• Food Science and Preservation
• /
• v.19 no.5
• /
• pp.792-798
• /
• 2012

The purpose of this study was to evaluate the anti-atopic-dermatitis effect of Angelica keiskei extract using a DNFB-induced animal model of atopic-dermatitis symptoms. A. keiskei was prepared via extraction with DW, 50% ethanol, and 100% ethanol in addition to fresh juice. All the extracts reduced the thickness levels of the ears and ear epidermis against swelling by DNFB inducement, especially in the aqueous-extract-treated group. The mRNA expressions of matrix metalloproteinases (MMPs), however, were not observed, which may indicate that Angelica keiskei extract alleviates the atopic-dermatitis symptoms in an MMP-independent manner. Finally, the level of the inflammatory cytokine IL-4 was inhibited only in the juice-treated group, although the IL-13 level was inhibited in the juice-, 50%-ethanol-extract-, and 100%-ethanol-extract-treated groups in a dose-dependent manner, and was not inhibited in the aqueous-extract-treated group. Taken together, these results suggest that Angelica keiskei extract has an inhibitory effect on atopic dermatitis, and may be a useful biomaterial for the development of cosmeceuticals.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.49 no.2
• /
• pp.180-187
• /
• 2022

The aim of this study was to investigate the risk factors associated with sleep disordered breathing (SDB) by comparing intraoral factors, body mass index (BMI), and medical history with pediatric sleep questionnaire (PSQ) findings. Seven hundred eighty-seven subjects aged between 7 to 11 years old were included. Their caregivers were asked to complete questionnaires. Oral manifestations including Angle's classification, overjet, and Brodsky tonsil grade were examined. Children with PSQ scores of more than 0.33 points were classified into the SDB high-risk group. Among the 787 subjects, 34 (4.3%) were classified into the SDB high-risk group. Children with allergic rhinitis, atopic dermatitis, excessive overjet, or large tonsil size had a significantly higher risk for SDB versus those without. Also, there was a significant difference in SDB risk according to BMI status. Gender, gestational age, breastfeeding, and Angle's classification were not associated with SDB. Children at high risk for SDB were predisposed to tonsillar hypertrophy, allergic rhinitis, obesity, and atopic dermatitis. Children with these factors could be candidates for early intervention to prevent the progression of SDB.

• Journal of Industrial Convergence
• /
• v.18 no.5
• /
• pp.70-76
• /
• 2020

The purpose of this study was to determine the dietary behavior of adolescents and to determine the association with allergic diseases according to dietary behavior. The data were obtained from the 15th Korea Youth Risk Behavior Survey 2019. Complex-sample descriptive statistics and the chi-square test were used for data analysis in SPSS. Adolescents diagnosed with asthma had a relationship with frequency of breakfast, fruit, soda, energy drink, sweet drink, fast food, vegetable and convenience store eating experience. Adolescents diagnosed with allergic rhinitis were associated with frequency of breakfast, fruit, soda, sweet drinks, vegetables, and milk. Adolescents diagnosed with atopic dermatitis were associated with soda, vegetables, milk, and convenience store eating experiences. Therefore, in the case of adolescents with allergic diseases, it is necessary to educate them on correct dietary behavior so that they can have correct habits.

• The Journal of Pediatrics of Korean Medicine
• /
• v.17 no.1
• /
• pp.71-86
• /
• 2003

Objectives : The aim of this study was to investigate the classification methods of the external treatments of atopic dermatitis for Children. Methods: We surveyed the oriental medical book concerning the atopic dermatitis for Children. Results : 1. The oriental herbal medications for the atopic dermatitis used with Ryuhwang(硫?), WoongHwang(雄黃), KyoungBun(輕粉), WhangBaek(黃栢), SeokGo(石膏) and so on. 2. The frequently used type of external prescription is solid or liquid. 3. The external preparations were frequently painted or washing with to the lesion of dermatitis. For the wet type of atopic dermatitis, the solid prescription were sprinkled on the lesion or irrigated with the liquid. For the dry type, the mixed prescription of the solid and liquid were painted on the lesion.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.20 no.2 s.33
• /
• pp.247-255
• /
• 2007

Objective : Atopic dermatitis is a chronic, inflammatory skin disease which was characterized by intense pruritus and the course marked by exacerbation and remission. The purpose of this study is to report the effect of oriental treatment. Especially new oriental prescription to atopic dermatitis Methods : We treated children patients who had atopic dermatitis and visited oriental hospital of Semyung University. Children patients in this case are two person. The first one is fourteen-years-old female, Other one is seven-years-old boy. And I create a new oriental prescription that named 'Allergy 1' thinking about oriental theory. After then I treated them with 'Allergy 1' herb medication and used two index to assess the severity in atopic dermatitis. Results : Each index show us approximately 70% improvement in atopic dermatitis symptom. Conclusion : On the basis of this cases, It may be considered that treatment of atopic dermatitis should be improved by the treatment of herb medication "Allergy 1"

