• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2001.05a
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• pp.162-168
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• 2001

성인의 정서에 따른 심혈관계 반응의 변화에 대한 연구는 많이 있으나, 아동 정서에 따른 심혈관계 반응에 대한 연구는 거의 없는 실정이다. 본 연구에서는 본 연구실에서 개발한 자극을 이용하여 유발된 정서에 따른 심혈관계 반응의 차이를 규명하고자 한다. 복합자극으로 구성된 아동용 정서유발 프로토콜을 사용하여 아동에게 다섯가지 정서(기쁨, 슬픔, 분노, 스트레스, 무료함)를 유발시키는 동안 심혈관계 반응(ECG, PPG)을 측정하였다. 실험참여 아동은 만 5세에서 9세 사이의 아동으로 모두 141명이며, 분석에는 132명 (학령전 남: 30/ 학령전 여: 33/ 학령후 남:37, 학령후 여:32)의 데이터가 활용되었다. 분석에 사용하나 심혈관계 생리반응 변수는 심박률(HR), 호흡주기 관련 심박률변화 (RSA), 심박률분산(HRV), 심박률분산의 고주파수성분 (HFHRV)과 저주파수성분 (LF HRV), 혈류량 (FPV)이었다. 이 변수들 중 심박률, R파 간 간격을 기준으로 한 심박률변산의 고주파수 성분과 저주파수 성분, 그리고 혈류량에서 정서에 따라 유의미한 차이가 나타났다. 심박률은 기쁨, 슬픔을 스트레스나 무료함과 구분할 수 있고, 분노를 다른 정서들과 구분하는 것으로 나타났다. 혈류량 역시 분노와 다른 정서들 간에 유의미한 차이를 보였다. 고주파수 성분은 무료함을 나머지 정서들과, 저주파수 성분은 슬픔, 스트레스를 무료함과 구별할 수 있었다. 정서에 따라서는, 기쁨과 분노 유발정서에서는 심박률과 혈류량이 감소하였고, 슬픔은 심박률과 저주파수성분이 감소하였으며, 스트레스는 독특하게 심박률이 감소하였다. 그리고 무료함에서는 고주파수성분과 저주파수성분은 증가하고 혈류량은 감소하는 특징적인 양상을 보였다. 결론적으로 본 연구는 심혈관계 반응을 이용하여 아동정서를 구분하는 것이 가능함을 밝혔다.공을 제외한 BH-2, BH-3호공에서의 이방성 투수량계수텐서값은 이 논문의 가정인 대수층이 이방성이고 균질하다는 가정에 일치하지 않았다. 따라서 원형좌표계에 도시하였을 때 다른 공에 비해서 비균질성이 심한 결과로 인해 이방성타원체 에서 많이 벗어남을 보였다. 이로인해 3개의 공 BH-1, BH-4, BH-5호공을 사용하여 대수층의 이방성을 분석하여 보았다. BH-1호공에서의 $T_{{\varepsilon}{\varepsilon}}$는 171.90 $m^2$/day, $T_{ηη}$는 71.0l $m^2$/day이고 주 텐서방향은 Nl5.39$^{\circ}$ E로 나타났다. BH-4호공의 $T_{{\varepsilon}{\varepsilon}}$는 268.20 $m^2$/day, $T_{ηη}$는 28.75 $m^2$/day이고 주 텐서방향은 N7.55$^{\circ}$E이며 BH-5호공에서의 $T_{{\varepsilon}{\varepsilon}}$는 168.40 $m^2$/day, $T_{ηη}$는 66.80 $m^2$/day이고 주 텐서방향은 N76.59$^{\circ}$E로 나타났다. 이처럼 연구지역에서의 각각의 공에 대한 투수량계수텐서는 서로 다르게 나타났으며 이에 따른 주 텐서방향도 서로 다름을 알 수 있다.. Targeting a 10% recycling rate for municipal waste in 2001. EPA plans to research and develop new rec

• Science of Emotion and Sensibility
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• v.12 no.3
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• pp.317-324
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• 2009

The aim of this study was to determine whether or not cardiovascular reactivity parameters serve as good indicators in identifying differential emotion in children. The study particularly focused on five emotions(i.e., happiness, sadness, anger, stress, and boredom), thus, study participants were introduced to a combination of music, color, stories, and dolls to induce complex emotions. During the experiment, corresponding cardiovascular reactivity in response to the conditioned stimuli were recorded on physiological parameters including HR, RSA, HRV, HF HRV, LF HRV, and FPV. After the cardiovascular reactivity responses were measured, participants rated on the types and intensity of emotions they had experienced during the emotional stimuli exposure. Results on psychological response show that four emotions except for stress were appropriately and effectively induced participants by emotional stimuli. Findings of physiological responses suggest that, except for RSA, all of the physiological indicators show significant differences among five emotions. This indicates that children' emotions can be measured and differentiated by cardiovascular reactivity, or in other words, emotion specific responses have the ability to distinguish different emotions in children.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.416.2-417
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• 2004

