• Journal of Korean Physical Therapy Science
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• v.2 no.3
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• pp.587-598
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• 1995

The purpose of this study was to test the microcurrent electrical neuromuscular stimulation on muscle soreness, serum creatine kinase levels and force deficits evident following a high-intensity eccentric exercise bout. 10 volunteer male subjects were randomly assigned to a treatment group or to a control group. Exercise consisted of high-intensity eccentric contractions of the elbow flexors. Resistance was reduced as subjects fatigued, until they reached exhaustion. Muscle soreness rating was determined using a visual analog scale. Serum creatine kinase levels were analyzed using a blood sample. Force deficits were determined by measures of maximal voluntary isometric contraction at $90^{\circ}$ of elbow flexion on a Orthotron II dynamometer. Muscle soreness rating, serum creatine kinase levels and maximal voluntary isometric contraction were determined at the before exercise and again at 24 and 48 hours postexericse. Treatments were applied immediately following exercise. The control group subjects rested following their exercise bout. Statistical analysis showed significant increases in muscle soreness rating and significant decreases in maximal voluntary isometric contraction when the before exercise was compared with 24 and 48 hour measures(p<0.01). No significant effects were observed between groups in muscle soreness rating and maximal voluntary isometric contraction(p>0.05). Highly significants differences in serum creatine kinase levels were found using on Analysis of variance(ANOVA) repeated measures between groups for each time cycles(p<0.001). This modality may have benefits when used early stage in the muscle damage.

• Journal of Korean Physical Therapy Science
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• v.2 no.3
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• pp.599-608
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• 1995

If a controlled sensory stimulation is given to the specific receptors, a reflex movement and motor engrams is achieved by the principle of neurophysiology. Based on this theoretical background, we choose 80 healthy person(male 40,female 40) and compare chronaxie of before stimulation with after stimulation. Also we measured chronaxie with same method. Stimulation was applied to the muscle belly by tapping. The results are summarized as follows; 1. The mean value of rheobase measured from the proximal part of upper extremity is 3. 56mA for male, 4.04mA for female. 2. The mean value of rheobase measured from the lower extremity is 4.19mA for male, 4. 37mA for female, which is higher than that of upper extremity for both male and female. 3. The mean value of chronaxie from the proximal part of upper extremity is 0.91msec for male, 0.87 msec for female, which means male is higher than female, and the average is 0.82msec. 4. The mean value of chronaxie from the proximal part of lower extremity is 1.04msec for male, 1.14msec for female, which means female is higher than male. 5. The decrease of rheobase after stimulation is prominent at the triceps brachii for male, biceps brachii for female. 6. The decrease of rheobase after stimulation is prominent at the tibialis anterior for both male and female. 7. The decrease of chronaxie after stimulation is prominent for both male and female at the triceps brachii from upper extremity and at the tibialis anterior from lower extremity for both male and female.

• Science of Emotion and Sensibility
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• v.14 no.2
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• pp.235-244
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• 2011

The purpose of this study is to investigate whether the appropriateness of gustatory features in product design affect product evaluation and accompanied response by using functional magnetic resonance imaging(fMRI). Through the pilot survey, we categorized the product designs into two groups based on the level of the appropriateness. The total of 40 product designs were selected as the experimental stimuli. 15 right-handed participants(mean age = 23.33, SD = 1.7) were scanned with 3T MRI machine(ISOL Tech, Oxford OR63). The experimental stimuli were passively presented inside the scanner. In post scanning session, participants were asked to measure their preference and buying intention to the product designs. The results show that both the preference and buying intention were significantly higher for the high appropriateness condition compared to those of low appropriateness designs. Caudate nucleus and putamen, areas related to the positive reward such as monetary acquisition showed greater activation in response to the designs of high appropriateness condition, compared to the low appropriateness designs.

