• Title/Summary/Keyword: 신경자극

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The effect of low power GaAlAs laser stimulation on anti-nociception and spinal neuronal activity related to pain sensation in the polyarthritis of rats (다발성 관절염 실험동물 모델에서 저출력 GaAlAs 레이저 자극의 진통효능 및 통증관련 척수내 신경세포의 활성변화에 관한 연구)

  • Chang, Moon-Kyung;Choi, Young-Duk;Park, Bong-Soon
    • Journal of Korean Physical Therapy Science
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    • v.10 no.1
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    • pp.180-189
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    • 2003
  • The experiments were designated to evaluate the anti-nociceptive effect of low power laser stimulation on acupoint or non-acupoint using arthrogenic solution induced poly arthritis animal model. Evaluation of potential antinociceptive effect of low power laser on arthritis has employed measurements of the foot bending test, the development of either thermal or mechanical hyperalgesia following the arthritis induction. The analysis of thermal hyperalgesia includes Hargreaves's method. Randall-Sellitto test was utilized for evaluating mechanical hyperalgesia. In addition, the antinociceptive effect of low power laser stimulation on arthritis induced spinal Fos expression was analyzed using a computerized image analysis system. The results were summerized as follows: 1. In laser stimulation on acupoint treated animal, laser stimulation dramatically inhibited the development of pain in foot bending test as compared to those of non acupoint treated animal group and non treated animal group. 2. The threshold of thermal stimulation was significantly increased by low power laser stimulation on acupoint as compared to that of non treated control group. 3. Laser stimulation on acupoint dramatically attenuated the development of mechanical hyperalgesia as compared to that of non treated group. 4. Low power laser stimulation on acupoint significantly suppressed arthritis induced Fos expression in the lumbar spinal cord at 3 week post arthritis induction. In conclusion, the results of the present study demonstrated that low power laser stimulation on acupoint has potent anti-nociceptive effect on arthritis. Additional supporting data for an antinociceptive effect of laser stimulation was obtained using Fos immunohistochemical analysis on spinal cord section. Those data indicated that laser stimulation induced antinociception was mediated by suppression of spinal neuron activity in pain sensation.

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The Comparative Study on the Frequency of Transcutaneous Electrical Nerve Stimulation for Delayed-Onset Muscle Soreness (지연성 근육통에 대한 경피신경전기자극의 주파수별 효과 비교)

  • Park, Hyun-Gun;Lee, Jong-Soo
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.2
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    • pp.63-72
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    • 2013
  • Objectives : The aim of this study was to investigate difference of the effects of transcutaneous electrical nerve stimulation(TENS) with different frequencies in participants having delayed onset muscle soreness(DOMS). Methods : We recruited 36 healthy participants, but 3 of them were dropped out. They were randomly divided into 3groups : 3 Hz TENS(n=11), 100 Hz TENS(n=11) and sham TENS(n=11). DOMS of the both triceps surae muscle induced by repetitive concentric, ecentric exercise. The result measurements were pain perception(visual analogue scale, VAS), mechanical pain threshold(MPT) by pressure algometer, electrical contraction and fatigue by surface electromyography. The measurements were on first visit, before and after treatment except first. This study was prospective, randomized, controlled, single-blinded trial. Results : In 100 Hz TENS group, VAS was significantly decreased during whole session compared with 3 Hz and control group, and after each treatment, too. In 3 Hz TENS group, VAS was significantly decreased during whole session compared with control group, and after 2nd, 3rd treatment, too. In 100 Hz TENS group, MPT increased the most among 3 groups during whole session and after 1st treatment, but there were no statistical significances. Conclusions : Both 3 Hz and 100 Hz TENS improved delayed onset muscle soreness, but 100 Hz TENS group is more effective than 3 Hz TENS group.

