• Title/Summary/Keyword: 수축결합

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The convergence effect of phenylephrine, isoprenaline and prazosin on vascular contractility (혈관 수축성에 대한 phenylephrine, isoprenaline 및 prazosin의 융합성 조절 효과)

  • Je, Hyun Dong;Min, Young Sil
    • Journal of Convergence for Information Technology
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    • v.12 no.4
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    • pp.119-125
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    • 2022
  • In the study, we endeavored to investigate the effect of phenylephrine, isoprenaline and prazosin on the tissue-specific vascular contractility and to determine the mechanism involved. There were few reports addressing the question whether thin or thick filament modulation is included in phenylephrine, isoprenaline and prazosin-induced regulation. We hypothesized that isoprenaline and prazosin play a role in tissue-dependent regulation of vascular contractility. Denuded arterial muscles of Sprague-Dawley male rats were suspended in organ baths and isometric tensions were transduced and recorded using isometric transducers and an automatic data acquisition system. Interestingly, sustained continuous contraction of thoracic and abdominal aorta. Furthermore, isoprenaline and prazosin together with phenylephrine inhibited transiently and persistently vasoconstriction of thoracic and abdominal aorta suggesting that additional mechanisms (e.g. decreased receptor density, chemical interaction, postreceptor signaling or distribution of agonists) might be included in the modulation of vascular contractility.

Effects of Ion Specificity on the Expansion Behavior of Polymer Gel with Phenyl Ring (Phenyl 고리를 갖는 고분자 겔의 팽윤거동에 대한 이온 특성화 효과)

  • Ahn, Beom-Shu
    • Journal of the Korean Applied Science and Technology
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    • v.29 no.2
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    • pp.278-285
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    • 2012
  • Effects of ion species on the expansion behavior of Poly(styrene sufonic acid)(PSSA) hydrogel were investigated in aqueous solution of selected anions, cations and hydrophobic ions. The deexpansion extent of Poly(stylene sulfonic acid) gel follow the sequence $SCN^-$<$Br^-$<$Cl^-$<$F^-$ in low concentration solutions due to the destabilization of anions to hydrogen bond between ${SO_3}^-$ and water. The deexpansion in cations followed the sequence of counterion interactions between ${SO_3}^-$ and cations. It was discussed the effects of ions on the hydrogen bonding through ${SO_3}^-$ and phenyl ring in salt solutions. Other interactions, such as the cation-${\pi}$ interaction, hydrophobic interaction, and dispersion force, contributed to the ion specific swelling of PSSA hydrogel.

Prediction of Autogenous Shrinkage on Concrete by Unsaturated Pore Compensation Hydration Model (불포화 공극 보정 수화도 모델을 이용한 콘크리트의 자기수축 예측)

  • Lee, Chang Soo;Park, Jong Hyok
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.5A
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    • pp.909-915
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    • 2006
  • To predict autogenous shrinkage of concrete, unsaturated pore compensation factor could be calculated by experiments of autogenous shrinkage of cement paste on the assumption that the differences between degree of hydration and strain rate of autogenous shrinkage are unsaturated pore formation rate. Applying unsaturated pore compensation factor on modified Pickket model considering contribution factor and non-contribution factor to autogenous shrinkage of concrete, experimental data and existing model were compared. From the results modified Pickket model was verified to present similar tendency between Tazawa model and experimental data, but CEB-FIP model might be corrected because this model uses ultimate autogenous shrinkage underestimated and the same autogenous time function of concrete material properties considering only compressive strength.

An Experimental Study on Durability of Mortar and Concrete using Shrinkage reducing typed Superplasticizer (수축저감형 혼화제를 이용한 모르타르 및 콘크리트의 물리적 특성에 관한 기초적 연구)

  • Woo, Hyung-Min;Park, Hee-Gon;Lee, Young-Do
    • Journal of the Korea Institute of Building Construction
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    • v.16 no.6
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    • pp.561-569
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    • 2016
  • Concrete is cheap, easy to deal with, and the quality is satisfactory. Also, it is one of the easiest materials to get because chemical composition of cement is similar to chemical composition of surface. On the other hand, it is so vulnerable to transform because of weak binding capacity and low binding energy that it produces cracks. Cracks decline durability, usability, safety of structures and damage exterior. In order to decline drying shrinkage crack, this study used shrinkage reducing typed Superplasticizer, which is combination of and water-reducing agent for convenience, different with existing study using AE agent, water-reducing agent, shrinkage reducing agent,. Considering SRS field application possibility, this study planned to mix concrete and mortar generally used in ready-mixed concrete company and did basic experiment depending on a change of SRS content ratio and admixture. Based on the experiment result. It is judged that SRS admixture 2% is proper ratio when Given the intensity and length change. Also mass combination will conduct follow-up studies.

