• Polymer(Korea)
• /
• v.29 no.5
• /
• pp.501-507
• /
• 2005

Small intestinal submucosa (SIS) had been widely used as a biomaterial without immune rejection responses. SIS sponges prepared by crosslinking with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC). SIS powders dissolved in $3\%(v/v)$ acetic acid aqueous solution for 48hrs and freeze-dried. EDC solution ($H_2O$ : ethanol = 5 : 95) as a crosslink agent was used in concentration of 100mM. In vitro, rat-BMSCs seeded in SIS sponges and induced the osteogenesis for 28 days. We have characterized the osteogenic potential of rat-BMSCs in SIS sponges by alkaline phosphatase activity(ALP), n assay, SEM and RT-PCR for osteogenic phenotype. In SEM, all morphology of SIS sponges was regular and showed interconnected pore structure. By RT-PCR analysis, we observed type I collagen expression. These results demonstrate osteogenic differentiation of rat-BMSCs. In conclusion, we confirmed that the morphology of surface, cross-section, and side of SIS sponges were highly porous with good interconnections between each pores, which can support the surface of cell growth, proliferation, and differentiation. This result indicates that SIS sponge is useful for osteogenesis of BMSCs.

• Korean Journal of Food Science and Technology
• /
• v.30 no.4
• /
• pp.902-907
• /
• 1998

In this study the anaerobic degradation of nitrate by in GFM (gel and foam matrix) and bead gel immobilized Paracoccus denitrificans DSM 65 in continous culture was conducted. A novel GFM immobilization system was developed in order to improve conventional system (bead). With increasing nitrate concentration in water, the nitrate reduction rate was increased. The observed maximum denitrification rate by in GFM immobilized cells was 177 mg/L h in buffered water, while that was 33 mg/L h in tap water. In comparison with bead system the reduction activity by GFM system showed $1.2{\sim}2.1$ times better. The denitrification activity was not changed after 16 days storage at $5^{\circ}C$ and also showed better activity than that of free cells or even bead immobilized cells.

• Horticultural Science & Technology
• /
• v.31 no.6
• /
• pp.732-739
• /
• 2013

'Akihime' plums picked at mature stage (50-70% red coloration of the fruit skin) were stored at $1^{\circ}C$ under air or controlled atmosphere (CA) storage regime as following 3% $O_2$ + 1, 3, 5, and 7% $CO_2$ for 50 days for the purpose of assessing the effect of CA storage on the maintenance of fruit quality and the reduction of chilling injury. Fruits stored under CA storage regime showed reduced respiration as well as ethylene production rates compared to the fruits stored in air. Quality attributes including weight loss, Hunter 'a' values, soluble solids content, titratable acidity, and firmness showed smallest changes in fruits stored under CA conditions except for 3% $O_2$ + 7% $CO_2$. High incidence of physiological disorders including chilling injury, flesh browning, and decay were found in fruits stored under both air and CA of 3% $O_2$ + 7% $CO_2$. In our study, the CA storage regime of 3% $O_2$ + 5% $CO_2$ was found the most effective for maintaining overall fruit qualities of 'Akihime' plums produced in Korea, also delayed the development of chilling injury including lack of juiciness and flesh browning. From the results, storage at 3% $O_2$ + 5% $CO_2$ was selected as an optimal condition of 'Akihime' plum for extending storage life up to 50 days at $1^{\circ}C$.

• Membrane Journal
• /
• v.15 no.3
• /
• pp.198-205
• /
• 2005

Double-layered polymer films to assay the radioactive contamination were formulated using polysulfone (PSF) and cerium activated yttrium silicate (CAYS), consisting of a dense support layer and a CAYS-holding top layer prepared via the diffusion-induced phase inversion. As the vapor exposure process was omitted, the CAYS-holding layer showed a typical asymmetric structure, with CAYS being transfixed into the polymer network spread with large macropores. With the increase in vapor exposure time before immersion, morphology of the films transformed from asymmetric to sponge-like structures, with CAYS being localized in cellular structure. The border structure between the two layers reflects the phase inversion behavior of a cast solution during the coagulation. In the radioactive detection, the polymer phase in a film holding a sponge-like structure is so dense that the radionuclides, deposited on the film, could not filter through the phase, consequently resulting in the loss in the detection efficiency of the film.

