• Clinical and Experimental Pediatrics
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• v.45 no.12
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• pp.1546-1550
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• 2002

Purpose : The authors carried out this study to determine the relationship between vigabatrin (VGB) and visual field defect.. Methods : Seventy eight patients older than 8 years who had epilepsy which had developed and been diagnosed, and were receiving add-on therapy, were the subjects of this study. If suspicious results were obtained from the initial test with the Humphrey automatic perimeter, the patient was tested again with the Goldman perimeter. Follow-up examinations were performed on these patients after 6 months. Results : In this study, five of the 78 patients had suspicious primary test results, but upon the second examination they were all found to be normal. Thus there were no patients with visual field defects. Conclusion : VGB is a drug which may cause visual field defects, but in this study no patients presented with this symptom. Instead of limiting the use of VGB due to the adverse effect of visual field defect in the initial treatment of partial seizure and infantile spasm untreatable with other medication, if used with care it may not cause serious problems. Screening for visual defect is recommended, and in patients taking VGB regular examination is necessary.

• Journal of the Korean Institute of Intelligent Systems
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• v.22 no.6
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• pp.694-699
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• 2012

In this paper, semiconductor package inspection results using white light interferometer with large F.O.V., in order to apply semiconductor product inspection process, are shown. Experimental 3D data repeatability test results for the same special bumps of each substrate are shown. Experimental 3D data repeatability test results for all the bumps in each substrate are also shown. Semiconductor package inspection using white light interferometer with large F.O.V. is very important for the fast 3D data inspection in semiconductor product inspection process. This paper is surely helpful for the development of in-line type fast 3D data inspection machine.

• Journal of The Korean Ophthalmological Society
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• v.58 no.3
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• pp.321-326
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• 2017

Purpose To identify the correspondence between the central sensitivity of several visual field (VF) tests and ganglion cell inner plexiform layer (GC-IPL) thickness in early glaucoma patients with parafoveal scotoma. Methods Fifty-seven eyes from 57 patients with glaucomatous optic neuropathy and parafoveal scotoma were analyzed using the standard automated perimetry (SAP) C10-2 test, the SAP C24-2 test, and the frequency doubling technology perimetry (FDT) C24-2 test. The correlation between the VF central sensitivity and the GC-IPL thickness from macular scans via optical coherence tomography was analyzed. Results The central sensitivity was $27.51{\pm}5.43dB$, $27.39{\pm}5.05dB$, and $22.09{\pm}5.08dB$ for SAP C24-2, SAP C10-2, and FDT C24-2, respectively. Mean GC-IPL thickness was $70.2{\pm}8.5{\mu}m$. Using regression analysis, the value of log $R^2$ between the logarithmic central sensitivity and GC-IPL thickness was 0.498, and the linear $R^2$ between the antilogarithmic central sensitivity and GC-IPL thickness in SAP C10-2 was 0.486, and both were statistically significant (p < 0.05). This relationship was stronger in early glaucoma patients compared to late glaucoma patients using SAP C10-2. Conclusions The structure-function relationship between GC-IPL thickness and central sensitivity was better with SAP C10-2, especially in early glaucoma patients, compared to other VF modalities.

• Journal of Korean Ophthalmic Optics Society
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• v.21 no.3
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• pp.253-257
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• 2016

Purpose: To determine whether the distance between objects and the size of object are factors to be able to affect dynamic stereoacuity. Methods: Subjects were 37 adults (26 males and 11 females) with an average age of $23.89{\pm}1.76$. Refractive error was fully corrected for all subjects and each visual acuity of them was over 0.9. Three rods test was performed for measurement of stereoacuity. The viewing angles from left rod to right rod were set $5^{\circ}$, $10^{\circ}$, and $15^{\circ}$ and the rod thickness used 7 mm, 14 mm, and 21 mm, respectively. Stereoacuity was repeatedly measured three times in each test condition at 2.5 m distance, and reported the average value of them. Results: When rod thickness was 7 mm or 14 mm, dynamic stereoacuity decreased as the viewing angle increased, and they were significantly decreased (p<0.01) at viewing angles of $10^{\circ}$ and $15^{\circ}$ as compared with that of at $5^{\circ}$, respectively. When rod thickness was 21 mm, dynamic stereoacuity decreased as the viewing angle increased, especially, that of at $15^{\circ}$ decreased significantly (p<0.01) as compared with that of at $5^{\circ}$. The dynamic stereoacuity depending on the rod thickness have an increasing tendency as the rod thickness increased. Conclusions: The viewing angle between objects and the size of viewing object were factors that affect to dynamic stereoacuity.

• Journal of the Korean Institute of Intelligent Systems
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• v.23 no.4
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• pp.286-291
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• 2013

In this paper, in-line type flip chip bump 3D inspection equipment, using white light interferometer with large F.O.V., which is aimed to be used in flip chip bump test process is developed. Results of flip chip bump height measurement in many substrates and repeatability test results for the bumps in fixed location of each substrate are shown. Test results from test bench and those from developed flip chip bump 3D inspection equipment are compared and as a result repeatability is improved by reducing the impact of system vibration. A valuation basis for the testing quality of flip chip bump 3D inspection equipment is proposed.