Effect of $Na^+$ Removal on the Action of Ethanol in Cat Ileal Longitudinal Muscle (장관 평활근에서 Na-free용액이 Ethanol의 효과에 미치는 영향)

  • Suh, Duk-Jun;Kim, So-Sun;Woo, Jae-Suk;Kim, Young-Keun
    • The Korean Journal of Physiology
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    • v.20 no.1
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    • pp.125-133
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    • 1986
  • The effect of ethanol on the contraction of intestinal smooth muscle in Na-free solution was studied using cat ileal longitudinal muscle strips. Ethanol $(0.5{\pm}4%)$ inhibited both the spontaneous mechanical activity and base-line tension in normal physiological salt solution. However, in Na-free solution it induced a reversible contraction. The excitatory effect by ethanol in Na-free solution was increased with increasing the concentrations of ethanol and the time incubated in Na-free solution. The excitatory response by ethanol was reduced by increasing the concentrations of Na in incubated medium . Ethanol-induced contractile response was not affected by $Ca^{2+}$ removal in bathing medium. In Na-free solution, the contraction by ethanol was inhibited by Las. but was not affected by verapamil. The contraction induced by Na removal in solution was inhibited by the pretreatment of ethanol. These results suggest that ethanol may induce the contraction by increasing the release of superficially membrane-bound $Ca^{2+}$ and/or intracellular $Ca^{2+}$ in Na-free physiological salt solution.

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A STUDY OF POLYMERIZATION SHRINKAGE OF COMPOSITE RESIN ACCORDING TO FILLING METHODS USING STRAIN GAUGE (스트레인 게이지를 이용한 적층방법에 따른 복합레진의 중합수축에 관한 연구)

  • Kim, Eung-Hag;Kim, Jong-Soo;Yoo, Seung-Hoon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.35 no.1
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    • pp.18-29
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    • 2008
  • The purpose of this study was to compare the polymerization shrinkage of several filling methods using strain gauges. In this study, a light-emitting diode(LED) curing unit(Elipar Freeligh2, 3M EPSE, USA) and plasma arc lamp(PAL) curing unit(Flipo, LOKKI, France) were used for curing, Filtek $Z350^{TM}$(3M EPSE, USA) composite resin was used for the cavity filling. Sixty permanent bicuspid teeth, that were extracted for orthodontic treatment, were studied. The cavities were prepared on the occlusal surface and were filled using the following methods : 1) bulk filling, 2) parallel filling, 3) oblique filling The strain was recorded on the buccal, lingual, mesial and distal surfaces and the strain values were computed into stress values. The shear bond strength of each filling method was tested using a Micro Universal Testing machine. The results can be summarized as follows: 1. In the strain changes, all LED and PAL curing groups showed an increase on the buccal surface and a slow decrease as time elapsed. 2. In the strain changes of the mesial and distal surfaces, the decreases and increases were shown repeatedly and reduced as time elapsed. 3. There were no significant statistical strain changes among filling methods in the LED or PAL curing groups. 4. There were significant statistical strain changes between the LED and PAL curing groups on the buccal surface(p<0.05). 5. From the shear bond strength results, in the LED curing group, filling method 3 showed lower surface stress than filling method 1 and 2(p<0.05). In the PAL curing group, there were no significant statistical strain changes between each filling method. 6. The surface stress of each group was lower than the shear bond strength.

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Multi-physics Modelling of Moisture Related Shrinkage in Concrete (콘크리트 수분관련 수축에 관한 다중물리모델)

  • Lee, Chang-Soo;Park, Jong-Hyok
    • Journal of the Korean Society of Hazard Mitigation
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    • v.9 no.2
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    • pp.1-9
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    • 2009
  • Water binder ratio combine high-performance concrete shrinkage of less than 0.4 to determine the transformation to a total shrinkage of water to move outside and internal consumption of moisture due to drying shrinkage and autogenous shrinkage, and then, the relative humidity changes and strain to be approached by surface physics describe the relationship between self-desiccation and autogenous shrinkage was set. To verify the self-desiccation in the humidity shrinkage and humidity measurements performed, and the research model, Tazawa, CEB-FIP model than to let the measure and the most similar results in this study based on self-desiccation model, autogenous shrinkage didn't represent the linear shrinkage by the drying shrinkage of the external moving but exponential relationships, unlike with the nature and rapid in the early age properly describes the attributes in shrinkage could see. After this research to move moisture and to reflect the shrinkage model, temperature, moisture transfer, strain analysis by multi-physics model is very similar to the results of mock-up specimen measurements performed for this research, the value measured by the internal consumption of moisture, therefore self-desiccation and a multi-physics model considering autogenous shrinkage might be relevant.