Influence of Neuromuscular Electrical Stimulation on MEF2C and VEGF Expression of Neonatal Rat Skeletal Muscle During Suspension Unloading (신경근전기자극이 체중 부하를 제거한 신생 흰쥐 골격근 조직의 MEF2C 및 VEGF 발현에 미치는 영향)

  • Koo, Hyun-Mo;Lee, Sun-Min
    • Physical Therapy Korea
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    • v.14 no.1
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    • pp.28-36
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    • 2007
  • The aim of this study was to identify the effect of suspension unloading (SU) and electrical stimulation upon the development of neonatal muscular system. For this study, the neonatal rats were randomly divided into three groups: a control group, an experimental group I, and an experimental group II. The SU for experimental group I and II was applied from postnatal day (PD) 5 to PD 30. The electrical stimulation for soleus muscle of experimental group IIwas applied from PD 16 to PD 30 using neuromuscular electrical stimulation (NMES), which gave isometric contraction with 10 pps for 30 minutes twice a day. In order to observe the effect of SU and ES, this study observed myocyte enhancer factor 2C (MEF2C) and vascular endothelial growth factor (VEGF) immunoreactivity in the soleus muscles at PD 15 and PD 30. In addition, the motor behavior test was performed through footprint analysis at PD 30. The following is the result. At PD 15, the soleus muscles of experimental group Iand II had significantly lower MEF2C, VEGF immunoreactivity than the control group. It proved that microgravity conditions restricted the development of the skeletal muscle cells at PD 15. At PD 30, soleus muscles of the control group and experimental group II had significantly higher MEF2C, VEGF, immunoreactivity than experimental group I. It proved that the NMES facilitated the development of the skeletal muscle cells. At PD 30, it showed that SU caused the decrease in stride length of parameter of gait analysis and an increase in toe-out angle, and that the NMES decreased these variations. These results suggest that weight bearing during neonatal developmental period is essential for muscular development. They also reveal that NMES can encourage the development of muscular systems by fully supplementing the effect of weight bearing, which is an essential factor in the neonatal developmental process.

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A Study about Sasang Constitutional difference on Autonomous Function after Acupuncture stimulation (침자극 후 사상체질별 자율신경활동의 변화에 대한 연구)

  • Kwak, Chang-Kyu;Sohn, Eun-Hae;Lee, Eui-Ju;Koh, Byung-Hee;Song, Il-Byung;Hwang, Wook
    • Journal of Sasang Constitutional Medicine
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    • v.16 no.3
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    • pp.76-84
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    • 2004
  • 1. Objectives This paper is intended to find out Sasang Constitutional difference on Autonomous Function after Acupuncture stimulation in healthy subjects. 2. Methods of Research Nineteen healthy volunteers(Soyangin 6, Taeumin 7, Soeumin 6) had acupunctured perpendicularly into the Hapkok point(LI4) and the Taechung point(Liv3). Heart Rate Variability, Mean Heart Rate and Blood Pressure were checked 4 times(before and after Acupuncture stimulation) to evaluate Autonomous Function. 3. Results & Conclusions The conclusions were as follows 1. There was no statistically significant Sasang Constitutional difference on sympathetic activity and parasympathetic activity before Acupuncture stimulation. 2. Acupuncture stimulation caused a statistically significant increase in the parasympathetic activity in the whole subject. 3. After Acupuncture stimulation, there was a statistically significant increase in the parasympathetic activity in Soeumin and a tendency of increase in the parasympathetic activity in Soyangin. But there was a tendency of increase in the Sympathetic activity in Taeumin.

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Sinoatrial Reentrant Tachycardia in a Yorkshire Cross Dog (요크셔테리어 잡종견에서 나타난 동방회귀성 빈맥증)

  • Nam, So-Jeong;Hyun, Chang-Baig
    • Journal of Veterinary Clinics
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    • v.25 no.5
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    • pp.391-395
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    • 2008
  • An 8-year-old intact male Yorkshire cross dog (7.5 kg of body weight) was referred with the primary complaint of exercise intolerance and occasional syncope. Initial cardiological examination could not identify any abnormalities except mild mitral regurgitation. Exercise stress test revealed chronotrophic incompetence. Furthermore the 1 hr-digital event recording found the sudden onset of paroxysmal sinus tachycaridas (156-172 bpm) lasting few minutes and stopping abruptly. In addition, the tachycardia terminated by vagal maneuver and verapamil administration. Based on this finding, the case was diagnosed as sinoatrial reentrant tachycardia (SART). The dog was treated with diltiazem and enalapril. Although the dog still has exercise intolerance, no syncope has been observed after medication.

