• Korean Journal of Optics and Photonics
• /
• v.23 no.1
• /
• pp.23-31
• /
• 2012

In this paper, we developed a frequency-domain diffuse optical imaging (DOI) system for imaging non-invasively using near-infrared (NIR) light sources and detectors. 70-MHz modulation and a homodyne scheme were adopted. By calibration of the coupling coefficients, concurrent detection measurements by 4 detector sets were optimized. We presented experimental reconstruction images of absorption and scattering coefficients in a liquid phantom, located an anomaly in the phantom and determined its optical properties. The images by the multi-channel concurrent detection were improved over the results by single-channel sequential detection. Tomographic slices of absorption and scattering coefficients in the phantom with an anomaly were also presented.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.31 no.3
• /
• pp.147-153
• /
• 2018

Cracking in concrete structure must be examined according to appropriate methods, to ensure structural serviceability and to prevent structural deterioration, since cracks opened wide for a long time expedite corrosion of rebar. A site investigation is conducted in a regular basis to monitor structural deterioration by tracking growing cracks. However, the visual inspection are labor intensive. and judgment are subject. To overcome the limit of the on-site visual investigation image processing for identifying the cracks of concrete structures by analyzing 2D images has been developed. This study develops a unique 3D technique utilizing a line laser and its projection image onto concrete surfaces. Automated process of crack detection is developed by the algorithms of automatizing crack map generation and image data acquisition. Performance of the developed method is experimentally evaluated.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.49 no.9
• /
• pp.353-361
• /
• 2012

In this paper, we propose a improvement method of vision inspector for T type welding nut using an auto sorting system. We used edge and thread detection with histogram of image which is captured by machine vision camera. We also used a binary morphology operation for a detection of spot. A major problem in this vision inspector is abnormal operation caused by degradation of image acquired. These degradations caused by oil pollution on conveyer belt. For overcome this problem, we introduce a pre-processing using a masked histogram equalization on the image acquired. Histogram equalization is applied on masked region (nut part) for increase contrast. As a result, we can remove features caused by oil pollution on background and reduce a ratio of abnormal operation from 10.0 % to 0.2 %.

• The Journal of the Acoustical Society of Korea
• /
• v.39 no.6
• /
• pp.549-558
• /
• 2020

In this paper, the method is discussed such that the robustness of automatic initiated narrowband target tracking is improved in passive sonar. In the case of automatic tracking initiation as target in passive sonar, due to a number of clutter, the clutter is initiated as target and tracked which prohibits the operation capability. The associated probability and information entropy of measurements, extracted from detection data, is calculated to keep going on automatic target initiation and tracking of true target, but reduce the automatic initiation and tracking of clutter. If the association probability and information entropy of the extracted measurements is satisfied for the predefined conditions, the procedure of automatic initiation begins. Using sea-trial data, simulations are executed and the results from the proposed method indicate that it keeps the automatic target initiation and tracking of true target and suppresses the automatic target initiation and tracking of clutters in contrary to the conventional method.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.18 no.3
• /
• pp.185-191
• /
• 2018

In this paper, an improved Norton amplifier is proposed and the problems caused by the current input in the Norton amplifier, which has advantages in current transmission, are analyzed. The output of the voltage follower consisting of an operational-amplifier with constant output voltage characteristics is used as an input terminal of the proposed circuit. It is configured to detect the power supply current passing through the voltage follower and extract the current from the input terminal. The performance of the improved Norton amplifier is verified at experiment according to the input current. The results are compared with conventional Norton amplifier. Consequently, the input offset voltage, which is a problem in the conventional Norton amplifier, was removed in the proposed circuit. In addition, the average error of the output voltage with respect to the input current was reduced to 4.755%. It is verified that the characteristics of the proposed circuit are improved.

• Analytical Science and Technology
• /
• v.16 no.4
• /
• pp.325-332
• /
• 2003

To analyze co-planar PCBs in food, the isotopic dilution method by high resolution gas chromatography/high resolution mass spectrometry was applied. Among 209 PCB congeners, 12 congeners (#77, #81, #126, #169, #105, #114, #118, #123, #156, #157, #167 and #189) were chosen as target compounds that were toxic congeners re-assessed by WHO in 1998. Milk and milk products including cheese and butter were collected as food samples. Samples were homogenized, spiked with the known amount of the standard mixture and extracted. After extraction, extracts were cleaned up by sulfuric acid impregnated silica gel, purified on silica gel and alumina column chromatography and then analyzed by HRGC/HRMS. As results, the overall recoveries were ranged from 83% to 106% and the limit of detection was about 0.1 pg/g at signal/noise>3. Levels of targets in the selected food samples were 0.001~0.107 pgWHO-TEQ/g.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.22 no.2
• /
• pp.233-242
• /
• 2018

