• The Korean Journal of Pharmacology
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• v.29 no.1
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• pp.65-72
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• 1993

Ultraviolet light radiation (UVR) did not affect resting tension of isolated thoracic aortae of rats. In aortic rings contracted with phenylephrine, however, UVR produced contractile and relaxant responses in preparations with and without endothelium, respectively. The contractile response was dependent upon the duration $(10{\sim}320\;sec)$ of irradiation, while the relaxation was not. UVR-induced contractions in endothelium-intact rings were significantly potentiated by increasing the concentrations of phenylephrine from $10^{-7}M$ to $10^{-5}M$, and also by addition of $10^{-6}M$ acetylcholine, $10^{-7}M$ isoproterenol and $3.5{\times}10^{-8}M$ nitroglycerine. However, addition of $10^{-6}M$ phentolamine, or $10^{-7}M$ to $10^{-6}M$ LY83583 inhibited the contraction or reversed the contraction to a relaxation. In endothelium-removed preparations the UVR-induced relaxation was attenuated by increasing concentractions of phenylephrine, and by addition of isoproterenol, nitroglycerin, phentolamine or LY83583. These results suggest that UVR produces contractile and relaxant responses in rat thoracic aortae with and without endothelium, respectively, and that the contractile effect results from the inhibition of endothelium-derived relaxing factor (EDRF) release by UVR the inhibition of and/or is in part re-lated to some endothelium-derived contractile factors (EDCFs).

• Journal of the Korea Concrete Institute
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• v.20 no.2
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• pp.131-138
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• 2008

Humidity and strain were estimated for understanding the relation between humidity change by self-desiccation and shrinkage in high-performance concrete with low water binder ratio. Internal humidity change and shrinkage strain were about 10%, 4% and $320\times10^{-6}$, $120\times10^{-6}$ respectively on concrete with water binder ratio 0.3, 0.4 and from the results, humidity change and shrinkage represented the strong linear relation regardless of mixture. For specifying the relation on internal humidity change and autogenous shrinkage strain, shrinkage model was established which is driven by capillary pressure in pore water and surface energy in hydrates on the assumption of a single network and extended meniscus in pore system of concrete. This model and experimental results had a similar tendency so it would be concluded that the internal humidity change by self-desiccation in HPC originated in small pores less than 20 nm, therefore controlling plan on autogenous shrinkage might be focused on surface tension of water and degree of saturation in small pore.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.11a
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• pp.681-684
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• 2008

In case of recycled fine aggregate, density and absorption ratio is lower than natural one, so it is used to lower value added products and it is limited its usage. It is reported that Compressive and tensile strength of recycled concrete is more deteriorate and shrinkage properties is very deteriorate because high absorption of recycled fine aggregate. Accordingly, in this study, it is develop that dry manufacturing system composed specific gravity separator of high-speed rotation impact type, reclaimer of minuteness fine aggregate and evaluate that shrinkage properties of recycled concrete using recycled fine aggregate at producing this system. Hereafter, it is present that fundamental data to practical use recycled fine aggregate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.628-634
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• 2016

Many pitchers suffer from various types of injury (distortion, sprain and so on). The rate of injury is increased if there are differences in strength between the extensor and flexor muscles when a joint movement is performed with maximum speed. However, there has been insufficient research into the injury caused by strength differences between the extensor and flexor muscles. Thus, the purpose of the study was to examine the effects of elbow ulnar collateral ligament injury on the maximal isometric strength in young baseball pitchers. The data collection was conducted for 2 weeks. The subjects (n=36) who participated in this study were placed into either the injury group (n = 18, IG) or normal group (n = 18, NG). The maximal isometric strength for the pectoralis major (PM), infraspintus (I), biceps brachii (BB), triceps brachii (TB), flexor carpi radialis (ECR) and extensor carpi radialis (FCR) muscles were determined by an isometric strength machine (K-DFX) and then the differences in strength were calculated by muscle group. All of the data were analyzed by SPSS 18.0 with the independent t-test. In the results, the maximal isometric strengths in the IG for the I (p=0.035), BB (p=0.031) and TB (p=0.041) were significantly lower than those in the NG, while that for the ECR (p=0.047) was significantly greater. In addition, the differences of the maximal isometric strength between the PM and I (p = 0.008), BB and TB (p = 0.002), and FCR and ECR (p = 0.032) in the IG were significantly greater than those in the NG. In conclusion, the differences in muscle strengths of the subjects in the IG were greater than those in the NG, which suggests that they might have a higher injury rate in the future. However, they might be able to recover from their injury and achieve better performance if the differences in strength were reduced by training.

