• Title/Summary/Keyword: 습관성 약물사용

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알카로이드독을 이용한 약물

  • 박종희
    • Journal of Life Science
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    • v.3 no.1
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    • pp.18-24
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    • 1993
  • 毒에는 비소, 수은처럼 無機毒과 식물, 동물성의 有機毒이 있으며, 有機毒에는 알카로이드, 배당체, 단백毒 등이 있다. 식물의 알카로이드毒을 중심으로 이것이 어떻게 藥物로서 이용되어 왔는지에 관해 다루었다. Morphine의 발견을 계기로 여러 종류의 식물 알카로이드가 계속 분리되었으며, 藥의 탐구의 새로운 길을 열었다. Morphine은 우수한 진통의 효과를 가졌지만, 흡수억제 및 습관성의 결점을 가지고 있다. 또, Areca catechu L. 의 종자(빈낭자)에는arecoline, arecaidine 등의 piperidine系의 알카로이드를 함유하고 있다. Arecoline은 副交感神經 흥분작용이 있고, 침분비 촉진, 比瀉 등으로 사용되어 왔지만, 지금은 그 용도가 적어졌다. 그리고 화살독이 되는 毒을 약물로 사용한 것은 Acontium屬 식물이 유일한 것이다. 중국에서는 이를 身體四肢關節의 마비, 疼痛의 회복, 대사기능실조의 회복 등의 목적으로 사용해 왔다.

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Factors related to the Experience of Violence Damage among Multi-cultural and General Adolescents in Korea: Focusing on health risk behavior (한국 다문화 청소년과 일반 청소년의 폭력피해경험 관련요인 : 건강위험행위를 중심으로)

  • Paek, Kyung-Shin
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.2
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    • pp.193-204
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    • 2022
  • This study was to identify factors related to the experience of violence damage, focusing on health risk behavior of multi-cultural and general adolescents in Korea. Data from the 15th online survey of youth health behavior (2019) was used to analyze 35,574 adolescents. The data were analyzed using complex sample analysis by using SPSS/Win 22.0. The multi-cultural adolescents had significantly higher experience of smoking and habitual drug use and violence damage than those ordinary adolescents. In both multi-cultural and general adolescents, the more they did not live with their family, the more they had smoking experience and habitual drug use experience, the higher they experienced violence. The experience of violence victimization of general youth was significantly related to gender, school, economic status, and drinking experience. To prevent the violence victimization of adolescents, social support for adolescents who do not live with their families is required, and careful attention is needed to adolescents who have smoking and drug use experience. In addition, since multi-cultural youth are more vulnerable to health risk behaviors and violence damage than general youth, educational programs are needed to induce multi-cultural youth to practice correct health behaviors and prevent experiences of violence.

Clinical Diagnosis and Its Medical Managements from Patients with Gastrointestinal Diseases (위장관 질환자의 임상진단과 치료방법)

  • 김재웅
    • The Korean Journal of Food And Nutrition
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    • v.10 no.2
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    • pp.186-192
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    • 1997
  • Endoscopic diagnosis and medical management from K43 and C45 patients, whose sex, occupation, character and life patterns are quite different each other, were discussed. The K43 was patient with erosive gastritis, which may caused by maldietary habits and life stresses. Although the effective drugs such as H2-receptor antagonists with atacids, H+/K+-pump inhibitors, prokinetics, colloidal bismuth, and sucralfates, were administrated for long time, symptomatic relief of abdominal pain was not improved. The tests of clinical phathology and abdominal sonogram were normal, visceral hypersensitivity was appeared from barostat test of stomach. However C45 had taken headache during every day life, and endoscopically confirmed as a gastric·duodenal ulcer patiant, which may caused by chronic use of NSAIDs. The her ulceric symptoms were suppressed from active stage to healing stage by using combination therapy for H. pylori with traditional antipeptic ulcer drugs, where as amitriptyline was administrated to the K43 but not effective. Nonulcer dyspepsia and irritable bowel syndrome is pooly defined, and affect about 15% of the population annually in U. S. A. but don't seek medical care. Author would like to point out that statistics for visceral pains are absent in Korea.