Previous works for detecting arrhythmia have mostly used nonlinear method such as artificial neural network, fuzzy theory, support vector machine to increase classification accuracy. Most methods require higher computational cost and larger processing time. Therefore it is necessary to design efficient algorithm that classifies PVC(premature ventricular contraction) and decreases computational cost by accurately detecting feature point based on only R peak through optimal R wave. For this purpose, we detected R wave through optimal threshold value and extracted RR interval and R peak pattern from noise-free ECG signal through the preprocessing method. Also, we classified PVC in realtime through RR interval and R peak pattern. The performance of R wave detection and PVC classification is evaluated by using 9 record of MIT-BIH arrhythmia database that included over 30. The achieved scores indicate the average of 99.02% in R wave detection and the rate of 94.85% in PVC classification.

• Journal of Broadcast Engineering
• /
• v.23 no.4
• /
• pp.484-494
• /
• 2018

The uniform motion blur removing algorithm of Cho et al. has the problem that the edge region of the image cannot be restored clearly. We propose the effective algorithm to overcome this problem by using shock filter that reconstructs a blurred step signal into a sharp edge, and convolutional neural network (CNN) that learns by extracting features from the image. Then uniform motion blur kernel is estimated from the latent sharp image to remove blur in the image. The proposed algorithm improved the disadvantages of the conventional algorithm by reconstructing the latent sharp image using shock filter and CNN. Through the experimental results, it was confirmed that the proposed algorithm shows excellent reconstruction performance in objective and subjective image quality than the conventional algorithm.

• Herbal Formula Science
• /
• v.26 no.3
• /
• pp.183-193
• /
• 2018

Objectives : In Traditional Korean Medicine, Epimedium koreanum Nakai has diverse pharmacological activities to treat impotence, forgetfulness, cataract and exophthalmos. Present study investigated anti-fibrogenic effects of E. koreanum water extract (EKE) in hepatic stellate cells (HSCs). Methods : To study anti-fibrogenic effects of EKE, LX-2 cells, a human immortalized HSCs, were pre-treated with $3-300{\mu}g/mL$ of EKE, and then subsequently exposed to 5 ng/mL of transforming growth $factor-{\beta}1$ ($TGF-{\beta}1$). Expression level of ${\alpha}-smooth$ muscle actin was determined by immunoblot analysis. Phosphorylation of Smad, transactivation of Smad, and expression of plasminogen activator inhibitor-1 (PAI-1) were monitored to investigate the effect of EKE on $TGF-{\beta}1-mediated$ signaling pathway. Results : Up to $100{\mu}g/mL$, EKE did not show any cytotoxicity on LX-2 cells. Pre-treatment of EKE ($100{\mu}g/mL$) significantly inhibited ${\alpha}-smooth$ muscle actin expression induced by $TGF-{\beta}1$. In addition, EKE significantly decreased Smad2 and Smad3 phosphorylations, Smad binding element-driven luciferase activity and PAI-1 expression by $TGF-{\beta}1$. Of three flavonoid compounds found in EKE, only quercertin ($30{\mu}M$) attenuated $TGF-{\beta}1-mediated$ PAI-1 expression. Conclusion : These results suggest that EKE has an ability to suppress fibrogenic process in HSCs via inhibition of $TGF-{\beta}1/Smad$ signaling pathway.

• Microbiology and Biotechnology Letters
• /
• v.37 no.2
• /
• pp.105-109
• /
• 2009

Among signal transduction systems by protein phosphorylation Akt/PKB protein kinase which is one of serine/threonine kinases, is known to regulate the survival and death of the cell and glucose metabolism. Thus, Akt/PKB protein kinase has been used as one of the target proteins to find anti-cancer agents from natural products. In this study, human Akt/PKB protein kinase was expressed in Escherichia coli expression system for the mass production. Human Akt/PKB protein kinase expressed in E. coli formed inclusion body under the general condition. However, most of the expressed protein was solubilized under the culture temperature at $27^{\circ}C$ and 0.01-0.09 mM of IPTG for induction of the protein expression. The expressed protein was purified using $Ni^{2+}$-NTA agarose column and confirmed by using anti-Akt antibody. Subsequently, the purified human Akt/PKB protein kinase was activated by in vitro phosphorylation using cellular extract containing kinases. The activated protein was confirmed to phosphorylate the specific fluorescent peptide specially designed as the artificial substrate for Akt/PKB protein kinase.