• Title/Summary/Keyword: 신이식

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Thoracoabdominal Aortic Aneurysm Repair after Renal Transplantation (신장 이식후 발생한 해리성 흉복부 대동맥류의 외과적 치험)

  • 김대영;문광덕
    • Journal of Chest Surgery
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    • v.29 no.4
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    • pp.449-453
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    • 1996
  • A successful resection of dissecting thoracoabdominal aortic aneurysm is presented in a patient who had undergone kidney transplantation 20 months previously. Because the transplanted kidney is more sensitive to ischemia than the normal kidney, a femoro-femoral bypass with a pump oxygenator was used for perfusion of the transplanted kidney during crossclamping. During the clamping time of 1)8 minutes, kidney perfusion was maintai ed with a perfusion pressure of (19 to 31) 27mmHg and the flow was 0.53 to 0.81 L/min. 32mm sized Hemashield (22 Cm in length) was interposed. The postoperative course was uncomplicated. We believe that performing the femoro- femoral bypass with a pump oxygenator is an effective and simple method for renal and spinal protection in such operations.

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Design of the XML for Decision-making in the Medical Treatment (의료부문 의사결정지원을 위한 XML 설계)

  • Lee, Sang-Young
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2009.01a
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    • pp.5-8
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    • 2009
  • XML(eXtensible Markup Language)을 통하여 의료부문의 Arden Syntax틀 표현하기 위한 모델은 Arden Syntax의 이식성을 증가시키기 위하여 개발된다. Arden Syntax는 의료분야에서의 논리적인 시스템에 활용되는 의학적인 의사 결정을 위한 언어이다. 또한 의료영역에서의 의사결정들을 컴퓨터에 의해 실행이 가능하도록 하기 위하여 고안된 언어이다. 본 논문에서는 의료부문에서의 Arden Syntax를 XML로 변화하기 위한 ArdenML을 설계한다. 즉 ArdenML에 대한 스키마와 스타일시트 등을 제시하고 MLM 예제를 통하여 검증한다. 즉 점차 이식성측면이 강조되는 Arden Syntax를 위한 XML 스키마 및 스타일시트를 구축하며 제시한다.

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Implement and Effects of Pronunciation Correction App for Teenagers with Hearing Aids (청력보조기를 이식받은 청소년을 위한 발음교정 앱 구현과 효과 정리)

  • Shin, Ji-Woo;Lee, Ji-Oun;Im, Jisu;Lim, Sung-Hyun
    • Annual Conference of KIPS
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    • 2017.11a
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    • pp.1045-1048
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    • 2017
  • 기존에 있는 발음연습 앱이 청소년 청각장애인이 언어치료용으로 사용하기에 부적절한 이유와 그들에게 맞는 언어치료 앱 도입 필요 이유를 설명한다. 현장에서 일하시는 언어치료사와 청각장애인의 의견을 수용하여 개발한 청소는 청각장애인을 위한 앱의 시스템 구성도와 서비스 흐름도, 개발 앱의 기능과 기술, 사용자 시나리오를 설명하여 인공와우를 이식받은 청소년 청각장애인이 언어치료 앱인 '발연기'를 통해 어떻게 언어치료를 받을 수 있을지에 대한 연구이다.

The Effect of Local Irradiation in Prevention and Reversal of Acute Rejection of Transplanted Kidney with High-dose Steroid Pulse (국소적 방사선조사의 신장이식 후 거부반응에 대한 예방적 및 치료적 효과)