심혈관계 질환(CVD, Cardiovascular disease, CHD, Coronary heart disease)은 심장의 관상동맥에 염증반응과 혈전으로 인해 죽상경화중이 생겨 관상동맥이 좁아지거나 막히는 결과를 초래하는 질환으로 관상동맥질환, 고혈압, 말초혈관질환, 협심증, 심근경색증, 중풍 등이 포함된다. 심혈관계 질환의 위험인자들에는 서구화된 식생활, 유전, 나이, 성, 고혈압, 당뇨, 고지혈증, 비만, 운동부족, 스트레스, 흡연, 가족력 등이 있다. 그러나 식생활의 변화로 인한 심혈관계 질환과 생화학적 지표의 변화 및 관련 기전에 대한 연구는 거의 없었다.(중략)

• Proceedings of the KOSOMBE Conference
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• v.1995 no.05
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• pp.190-194
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• 1995

체성-교감 반사 유발시 동맥혈압의 조절에 관여한다고 생각되는 상부 복외측 연수 내의 심혈관계 세포를 대상으로 흥분발사의 반응특성을 측정, 분석하였다. 심장 박동주기와 시간적으로 동기되는 흥분발사를 보이는 심혈관계 세포를 찾은 후 체성-교감 반사의 승압반응과 감압반응을 유발시키며 각각에 대해 동일한 세포의 흥분발사의 변화를 측정한 결과 5가지 유형의 반응특성을 얻을 수 있었다. 이들 간에 구성되어 있는 회로망 연결을 설명하고자 2 가지 종류의 특성 세포와 적절한 자극 전달 경로 및 세포간 회로망 연결을 도입하여 본 연구의 실험결과를 모두 설명할 수 있는 가장 간단한 죄소 세포회로망 모델을 구성하였다. 최소 모델의 고찰 결과 고유한 감압경로의 존재가능성이 도출되었다.

• The Korean Journal of Pharmacology
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• v.30 no.3
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• pp.313-319
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• 1994

This study was undertaken to investigate the relationship between the $Na^+$ channels of the cardiovascular regulation center and the responses to increased $Na^+$ concentration in the cerebrospinal fluid (CSF), by observing the effects of icv administration of the agents affecting $Na^+$ transport. Icv infusion of $200\;{\mu}l$ of 1 M NaCl produced hypertension and bradycardia in the urethane-anesthetized rabbit, and the bradycardia was inhibited and reversed to tachycardia by vagotomy. Amiloride, a $Na^+$ transport inhibitor, produced hypertension and bradycardia, which were not altered by vagotomy, and it did not affect the NaCl-induced responses. Benzamil, a derivative of amiloride with higher specificity, neither produced any cardiovascular effects by itself, nor affected the NaCl-induced responses. In vagotomized rabbits, icv amiloride reversed the NaCl-induced tachycardia to a bradycardia, but the bradycardiac effect was not altered by pretreating with NaCl. This study showed that although amiloride and benzamil slightly differ in their cardiovascular action, neither of them did affect the NaCl-induced responses. We suggest that the $Na^+$ channels which are sensitive to amiloride or benzamil in the cardiovascular regulation center are not involved in the NaCl-induced response.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.1021-1024
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• 2010

고령 남성들의 건강관리 및 처치를 위한 복합 운동 프로그램 참여에 따른 혈관 염증 반응에 미치는 효과를 규명하고자 하였다. 따라서 WBC에 있어서, 운동집단은 프로그램 참여 전에 비해 참여 후에 유의하게 감소된 반면, 통제 집단은 각 변인들에서 증가되거나 악화되는 결과를 보였다. CRP에 있어서, 운동집단은 프로그램 참여 전에 비해 참여 후에 유의하게 감소된 반면, 통제 집단은 각 변인들에서 증가되거나 악화되는 결과를 보였고, RF는 두 집단 모두 차이가 없었다. 따라서 심혈관계 질환을 보유한 고령자들이라도 건강관리 측면에서 체계적인 신체활동에 적극적으로 참여 한다면, 염증 질환의 유지보다는 향상의 결과를 가져올 수 있으며, 차후 세부적인 연구가 필요하지만, 고령자들의 신체활동은 혈관의 탄력을 향상시키고, 급성 염증 반응에 의한 심혈관계 질환 합병증을 예방하고 보다 긍정적인 향상의 효과를 가져 올 수 있다.