The Effect of Galvanic Vestibular Stimulation on Autonomic Nervous System Response (평류안뜰자극이 자율신경성 반응에 미치는 영향)

  • Moon, Hwa-Young;Kang, Sol;Kim, Hwa-Sung;Soon, Yu-Ri;Huh, So-Young;Lee, Jeong-Woo
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.8 no.2
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    • pp.19-24
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    • 2010
  • Purpose : This study aims to examine the influences of galvanic vestibular stimulation on autonomic reaction of normal adults. Methods : Participants in this research totaled 28 (14 men and 14 women). Galvanic vestibular stimulation was conducted with a binaural electrode configuration for 60 sec. Galvanic vestibular stimulation measurements were conducted with the subjects in a prone position. Measured items included skin conductance, blood flow, pulse rate, and respiratory rate. Measurements were repeated for a total of five times, before application, during application, after application, 5 minutes after application and 10 minutes after application. Results : Skin conductance reaction showed statistically significant differences in changes depending on time after galvanic vestibular stimulation and there were statistically differences in changes of blood flow, pulse rate and respiratory rate after galvanic vestibular stimulation. Conclusion : Blood flow, pulse rate and respiratory rate of autonomic reactions were not influenced by galvanic vestibular stimulation, but skin conductance reaction was influenced by it and it was found that it was reduced during and after stimulation rather than before stimulation. Consequently, it was considered that galvanic vestibular stimulation affected the autonomic reaction.

Effects of Auricular Acupuncture on NADPH-diaphorase Neurons in Brain Cortex of Fasted Rats (이침자극(耳鍼刺戟)이 절식(絶食) Stress로 인(因)한 흰쥐 대뇌피질(大腦皮質)의 NADPH-diaphorase 신경세포(神經細胞)에 미치는 영향(影響))

  • Lee, Jung-hyun;Kim, Ee-Hwa;Lee, Eun-yong
    • Journal of Acupuncture Research
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    • v.18 no.2
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    • pp.79-90
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    • 2001
  • Objective : The aim of the present study is to investigate whether stimulating a specific auricular point(胃點) is effect on suppression of appetite. Methods : This study evaluated the changes of Reduced-Nicotinamide-Adenine-inucieotide-Phosphate-diaphorase(NADPH-d)-positive neurons using a histoehemical method. Staining intensities of NADPH-d-positive neurons were assessed in a quantitative fashion using a microdensitometrical method based on optical density by means of an image analyzer. Results : The results show as follows ; 1. In the RSG/RSA, FRI/FR2, HL, PAR1 area, The optical density of NADPH-d-positive neurons of fasted group was significantly decreased in comparison to fed group. 2. In most cortical area, It was not significant statistically, But the optical density of NADPH-d-positive neurons of fed with auricular acupuncture group was decreased in comparison to fed group. 3. In most cortical area, It was not significant statistically, But fasted with auricular acupuncture group increased the optical density of NADPH-d-positive neurons comparison to fasted group. Conclusions : We conclude that stimulating the specific auricular points is able to effect on NO(Nitric Oxide)-expression in the brain cortex of sprague dawley rats, The results suggest that auricular acupuncture may be useful for controlling obesity.

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Effects of Electroacupuncture on Neuropathic pain in Rats (신경병증성 통증에 대한 전침자극 효과의 연구)

  • Hwang Byung-Gil;Yu Gi-Yong;Kim Ji-Hoon;Park Dong-Suk;Min Byung-Il
    • Journal of Acupuncture Research
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    • v.18 no.6
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    • pp.215-224
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    • 2001
  • Objcetive : Neuropathic pain sometimes arises from a partial peripheral nerve injury. This kind of pain is usually accompanied by spontaneous burning pain, allodynia and hyperalgesia. It has been well known that acupuncture is effective to the pain control from ancient time in Asia. However, it is not clear whether acupuncture can control neuropathic pain. The aim of the present study is to examine if acupuncture stimulation may be effective to the mechanical allodynia in a rat model of neuropathic pain. Methods : To produce neuropathic pain, under sodium pentobarbital anesthesia, the right superior caudal trunk was resected between the S3 and S4 spinal nerves. After the neuropathic surgery, we examined if the animals exhibited the behavioral signs of mechanical allodynia. The mechanical allodynia was assessed by stimulating the tail with von Frey hair (bending force : 2.0g). three or 6 weeks after the neuropathic surgery, acupuncture stimulation was delivered to Houxi (SI 3) as the following parameters (2HZ frequency, 0.07mA intensity and 3msec duration) for 30 minutes. Results : The stimulation of Houxi (SI 3) acupoint relieved the behavioral signs of mechanical allodynia. Conclusion : Our results suggest that acupuncture can control the mechanical allodynia of neuropathic pain.

