• The Journal of Bigdata
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• v.6 no.2
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• pp.161-168
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• 2021

In this study, we propose a cardiovascular disease prediction model using machine learning. First, a multidimensional analysis of various differences between the two groups is performed and the results are visualized. In particular, we propose a predictive model using cost-sensitive learning that can improve the sensitivity for cases where there is a high class imbalance between the normal and patient groups, such as diseases. In this study, a predictive model is developed using CART and XGBoost, which are representative machine learning technologies, and prediction and performance are compared for cardiovascular disease patient data. According to the study results, CART showed higher accuracy and specificity than XGBoost, and the accuracy was about 70% to 74%.

• The Journal of the Convergence on Culture Technology
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• v.8 no.4
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• pp.339-345
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• 2022

Cardiovascular diseases is one of the leading causes of death in the world. The objectives of this study were to build various models using sociodemographic variables based on three variable selection methods and seven machine learning algorithms for the identification of hypertension and dyslipidemia and to evaluate predictive powers of the models. In experiments based on full variables and correlation-based feature subset selection methods, our results showed that performance of models using naive Bayes was better than those of models using other machine learning algorithms in both two diseases. In wrapper-based feature subset selection method, performance of models using logistic regression was higher than those of models using other algorithms. Our finding may provide basic data for public health and machine learning fields.

• 순환기질환의공학회:학술대회논문집
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• 2003.11a
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• pp.10-11
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• 2003

• 대한예방의학회:학술대회논문집
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• 1999.10a
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• pp.198-199
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• 1999

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.542-546
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• 2008

In this study, we developed a whole cardiovascular system model combined with a Laplace heart based on the numerical cardiac cell model and a detailed arterial network structure. The present model incorporates the Laplace heart model and pulmonary model using the lumped parameter model with the distributed arterial system model. The Laplace heart plays a role of the pump consisted of the atrium and ventricle. We applied a cellular contraction model modulated by calcium concentration and action potential in the single cell. The numerical arterial model is based upon a numerical solution of the one-dimensional momentum equations and continuity equation of flow and vessel wall motion in a geometrically accurate branching network of the arterial system including energy losses at bifurcations. For validation of the present method, the computed pressure waves are compared with the existing experimental observations. Using the cell-system-arterial network combined model, the pathophysiological events from cells to arterial network are delineated.

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.712-714
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• 2017

미병의 예방과 관리의 중요성이 거론되고 있으나, 미병에 대한 분류나 진단을 위한 확고한 근거가 미약한 상황으로서 미병 진단 인자 분류를 위한 생리시스템 모델 개발이 필요한 시점이다. 본 연구의 목적은 개발한 생리학적 모델이 미병 단계를 구별하는데 효과 및 유용성이 있는지를 임상 검증하기 위하여 생리학적 모델 인공지능 시뮬레이션을 개발하고자 함이다. 인공지능 계산은 3층으로 구성된 네트워크를 이용하였으며 각 층은 30개의 neuron들로 구성하였다. 인공지능망의 입력 값은 나이, 수축기 혈압, 이완기 혈압, 심박수 값 (입력 값 4개)이고 출력 값은 혈관 저항값인 Ra이다. 머신러닝 차수를 높이면서 인공지능을 사용하지 않은 생리적 모델로부터 도출된 결과와 인공지능을 통하여 계산된 결과를 비교하였다. 개발된 인공지능계산을 이용한 생리시스템 모델은 대량의 표본집단에서 임상 검증에 기여할 것이다.

• Journal of the Korea Computer Graphics Society
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• v.23 no.1
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• pp.49-55
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• 2017

Computed tomographic angiography (CTA) is widely used in the diagnosis and treatment of coronary artery disease because it shows not only the whole anatomical structure of the cardiovascular three-dimensionally but also provides information on the lesion and type of plaque. However, due to the large size of the image, there is a limitation in manually extracting coronary arteries, and related researches are performed to automatically extract coronary arteries accurately. As the coronary artery originate from the ascending aorta, the ascending aorta and ostium should be detected to extract the coronary tree accurately. In this paper, we propose an automatic segmentation for the ostium as a starting structure of coronary artery in CTA. First, the region of the ascending aorta is initially detected by using Hough circle transform based on the relative position and size of the ascending aorta. Second, the volume of interest is defined to reduce the search range based on the initial area. Third, the refined ascending aorta is segmented by using a two-dimensional geodesic active contour. Finally, the two ostia are detected within the region of the refined ascending aorta. For the evaluation of our method, we measured the Euclidean distance between the result and the ground truths annotated manually by medical experts in 20 CTA images. The experimental results showed that the ostia were accurately detected.

• Journal of the Korea Society of Computer and Information
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• v.27 no.5
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• pp.21-28
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• 2022

All health problems that occur in the circulatory system are refer to cardiovascular illness, such as heart and vascular diseases. Deaths from cardiovascular disorders are recorded one third of in total deaths in 2019 worldwide, and the number of deaths continues to rise. Therefore, if it is possible to predict diseases that has high mortality rate with patient's data and AI system, they would enable them to be detected and be treated in advance. In this study, models are produced to predict heart disease, which is one of the cardiovascular diseases, and compare the performance of models with Accuracy, Precision, and Recall, with description of the way of improving the performance of the Decision Tree(Decision Tree, KNN (K-Nearest Neighbor), SVM (Support Vector Machine), and DNN (Deep Neural Network) are used in this study.). Experiments were conducted using scikit-learn, Keras, and TensorFlow libraries using Python as Jupyter Notebook in macOS Big Sur. As a result of comparing the performance of the models, the Decision Tree demonstrates the highest performance, thus, it is recommended to use the Decision Tree in this study.

• Journal of the Korean Society of Radiology
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• v.15 no.5
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• pp.691-696
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• 2021

In order to prevent and treat a patient's disease, the anatomical structure of the lesion through medical imaging is one of the important processes. However, there is a limit to the image displayed on the screen, so many studies are underway to overcome this by using 3D printing technology. To this end, this study implemented a three-dimensional cardiovascular model using actual patient image data, printed it out using a 3D printer, and conducted a usefulness test on current medical professionals. As a result of the usefulness evaluation, when the questionnaire conducted by a total of 5 people was converted to the Likert scale, the average value of all items showed a high result of 4.83 points, and the result of the cross-analysis was (P) = 10.000 (0.265), which was equally positive among all the questionnaires survey results were presented. Based on the results, it is expected that 3D printing technology will help advance medical technology.

• Journal of Biomedical Engineering Research
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• v.42 no.3
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• pp.100-106
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• 2021

Measuring Intima-media thickness (IMT) with ultrasound images can help early detection of coronary artery disease. As a result, numerous machine learning studies have been conducted to measure IMT. However, most of these studies require several steps of pre-treatment to extract the boundary, and some require manual intervention, so they are not suitable for on-site treatment in urgent situations. in this paper, we propose to use deep learning networks U-Net, Attention U-Net, and Pretrained U-Net to automatically segment the intima-media complex. This study also applied the HE, HS, and CLAHE preprocessing technique to wireless portable ultrasound diagnostic device images. As a result, The average dice coefficient of HE applied Models is 71% and CLAHE applied Models is 70%, while the HS applied Models have improved as 72% dice coefficient. Among them, Pretrained U-Net showed the highest performance with an average of 74%. When comparing this with the mean value of IMT measured by Conventional wired ultrasound equipment, the highest correlation coefficient value was shown in the HS applied pretrained U-Net.