• Journal of Korean Physical Therapy Science
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• v.2 no.2
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• pp.465-479
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• 1995

We randomly assigned 61 healthy subjects(male 14, female 47) to compare the experimental pain threshold and skin temperature between high mode TENS and burst mode TENS. In this study, 61 subjects were divided into three groups ; high mode TENS(n=20), burst mode TENS (n=20), and control group(n=21). Experimental pain thresholds and skin temperatures were measured before, immediately after cessation of stimulation, and at 30 minutes post stimulation. Stimulation was applied to the dorsal surface of the forearm(L14, LI10). Pain thresholds were measured by chronaxie meter. Skin temperature were measured by electrical digital thermometer. The results are as follows ; 1. There were no statistical difference in the pain threshold and skin temperature at before TENS stimulation among the three groups(p>0.05). 2. The pain threshold and skin temperature in burst mode TENS group was significantly higher and longer effect than that in high mode TENS group and control group(p<0.01). 3. The pain threshold in burst mode TENS group decreased to prestimulation levels by 30 minutes poststimulation. 4. The skin temperature in burst mode TENS group decreased to prestimulation levels by 20 minutes poststimulation. 5. The skin temperature was significantly difference among three group at immediately after, and at 30 minutes poststimulation and the skin temperature in burst mode TENS group was significantely higher than that in two groups(p<0.001). 6. The increasing rate of pain threshold in high mode TENS group after immediately cassation of stimulation was 24.3%(p<0.001). 7. The increasing rate of pain threshold in burst mode TENS group after immediately cessation of stimulation was 93.5% (p<0.001).

• Journal of Biomedical Engineering Research
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• v.30 no.4
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• pp.347-354
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• 2009

For the reliable transmission of meaningful visual information using prosthetic electrical stimulation, it is required to develop an effective stimulation strategy for the generation of electrical pulse trains based on input visual information. The characteristics of neuronal activities of retinal ganglion cells (RGCs) evoked by electrical stimulation should be understood for this purpose. In this study, for the development of an optimal stimulation strategy for visual prosthesis, we analyzed the neuronal responses of RGCs in rd1 mouse, photoreceptor-degenerated retina of animal model of retinal diseases (retinitis pigmentosa). Based on the in-vitro model of epiretinal prosthesis which consists of planar multielectrode array (MEA) and retinal patch, we recorded and analyzed multiunit RGC activities evoked by amplitude-modulated electrical pulse trains. Two modes of responses were observed. Short-latency responses occurring at 3 ms after the stimulation were estimated to be from direct stimulation of RGCs. Long-latency responses were also observed mainly at 2 - 100 ms after stimulation and showed rhythmic firing with same frequency as the oscillatory background field potential. The long-latency responses could be modulated by pulse amplitude and duration. From the results, we expect that optimal stimulation conditions such as pulse amplitude and pulse duration can be determined for the successful transmission of visual information by electrical stimulation.

• Journal of Biomedical Engineering Research
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• v.35 no.6
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• pp.234-241
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• 2014

This study was designed to investigate the effects of stimulation intensity and inter-electrode distance on the parameters of the measured sensory nerve signal. 30 healthy subjects participated in this study. Sensory nerve signals were elicited by four different pulse amplitudes, i.e., 3, 6, 9, 12 mA, with the pulse width fixed at $500{\mu}s$. The sensory nerve signals elicited by the four different pulse amplitudes were measured by four different inter-electrode distances (20, 30, 40, and 50 mm). We extracted four parameters (pulse amplitude, pulse width, pulse area, and latency time from stimulation) from the sensory nerve signals. The measured pulse amplitude and pulse width were increased when the measuring inter-electrode distance was increased while the stimulating pulse amplitude was fixed. The measured pulse amplitude was saturated with the stimulating pulse amplitudes of over 6 mA while measuring inter-electrode distance. Under the same condition, measured pulse width was increased, and sensory nerve signal was initiated early. Sensory nerve signals, specially those of pulse amplitude, were distorted by a differential amplification method that commonly measures the human body signal. The experimental results indicate that the differential amplification method is required to be replaced when measuring nerve signals. Our observations suggested that the hyperpolarization of the action potential of the sensory nerve signal for preventing distortion could be used to clarify the correlation between the parameters of the sensory nerve signals and quantification of sensations.