• Sleep Medicine and Psychophysiology
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• v.7 no.2
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• pp.109-114
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• 2000

Objectives: This study was performed to examine the characteristic cardiovascular response patterns associated with the imagination and discussion of anger-provoked events in patients with hwa-byung. Methods: Forty-three female patients with hwa-byung were evaluated with the Korean version of the State-Trait Anger Expression Inventory, the State-Trait Anxiety Inventory, Hamilton Rating Scale for Anxiety, Beck Depression Inventory, and Hamilton Rating Scale for Depression just before the task. Subjective Units of Distress (SUDS) and Vividness of the event (VIVID) during the imagination and discussion of the event were evaluated immediately after tasks. Blood pressure (BP) and heart rate (HR) during baseline, rest, and tasks were also evaluated. Results: Both startle and recovery responses of BP, startle response of HR, SUDS, and VIVID in discussion task were significantly larger than in the imagination task. Conclusion: Results suggest that it is undesirable for the patients to excessively and repeatedly recall and talk about the anger events.

• Exercise Science
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• v.21 no.1
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• pp.111-120
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• 2012

The purpose of the study was to assess the effects of different cardiorespiratory fitness response to exercise training on cardiovascular disease and adipocytokine release and gene expression in abdominal obesity women. forty eight middle-age women were divided to a exercise-responder (n=34) group (ERG) and a exercise-nonresponder (n=14) group (ENRG) based on cardiorespiratory fitness after exercise training (12weeks, 1200 kcal/week, moderate-vigorous intensity, walking and jogging). Cardiorespiratory fitness was measured using maximal oxygen uptake with metabolic gas analysis and body composition was determined by bioelectrical impedance. We measured lipid and glucose profiles, blood adipocytokines and adipocytokine genes expression in adipose tissue. Waist girth (p=0.040), and %body fat (p=0.031) were significantly decreased in ERG than ENRG. Triglyceride (p=0.023) and systolic blood pressure (0.046) were significantly decreased in ERG than ENRG. Blood leptin (p=0.022) was significantly decrease in ERG than ENRG but leptin gene expression was decreased both groups (p<0.001). These results show that exercise-responder group improved cardiovascular disease risk factors and adipocytokine more than exercise-nonresponder group after exercise training. Moreover, exercise-nonresponders group show that obese indices and blood leptin and leptin gene expression in adipose tissue were decreased despite the failure to improve fitness. Therefore, regular exercise training seems to give health benefits although the failure to improve fitness.

• Journal of Biomedical Engineering Research
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• v.22 no.5
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• pp.393-402
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• 2001

A computational model representative of cardiovascular circulation was built using 12 standard lumped compartments. Especially, both the baroreceptor reflex and the cardiopulmonary reflex control model were implemented to explain the auto-regulation of cardiovascular system. Another important aspect of this model is to utilize the impulse-response curve of the nerve system in transferring the impulse error signals to autonomous nerve system. For the verification of this model, we have computed the normal hemodynamic conditions and compared those with the clinical data. Then. hemodynamic shock of 20% hemorrhage to cardiovascular system was simulated to test the effects of the control system model. The results of these two simulations were well matched with the experimental ones. The steady state LBNP simulation was also performed. The transient changes of hemodynamic variables due to ramp increase of bias pressure of LBNP showed good agreement with the physiological experiments. Numerical solution using only the baroreflex model showed relatively a larger deviation from the experimental data. compared with the one using the control model haying both the baroreflex and the cardiopulmonary reflex systems, which shows an important role of the cardiopulmonary reflex system for the simulation of the hemodynamic behavior of the cardiovascular system .

• Journal of Life Science
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• v.22 no.4
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• pp.532-537
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• 2012

We investigated the effect of smoking on cardiovascular responses during acute dynamic exercise. Eleven college students who had been smoking (duration of smoking: $7.45{\pm}0.90$ years; number of cigarettes per day: $17.72{\pm}1.22$) participated in this study. All subjects completed a graded exercise testing to determine the relative exercise intensity. The cardiovascular responses were measured at rest, and during mild and moderate exercise immediately, 24, and 48 hours after smoking. The same procedures were repeated during 24-h smoking withdrawal. All subjects were continuously instrumented to measure systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV), cardiac output (CO), and total vascular conductance (TVC) at rest and during exercise. The results showed that compared to the nicotine abstention, SBP, DBP, MAP, and HR were significantly higher at 24 and 48 hours after smoking ($p$<0.05), and CO was significantly higher at rest and during moderate exercise ($p$<0.05). There were no differences in SV and TVC before and after smoking. Thus, the results suggest that smoking is associated with an exaggerated sympathetic nerve activity during dynamic exercise. Consequently, smoking cessation may help reduce cardiac events, such as stroke and heart attack, during exercise.