• The Journal of Korean society of community based occupational therapy
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• v.8 no.2
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• pp.29-37
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• 2018

Objective : Sleep disorder caused by stress or disease to elderly currently. We tried to make clear constant exercise according to exercise intensity would have effect on sleep disorder in elderly using EEG and melatonin. Methods : Thirty subjects were over 65 years old who lived a senior facility in some parts. They were able to communicate and understand the purpose of the study. They also expressed their intension to participate actively in experiment. They should have alert consciousness and orientation about time, place, and people. Sleep disorder was assessed via below 6 hr total sleep time and Pittsburge Sleep Quality Index, which was satisfied with both of criterion at the same time. Exercises composed of low intensity walking, moderate aerobic exercise, and high intensity resistance strength. We used QEEG 8-System (LAXTHA Inc. KOREA) to check wave type and Polysomnograpy (Compumedics, Australia) to test quality of sleep. and Histologic features were observed by TTC (triphenyltetrazolium chloride) staining and H & E (Hematoxylin & Eosin) staining. Results : There was a significant sleep index and change of melatonin after aerobic exercise. There was a significant SOL, S1, S2, and SWS in aerobic exercise, but there was a significant SWS in walking and resistance strength. There was a significant change of delta wave especially in frontal and temporal region between exercises. Conclusion : They had different effects according to type of exercise, when elderly who have chemical, behavioral change of circadian rhythms did exercise consistently. Aerobic exercise had more effect on sleep disorder than other exercise. Therefore, we may supply proper exercise to elderly and high quality of life.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.11 no.1
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• pp.52-57
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• 2005

Objectives : Recurrent pregnancy loss occurs in approximately 0.5-3% of women. There are many studies concerning immunological factor recently. Therefore, aim of this study is to examine the latest trend of researches concerning recurrent pregnancy loss, and controlled experiment on animals about antiphospholipid antibody. Method : We referred Pubmed site by using searching word of 'recurrent pregnancy loss' (Limits : 2000.1-2004.3, animal) Results and conclusions : 1. We searched 29 papers. Immunological factor : 18 ( about antiphospholipid antibody : 10 ), Chromosomal abnormality : 6, The others : 5 2. In five papers about controlled experiment on animals, (1) Materials : 8-12 weeks old mice / 11.5-day old-rat embryos / New Zealand rabbit (2) Inductions : inject intraperitoneally with human IgG containing antiphospholipid antibodies / culture in a solution of 1 ml medium which contained IgG purified from sera of women / inject intradermally with cardiolipin (3) Treatments : inject intraperitoneally with complement component before / culture in a solution of 1 ml medium which contained IgG purified from sera of women with SLE and RPL or from healthy women / inject intradermally with TFX, 0.9% NaCl (4) Measurements : weight fetuses and placentas, calculate frequency of fetal resorption / after culture, examine the embryos / examine platelet counts, APTT and numbers of live and dead newborns, resorbed fetuses, body mass, newborn viability and survival rates.

• Clinical and Experimental Reproductive Medicine
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• v.18 no.1
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• pp.113-120
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• 1991

Etiologic classification was performed in 155 patients with recurrent spontaneous abortion history. The incidence was 9.3% among 1658 pregnant women at Hanyang university hospital during the same period. In etiologic classification, 37 cases of on-going patients for diagnostic evaluation were excluded. Of the remained 118 patients, the patients with unknown etiology were 32 cases (27.1%), and 86 cases were classified into each etiologies using appropriate diagnostic modalities. Anatomic causes were the largest etiology, which revealed 46.6% (55 among 118 patients). The next etiology was immunologic cause, which revealed 24.6% (29 patients). Of the 86 patients who have at least one cause, 40.7% (35 among 86) have two or more etiologies. Furthermore, six cases (7%) have 3 combined etiologies. The uterine synechia and/or incompetent internal os of the cervix, namaly anatomic causes, revealed highest combination ratio than other etilogies. The popular abortion technique in Korea, D&C, seems to be main factors for these anatmic causes. The combined causes rather than single cause of recurrent spontaneous abortion were unique situation in Korea especially with anatomic etiologies. From this point of view, we think anatomic etiologies should be rule out first in the evaluation of the patients. For this purpose, we believe hysteroscopy would be helpful as a diagnostic work-up and treatment modality in the management of recurrent spontaneous abortion patients in Korea.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.105-105
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• 2002