• Journal of Yeungnam Medical Science
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• v.16 no.1
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• pp.125-130
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• 1999

Congenital myotonia is a hereditary disorder of the skeletal muscle. The most characteristic features of the disease are myotonia and variable muscular hypertrophy. Molecular biologic investigations have revealed that mutations in the gene of the human skeletal muscle chloride ion channel protein are a cause of the disease. The Becker's type congenial myotonia is clinically similar to the autosomal dominantly inherited congenital myotonia (Thomsen's disease). Both disorders are characterized electrophysiologically by increased excitability of muscle fibers. reflected in clinical myotonia. In general, Becker's type congenital myotonia is more severe than Thomsen's disease in muscular hypertrophy and weakness. The authors recently experienced a 25-year-old female patient who has no family-related disease history and who has conspicuous muscular hypertrophy and the stiffness with muscles which occurred from the age of 3 or 4. Clinically she showed the authors a percussion myotonia. On electrophysiological study, exercise and repetitive stimulation of the abductor digiti quinti muscle disclosed a decline in the compound muscle action potential. Biopsy of biceps muscle revealed enlargement of muscle fibers with marked nuclear internalization. After the oral taking the Mexiletine, the patient showed a favorable turn a little with her stiffness of muscles. So we authors are reporting one case of Becker's type congenital myotonia with review of literatures.

• The Korean Journal of Physiology
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• v.21 no.2
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• pp.313-321
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• 1987

To investigate whether the cervical sympathetics contains specific secretory fibers for the salivary glands, reflex salivation was evoked and the role of the sympathetics or the reflex was examined in ketamine-anesthetized cat. Stimulation of the central end of the glossopharyngeal nerve produced a copious secretion from the submaxillary gland and the response was not affected by the section of the cervical sympathetics or by the administration of phenoxybenzamine, whereas the response was abolished by severing the chorda tympani or by the administration of atropine. The salivary response was always associated with an increase in glandular blood flow. Both salivary and blood flow responses were decreased markedly by the superimposed stimulation of the cervical sympathetics or by the administration of norepinephrine. The decreased submaxillary blood flow always preceded the decrease in salivary flow on stimulation of the cervical sympathetics and the decreased blood flow recovered prior to the salivary flow upon cessation of the sympathetic stimulation. The inhibitory effects of the sympathetics and norepinephrine were completely abolished by the pretreatment with phenoxybenzamine. These results indicate that the glossopharyngeal nerve is one of the afferent limbs of the submaxillary salivary reflex and the chorda tympani is the only efferent limb of the reflex pathway. Thus, it is suggested that the cervical sympathetics does not contain the specific secretory fibers for the gland, but plays a role in inhibiting the reflex secretion by decreasing the blood flow to the gland.

• Korean Journal of Cognitive Science
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• v.16 no.4
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• pp.243-254
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• 2005

Pulfrich effect implies the possibility that motion information is processed by the system that processes depth information, and this possibility by supported by various neurophysiological studies. Although Pulfrich effect is processed by the system that processes binocular disparity, the representative depth information, there has not been a psychophysical research to determine the characteristics of the interaction between Pulfrich effect and binorular disparity using a stimulus containing the two information sources. Present research examined the characteristics of the interacation between Pulfrich effect and binocular disparity by nenuring the depth and rotation direction of a rotating cylinder comprised of random dots under two different conditions: 1) consistent rendition where the Pulfrich effect and binocular disparity depth the depth and rotation direction of the cylinder in a consistent manner 2) inconsistent rendition where they did not. , The perceived depth of the cylinder in the consistent condition was larger than that in disparity/Pulfrich effect only condition. Interestingly, the perceived rotation direction of the cylinder in the inconsistent condition was modulated by the relative strength of the disparity and the Pulfrich effect. These results imply that binocular disparity and Pulfrich effect are processed by a common neurophysiological methanism.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.5003-5011
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• 2013

This paper measured whether neural and behavior responses to attention-emotion task were reflected to emotion regulation capacities. For this purpose, Nineteen healthy right-handed graduates participated in the emotion-attention task three times for three days. Before and after the negative and positive video clips were shown, the participants performed emotion-attention task. EEG and response time were recorded during emotion-attention task. There was positive correlation between ERP P100 and P300 component. The larger the P100 amplitudes at the specific positions, the longer the P300 latencies at these same positions during attention-emotion task. The longer the P300 latencies at the specific positions, the longer the delay in response time. Also, there is and individual differences in ERP components and response time during attention-emotion integration task. Individuals who had lower amplitude and shorter latency of ERP showed faster response time during attention-emotion task, regardless of the type of video clips. This characteristic was interpreted to the lower emotional controls due to premature response for target identification.