingrowth have been developed and are being used in the clinical setting. In general, stent implantation is known to be beneficial in patients who are expected to survive <6 months, and surgical bypass may be more effective in patients who can survive >6 months. In this review, we have compared the technical feasibility, clinical outcomes, complications, and cost-benefit between stent implantation and bypass surgery, and determined the optimal treatment strategy in malignant upper gastrointestinal obstruction.

• The Journal of Dong Guk Oriental Medicine
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• v.6 no.2
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• pp.109-133
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• 1998

In these days, the outbreak rate of a malignant tumor is gradually increasing, and the frequency digestive organ's cancer is so high that the remedy is being studied in the Oriental Medicine World. I made a consideration the Erlgyuk, the Panwue(反胃), the Juckchui(積聚), the Jangdok(臟毒), on the symptom and treatment of gastrointestinal cancer, with the successsive literatures of the Myung and Chung Dynasty. In consequence, these are similar to the symptom of malignant tumor in abdominal cabity, and the treatment is divided into three stages each period. The Geosa-method(祛邪法) is used in the early stage, and in the middle the Gongbokyumsi-method(攻補兼施), and in the latter stage the Pujung-method(扶正法) is used. The successive literatures shows the prescription of gastrointestinal cancer in variety. Therefore, I think the various prescription will be applied to gastrointestinal cancer on forward.

• Childhood Kidney Diseases
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• v.7 no.2
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• pp.229-233
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• 2003

Mortality and morbidity of malignant hyperthermia has decreased markedly by the avoidance of succinylcholine, and the earlier detection and introduction of dantrolene. We report a fourteen-year-old boy who developed malignant hyperthermia during general anesthesia. He showed the earlier clinical signs, such as elevation of end-tidal $CO_2$, tachycardia, and hypertension. After prompt administration of dantrolene, operation was continued with profopol and midazolam. Rhabdomyolysis and myoglobinuria followed, and were managed by hydration and alkalinization of urine. Azotemia did not occur, and he was discharged without any sequelae on the $10^{th}$ postoperative day.

• Korea journal of population studies
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• v.8 no.1
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• pp.139-170
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• 1985

사망원인통계연보는 사망발생 당년에 신고된 사망 자료만 수록하고 있는데, 본 연구에서는 사망원인통계연보에 수록된 사망(당년신고, 또는 비지연신고)은 물론 수록되지 아니한 사망(지연신고)의 사인구조를 파악하고자 한다. 부차적으로, 사인구조를 평가하기 위해서 지연신고의 다양한 특성을 검토하고 있다. 1983년부터 1993년까지 신고된 모든 사망신고를 기초로, 지연신고와 당년신고라는 신고행태에 따라 사인별 사망구성비, 사망률, 사망률성비를 구하였다. 지연신고율이 지속적으로 감소하고 있지만, 지연신고율은 다른 집단보다 여성, 젊은층, 의사진단사망자, 병원사망자에게서 더 높다. 당년신고 사망자의 성별 사인구조와 비교해 볼 때, 지연신고 사망자의 주요 사인구조는 성별에 따라 달라지는데, 남성에게는 감염성질환, 순환기계질환, 호흡기계질환의 비중이 더 커지고, 여성에게는 감염성질환, 호흡기계질환 및 소화기계질환의 비중이 더 커진다. 1983~1993년 동안 신고된 모든 사망에 대한 주요 발견은 다음과 같다. 첫째, 순환기계질환, 악성 종양, 손상 및 중독이 남녀 모두에게 주요 3대 사인이다. 둘째, 만성 간질환, 각종 사고, 폐암, 자살은 남성에게 치명적인 사인으로서 남녀의 성별 사망력 차이를 넓혀주는 원인이다. 세째, 손상 및 중독, 특히 교통사고는 45세 이하의 젊은 층에게 중요한 사인이 되는데 반해, 순환기계질환, 악성 종양, 소화기계질환은 고령층에게 중요한 사인이 된다.

• Radiation Oncology Journal
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• v.28 no.2
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• pp.111-116
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• 2010

Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.

• Journal of Advanced Navigation Technology
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• v.14 no.6
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• pp.838-844
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• 2010

This paper introduces Stuxnet, a malicious ware that presently stimulates severity of the cyber warfare worldwide, analyses how it propagates and what it affects if infected and proposes a process to cure infected systems according to its organization. Malicious wares such as Stuxnet secretes themselves within the system during propagation and it is required to analyze file hiding techniques they use to detect and remove them. According to the result of the analysis in this paper, Stuxnet uses the library hooking technique and the file system filter driver technique on both user level and kernel level, respectively, to hide its files. Therefore, this paper shows the results of the Stuxnet's file hiding approach and proposes an idea for countermeasure to neutralize it. A pilot implementation of the idea afterward shows that the stealthing techniques of Stuxnet are removed by the implementation.