염색체의 구조적 이상으로 인한 습관성 유산과 기형아의 출산을 예방하기 위해 착상전 배아에서 할구를 분석하여 정상적인 핵형을 가진 배아만을 이식하는 착상전 유전자 진단 (preimplantation genetic diagnosis, PGD)의 성공적인 임상 적용이 보고되고 있으며, 그 적용 범위가 확대되고 있다. 그러나 일반적인 간기의 핵상을 이용한 PGD에서는 형광직접보합법 probe의 제약으로 보인자와 정상적인 핵형을 구분할 수 없는 단점이 있다. 따라서 본 연구에서는 보다 정확한 PGD를 위해 생쥐 배아를 이용하여 분리한 할구에서 중기 염색체상을 획득하기 위해 미세소관 (microtubule) 형성 저해제를 처리하였으며, 이를 통해 확립된 방법을 인간의 PGD에 적용하고자 하였다. 과배란이 유도된 ICR 생쥐에서 4- 또는 8-세포기 배아를 수획하여 colcemid, nocodazole, vinblastine을 각각 0.1, 0.5, 1.0, 5.0$\mu$M을 처리하고, hoechst 33342로 염색하여 핵상을 관찰하여 최적의 농도를 결정하였다. 또한 각 미세소관 형성 저해제를 혼합 처리하여 가장 높은 중기 염색체상을 획득할 수 있는 혼합 처리를 결정하였다. 이렇게 결정된 혼합 처리 방법을 인간의 체외 수정 및 배아 이식술에서 획득된 3PN 배아에 처리하여 중기 염색체를 획득하였다. Colcemid, nocodazole, vinblastine 모두 1 $\mu$M이 최적 농도임을 확인할 수 있었다 (각각 96.3%, 92.0%, 98,4%). 미세소관 형성저해제를 혼합 처리하였을 경우 nocodazole과 vinblastine (각각 1$\mu$M)을 혼합 처리했을 때 중기 염색체 획득률(97.3%)이 가장 높았다. 인간의 3PN 배아에 1$\mu$M의 nocodazole과 vinblastine을 혼합 처리한 후, 113개의 할구를 분석하여 44개(38.9%)의 할구에서 중기 염색체를 확인할 수 있었다. 본 실험 결과를 통해 중기 염색체를 획득하기 위하여 미세소관 형성 저해제를 처리하는 방법은 생쥐의 배아에서는 효과적이지만, 인간의 배아에서는 그 효율이 다소 낮음을 알 수 있었다. 그러나 이 방법을 개선하여 인간의 할구에서 중기 염색체의 획득률을 높이고, 이를 염색체의 구조적 이상에 대한 착상전 유전자 진단에 적용한다면, 보인자와 정상의 핵상을 구분하여 정상의 핵상만을 갖는 배아의 이식을 통하여 더욱 정확한 착상전 유전자 진단을 시행할 수 있으리라 사료된다.

• The Journal of Korean Medicine
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• v.16 no.2 s.30
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• pp.115-133
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• 1995

