• Title/Summary/Keyword: 식도암

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Comparative Analysis of Patterns of Care Study of Radiotherapy for Esophageal Cancer among Three Countries: South Korea, Japan and the United States (한국, 미국, 일본의 식도암 방사선 치료에 대한 PCS($1998{\sim}1999$) 결과의 비교 분석)

  • Hur, Won-Joo;Choi, Young-Min;Kim, Jeung-Kee;Lee, Hyung-Sik;Choi, Seok-Reyol;Kim, Il-Han
    • Radiation Oncology Journal
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    • v.26 no.2
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    • pp.83-90
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    • 2008

  • Purpose: For the first time, a nationwide survey of the Patterns of Care Study(PCS) for the various radiotherapy treatments of esophageal cancer was carried out in South Korea. In order to observe the different parameters, as well as offer a solid cooperative system, we compared the Korean results with those observed in the United States(US) and Japan. Materials and Methods: Two hundreds forty-six esophageal cancer patients from 21 institutions were enrolled in the South Korean study. The patients received radiation theraphy(RT) from 1998 to 1999. In order to compare these results with those from the United States, a published study by Suntharalingam, which included 414 patients[treated by Radiotherapy(RT)] from 59 institutions between 1996 and 1999 was chosen. In order to compare the South Korean with the Japanese data, we choose two different studies. The results published by Gomi were selected as the surgery group, in which 220 esophageal cancer patients were analyzed from 76 facilities. The patients underwent surgery and received RT with or without chemotherapy between 1998 and 2001. The non-surgery group originated from a study by Murakami, in which 385 patients were treated either by RT alone or RT with chemotherapy, but no surgery, between 1999 and 2001. Results: The median age of enrolled patients was highest in the Japanese non-surgery group(71 years old). The gender ratio was approximately 9:1(male:female) in both the Korean and Japanese studies, whereas females made up 23.1% of the study population in the US study. Adenocarcinoma outnumbered squamous cell carcinoma in the US study, whereas squamous cell carcinoma was more prevalent both the Korean and Japanese studies(Korea 96.3%, Japan 98%). An esophagogram, endoscopy, and chest CT scan were the main modalities of diagnostic evaluation used in all three countries. The US and Japan used the abdominal CT scan more frequently than the abdominal ultrasonography. Radiotherapy alone treatment was most rarely used in the US study(9.5%), compared to the Korean(23.2%) and Japanese(39%) studies. The combination of the three modalities(Surgery+RT+Chemotherapy) was performed least often in Korea(11.8%) compared to the Japanese(49.5%) and US(32.8%) studies. Chemotherapy(89%) and chemotherapy with concurrent chemoradiotherapy(97%) was most frequently used in the US study. Fluorouracil(5-FU) and Cisplatin were the most preferred drug treatments used in all three countries. The median radiation dose was 50.4 Gy in the US study, as compared to 55.8 Gy in the Korean study regardless of whether an operation was performed. However, in Japan, different median doses were delivered for the surgery(48 Gy) and non-surgery groups(60 Gy). Conclusion: Although some aspects of the evaluation of esophageal cancer and its various treatment modalities were heterogeneous among the three countries surveyed, we found no remarkable differences in the RT dose or technique, which includes the number of portals and energy beams.

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A CASE OF ADENOID CYSTIC CARCINOMA OF THE TRACHEA (기관에 발생한 선낭포성 암 1례)

  • 민헌기;나인국;노영수;임현준
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1991.06a
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    • pp.37-37
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    • 1991

  • 선낭포성 암은 대부분 타액선에 발생하는 질환으로 원발성으로 기관에 발생하는 경우는 매우 드물다. 이는 증상이 없이 서서히 진행할 수 있어 진단이 어렵고 늦어질 수 있으며, 기질적 질환을 발견하지 못하는 경우 기관지 천식으로 진단하에 치료를 하는 경우도 있다. 서서히 진행하기 때문에 치료 후의 판정에도 어려운 점이 있다. 저자들은 2년전 기관지 천식 진단 하에 호흡곤란이 있어 기관절개술 시행 후 기관탈관 곤란증으로 이비인후과에 입원한 례에서 기관에 발생한 선낭포성 암을 후두적출술로 치험하였기에 보고하는 바이다.

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Follow up and Salvage Treatment for Early Laryngeal Cancer (초기후두암의 추적관찰 및 재발암의 구제치료)

  • 이강대
    • Korean Journal of Bronchoesophagology
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    • v.3 no.1
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    • pp.50-60
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    • 1997

  • 조기후두암은 치료 목표는 생명을 구하면서 동시에 후두기능을 최대한으로 보존하는 것이라고 할 수 있는데, 치료자의 철학과 환자의 선호도에 따라 방사선 치료, 레이저 수술 그리고 후두부분적출술 등의 방법이 적용되고 있다. 어떤 치료 방법이던 재발암에 대한 구제치료를 포함하면, 궁극적인 생존율은 거의 비슷하다. 그러므로 일차 치료후 얼마나 적극적으로 환자를 추적관찰하고, 적절한 구제수술을 시행하느냐에 따라 생명의 보존 그리고 재발암에서의 기능의 보존 여부가 좌우된다고 할 수 있다. 향후 보다 체계적인 추적 관찰법과 최소의 환자 부담으로 최대의 성과를 거둘 수 있는 치료방법 이 연구되어져야겠다.

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