• Korean journal of food and cookery science
• /
• v.23 no.5
• /
• pp.696-702
• /
• 2007

The effect of different steamed garlic powder concentrations on sponge cake quality were investigated by analyzing both physicochemical and sensory properties. The sponge cakes were mixed with either steamed and freeze-dried garlic powders at different ratio [0, 2, 4, 6, 8 and 10 % (w/flow w)]. The density of the prepared dough increased with increasing amounts of steamed garlic powder when the concentrations were over 4%. The heights of the sponge cakes ranged from $3.53{\pm}0.12{\sim}3.60{\pm}0.15cm$ in the $4{\sim}8%$ steamed garlic powder samples, and were significantly higher than the control. The specific loaf volume of the cake was $3.86{\pm}0.07mL/g$ the highest in the 4% steamed garlic powder samples. When the garlic powder concentration was over the 6%, the specific loaf volumes of the sponge cakes decreased with increases in garlic powder contents. The measured L- and b-values of the crust were significantly decreased with increasing garlic powder concentration while the a-value gradually increased. The L-value of the crumb increased with increasing steamed garlic powder concentration, especially at concentrations greater than 4%. The a-values were higher in the steamed garlic powder treatments than in the control. however, no significant differences were found in the concentrations over 4%. The hardness of the control was $812.42{\pm}56.69g/cm^2$, whereas it ranged from $1005.36{\pm}43.65{\sim}1522.78{\pm}204.95g/cm^2$ in the experimental groups. Hardness increased with increasing garlic powder concentration. When considering moistness, overall acceptability, and other characteristics, the optimal concentration of steamed garlic powder was found to be 4%.

• The tire
• /
• s.45
• /
• pp.20-24
• /
• 1973

자동차타이어의 최대의 유리성은 공기를 잘 활용하는 데 있다. 그러나 일단 공기를 잃은 타이어는 즉시 사용불능으로 화하고수리는 할 수 있어도 시간과 수리라 하는 큰 로쓰를 초래하는 결과가 된다. 그래서 과거 80년간 많은 타이어 기술자는 빵꾸라고 하는 현상으로부터 탈출할 수 있는 타이어의 개발에 어느 정도의 노력과 지혜를 짯었는가? 동경의 타이어…라고 하면 "노우 빵꾸 타이어"라고까지 일컬어진다. 그것은 시대가 고속화에로 진입함에 따라 빵구는 귀중한 생명까지도 빼았는 큰 사고를 초래하는 원인의 하나로도 되어 왔든만큼 더욱 중대성을 가져왔다. 이때문에 절대로 빵구나서는 곤란하다고 하는 용도의 차량에 장착된 타이어에 대해서는 승차감, 속도 등의 요구는 무시하고서 이미 여러 가지의 노우 빵꾸 타이어가 제조되고 있다. 그렇다고 해서 보급의 속도와 보통의 승차감의 노우 빵꾸 타이어는 생각할 수 없는 것일까?…이러한 발상으로부터 개발된 타이어에 "파아마포옴 타이어"라고 하는 것이 있다. 매이커어는 미국의 굳이어 이다. 그럼 그 마아마포옴 타이어란? ……간단히 말하면 중의 공기를 스폰지상의 포옴재로 한 것이다. 따라서 승차감은 결코 나쁘지 않다. 속도도 50km까지라면 염려없다. 하나 그 타이어의 제조법이 간단하지가 않다. 특히 "열처리의 단계에서 포옴재를 타이어의 속에 균등하게"라고 하니 큰 일이다. 이하는 일본 굳이어 타이어 기술부에 의한 파아마 포옴 타이어의 개설.

• KSBB Journal
• /
• v.26 no.3
• /
• pp.217-222
• /
• 2011

Itraconazole is a triazole antifungal agent to inhibit most fungal pathogens. To improve the oral absorption and dissolution of poorly water-soluble itraconazole, microsponge system composed of $Eudragit^{(R)}$ E100 and polyvinyl alcohol(PVA) formulated by quasi-emulsion solvent diffusion method, and its physicochemical properties and pharmacokinetic parameters of itraconazole were studied. The microsponge of itraconazole were discrete free flowing micro sized particles with perforated orange peel like morphology as visualized by scanning electron microscope (SEM). Results showed that the drug loading efficiency, production yield, and particle size of itraconazole microsponge were affected by drug to polymer ratio, the volume of internal phase containing methylene chloride, stirring rate and the concentration of PVA used. Also, the results showed that the dissolution rate of itraconazole from the microsponges was affected by drug to polymer ratio. In other words, the release rate of itraconazole from microsponges was increased from at least 27.43% to 64.72% after 2 h. The kinetics of dissolution mechanism showed that the dissolution data followed Korsmeyer-Peppas model. Therefore, these results suggest that microsponge system can be useful for the oral delivery of itraconazole by manipulating the release profile.

