• Clinical and Experimental Pediatrics
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• 제52권4호
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• pp.471-475
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• 2009

Purpose : Mitochondrial disorders are a clinical entity characterized by diverse symptoms and signs of involvement of various systems. Furthermore, the disorders are known to show ophthalmologic manifestations as well as neurological findings. Visually evoked potential is a sensitive measure to check the integrity of the visual pathway. In this study, we have investigated the value of visually evoked potential in mitochondrial disorders with respiratory chain defects. Methods : Nineteen patients diagnosed with mitochondrial respiratory chain complex I defect as confirmed by spectrophotometric enzyme assay in muscle samples were enrolled for this study. The patients underwent a visually evoked potential study. We classified the results into four groups and compared these with clinical ophthalmologic findings. Results : Among the 19 patients, 14 showed abnormal visually evoked potential findings. Seven patients showed abnormal clinical ophthalmologic findings. All patients with abnormal ophthalmologic findings showed abnormal visually evoked potential findings. Among the 12 patients with normal ophthalmologic findings, seven showed abnormal results in visually evoked potential. Conclusion : Visually evoked potential study could be used as an effective screening tool for mitochondrial disorders to detect ophthalmologic and neurological abnormalities.

• Archives of Plastic Surgery
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• 제34권5호
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• pp.663-666
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• 2007

Purpose: Autologous fat injection into the facial area is a frequently used technique in aesthetic plastic surgery for augmentation of the soft tissue. Fat injection is a very safe procedure because of the advantage of being autologous tissue. Minimal foreign body reaction or infections are noted after fat injection. However, there may be some complications including those as severe as blindness. There have been some case reports on visual disturbances after autologous fat injection reported in the literature. Methods: A 21-year-old female patient underwent autologous fat injection into left eyebrow area to correct depression of soft tissue. Immediately after injection of autologous fat, she complained sudden visual loss on the left eye. She had come to our emergency room and ophthalmologic evaluation showed that the patient could only recognize hand motion. There was no abnormality of the optic nerve on magnetic resonance imaging. Suspecting an ischemic optic neuritis from fat embolism of the central retinal artery, the patient was treated conservatively with occular massage, antiglaucomatic agent, anti-inflammatory drugs and antibiotics. Visual field examination showed visual defect of half the lower hemisphere. Results: While maintaining antiglaucomatic agents and non steroidal anti inflammatory drugs, fundoscopic examination showed no abnormalities on the second day of admission. Visual field examination showed an improvement on the fourth day along with decreased eyeball pain. Significant improvement of vision was noted and the patient was discharged on the fifth day of admission. The patient was followed-up 2 days afterwards with improved vision and visual field defect. Conclusion: We describe an unusual case of sudden unilateral visual disturbance following autologous fat injection into periorbital area.

• Journal of the Korean BIBLIA Society for library and Information Science
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• 제26권4호
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• pp.283-304
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• 2015

The purpose of this study was to identify Web accessibility issues of healthcare websites of the Korean government and public agencies by evaluating these websites' accessibility in accordance with the Korean Web Contents Accessibility Guideline. This study conducted both automated and expert testing to assess the accessibility of a total of 27 health-related websites. The results of the assessment which was conducted in two stages indicated that institutions such as the National Hospital and National Rehabilitation Center demonstrated almost no Web accessibility error. In addition, the Korea Health Insurance Review and Assessment Service, the Ministry of Health and Welfare, the Health Services Agency, the Ministry of Food and Drug Safety, and the Korea Medical Dispute Mediation and Arbitration Agency attained very high web accessibility. However, the results of an expert evaluation highlighted that there were considerable errors in providing appropriate alternative text, which was not found in the automated test, and the color contrast of the text content did not comply with Web accessibility standard. Therefore, these websites did not support web accessibility for the sight-impaired. Furthermore, the present study found that it was difficult to deliver accurate information to users due to errors in the default language display and markup, and also, issues of skipping repeated content, content linearization, and compliance with keyboard use were considered as challenges that might arise for people with sight, cognitive and mobility impairments with respect to Web accessibility. It is the first study that evaluated accessibility of healthcare websites of the Korean government and public agencies based on the Korean Web Contents Accessibility Guideline. The present study made a contribution to research on Web accessibility by conducting expert testing, which provided a more complete assessment that identified the degree and specific issues of accessibility errors when compared to automated testing.