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Health and risk taking behaviors of freshmen in college (대학교 신입생들의 건강위험행태)

  • Ko, Hong Ki;Han, Jae Joon;Lee, Yoon;Yoo, Young;Lee, Kee Hyoung;Choung, Ji Tae;Park, Sang Hee
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1042-1049
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    • 2006
  • Purpose : This study was conducted to survey the preliminary data on risk behaviors and to identify the factors that prevent risk-behaviors in late adolescence. Methods : Freshmen(n=1,297) beginning the first semester in Korea University, Seoul, Korea completed self-administered risk behavior questionnaires, comprising 5 domains : demographics, smoking, drinking, drug abuse and sexual behavior. Results : The rate of smoking experience was higher in people having friends who smoke and the predictors of transition to current smoking were male gender, urban residence, friends' smoking, and nicotine dependence. The rate of high risk drinking was higher among students who are male and who had experience of heavy episodic drinking. The study group showed a low prevalence of narcotic users, but two-thirds of students could get medicine easily without prescriptions. The prevalence of sexual experience was 6.5 percent, and the sexual education was not a predictor of contraceptive behavior. The prevalence of homosexuality was 1.6 percent, and the rate of mostly heterosexuality was higher in female students. Conclusion : The main targets of youth health education should be campaigns aimed at atcessation of reinforcing risk behaviors and the development of a surveillance system for the prevention of chronic disease. These results can be used to find risk factors of health-risk behaviors among late adolescents.

Dating Violence Among Adolescents: A Review of Empirical Studies

  • Jang, Si-Won;Coulter, Martha
    • The Journal of Korean Society for School & Community Health Education
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    • v.9 no.2
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    • pp.47-64
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    • 2008
  • 연구배경: 데이트 폭력은 청소년을 포함한 젊은 인구집단의 신체적, 정신적 건강을 위협하는 중요한 공중보건 문제이다. 친밀한 남녀관계에서 시작되는 데이트 폭력의 위협에 노출되는 시기가 바로 청소년들이 생애주기 상 가장 급격히 발달하면서 많은 변화를 겪는 시기라는 것이 더 민감한 관심을 끈다. 그러나 이 문제 또는 이 문제를 해결하기 위한 노력들의 정도와 심각성을 이해하기 위한 구조적인 노력은 그다지 많이 이루어지지 않았다. 연구목적: 본 연구의 목적은 미국 청소년과 성인 초기 연령집단의 데이트 폭력 예방, 측정 도구, 위험 요인, 이환정도에 대해 지금까지의 관련 연구자료 고찰하여 일반적인 경향을 소개하는데 있다. 연구방법: 1990년부터 2007년까지 발표된 청소년과 성인 초기 인구의 데이트 폭력에 관한 60개의 논문을 검색하여 고찰하였다. 사회과학과 보건과학 관련 연구논문의 검색모듈을 활용하였는데 PsycInfo, Pubmed, 그리고 CINAHL였다. 연구결과: 데이트 폭력의 위험요인은 크게 개인적 요인, 심인적 요인, 가족 요인, 학교 및 친구 집단 요인으로 나뉘어진다. 개인적 요인으로는 자아존중감, 성, 인종, 약물사용, 성상대자 수, 과거 폭력경험이 유의미한 것으로 나타났다. 이 밖의 다른 개인적 요인, 즉 심인적 요인으로는 자기효능감, 식습관, 반사회적 행동 등이 있었다. 가족 요인으로는 가족 구조, 부모 성향이 유의미한 특성들이었으며 이 밖에 학교, 친구, 지역사회의 환경적 요인이 관련 있는 것으로 보고되었다.

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The Comorbidity of Attention Deficit Hyperactivity Disorder and the Effect of Methylphenidate on it (주의력 결핍 과잉 운동 장애 환자들의 약물치료 효과 및 Comorbidity에 관한 연구)

  • Lee, Jong-Bum;Park, Hyung-Bae
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.166-178
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    • 1993
  • The objectives of this study were to evaluate the effect of methylphenidate on attention deficit hyperactivity disorder (ADHD) and the comorbidity of the disorder, using child attention problem checklist to 56 (male: 38, female: 18) patients from, March 992 to February 1993. The results were as follows: Among 56 subjects, ADHD alone were 20 (335.71%) subjects, and with one additional diagnosis were 31 (55.35%) subjects and with two additional diagnosis were 5 (8.93%) subjects. There was significant improvement on symptoms in the scores rated by teachers in 7th and 28th day after menthlphenidate administration compared to baseline score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05). There was significant improvement on symptoms in the scores rated by parents in 28th day after methylphenidate administration improvement compared with 7th day score. In single administration of methylphenidate in Sunday morning score compared to afternoon score (P<0.05). In the administration of significant improvement on symptoms compared with the Sunday morning rating score of parents (P<0.05) and the 28th day comparison was also showed significant improvement on symptoms in the scores rated by teachers compared with the scores rated by parents on symptoms (P<0.05). Among group comparison, all groups showed significant improvements (P<0.05) except conduct disorder & oppositional defiant group.