• Bulletin of the Korean Space Science Society
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• 2004.04a
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• pp.34-34
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• 2004

국가지정연구실 사업인 "인공위성 및 지구접근천체 감시연구"에서는 2003월 한국천문연구원 전파연구동에 60cm 광시야 망원경을 설치하여 시험가동중이다. 이 광시야 망원경의 광학계는 초점비 F/2.92로 직초점 방식이며 3개의 보정렌즈를 이용하여 보정된 초점면의 시야는 2.7도가 되도록 설계되었다. 독일에서 제작하였으며 광학계를 구동할 마운트는 국내 제작하였다. Apogee사 AP10, FingerLake 사 2K CCD 카메라, Pentax 67사진 카메라와 같은 다양한 관측기기를 이용하여 광학계의 성능을 검사하고 광축조정을 하고 있으며 발생한 문제점을 파악하여 해결하고 있다. (중략)

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.3 no.2
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• pp.169-174
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• 2000

Purpose: Previously reported ocular complications of interferon alfa administration are extremely rare. We experienced a 15-year-old boy with chronic hepatitis B who developed glaucoma after interferon alfa therapy. The purpose of this prospective study was to evaluate the possible development of glaucoma after interferon alfa therapy for chronic hepatitis B. Methods: Nine patients with chronic hepatitis B who visited Inha university hospital between February 1998 and July 1999 received interferon alfa therapy. We measured visual acuity, intraocular pressure, C/D ratio, and visual field examination at pre-interferon therapy, three and six months after therapy, respectively. Results: The total number of patients was 9 (4 boys and 5 girls). Mean age was $11.7{\pm}4.1$ years. The duration of therapy was 6 months and mean dosage of interferon was 5 million units. Compared with visual acuity, intraocular pressure, and C/D ratio at pre-therapy, those parameters at 3 months and 6 months after therapy showed no significant differences and none showed visual field defect after therapy. Conclusion: Our prospective study showed no evidence of development of glaucoma after interferon therapy. However, it is necessary to be concerned about the possibility of developing glaucoma or other ophthalmologic diseases after interferon therapy in chronic hepatitis B.

• Investigative Magnetic Resonance Imaging
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• v.3 no.2
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• pp.173-178
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• 1999

Purpose : To evaluate the usefulness of functional MRI (fMRI) of visual cortex in patients with ischemic infarction in the occipital lobe. Materials and Methods : Four patients with the symptoms and signs of visual cortical ischemia were included. Functional MRI was performed by 2D-FLASH technique with the parameter of 90/56msec TR/TE, $40^{\circ}$ flip angle, $240{\times}240{\;}FOV,{\;}64{\times}128$ matrix number, 8.32 seconds acquisition time, 8mm slice thickness. An axial slice including both visual cortices was selected and alternative activation and resting of the visual cortex was performed using red color photostimulator. all patients undertook visual field test, and vascular abnormality was examined by MRA (n=4) and DSA (n=2). fMRI results were compared with the results of a visual field test, conventional MRI and cerebral angiography. Results : On fMRI, decreased activity of the visual cortex was found in the occipital lobe corresponding to stenosis of the posterior cerebral artery or its branch noted on angiogram. However, 2 of 4 patients showed no abnormal findings on conventional MRI. Visual field defect was noted in 3 patients, one and of whom showed no abnormality on conventional MRI and diffusion-weighted image, but revealed decreased activity in the corresponding visual cortex on fMRI. Conclusion : fMRI may be a sensitive method for detection of the status of decreased blood flow or vascular reserve which other methods can not.

• Proceedings of the KSLP Conference
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• 1997.11a
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• pp.267-267
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• 1997

후두스토로보스코피는 성대의 기본주파수에 따라 발산되는 광원에 의해 성대의 움직임을 시각적으로 평가할 수 있게 하여 현재 널리 사용되고 있는 검사방법이지만, 이 검사로는 연속적인 성대의 움직임을 한 시야로 확인할 수 없고 또 정량화 할 수 없다는 단점이 있다. (중략)

• Journal of Korean Society of Transportation
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• v.19 no.1
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• pp.139-148
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• 2001

본 연구는 교통사고 야기 자들의 운전정밀적성검사기록과 해당 교통사고기록을 비교하여 특정 운전적성상의 결손이 교통사고와 특정유형의 교통사고에 미치는 영향을 계량적으로 분석하는 것을 목적으로 하였다. 본 연구를 위하여 우리나라에서 가장 빈발하는 인적요인에 의한 교통사고 유형 중에서 교통상충이 빈발하는 지점에서 발생하는 차-대-차 사고를 조사분석대상으로 삼았다. 이와 같이 분석대상사고를 선정한 이유는 교통상충이 교통사고로 발전하는 과정에서 사고 제1당사자의 운전적성의 역할을 파악하고자하는 목적에서이다. 따라서 본 연구의 대상이 되는 교통사고 유형을 1. 교차로 진입부에서의 추돌사고, 2. 교차로내 충추돌사고, 3. 단일로상의 추돌사고로 선정하였다. 판별력이 의문시되는 4개 항목을 제외한 조사분석결과에서 하나의 항목을 제외하고 사고 야기자와 일반인의 운전적성상에 통계적으로 분명한 차이가 있으며 각 항목의 결손자 집단에서의 사고자 비율이 일반운전자 집단에 비해 교통사고를 경험한 확률이 2배 내지 4배 가량 높았다. 또한 특정 유형 사고 야기자와 사고 야기자 전체, 일반운전자 집단간 비교에서도 항목별 결손율이 분명한 다른 형태를 갖고 있다는 사실을 확인했으며, 특정유형의 결손(조합)자 집합에서 특정 교통사고 유형을 야기시켰을 확률이 일반인 집단에 비해 많게는 13배 적게는 3, 4배 정도 높다고 추정되었다.