• Journal of Nutrition and Health
• /
• v.36 no.4
• /
• pp.344-351
• /
• 2003

The purpose of this study was to elucidate effects of fructooligosaccharide on gastrointestinal tract and blood lipids of rats when this was supplied as purchased condition or oligosaccharide containing sponge cake. Male Sprague-Dawley rats were assigned to one of 3 treatments 1) control diet 2) 7.5% fructooligosaccharide containing diet (FOS diet) 3) lyophilized sponge cake powder containing diet (FOS-C diet). The sponge cake was made with fractooligosaccharide which replaced 40% of its surose, and the final concentration of fructooligosaccharide in FOS-C diet was 7.5%. Cecal and fecal water contents, amount of cecal content, and cecal wall weight were higher from fructooligosaccharide consumption, whereas total gut transit time was longer in rats consuming fructooligosaccharide compared with those fed control diet. Cecal and fecal pH were lower in FOS and FOS-C groups than in control group. Total cecal SCFA pools were higher from ingesting fructooligosaccharide containing diets compared with control diet. Serum triglyceride levels were lower in rats fed FOS and FOS-C diet than those fed control diet, while serum cholesterol levels were unaffected by treatment. Therefore the effects of fructooligosaccharide in sponge cake on serum lipids and gastrointestinal tract were similar to those of intact fructooligosaccharide. Also, adding 7.5% of FOS accompanied diarrhea symptom which suggests some precaution are needed when using FOS.

• Journal of Powder Materials
• /
• v.17 no.5
• /
• pp.385-389
• /
• 2010

Titanium powders have been usually produced by de-hydrogenating treatment in vacuum with titanium hydride ($TiH_2$) powders prepared by milling of hydrogenated sponge titanium, $TiH_x$. The higher stoichiometry of x in $TiH_x$, whose maximum value is 2, is achieved, crushing behavior is easier. $TiH_x$ powder can be, therefore, easy to manufactured leading to obtain higher recovery factor of it. In addition, contamination of the powder can also minimized by the decrease of milling time. In this study, the hydrogenation behavior of sponge titanium was studied to find the maximum stoichiometry. The maximum stoichiometry in hydride formation of sponge titanium could be obtained at $750^{\circ}C$ for 2 hrs leading to the formation of $TiH_{{\sim}1.99}$ and the treating temperatures lower or higher than $750^{\circ}C$ caused the poor stoichiometries by the low hydrogen diffusivity and un-stability of $TiH_x$, respectively. Such experimental behavior was compared with thermodynamically calculated one. The hydrogenated $TiH_{1.99}$ sponge was fully ball-milled under -325 Mesh and the purity of pure titanium powders obtained by de-hydrogenation was about 99.6%.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.11
• /
• pp.635-644
• /
• 2018

This descriptive study examined the practical nursing guidelines for the prevention of pressure injuries (PI) in operating rooms and their application. Method: Four general hospitals and three specialized hospitals located in Seoul, Incheon, and Gyeonggido province were selected through an online randomization program and nurses at these hospitals who participated in operations and had at least six months work experience were surveyed. Data were collected from January to April 2018 through a survey distributed to 150 nurses, 129 of whom returned the survey (86% recovery rate). The results showed that 43 nurses provided PI prevention care for patients in a lateral position (33.3%), 37 for patients in a supine position (28.7%), and 36 for patients in a prone position (27.9%). Gel was most widely used as the supporting surface material (102 nurses; 79.1%), followed by sponge (62 nurses; 48.1%), and cotton (47 nurses; 36.4%). Skin was often inspected twice, before and after the use of a supporting surface (90nurses; 69.8%), but no designated tool was used to determine the risk of PI developing (76 nurses; 58.9%). Additionally, the patient's position during surgery (83 nurses; 64.3%) and the length of the operation (i.e., more than two hours, in this case) (49 nurses; 38.0%) were determining factors for whether to use a supporting surface. The operating room nurses used the gel, sponge, and cotton as the supporting surfaces for the prevention of PI and confirmed that the cutoff operation time for the use of a supporting surface was more than 2 hours.