• Title/Summary/Keyword: 신증후군

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Clinico-epidemiologic Study of Henoch-Schönlein Purpura in Children, 1987 through 2003 (Henoch-Schönlein 자반증의 임상 역학적 연구(1987-2003년))

  • Choi, Sun-Mee;Lee, Kyung-Yil
    • Clinical and Experimental Pediatrics
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    • v.48 no.2
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    • pp.174-177
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    • 2005
  • Purpose : We evaluated children with Henoch-$Sch{\ddot{o}}nlein$ purpura(HSP) in terms of epidemiology and clinical characteristics. Methods : A total of 424 medical records of children with HSP admitted to The Catholic University of Korea, Daejeon St. Mary's Hospital, from 1987 to 2003 were retrospectively analyzed. Results : The mean annual number of cases was $25.1{\pm}7.9$ and no one year showed an outbreak. There was a steady number of patients throughout the year with a decrease during the summer season. The male-to-female ratio was 1.3 : 1 with the median age of the patients being 6-years-old. The age distribution showed a peak at age 6 in a bell-shaped distribution curve. Purpura was noted in 100 percent of the patients, gastrointestinal involvement in 53.8 percent, joint involvement in 40.8 percent, and renal involvement in 18.9 percent. Nephrotic syndrome occurred in 1 percent of all patients. Conclusion : The epidemiologic and clinical features of HSP were similar to those of other regions in Korea and foreign nations, irrespective of time.

Comparison the Prevalence of Metabolic Syndrome and Obesity Index between Patients with Silent Lacunar Infarction and Normal Controls in a University Hospital (일개 대학병원에 내원한 무증상성 열공성 뇌경색 환자와 정상인에서 비만 지수와 대사증후군 유병률 비교)

  • Jeong, Hyun-Yun;Kim, Do-Kyung;Son, Ho-Yong;Shin, Yoon-Ri;Lee, Jae-Wook;Kim, Kyoung-Min;Kim, Young-Kyun;Kwon, Jung-Nam;Park, Sun-Mi
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.3
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    • pp.519-524
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    • 2010
  • This clinical study was done to examine comparison the prevalence of metabolic syndrome and obesity index between patients with silent lacunar infarction and normal controls. We compared the components of metabolic syndrome and obesity index between patients silent lacunar infarction(n=62) and normal controls(n=72). The analysis of the data was done by Frequency Analysis, two sample t-test, Chi-square Test. Hypertension and diabetes mellitus was significantly higher in patients of silent lacunar infarctions. Body mass index (BMI), waist-hip ratio (WHR), body fat percentage, obesity ratio, metabolic syndrome were higher significantly in patients of silent lacunar infarctions than normal controls. Although statistically insignificant, waist circumference showed relatively higher in patients of silent lacunar infarction. This result emphasizes the importance of managing that hypertension, diabetes, body mass index (BMI), waist-hip ratio (WHR), body fat percentage, obesity ratio, metabolic syndrome in silent lacunar infarction.

DECREASE OF OXYGEN SATURATION DURING DENTAL TREATMENT UNDER GENERAL ANESTHESIA OF DOWN SYNDROME PATIENT WITH CONGENITAL HEART DISEASE -A CASE REPORT- (선천성 심장질환을 가진 다운증후군환자에서 치과치료를 위한 전신마취 시 산소포화도 하강 -증례보고-)

  • Seo, Kwang-Suk;Chang, Ju-Hea;Shin, Teo-Jeon;Kim, Hyun-Jeong
    • The Journal of Korea Assosiation for Disability and Oral Health
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    • v.5 no.1
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    • pp.18-22
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    • 2009
  • A 26-year-old female patient with Down syndrome visited to recieve dental treatment under gnenral anesthesia 6 years ago. The patient had difficulties in oral examination, radiograph taking and laboratory test. The patient had congenital heart disease and medical consultation based on the echocardiography was provided by a cardiologist indicating that the patient could tolearte general anesthesia during dental treatment. And two times of general anesthesia were administered during a dental treament with the interval of 3 years and no postoperpative complicaton was reported. At the third dental operation, the patient had a relatively good condition and her prescreening test revealed no abnormalities. Without further consultation with a cardiologist, general anesthesia was administered to the patient. Anaesthesia was based on thiopental and ventilation of desflurane and $N_2O$ in oxygen via an endotracheal tube with an appropriate monitoring. During the maintenance of anesthesia, the blood pressure of the patient started to drop and the oxygen saturation also began to decrease. Consequently, the proceding operation was discontinued and also inhalation anesthesia was ceased. As the patient was recovered from anesthesia, her systemic conditions were alleviated. After the complete recovery of the patient, she visited the cardiologist, and the cardiologic test revealed her severe right ventricular dilatation. In the anesthesia of patients with congenital heart disease, information on their systemic conditions needs to be undated from the medical consultation, which assures the safety of treatment.