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The Developing Trend of Cardiovacular Drug Coated Balloon Catheter (심장혈관용 약물코팅풍선카테터의 개발 동향)

  • Park, Junghun;Jo, Won-Il;Byeon, Dae-Heung;Kang, So Young;Nam, Choong-hyun;Seo, Kyoung-Woo;Park, Jun-Kyu
    • Applied Chemistry for Engineering
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    • v.33 no.5
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    • pp.545-550
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    • 2022
  • As a result of the rapid entry into an aging society and westernized eating habits, the number of heart disease patients caused by angina pectoris, myocardial infarction, and high blood pressure has increased by more than 100,000 over five years. Heart disease has consistently ranked second in the cause of death in Korea over the past eight years, and medical expenses consumed annually reach 6 trillion won. While various treatments are being proposed for more patients, drug-coated balloon catheters have been developed and gradually commercialized to solve the disadvantages of stent implantation such as restenosis and increased risk of bleeding due to long-term double antiplatelet medication. In Korea, it began to use a drug-coated balloon catheter with the first release of it called "SeQuent Please (Bibrown Korea)" in 2010. Its demand increased gradually as insurance benefits were applied in 2012. Drug-coated balloon angioplasty is increasing in use not only in Korea but also around the world, especially in the Asia-Pacific region, including Japan. Until now, the demand for domestic products is increasing, and if the efficiency in vivo and clinical trials is proven in the future, it is expected to be an effective procedure compared to high-risk stent implantation.

Association of Liver Dysfunction with Self-Medication History in Korean Healthy Male Adults (건강한 한국 성인남성의 자가약물복용력에 따른 간기능 장애 발생여부 조사)

  • Bae, Jong-Myon;Park, Byung-Joo;Lee, Moo-Song;Kim, Dong-Hyun;Shin, Myung-Hee;Ahn, Yoon-Ok
    • Journal of Preventive Medicine and Public Health
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    • v.29 no.4 s.55
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    • pp.801-814
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    • 1996
  • Background: Korean people could abuse healthy foods as well as medications, which might cause serious side effects. The aim of this study was elucidating liver dysfunction due to the self-medications of hepatotonics, healthy foods and herb medications by nested case-control study. Methods: Study subjects were drawn from male members of Seoul Cohort Study who were recruited by self-administered structured questionnaire survey through mailing to the healthy men between the age of 40 and 59 years through the program of biennial health check-up offered by Korea Medical Insurance Corporation(KMIC). The liver dysfunction was defined as the level of serum AST and ALT above 40 IU/L and increased in more than one hunderd per-cent during the 2 year follow-up period. To estimate the odds ratio between self-medication and liver dysfunction after controlling for potential confounders, logistic regression was performed. Results: During the follow-up period, 30 members were identified to fit into case criteria and 2,625 members were selected as control. In logistic regression analyses, history of healthy foods intake, age under 45 years, obesity, and habit of regular exercise were significantly associated with liver dysfunction. The following factors exhibited no statistical significance: intake of hepatotonics, of herb medicine; history of disease in family, of operation, and of radiologic examination; smoking habits and drinking amounts. Conclusion: The significant association between the intake of healthy foods and the liver dysfunction illustrates that chronically optional overuse of healthy foods might bring to hazards to health. As the increasing trend of the size of purchasing healthy foods in Korea, pharmacoepidemiologic studies evaluating the safety and efficacy of the widely used healthy foods should be performed in the near future.

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Effect of Loess Bedding with Loess Nanoparticles on Sleep Disorder (황토나노입자를 부착한 황토이불 사용이 수면장애에 미치는 효과)

  • Lee, Ku Yeon;Hahm, Suk Chan
    • Journal of Naturopathy
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    • v.11 no.1
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    • pp.9-17
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    • 2022
  • Background: No studies have reported on the effects of loess beddings on insomnia patients. Purpose: It studied the change in quality of life and quality of sleep after having 15 insomnia subjects use the bedding that emits far-infrared rays. Methods: After using loess bedding for the test group and general yellow bedding for the control group, the study was conducted in the form of a questionnaire on the WHO quality of life of the subjects. Results: In the overall quality of life evaluation, the pre-and post-changes significantly improved in the test group. Using loess bedding was greatly enhanced the physical change, the actual sleep time, and the quality of sleep of the test group. The period of sleep was significantly longer post-treating, and the habitual sleep efficiency was considerably higher, and sleep disturbance was significantly lower than before in the test group. Sleep drug use and daytime dysfunction after treating in the test group significantly improved the sleep effect. Changes in the Sociality Scale, Environmental Change Scale, and Quality of Life Scale significantly improved in the test group. The quality of life for 14 items in the test group was significantly correlated. Daytime drowsiness, depression, and anxiety scale changes were significantly improved in the test group. According to the predictive survey, the subjects felt warmth in their body and comfort in mind during and after using loess bedding and evaluated that sleep quality was good. Conclusions: The overall quality of life in the test group increased using loess bedding.