• The Korean Journal of Nuclear Medicine
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• v.30 no.1
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• pp.104-111
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• 1996

We did Tc-99m sestamibi myocardial perfusion SPECT in 36 patients with acute myocardial infarction when they arrived at the emergency room. And we compared myocardial perfusion images with ECG findings. Then we obtained the follows. The myocardial infarction by the obstruction of left coronary descending artery and right coronary artery showed a good concordance in the diagnosis and infarction site between myocardial perfusion images and ECG findings. The 7 patients with myocardial infarction by a left circumflex coronary artery showed a perfusion defect in the lateral wall in myocardial perfusion SPECT images. But 4 patients of them showed ST segment elevation, 2 patients showed ST depression and 1 patient showed normal ECG findings. The diagnostic sensitivity of Tc-99m sestamibi myocardial perfusion SPECT was 100% by a qualified analysis. The perfusion defect site in the myocardial perfusion SPECT were corresponded with the infarct related coronary artery in 31 patients which was diagnosed by coronary angiograpy. The size of perfusion defect in the po1ar map was $31{\pm}18%(M{\pm}SD)$, in the myocardial infarction with left anterior descending coronary arery obstruction, $31{\pm}13% (M{\pm}SD)$ in the myocardial infarction with right coronary artery obstruction and $25{\pm}5.9%(M{\pm}SD)$ in the myocardial infarction with left circumflex coronary artery obstruction. We concluded that emergency myocardial perfusion SPECT images are useful in the diagnose of myocardial infarction and it's very useful when we are difficult to diagnose with ECG like as lateral wall infarction or left bundle branch block.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.235-235
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• 1994

NSAID의 대표적인 유도체인 acetylsalicylic acid(aspirin)은 항혈전 작용이 있다고 밝혀졌고, 주기적인 aspirin의 투여는 심근경색을 예방할 수 있음이 보고되었다. 그러나, 위궤양등 부작용의 발현이 심각하여 위의 목적에 입각한 aspirin의 장기적인 사용에 제약이 되고 있다. 이에 더욱 안전한 유도체인 aspalatone을 합성하였고, 이 물질은 낮은 궤양 유발능을 보이는 유망한 유도체로 개발중에 있다. 본 연구는 aspalatone의 in vivo 항염증 활성을 밝히기 위하여 시행하였다.

• Journal of the korean veterinary medical association
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• v.40 no.2
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• pp.145-156
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• 2004

심부정맥(Cardiac arrhythmia)이란 심장내 박동, 율동, 충동 발생 및 전도장애를 유도하는 질환을 말하며, 주로 심근경색이나 심장비대증 같은 심장의 해부학적 질환과 약물중독 및 전해질 불균형에 의해 발생한다. 부정맥은 정상적인 심근 활성을 차단하여 심장박출을 감소시키므로 때로 생명을 위협하기도 한다. 본 종설에서는 심장의 전도계에 관련된 정상생리와 부정맥의 병리적 발생기전 및 부정맥 치료제에 대한 분류 및 약리기전에 대해 기술하고자 한다.

• 대한핵의학회:학술대회논문집
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• 1981.05a
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• pp.128.2-128.2
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• 1981

• 대한핵의학회:학술대회논문집
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• 1999.11a
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• pp.31.2-31.2
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• 1999

• Journal of Korean Public Health Nursing
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• v.28 no.3
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• pp.565-573
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• 2014

Purpose: Health Insurance Review & Assessment Service (HIRA) launched an Acute Myocardial Infarction(AMI) assessment for the Payment For Performance(Quality Incentives) Pilot Project from July 2007. Assessment measures of AMI were composed of five process measures and one outcome measure, and each measure was incorporated into one composite quality score to Pay for Performance. Method: For calculation of composite quality score, we considered weighting for the measures using the Delphi method. The questionnaire was composed of three measure groups, 'Reperfusion rate'(Fibrolytic therapy received within 60 minutes of hospital arrival, Primary Percutaneous Coronary Intervention within 120 minutes of hospital arrival), 'Medication prescription rate'(Aspirin at arrival, Aspirin prescribed at discharge, Beta-blocker prescribed at discharge) and 'Survival Index'(30-day mortality rate). Result: A panel composed of 18 and completed a questionnaire by allocation of 10 scores to the three above mentioned measure groups. The Delphi was carried out until three rounds of surveys. In conclusion, each measure group was weighted differently and the 10 scores were allocated as 4.5 to 'Reperfusion rate', 2.5 to 'Medication prescription rate', and 3.0 to 'Survival Index'. Conclusion: The results of this study proposed the calculation method for weighting of Acute Myocardial Infarction quality indicators.

• Journal of Chest Surgery
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• v.39 no.1 s.258
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• pp.64-67
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• 2006

Anterior papillary muscle rupture caused by occlusion of the first diagonal branch is reported to be very rare. A 66-year-old woman was transferred to our hospital for acute myocardial infarction and cardiogenic shock. Echocardiography and angiography revealed severe mitral regurgitation caused by rupture of the anterior papillary muscle and the complete occlusion of the first diagonal branch. In an emergent setting, she had been successfully treated by mitral valve replacement and coronary artery bypass grafting. She was discharged on postoperative twelfth day without any event.

• Journal of Yeungnam Medical Science
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• v.5 no.2
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• pp.247-254
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• 1988

Serum lactate dehydrogenase isoenzymes are separated 5 fractions($LD_1-LD_5$) in normal serum by agrose electrophoresis. An unusual band on the cathodic side of $LD_5$ isoenzyme has been found on lactate dehydrogenase electrophores is of serum, called $LD_6$, and the presence of which signifies a poor prognosis for the patients of myocardial infarction. In recent, we have experienced $LD_6$ in two patients with myocardial infarction. Cardiac arrest was noted within 24 hours after exhibition of $LD_6$ extraband and they did not recover from their illness.

• Journal of Korean Clinical Nursing Research
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• v.21 no.3
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• pp.389-400
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• 2015

Purpose: The purpose of the study was to identify and describe illness experiences of men with myocardial infarction. Methods: Data were collected through individual in-depth interviews with 10 male patients. Analysis was done using phenomenological analysis. Results: Five theme clusters including 11 themes emerged. 1) "Unexpected grave disease instantly dividing life and death" describes the great ignorance of symptoms and experience as a survivor narrowly escaping death. 2) "A disease still not considered a disease" illustrates the paradoxical and confusing situation between low level of awareness of the severity of the disease and high level of reflection on their unhealthy lifestyles. 3) "Fighting against me for health" illustrates their resolution and action to maintain health while experiencing helplessness. 4) "Relationships in a no-win situation" contains defensive posture due to social stigma and the dilemma of family breadwinners. And 5) "Introspection of past and future life" describes positive turnings in life through enlightenment in addition to remorseful feeling about the past and persistent worry of death. Conclusion: Health professionals need to support men with myocardial infarction by providing family-oriented and empowerment-based self-management interventions to lead to success in their illness journey and to improve their quality of life.

• Journal of Chest Surgery
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• v.43 no.5
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• pp.538-541
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• 2010

Heparin-induced thrombocytopenia (HIT) is a clinicopathologic condition and adverse drug reaction caused by immunoglobulin G (IgG) antibodies directed against the heparin-platelet factor 4 complex. HIT with thrombosis (HITT) could lead to limb amputation, stroke, myocardial infarction, and death. We report on the successful management of a HITT patient with argatroban therapy.