Evaluating Early Age Shrinkage Behavior of Ultra High Performance Cementitious Composites (UHPCC) with CSA Expansive Admixture and Shrinkage Reducing Agent (CSA계 팽창재 및 수축 저감제의 혼입에 따른 UHPCC의 초기 수축 거동 평가)

  • Yoo, Doo-Yeol;Park, Jung-Jun;Kim, Sung-Wook;Yoon, Young-Soo
    • Journal of the Korea Concrete Institute
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    • v.23 no.4
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    • pp.441-448
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    • 2011
  • In this study, experimental tests of chemical and autogenous shrinkage were performed to evaluate the early age shrinkage behaviors of ultra high performance cementitious composites (UHPCC) with various replacement ratios of silica fume (SF), shrinkage reducing agent (SRA), expansive admixture (EA), and superplasticizer (SP). Starting time of self-desiccation, was analyzed by comparing the setting times and the deviated point of chemical and autogenous shrinkage strains. The test results indicated that both SF and SRA augment the early age chemical shrinkage, whereas SP delays the hydration reaction between cement particles and water, and reduces chemical shrinkage. About 49% of autogenous shrinkage was depleted by synergetic effect of SRA and EA. The hardening of UHPCC was catalyzed by containing EA. Self-desiccation of UHPCC occurred prior to the initial setting due to the high volume fraction of fibers and low water-binder ratio (W/B).

Shrinkage Reduction Performance of HPFRCC Using Expansive and Srhinkage Reducing Admixtures (팽창재와 수축저감제를 사용한 HPFRCC의 수축 저감 성능)

  • Park, Jung-Jun;Moon, Jae-Heum;Park, Jun-Hyoung;Lee, Jang-Hwa;Kim, Sung-Wook
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.5
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    • pp.34-40
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    • 2014
  • High-performance fiber-reinforced cement composite (HPFRCC) shows very high autogenous shrinkage, because it contains a low water-to-binder ratio (W/B) of 0.2 and high fineness admixture without coarse aggregate. Thus, it needs a method to decrease the cracking potential. Accordingly, in this study, to effectively reduce the shrinkage of HPFRCC, a total of five different ratios of SRA (1% and 2%), EA (5% and 7.5%), and a combination of SRA and EA (1% and 7.5%) were considered. According to the test results of ring-test, a combination of SRA and EA (1% and 7.5%) showed best performance regarding restrained shrinkage behavior without significant deterioration of compressive and tensile strengths. This was also verified by performing modified drying shrinkage crack test.

Prediction Model for Autogenous Shrinkage of High Strength Fly Ash Concrete (고강도 플라이 애쉬 콘크리트의 자기수축 예측 모델)

  • Lee, Hoi-Keun;Lee, Kwang-Myong;Kim, Woo
    • Journal of the Korea Concrete Institute
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    • v.15 no.1
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    • pp.134-142
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    • 2003
  • Autogenous shrinkage, a significant contributor of early-age cracking of high strength concrete (HSC), must be avoided or minimized from an engineering point of view. Therefore, it is necessary to study how to reduce and to predict autogenous shrinkage with respect to tile control of early-age cracking. In this study, autogenous shrinkage of HSC with various water-binder ratio (W/B) ranging from 0.50 to 0.27 and fly ash content of 0, 10, 20, and 30% were investigated. Based on the test results, thereafter, a prediction model for autogenous shrinkage was proposed. Test results show that autogenous shrinkage increased and more rapidly developed with decreasing the W/B. Also, the higher fly ash contents, the smaller autogenous shrinkage. In particular, even if much autogenous shrinkage occurs at very early-ages, stress may not be developed while the stiffness of concrete is low. In order to consider the change of concrete stiffness, the transition time referred as stiffening threshold, was obtained by monitoring of ultrasonic pulse velocity evolution and considered in the autogenous shrinkage model. From a practical point of view, the proposed model can be effectively used to predict autogenous shrinkage and to estimate stress induced by autogenous shrinkage.