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Antispastic Effects of Electroacupuncture, TENS and NMEs in Stroke Patient (중풍경직에 전침, TENS 및 신경근 자극기의 효과에 대한 연구)

  • Kim, Yong-suk
    • Journal of Acupuncture Research
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    • v.17 no.2
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    • pp.209-220
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    • 2000
  • Spasticity, an abnormal increase in resting muscle tone, is one of the most common symptoms of stroke, and its management is becoming a major issue in rehabilitation. The aims of this study are to determine the effects of electroacupuncture(EA), TENS and neuromuscular electric stimulation(NMES) on spasticity, as well as the possibility of tissue comliance method as a spasticity scale. 45 stroke patients participated in a study of the effects on hemiplegic spasticity of EA, TENS and NMES. Spasticity was measured by modified Ashworth scale on the upper extremity and tissue compliance measurement, penetration mm/kg, on Susamni(LI10) area at just before and after stimulation, and 30 minutes, 1 hour, 2 hours and 24 hours after stimulation. The acupuncture points were applied to Kokchi(LI11), Susamni(LI10), Hapkok(LI4) and Oegwan(TE5) of the affected limb. The electrodes were placed unilaterally on LI11 to LI10 and TE5 to LI4. EA with biphasic wave, 60Hz, 0.4 msec pulse duration and low intensity was applied continuously for 20 minutes. TENS with high frequency, low intensity was applied. NMES was applied with spasticity program for 20 minutes. Each electric stimulation was done on extensor muscles group of forearm for 20 minutes. EA and NMES groups were found to produce a statistically significant decrease(p〈0.05) of spasticity and these effects lasted up to 30 minutes after stimulation. There was no definite correlation between the modified Ashworth scale and tissue compliance measurement. But tissure compliance method was found to be possible as a quantitative measurement on spasticity. There was no significant correlation between the effects of EA and NMES and the characteristics of patient, but significant correlation between the effects of EA and NMES and the modified Ashworth scale.

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The Effect of Myofacial Release and Transcutaneous Electrical Nerve Stimulation on the Range of Motion and Pain in Patient with Chronic Cervical Neck Pain (만성경부통증 환자에 대환 근막이완술과 경피신경 전기자극 치료가 치료기간에 따라 관절가동범위와 통증에 미치는 영향)

  • Seo, Hyun-Kyu;Gong, Won-Tae;Lee, Sang-Yong
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.11 no.2
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    • pp.1-12
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    • 2005
  • The purpose of this study is compare the effects of two therapeutic processes-i) conservative Myofacial Release Technique along and ii) Transcutaneous Electrical Nerve stimuliation alone - on the increase in the range of motion(ROM) and on the decrease in patient's pain with chronic Neck pain. The subjects of the study were student with choronic neck pain in Daegu health university. Half of them (10) took conservative Myofacial Release Technique along and the others (10) took Transcutaneous Electrical Nerve stimuliation alone. I used 3D Motion analysis. The range of motion (ROM) in six areas-flexion, extension, left lateral flexion, right lateral flexion, left rotation, right rotation-to check the effectiveness of the two combinations of methods, measured pain with visual analogue scale (VAS) to see the effect on pain reduce. Assement was conducted to the groups before the treatment began and affer the four weeks treatment ended. This study shows that both groups demonstrated significant improvement in ROM increase and pain reduction. Flexion ROM increases were significant in MFR and TENS after treatment 2 weeks and 4 weeks. Extension ROM increases were significant in MFR and TENS after treatment 2 weeks. Right rotation ROM was no significant differences were found in MFR and TENS after treatment all weeks. Right lateral flexion ROM increases were significant in MFR and TENS after treatment 3 weeks. Left lateral flexion ROM increases were significant in MFR and TENS after treatment 1 weeks. But the others no significant differences were in MFR group and TENS group during 4 weeks.

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