In the Oriental Western Consideration of Habitual Abortion, the result of this study is summarized as follows: 1. Habitual abortion means repetition of Tatae(abortion within 3 months), Sosan(abortion after 3 months), and Bansan(abortion after 5 months), as it agrees with Hoaltae, Sutatae and Nuing-Nuta in oriental medical science. 2. Frequency in Occurrence of habitual abortion is about 0.2-0.4%> in the whole pregnancy and the Ratio of Risk increases according to frequency and age increase. 3. Generally, the cause of habitual abortion is due to the cause of the mother. Therefore, diagnosis and treatment of before-childbirth are needed, and 'measures taken to prevent abortion' is in use to improve the condition of health of before-childbirth in oriental medical science. 4. The 50-60% of early abortion is due to the heterochromosome and the ratio of risk of habirual abortion is hightest in heterochromosome. 5. The causes of habitual abortion are summarized as vital energe and blood weakness. impairment of Chong and Ren, aflection by exopathogen, fever caused by blood deficiency. weakness of the spleen and the stomach, excess of seven emotion. excess of a sexual desire and injury of a contusion and also the treatments are summarized as invigorating qi (vital energy) and enriching the blood, reducing fever and enriching the blood, reinforcing the spleen, tonifying the Chong and Ren, the practice of a sceticism, psychological peace in oriental medical science. 6. The approch of modem oriental medical science is based on diagnosis and treatment based on 'over all analysis of symptoms and signs' of traditional oriental medical science. it goes abreast with diagnosis of western medical science, and it can be expected mare inclusive effect of treatment because 'Acupuncture for prevent abortion', 'Acupuncture with the needle warmed by burning moxa', and so on being developed except medicinal therapy.

• The Korea Journal of Herbology
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• v.33 no.4
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• pp.87-93
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• 2018

Objectives : The prevalence of infertility is reported to be 23.3%, which is a serious social problem. Habitual abortion is one of the important complications during pregnancy. The purpose of this study is to help the treatment of habitual abortion by observing and reporting the process in which four women who did not have children due to habitual abortion make healthy birth through treatment. Methods : We administered Jokyungjongok-tang gamibang as a herbal medicine treatment method and treated with acupuncture, moxibustion and uterine steam treatment. Treatment was done once or twice a week but it was also varied depending on the patient's circumstances. The herbal medicines were taken 30 minutes after meals and 3 times a day. While taking the Korean medicine, they were prohibited from eating flour, pork, liquor, tobacco and coffee. Patient status was assessed by consultation through pulse, tongue and abdomen. A detailed questionnaire was performed for each treatment. In some cases, they have tested hormone levels at the hospitals to know ovulation dates. The diagnosis of pregnancy was confirmed by ultrasonography at hospitals and the treatment for habitual abortion was judged based on healthy birth. Results : As a result of herbal medicine, acupuncture, moxibustion and uterine steam treatment, the coldness of the body became weak, the fatigue decreased and the digestive condition gradually began to improve. The bad condition of the uterus caused by the repeated administration of heritage has been improved with Boheosaenghwa-tang gamibang. After administration of Jokyungjongok-tang gamibang, they became pregnant and overcame the condition of addictive abortion and gave birth to healthy children. Conclusion : Jokyungjongok-tang gamibang is effective in overcoming the symptoms of habitual abortion and giving birth to a healthy child for a woman who had no children due to her habitual abortion

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.3
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• pp.62-77
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• 2023

Objectives: The purpose of this study is to investigate the domestic study trends on habitual abortion treated with Korean medicine. Methods: We searched the studies on habitual abortion treated with Korean medicine via searching 5 Korean web databases. After searching studies, we analyzed 7 studies selected according to the selection and exclusion criteria. Results: Of the seven selected studies, five case-reporting studies and two retrospective chart analysis. The most applied intervention for habitual abortion was herbal medication. All patients took herbal medicine before pregnancy, and Seunggum-dan was widely used. 66.3% of pregnant patients after treatment took herbal medicine after pregnancy, and Anjeonyichen-tang was the most widely used. As a result of analyzing retrospective chart analysis studies, whether the patient's age was 35 years or older has a significant impact on the success rate of Korean medicine treatment. Conclusions: This study has provided a basis for using Korean medical intervention in the treatment of habitual abortion in clinical practice. In order to provide a more high-quality basis, reliable follow-up studies related to the effectiveness and stability of Korean medicine treatment for habitual abortion should be conducted in the future.

• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.95-104
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• 2009

This study was carried out through the investigation of Oriental and Western medical literature and we was discovered these conclusions about the etiology, treatment, prescription of habitual abortion. The result of this study were as follows : 1. The habitual abortion does agree with 'Hwaltae(滑胎)' and means that spontaneous abortion repeats three times or more. 2. The etiology of habitual abortion is divided 'Deficiency of kidney'(腎虛), 'Deficiency of vital energy and blood'(氣血虛弱), 'Deficiency of yin'(陰虛), 'Clotted blood'(瘀血). 3. By means of cause, the treatment of habitual abortion was mainly made use of 'Tonifying kidney and promoting spleen'(補腎健脾), 'Invigorating vital energy and nourishing blood'(補氣補血), 'Supplementing yin fluid and alleviating fever'(滋陰淸熱), 'Resuscitating blood and removing clotted blood'(活血祛瘀). 4. By means of cause, the prescription of habitual abortion was frequent made use of Bosingochunghwan(補腎固沖丸), Bosingotae$\breve{u}$m(補腎固胎飮), Taesanbans$\breve{o}$ksan(泰山磐石散), $Ch\breve{o}ng\breve{u}mboinghwan$(千金保孕丸), Agyotang(阿膠湯), Gungguibojungtang(芎歸補中湯), Taewon$\breve{u}$m(胎元飮), Gotaej$\breve{o}$n(固胎煎), Baekchulj$\breve{o}$n(白朮煎), Sas$\breve{o}$ngsan(四聖散), Gyegibokryonghwan(桂枝茯苓丸), $Dangguich\breve{o}ng\breve{u}mtang$(當歸千金湯). 5. The Western medical etiology of habitual abortion(recurrent spontaneous early pregnancy loss) is divided Genetic factor(Chromosome aberration), Anatomical deformity, Endocrinologic disorder, Infection, Immunologic factor, Unknown factor(Others).

• Journal of Digital Convergence
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• v.18 no.7
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• pp.405-410
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• 2020

Fashion is a visual means of expressing identity, position, marital status, personal inclination, etc. along with beauty, and it is an important practical cultural heritage that can infer past lifestyle habits. In modern society, fashion such as women's suits, high heels, hats, gloves, handbags, necklaces, etc., as well as beauty such as hair, make-up and nail art. It is a model of innovative women's prize and presented a sample of femininity that responds to the radical development of science and technology in the 21st century. Therefore, it is a driving force for a genuine gender equality society. It serves as a stepping stone for futuristic future design. This study, which analyzed the factors of women's sexuality from the viewpoint of beauty college students in the fashion style of the newcomers, makes it possible to present a sample of women' s sexuality that establishes constructive self - help theory. It is thought that a solid foundation of femininity will be provided.

• Korean Journal of Food Science and Technology
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• v.36 no.5
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• pp.779-783
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• 2004

New food ingredient was developed to eradicate and protect against re-infection of Helicobacter pylori in fermentation broth of lactic acid bacteria (LAB) showing antimicrobial activity against pathogenic microorganisms such as H. pylori and Listeria monocytogenes. LAB strain CBT SL4 was identified as Pediococcus pentosaceus by 16S rDNA sequencing and its culture broth showed antimicrobial activity of 800 AU/mL against H. pylori in optimized fermentation process. Using thin layer concentration system and spray-typed fluid bed drier system, concentrated powder product showing activity of 12,800 AU/g was harvested. Product showed eradication and protection activities against H. pylori infection on feeding test (50 AU/day) using Mongolian gerbil infection model. After 4 weeks therapy of 8,000 AU/day, ${\Delta}13CO_2$ level (DOB30) decreased about 40% in urea breath test on patient with H. pylori infection. Result show concentrated culture product of P. pentosaceus CBT SL4 has eradicating and protecting activities against H. pylori infection and can be used as food-active ingredient for prevention of gastric and duodenum ulcer caused by H. pylori.