• Journal of Korean Ophthalmic Optics Society
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• 제19권2호
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• pp.279-284
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• 2014

Purpose: This study will be a basic research providing data which can reduce eye strain using monitor and electric media by measuring legibility of text color on monitor. Methods: Total experimental subjects who don't have color anomaly and best corrected visual acuity was over 1.0 were 50 and their mean age was $22.83{\pm}1.47$. Reading speed test were carried out with 163 words and subjects who could read over 123 words were selected for legibility examination. Monitor background color was white and letter colors were black, blue, red, and yellow for the legibility examination. Results: In case of text color of black, blue, red, and yellow, Event duration(sec) was measured to 41.89, 42.89, 45.32, and 56.28, respevtively, and reading error (number) was measured to 1.94, 2.74, 3.36, and 5.14. Average of fixation duration(sec) was measured to 0.25, 0.26, 0.27, and 0.32. Conclusions: In this paper, event Duration, reading error and average of fixation duration which can measure the legibility was reduced in a sequence of black blue, red, and yellow.

• Journal of Korean Ophthalmic Optics Society
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• 제16권4호
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• pp.433-438
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• 2011

Purpose: To investigate the proper distance from patient to target when measuring refractive error using open view target type auto-refractor(OVTAR), it was compared refractive errors between by OVTAR using N-vision-K5001 auto-refractor and internal fixation target type auto-refractor(IFTAR) using Canon auto-refractor. Methods: 21 subjects(42 eyes) aged 22.2(${\pm}$3.4) years old who had over 1.0 of corrected visual acuity and no ocular disease were participated for this study. Noncycloplegic measurements of refractive error were performed using a IFTAR(RK-F1, Canon, Japan) and an OVTAR(N-vision-K5001, Shin-nippon, Japan). The distances from subjects to targets in using the open the view target type auto-refractor were 1 m, 3 m, 4 m and 6 m. The refractive errors were compared between by IFTAR and by 1 m, 3 m, 4 m and 6 m target distances respectively using OVTAR. Results: At 1 m fixation distance the mean of refractive errors for total subjects was not significantly different between by OVTAR(-2.75${\pm}$1.84 D) and by IFTAR(-2.95${\pm}$2.04 D)(p=0.06). However at 3, 4 and 6 m fixation distance refractive errors by OVTAR were significantly lower myopic refractive errors than by IFTAR(p<0.05). Conclusions: The distance from subject to fixation target is needed over 3 m for the measurement of refractive error using OVTAR even not to 5~6 m distance.

• Journal of Korean Ophthalmic Optics Society
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• 제14권2호
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• pp.41-46
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• 2009

Purpose: Stereopsis is one of primary characteristics for assessment of binocular function. The purpose of this study was to determine the possible relationship between the degree of exophoria and stereoacuity at near. Methods: 110 exophores (male n=71, female n=39, mean $age{\pm}SD=11.30{\pm}1.47$ years) without amblyopia, strabismus, and ocular and systemic pathology were studied. Subjects were also excluded if they had visual acuity poorer than 0.8 in either eye or vertical phoria greater than 1 prism diopter. Clinical tests were performed for near phorias by von Graefe technique using a Digital Refractor (CDR-3100, Huvitz, Korea) with chart (Predio CDC-4000, Huvitz, Korea), and for stereoacuity using the Titmus fly. Results: A one-way analysis of variance revealed that mean values of the stereoacuity classified according to the degrees of the exophoria were not significantly different (p>0.05). Conclusions: Based on the result of this study, it was found that there was no relationship between the degree of exophoria and stereoacuity.

• Journal of Korean Ophthalmic Optics Society
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• 제18권1호
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• pp.45-51
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• 2013

Purpose: This study was performed to provide indicator of expected aniseikonia by correcting refractive error and to investigate influential factors on aniseikonia. Methods: 20 college students (14 males, 6 females, a mean age of $22.50{\pm}2.72$ years) were selected as subjects whose refractive error with spherical equivalent were within ${\pm}0.50$ D, corrected visual acuity were more than 1.0, and aniseikonia values by AWAYA were less than 1%. After correcting refractive error with spectacles in anisometropia induced by wearing contact lens on their dominant eye or non-dominant eye, practical measured values of aniseikonia were compared with theoretical expected values of it by the formula of spectacle magnification. Results: Practical measured values were higher than theoretical expected values in induced aniseikonia over the whole range of diopter of wearing contact lens. And there was higher measured value of aniseikonia in case of higher diopter of wearing contact lens to induce anisometropia and correcting refractive error with spectacles of (+) diopter after wearing contact lens of (-) diopter to induced anisometropia in dominant eye of women. Conclusions: It is considered that dominant eye plays more important role for visual function in induced aniseikonia and factors such as the induced eye of aniseikonia, the diopter of wearing contact lens, and gender have influenced on aniseikonia.