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Moxibustion Therapy for the Pain Relief in Patient with Type I CRPS: a Case Report (뜸치료의 제 1형 복합부위통증증후군 환자에 대한 통증완화 효과: 증례 보고)

  • Cho, Hyun-Woo;Shin, Byung-Cheul;Shin, Mi-Suk;Hwang, Eui-Hyoung;Sul, Jae-Uk
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.3
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    • pp.79-87
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    • 2011
  • Objectives : The aim of this study was to observe the pain relief effect of moxibustion therapy in a patient with complex regional pain syndrome(CRPS). Methods : A male with type I CRPS, 48-year-old, who suffered from severe pain and paresthesia on his legs despite of treatments of oral medications and spinal cord stimulation was treated by indirect moxibustion following Korean medicine dianosis. Total 20 moxibustion treatments(once daily, 5 days a week, for 4 weeks) were given on the 4 acupoints(both side) where known to be effective fro the CRPS. Visual analogue scale(VAS), digital infrared thermal imaging(DITI), Beck depression index(BDI) were evaluated before and after the treatments. Pain relief, thermal changes on affected legs, and improvement of depression scale were observed after the treatments. Results : As for DITI, right thigh showed low temperature compared with left on before the treatments. While after the treatments, DITI showed similar temperature in both legs at discharge day. Conclusions : Though it is a case report, moxibustion therapy might have pain relief effect. Further rigorous case series and controlled trials are warranted.

Temporal Relationship between Symptomatic and Electrophysiological Improvement to Postoperative Carpal Tunnel Syndrome Patients: Preliminary study (수근관 증후군 환자의 수술 후 증상 호전과 전기생리학적 호전시기의 관련성에 관한 예비연구)

  • Ko, Yeong-Chae;Lee, Yeong-Bae;Kim, Yoon-Bong;Yoo, Chan-Jong;Shin, Won-Chul;Park, Hyeon-Mi;Ha, Kyung-Sik;Shin, Dong-Jin
    • Annals of Clinical Neurophysiology
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    • v.5 no.2
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    • pp.177-180
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    • 2003
  • Background and Objectives: A nerve conduction study (NCS) has been known as a useful method to evaluate the therapeutic effect of operation in carpal tunnel syndrome (CTS). To evaluate the temporal relationship between symptomatic and electrophysiological improvement, we compared the preoperative symptoms and electrophysiological results with postoperative those. Methods: We analyzed the NCS changes before and after minimal release of carpal tunnel in 26 patients (34 hands) with CTS. The time of postoperative symptomatic changes, postoperative electrophysiological changes and temporal relationship between symptomatic and electrophysiological changes were evaluated. Results: The mean age was $49{\pm}13$ years. The proportion of males to female was 8 and 92 percent. The median interval days between date of operation and those of postoperative NCS was 28.5 days. Postoperative symptoms improved in 17 hands, slightly improved in 13 hands, and have not changed in 4 hands. Electrophysiological improvements after operation were observed in 26 hands, and mostly appeared within 2 months. Symptomatic relief accompanied with electrophysiological improvement reported in 13 hands (50%). Moreover, the four hands with symptom, not relieved by decompression, showed electrophysiological improvement. Conclusions: In this study, electrophysiological improvement was in consistency with symptomatic relief to some extent, but we got the result of disagreement between electrophysiological and symptomatic improvement.

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Clinical and Electrophysiological Changes after Open Carpal Tunnel Release: Preliminary Study of 25 Hands (수근관증후군 수술 전후 임상증상과 전기생리학적 검사소견의 변화: 25손을 대상으로 한 예비연구)

  • Yang, Ji Won;Sung, Young Hee;Park, Kee Hyung;Lee, Yeong Bae;Shin, Dong Jin;Park, Hyeon Mi
    • Annals of Clinical Neurophysiology
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    • v.16 no.1
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    • pp.21-26
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    • 2014
  • Background: Electrophysiological study has been known as a useful method to evaluate the therapeutic effect of operation in idiopathic carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the clinical and electrophysiological changes after carpal tunnel release (CTR) compared to the preoperative results. Methods: We analyzed the changes of nerve conduction study (NCS) before and after minimal open carpal tunnel release in 18 patients (25 hands) with CTS. Follow-up study was performed over 6 months after operation. Results: Clinical improvement was seen in all cases after CTR. In contrast, electrophysiological improvement was various depending on the parameters; the mean median sensory latency and nerve conduction velocity (NCV) improved significantly (p = 0.001). The mean median motor latency also improved, but NCV and compound muscle action potential (CMAP) amplitude did not change. The extent of improvement was evident in moderate CTS, but not in severe CTS. Conclusions: In this preliminary study, all subjects who underwent CTR achieved a clinical relief along with a significant improvement of electrophysiological parameters such as median sensory latency, sensory NCV and median distal motor latency. After CTR, a number of cases with mild to moderate CTS showed a prominent improvement of clinical and electrophysiological parameters, while fewer improvements were seen in severe CTS, although it did not reach the statistical significance.

