• The Korean Journal of Nuclear Medicine
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• v.28 no.3
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• pp.371-376
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• 1994

To reevaluate the clinical usefulness of erection penography for diffential diagnosis of impotence, we reviewed retrospectively the data of penography in 56 patients who were diagnosed as impotence by various diagnostic workup. Twelve normal males were studied as control group. Papaverine HCl 30mg was injected into the corpus cavernosum and simultaneously $^{99m}Tc$-HSA 20mCi was injected via an antecubital vein. After injection radioactivities in the penile area were detected for 30 minutes by gamma camera and time activity curve was displayed. We defined that transit time(TT) is the time to reach peak activity and erection persistent time(EPT) is the duration of time to maintain peak activity and venous index(VI) is the ratio of radioactivity($R_{30}/R_{max}$). The results were as follows. The TT of arteriogenic group($10.7{\pm}2.8min$) was significantly increased compared with those of control and venogenic groups(P<0.05, respectively). The EPT of venogenic group ($6.2{\pm}6.8min$) is significantly decreased compared with those of control and arteriogenic groups(P<0.05, respectively). The TT of psychogenic($15.2{\pm}5.5min$) is significantly increased compared with those of control and arteriogenic groups(P<0.05, respectively). In conclusion erection penography was very useful for the diagnosis of vascular and psychogenic impotence and for differentiation between arteriogenic and venogenic but it could not differentiate mixed type or neurogenic from vascular or psychogenic.

• 건강소식
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• v.25 no.11 s.276
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• pp.16-17
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• 2001

• The Monthly Diabetes
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• s.209
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• pp.19-24
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• 2007

당뇨병에 성기능장애가 많다는 것은 옛날부터 알려져 있지만 실제로는 그릇된 지식과 선입관에 의해 과장되게 잘못알고 있는 경우가 많다. 당뇨병이라고 모두 발기부전 환자는 아닌 것이며 정상 건강인보다 조금 높은 빈도를 보이는 것뿐이다. 식사요법과 운동요법으로 혈당조절을 잘하고 합병증을 예방하면 정상인과 다름없는 성생활을 할 수 있으며 인슐린 치료를 계속하면서 주의 깊게 혈당을 조절하고 합병증을 예방하면 60세 이후까지도 정상적인 성생활이 가능하다. 정상인도 노쇠하면 자연현상으로 언젠가는 모두 발기부전이 되므로 당뇨병환자만이 발기부전이 오는 것은 아니므로 미리 겁내고 불안해할 필요는 없는 것이다. 당뇨병환자중에는 선입관에 의해 당뇨라는 진단을 받고 정신적 충격과 그릇된 지식으로 심인성 발기부전에 빠지는 사람이 상당히 많다. 그러므로 당뇨병환자는 정상인보다 더 많은 노력을 하며 합병증의 병발을 미연에 방지하는 것이 가장 중요하다.

• Korean Journal of Biological Psychiatry
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• v.5 no.2
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• pp.278-282
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• 1998

Various neurotransmitters have been proposed as possible mediators of penile erection. Especially, norepinephrine and serotonin might have a important role in sexual arousal and penile erection. And it could be hypothesized that the psychogenic impotence is associated with the depletion or imbalance of norepinephrine and serotonin from evidences, such as the symptomatic manifestation of depression and the antidepressantinduced sexual dysfunction. The authors investigates the association of norepienphrine and serotonin with psychogenic impotence. The psychogenic impotent group(PIG) consisted of twenty-three patients with psychogenic impotence and the controlled group(CG) consisted of twenty-seven patients without psychogenic impotence. PIG had no organic cause accounting for their erectile dysfunction. The Beck Depression Inventory(BDI) and the State-Trait Anxiety Inventory(STAI) were applied to each subject to assess mood, state anxiety(SA) and trait anxiety(TA). Plasma norepinephrine level from systemic blood and 5-hydroxyindoleacetic acid(HIAA) levels from 24-hours urine were measured in each subject. The mean score of BDI of PIG was significantly higher than that of CG(p=0.015). PIG had a tendency of higher TA compared with CG(p=0.054). And also SA was higher in PIG, but did not show significant difference(p=0.193). The level of norepinephrine was significantly lower in patient with psychogenic impotence(p=0.000). And the level of 24-hours urine 5-HIAA was lower in PIG but did not show significant difference(p=0.494). Although the authors did not exclude depressive disorders in PIG, the present findings suggest that psychogenic impotence might have higher depressive mood and trait anxiety, and be associated with the depletion of norepinephrine in systemic blood.