• Journal of Korean Ophthalmic Optics Society
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• 제18권1호
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• pp.37-43
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• 2013

Purpose: The present study was conducted to investigate whether the directions of eye movement in playing computer games for certain period affected the change of near point of convergence (NPC) and fusional reserve (FR) or not. Methods: Total 40 subjects in 20s who have the visual acuity of 1.0 or higher without any ocular disease and accommodative dysfunction were asked to successively play computer games. After the subjects were moving eyes in horizontal and vertical directions for 40 and 90 minutes, their horizontal fusional reserves, vertical fusional vergence and near point of convergence were measured. Results: The near point of convergence showed a tendency to be receded after computer gaming in the horizontal and vertical directions, and both of horizontal and vertical fusional reserves were significantly reduced. The range of declined fusional reserves and receded near point of convergence after computer gaming for 90 minutes was smaller than those after computer gaming for 40 minutes. The change of binocular vision was affected by the horizontal eye movement rather than the vertical movement when analyzed by the direction of eye movement. Conclusions: This study revealed that the change in FR and NPC was different along with dominant direction of eye movement during visual display terminal (VDT) tasks. Therefore, the adjustment of VDT working time is required to prevent the dysfunction of binocular vision according to the dominant direction of eye movement during VDT task.

• Journal of Korean Ophthalmic Optics Society
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• 제7권2호
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• pp.67-71
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• 2002

To investigate the ametropia and refractive error of 364 ametropic eyes en the 182 high school students in Jeonbuk provicne, the visual acuity test was performed by the object and subject method. The results were as follows. 1. The eye types were 85.7% positive for myopia, 6.6% for emmetropia and 7.6% hyperopia, respectively. 2. The abnormal refraction eyes were 30.8% positive for simple myopia, 58.5% for myopia compound astigmatism, 7.5% for myopia simple astigmatism, and 1.8% for simple hyperopia, 1.3% for hyperopia compound astigmatism, 1.9% for hyperopia simple astigmatism, respectively. 3. The axes of astigmatism were 78.7% for astigmatism with-the-rule, 13.9% for astigmatism against-the-rule, 7.4% for astigmatism oblique, respectively. 4. As for the astigmatic power, the 0.50 < cylinder < 1.00dptr was 60.0%, the 1.00 < cylinder < 2.00dptr was 29.2%, and anything over the 2.00cylinder dptr was 10.8%. 5. As for the equivalent spheric power of myopic abnormal refraction eyes, the -0.50 < spheric equivalent < -2.00 diopter was 64.6%, the -2.00 < spheric equivalent < -6.00 dptr was 29.1% and anything over the -6.00 dptr was 6%. 6. The equivalent spheric power of hyperopic abnormal refraction eyes was 50% anything under 2.00diopter and 50% for anything over the 2.00diopter.

• The Journal of Korea Assosiation for Disability and Oral Health
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• 제6권2호
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• pp.94-98
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• 2010

Axenfeld-Rieger syndrome is a rare autosomal dominant disorder characterized by various ocular and extraocular malformations. The incidence of Axenfeld-Rieger syndrome has been estimated to be 1 per 200,000. The syndrome is characterized by short body stature, delayed bone age, and deficient or arrested development of neural crest cells involving the anterior chamber of the eyes, facial bones, teeth, periumbilical skin, and cardiovascular system. This is a case of a 6 year-old girl, who came to the department of the pediatric dentistry, Yonsei University Dental Hospital, for evaluation and treatment of multiple congenital missing permanent teeth. The patient presented typical dental, craniofacial, and systemic features of Axenfeld-Rieger syndrome, such as glaucoma, oval pupil, heterochromatic iris, umbilical hernia, and delayed bone age. On the panoramic view, 3 primary teeth were missing and 13 permanent tooth germs were absent. On the lateral cephalograph, underdevelopment of the maxilla and normal growth pattern of the mandible were confirmed. Periodic dental follow-up is planned for evaluation and interceptive treatment of her dental and craniofacial problems. Denture or removable space maintainer with a pontic is considered for esthetic and functional restoration. In addition, orthognathic surgery is also planned in future to prevent further midfacial skeletal deformation. Early diagnosis of Axenfeld-Rieger syndrome is very important to prevent exacerbation of complications, such as glaucoma and skeletal deformities.