• Physical Therapy Korea
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• v.10 no.4
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• pp.61-68
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• 2003

본 연구의 목적은 운동강도(최대근수축의 10, 30, 50, 70%)에 따라 유발되는 국소적인 근피로가 슬관절의 위치감각 인지에 미치는 영향을 연구함으로써 근력강화의 운동치료적 효과와 운동학습과 관련된 효과를 동시에 만족시키는 최적의 운동강도를 제시하는 것이었다. 대상자는 건강한 성인여자 40명이었다. 청각을 통한 위치감각 정보를 제공하는 장치와 원판 각도계가 부착된 등속성 Cybex를 사용하였다. 근피로의 상태를 확인하기 위해서 근전도를 이용하여 주파수 스펙트럼 분석을 실시하였다. 청각되먹임이 주어진 각도와 대상자에 의해 재생되어진 각도의 오차값들과 근피로의 변화를 비교하기 위해 일요인 분산분석을 이용하였다. 오차값들의 평균은 50%의 군에서 가장 작았으며 근피로 또한 70%의 군에서만 크게 생성되었다. 따라서 최대 근 수축력의 50%가 운동치료 시 가장 효과적인 운동강도임을 알 수 있었다.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.2 no.2
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• pp.25-37
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• 2004

To provide reflection diagnostical basic-data by ultrasonography intended for 38 male/female students used by ultrasound imaging system and dynamometer, compared the MVIC and muscle thickness take an accurate measurement of elbow flexor and knee extensor of thickness and MVIC, in confirmity with distinction of sex and then analysised of correlation in muscle thickness-MVIC, MVIC-weight, weight-muscle thickness, it shows statiscally significant difference MVIC and muscle thickness according to sex. Also there is a high interrelation between two. As well as it shows that there is a different between sex in the MVIC of same thickness and MVIC of same weight. This difference will be related with preportions of muscle fiber type in view of the results by preceded research, it needs to be prerequisite analysis of difference in sex with a great variety of ways hereafter.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.37-37
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• 1992

세포의 흥분성과 막전위의 조절에 있어서 $K^{+}$ channel의 역할이 크다는 사실이 인정 됨으로서 (Rudy, 1988) $K^{+}$ channel 개방 약물의 약리학적 연구와 임상적 응용에 대한 관심은 높아졌다. Cromakalim, nicorandil 및 pinacidil등이 혈관 평활근을 특히 예민하게 이완시킨다. 작용기전으로서는 세포의 원형질 막을 통한 $K^{+}$ 전도의 항진과 $K^{+}$ outward current의 증가가 막 과분극을 일으킨다. 이러한 결과는 막흥분에 의한 voltage-dependent $Ca^{++}$ channel을 닫게하고 세포내 free $Ca^{++}$의 농도를 감소시켜 혈관의 흥분성과 수축력의 감소를 야기하여 근이완을 야기한다. 한편, 평활근 세포막의 $Na^{+}$-$K^{+}$ ATPase도 활성화하면 electrogenic pump를 가동하여 막 과분극을 일으키고 막 흥분성을 저하시킨다. $Na^{+}$-$K^{+}$ pump는 세포 바깥의 $K^{+}$과 세포안의 $Na^{+}$농도에 의하여 활성화한다.

• Journal of the Korean Geotechnical Society
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• v.16 no.6
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• pp.15-21
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• 2000

본 논문은 체적이 변하는 흙에 대하여 새로운 흙-수분 특성곡선 이론을 제시하고 이를 실험적으로 규명하였다. 그 결과, 점토와 같이 불포화되는 과정중 체적변형이 발생하는 흙의 흙-수분 특성곡선은 간극비와 흡인력의 함수이므로 체적변화를 무시할 수 없음이 밝혀졌다. 따라서 본 논문에서는 체적변화가 있는 경우 흙-수분특성곡선을 구하기 위하여 두가지 실험법을 채택하였다. 그 첫째는 전통적인 압력판 추출시험과, 중량함수비와 간극비와의 관계를 알 수 있는 수축한계시험을 실시하여 조합하는 방법이며, 둘째 방법은 압력판 셀을 새로인 고안하여 추출시험시에 체적 수축도 측정할 수 있는 수정된 압력판 셀 시험방법을 이용하는 것이다. 이 시험결과를 3차원 상의 면(surface)에서 표현하여, 체적변형을 고려한 흙-수분 특성을 규명할수 있도록 하였다.

• Journal of Sensor Science and Technology
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• v.30 no.3
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• pp.185-189
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• 2021

Herein, we propose a functional polymer cantilever to enhance maturation and contractile force of cardiomyocytes. The proposed cantilever consists of a surface-patterned polymer substrate and silver nanowires (AgNWs). The AgNWs are transferred to the PDMS substrate using conventional molding techniques. This thin metallic surface significantly improves the adhesion of cardiomyocyte on the surface-patterned PDMS with the hydrophobic characteristics. In addition, the use of AgNWs improves the visibility of the conducting PDMS substrate for the observation of cardiomyocyte through an inverted microscope. The AgNWs also assist in synchronizing each cardiomyocyte to maximize its contractile force.

• Journal of Yeungnam Medical Science
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• v.11 no.2
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• pp.314-322
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• 1994

This study aimed to investigate the existence of GABA receptor and the mechanisms of action of GABA and diazepam on the trachealis muscle isolated from dog. Horizontal muscle strips of $2mm{\times}15mm$ were prepared from canine trachea, and isometric myography in isolated muscle chamber bubbled with 95/5%-$O_2/CO_2$at $36^{\circ}C$, at the pH of 7.4 was performed. Muscle strips contracted responding to the electrical field stimulation (ESP) by 2~20 Hz, 20 msec, monophasic square wave of 60 VDC GABA and diazepam suppressed the EFS-induced contractions to the similar extent, significantly. (p<0.05) Bicuculline, a $GABA_A$ receptor antagonist blocked both GABA- and diazepam- inhibitions; but DAVA, a $GABA_B$ receptor antagonist did not affect either of them. These results suggest that in the canine trachealis muscle, there may be only $GABA_A$ receptor, and GABA and diazepam inhibit the contractility via $GABA_A$A receptor.