• Journal of Haehwa Medicine
• /
• v.17 no.2
• /
• pp.185-198
• /
• 2008

Wished to examine closely effect that Atopy cream-Jawoongo ointment (A-J) used to atopy dermatitis disease patient get in atopy eruption control experimentally. In this research A-J ointment as treatment result to a NC/Nga mouse by BMAC ointment, clinical skin severity score decreased remarkably than control group. Thus, NC/Nga mice suffered from dermatitis very similar to human AD with IgE hyperproduction. Specially, result that measure IgE and IgG1 level in serum decreased remarkably than control group.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.17 no.3
• /
• pp.80-87
• /
• 2004

Objectives : Ceramic based intra-red Therapy has been effective on dermatitis and immune system. The purpose of this study was to know the clinical effect of ceramic based infra-red therapy on Atopic Dermatitis(AD). Methods: For 3 months from Dec. 2003 to Feb. 2004, we treated ceramic based intra-red therapy to 21 outpatients with AD who visited Hana Oriental hospital. Ceramic based infra-red therapy using GI-2000 system was lighted to undressed outpatients for 15 minutes, three times a week. Results and Conclusions: Ceramic based intra-red therapy showed useful effect on AD, especially itching sign.

• Korean Journal of Veterinary Research
• /
• v.45 no.3
• /
• pp.439-444
• /
• 2005

A 7.1 kg, seven-year old, castrated male, Shih-Tzu with severe pruritus, chronic otitis externa and Malassezia infection was referred to Veterinary Medical Teaching Hospital of Chungnam National University. In local animal hospital, steroid therapy was used to treat uncontrollable pruritus, but the clinical signs were recurrent when steroid therapy was discontinued. On physical examination, generalized alopecia, erythema, papules, severe crust and diffuse lichenification were presented. Tape strip test of skin lesions revealed cocci and Malassezia infections. Based on the result of history, clinical signs and examination described above, canine atopic dermatitis with secondary superficial pyoderma and Malassezia dermatitis was diagnosed. Oral challenge with cyclosporine and antibiotics had good results in clinical signs. Clinical sign scores were evaluated by investigator with CADESI at 2weeks, 4weeks, 6weeks, 8weeks and 10weeks after cyclosporine administration. And in the result of comparing of allergen-specific IgE value, the level of allergen-specific IgE to general causative allergen after 10 weeks of cyclosporine therapy was higher than that before cyclosporine therapy.

• The Korean Chronic Disease News
• /
• no.312
• /
• pp.1-18
• /
• 2007

서울 마포구 보건소 하현성 소장/65세 이상 서울시민 무료 치매 검진/‘건강투자’보건의료전략 제시/국산약 해외진출,“ 현지화가 급선무”/‘의약품정책협의회’공식 출범/서방형 성장호르몬 상품화 성공/“다 함께 건강증진, 안전한 마포 건설”/지역자원역량강화 통합적 서비스 체계 구축/전립선비대증‘녹차’예방 효과 커/건강검진 수검자 비만율 30.64%/“식품첨가물, 아토피피부염과 상관없다”/허리둘레 크면 당뇨위험 2.2배 증가/발의 구조가 무너지면 인체의 구조가 무너진다/고령친화 모델지역 기본구상/

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.10 no.11
• /
• pp.3500-3505
• /
• 2009

Sixteen moderate atopic dermatitis patients were treated with applying toner and cream using estern medical herbs[Estern medical complex(Radix Glycyrrhizae, Radix Angelicae Dahuricae, Rhizoma Ligustici Chuanxiong, Fructus ponciri Seu Aurantii Immaturus, Radix Rehmanniae Praeparata, Radix Puerariae, Rhizoma Corydalis), Cypress, Green tea, Radix Astragali, Red ginseng, Syrup ferment, Apple ferment filtrate] on the atopic area 2-3 times per day for 6 weeks. After 6 weeks of study, the result was a decrease in SCORAD index($26.9{\pm}11.8$ to $14.9{\pm}9.7$(p<0.05)), IgE($641.9{\pm}1294.6$ to $565.8{\pm}1076.8$), Eosinophil count($246.7{\pm}203.5$ to $203.3{\pm}130.7$(p<0.05)) and TEWL($16.7{\pm}5.1$ to $15.4{\pm}8.7$(p<0.05)). And skin hydration was increased($36.6{\pm}10.0$ to $44.0{\pm}10.3$(p<0.01)) maintaining skin pH level. The patient;s and physician's global assessment also improved. Therefore, estern medical herbs may play a role in treatment of atopic dermatitis.