  • Kim I. H.;Ha S. W.;Park C. I.;Kim S. T.
    • Radiation Oncology Journal
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    • v.4 no.1
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    • pp.15-20
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    • 1986
  • From 1979 to 1984, 39 local allograft irradiations were given to 29 patients: 10 irradiations were administered for prevention and 29 for reversal of acute rejection of transplanted kidney. Three doses of 150 cGy every other day were combined with high-dose of methylprednisolone pulse (1 gm/day) for 3 days. For prevention of acute rejection, local irradiation was delivered on the days 1, 3, and 5 after the transplantation, and for reversal, irradiation started after the diagnosis of acute rejection. Eight out of 10 patients irradiated for prevention had acute allograft rejection, and, what is more, there was no surviving graft at 15 months after transplantation. Reversal of acute rejection was achieved in $71\%$. When the pre-irradiation level of serum creatinine was below $5.5mg\%$, the reversal rate was $93\%$, but above $5.5mg\%$ the reversal rate was only $17\%$ (p<0.01). Reirradiation after failure was not successful. Among 15 reversed patients, $7(47\%)$ had subsequent rejection (s). The functional graft survivals at 6 month, 1, 2, and 3 year were $70\%,\;65\%,\; 54\%,\;and\;54\%$, respectively. Therapeutic irradiation resulted in better graft survival when serum creatinine was below $5.5mg\%$ (p<0.001) or when irradiation started within 15 days after the diagnosis of acute rejection (p<0.001).

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Analysis of Acute Kidney Injury in Pediatric Patients with Stem Cell Transplantation (소아에서 조혈모세포이식 후 급성 신질환의 분석)

  • Kim, Sae-Yoon;Choi, Jung-Youn;Ha, Jeong-Ok;Park, Yong-Hoon
    • Childhood Kidney Diseases
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    • v.13 no.2
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    • pp.130-137
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    • 2009
  • Purpose : Stem cell transplantation (SCT) has gained worldwide acceptance as a treatment for hematologic disorders. This study was performed to evaluate the clinical characteristics and outcomes of the acute kidney injury after SCT in children. Methods : The records of 53 patients who were treated with SCT at the pediatric department of Yeungnam University Hospital between January, 1996 and April, 2009 were used as subjects. Their were divided into two groups ; 'Early renal insufficiency' (ERI, n=18) and 'Non-early renal insufficiency' (NERI, n=35). ERI had greater than 25% of drop in GFR after SCT. Results: Total 53 patients were analyzed. In cord blood SCT (n=11), ERI was 4 (36.4%) and NERI was 7 (63.6%). In bone marrow SCT (n=16), ERI was 8 (50.0%) and NERI was 8 (50.5%). In autologous peripheral blood SCT (n=26), ERI was 6 (23.1%) and NERI was 20 (76.9%). There is no difference in both groups according to kinds of SCT. GVHD was developed in 22 patients, and there is no difference in each group. Twenty two of 53 patients died. ERI was 12 (66.7%) and NERI was 10 (28.6%). Acute renal failure is most important cause of the deaths. Conclusion : Out of 53 pediatric patients who were treated with SCT, 18 patients had greater than 25% of drop in GFR. There is no difference in both groups according to kinds of SCT. GVHD was found in 22 patients and there is no relation between GVHD development and acute kideney injury.

Recovery of Delayed Graft Function after Calcineurin Inhibitor Sparing Regimen in a Renal Transplant Patient with Calcineurin Inhibitor Toxicity: A Case Report

  • Kang, Seok Hui;Yun, Woo Sung;Cho, Kyu Hyang;Do, Jun Young;Yoon, Kyung Woo;Park, Jong Won
    • Korean Journal of Transplantation
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    • v.28 no.3
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    • pp.165-168
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    • 2014
  • The recipient candidate was a 51-year-old male with end-stage renal disease owing to diabetes mellitus. The initial immunosuppressive regimen included basiliximab for induction and tacrolimus, mycophenolate mofetil, and steroids. Urine output was 413 mL/day on the operative day and 100 mL/day on the postoperative day (POD) 1. There was no definite stenosis of the ureter or vessels. He had anuria on POD 2~4 and he had undergone hemodialysis. His serum creatinine level did not decrease. Therefore, a graft biopsy was performed on POD 4. The pathologic finding was consistent with acute calcineurin inhibitor (CNI) toxicity. There was no evidence of rejection or acute tubular necrosis. Anuria continued on POD 6; therefore, we started sirolimus instead of a CNI based regimen. Graft function was gradually recovered 1 day after reduction of CNI dose and hemodialysis was stopped. The serum creatinine level was normalized on POD 10. He was discharged on POD 21.