Biomarkers for Combat-Related Stress and Fatigue-Mitigating Drugs Discovery (전투 스트레스 및 피로 완화 약물 탐색을 위한 생체지표)

  • Koo, Hyojin;Kim, Chang Yul;Kim, Yeonkyung;Sin, So Jung;Cheon, Kicheol;Kim, Dongsoo
    • Journal of the Korea Institute of Military Science and Technology
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    • v.21 no.2
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    • pp.246-254
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    • 2018
  • Psychological stress and physical fatigue, such as anxiety, fear, sleep disturbance, etc., caused by exposure to the war, can lead to post-traumatic stress syndrome(PTSD) or war syndrome. The military has also prepared for drug use to minimize war syndrome and preserve combat strength. However, efforts to prevent war syndrome are still lacking. This study was conducted to identify biomarkers that can track psychophysiological changes. Psychophysiological changes associated with PTSD can be divided into four main categories. The four categories are behavioral changes, changes in brain cognition, neuroimmunological changes, and changes in innate immunity. This study suggest that biomarker profile can be made by the distance moved and the anxiety-like behavior in the open field for behavior category, brain BDNF levels in the brain cognition category, serum corticosterone in the neuroimmunology category, and inflammatory cytokine levels in the innate immunity category.

Kimura's Disease of the Elbow - A Case Report - (주관절 부위에 발생한 Kimura씨 병 - 증례 보고 -)

  • Cho, Chul-Hyun;Sohn, Sung-Won;Kang, Chul-Hyung;Oh, Geon-Myung
    • Clinics in Shoulder and Elbow
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    • v.12 no.1
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    • pp.89-93
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    • 2009
  • Purpose: Kimura's disease is an uncommon benign lymphoproliferative inflammatory disorder with an unknown etiology. The recurrence rate after surgical excision is relatively high and renal involvement is its only systemic manifestation. The condition mainly involves the head and neck, and peripheral involvement is extremely rare. Materials and Methods: We encountered the case of a 28-year-old man who had a non-tender mass with mild brownish skin color changes and pruritus around the medial side of the distal arm and elbow. Results: The peripheral blood investigation revealed peripheral eosinophilia and elevated serum IgE levels. Magnetic resonance imaging showed an isointensity signal relative to the muscle on the T1-weighted images and hyperintensity signal relative to the muscle on the T2-weighted images. Conclusion: A marginal resection of the lesion was performed and there was no recurrence at 2 years postoperatively.

The Clinical Observation on 1 Case of Patient with Central Cord Syndrome (중심성 척수 증후군 치험 1례)

  • Ryu, Do-Kyun;Lee, Ji-Hun;Oh, Kyung-Hwan;Park, Dong-Joon;Park, Soon-Il;Han, Chang-Ho;Chung, Sung-Hyun;Shin, Gil-Cho;Lee, Won-Chul;Hwang, Joo-Won
    • Journal of the Korean Institute of Oriental Medical Informatics
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    • v.11 no.2
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    • pp.23-31
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    • 2005
  • Central cord syndrome (CCS) is the most common incomplete spinal cord injury (SCI) syndrome, occured by cervical hyperextension injury. It is characterized by disproportionately greater motor impairment in the upper extremities compared to the lower extremities, bladder dysfunction, and variable degrees of sensory loss below the level of injury. Recently 36 year-old male was admitted with upper motor neuron weakness, sensory loss in the upper extremities and stiff neck. We report the improvement of his symptoms through both western medical treatment and oriental medical treatment.

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Case Study of a Patient with Callosal Disconnection Syndrome Secondary to an ACA Infarction (전대뇌동맥 경색으로 인한 뇌량 분리 증후군 환자의 치험 1례)

  • Jung, Hyun-Jung;Hwang, Joo-Won;Jo, Eun-Young;Choi, Dong-Jun;Han, Chang-Ho;Jung, Seung-Hyun;Sin, Gil-Jo;Lee, Won-Chul
    • The Journal of Internal Korean Medicine
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    • v.27 no.3
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    • pp.762-769
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    • 2006
  • A callosal disconnection syndrome results in the functional independence of each hemisphere caused by ACA infarction, head injury or callosal operation for epilepsy. Clinical features are characterized by left unilateral tactile anomia, left unilateral agraphia, left unilateral apraxia, difficulty in copying drawings, dyscalculia and alien hand syndrome. Taeumchowe-tang(太陰調胃湯) is used to treat Taeumin(太陰人) Wewansuhanpyohanbyung(胃脘受寒表寒病). A 47 year-old man, following callosal infarction, was detected on MRI with left agraphia, dyscalculia and alien hand syndrome, but no left ideomotor apraxia or left apraxia. He was treated with Taeumchowe-tang. Significant improvement of clinical symptoms was seen, so it is here reported.

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