Effect of commercial Makgeolli on tumor growth in tumor xenograft mice (종양이식 모델 쥐에서 동결건조 시판 막걸리가 종양성장에 미치는 영향)

  • Shin, Eun-Ju;Kim, JaeHo;Seong, Ki-Seung;Yum, Sung-Kwan;Hwang, Jin-Taek
    • Food Science and Preservation
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    • v.23 no.1
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    • pp.104-109
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    • 2016
  • The purpose of this study was to evaluate the inhibitory effect of commercial Makgeolli on tumor growth in human gastric adenocarcinoma cells (AGS) in a xenograft cancer model, transplanted with AGS cells. Commercial Makgeolli was first dealcoholized by evaporation and used as the test sample. We detected a significant increase in the volume and weight of tumor in nude mice (induction) that were transplanted with AGS cells. Administration of $100mg/kg{\cdot}day$ group (ML), and $500mg/kg{\cdot}day$ group (MH) dealcoholized commercial Makgeolli significantly decreased tumor growth. In this study, 5-FU $18mg/kg{\cdot}day$ was used as a positive control for tumor growth inhibition. Additionally, determination of the body weight of both the groups revealed no side effects after the administration of dealcoholized commercial Makgeolli. Using the cell culture system, we also evaluated the effect of dealcoholized commercial Makgeolli on caspase-3/7 activity in the AGS cells. Treatment with dealcoholized commercial Makgeolli increased the activation of caspase-3/7 and the apoptotic markers in AGS cells in a dose-dependent manner. Therefore, dealcoholized commercial Makgeolli can be used for cancer prevention.

국제 보안 API 표준화 동향

  • 박수진;신동명;김학범;최용락
    • Review of KIISC
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    • v.11 no.1
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    • pp.55-63
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    • 2001
  • 다양한 응용프로그램에서 개별적인 보안기능의 개발은 중복된 노력의 투자는 물론 호환성과 이식성이 부족하므로 상업적 상품으로 기대되는 모듈화와 내구성을 제공하지 못한다. 따라서, 각 응용프로그램에서 공통적으로 사용할 수 있는 보안 API 표준화가 관심을 갖고 국제적으로 추진되고 있다. 본 논문에서는 널리 알려진 보안 API 표준으로써 IETF의 GSS-API, X/OPEN의 GCS-API, 마이크로소프트의 CryptoAPI, RSA의 Cryptoki, Intel의 CSSM-API를 중심으로 표준화 동향을 조사 분석하였다.

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기획리포트 - 당뇨병에 필요한 검사들 (7)당뇨병성 신증을 알아보는 검사

  • 한국당뇨협회
    • The Monthly Diabetes
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    • s.240
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    • pp.62-64
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    • 2009
  • 당뇨병성 신증이라 하면 임상적으로 당뇨병환자에서 염증이 없는 소변에서 단백뇨가 지속적으로 나타남을 의미하는 것이다. 이는 다른 신장질환이나 신부전증 등에 의하지 않고 당뇨병의 합병증으로 발생된 경우를 의미한다. 당뇨병환자의 25~50%가 신 질환을 갖게 되며 결국 투석이나 신장이식을 받게 된다. 20년 이상 기왕력을 가진 제 1형 당뇨병환자의 40~50%에서 당뇨병성 신증이 발생된다. 제 2형 당뇨병환자의 경우에는 임상적으로 문제시 되는 당뇨병성 신증 환자는 적게 발생되어 5~10%만 발생된다.

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Colchicine-induced Acute Myopathy in a Renal Recipient (신이식 환자에서 Colchicine에 의해 유발된 급성 근육병증 1예)

  • Kim, Jin-Soo;Shin, Chae-Won;Yang, Huijun;Kim, Jun Soon;Hong, Yoon-Ho
    • Annals of Clinical Neurophysiology
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    • v.10 no.2
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    • pp.112-115
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    • 2008
  • Colchicine is a drug used for the treatment of acute gouty arthritis or various autoimmune diseases. Gastrointestinal adverse effects such as abdominal pain and vomiting are the common side effects of the drug, but rarely myopathy has been reported to occur particularly in renal recipients who were treated concomitantly with immunosuppressants. Herein, we report a case who presented with acute myopathy after treated with colchicine for acute gouty arthritis.

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