• Sleep Medicine and Psychophysiology
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• v.3 no.1
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• pp.15-24
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• 1996

After rapid eye movement(REM) sleep was idenified in 1953, a lively interest developed concerning a possible role of this kind of sleep in memory processes. The author reviewed studies relating REM to memory/learning. Many studies in animals and humans gave substantial evidence for relating REM sleep to memory function. The evidence supporting the position taken in this paper comes from experiments showing that : (1) learning session is followed by the significant augmentation of REM sleep : (2) REM sleep deprivation, prior to learning or immediately thereafter, impairs the formation of a permanent memory/learning : (3) there is a vulnerable period of time(eg, REM sleep "window") following succussful learning, during which REM sleep deprivation results in memory impairment : (4) theta rhythm which develops during REM sleep induces long-term potentiation in hippocampus : (5) there are some evidences providing the relationship of neurotransmitter systems to the maintenance of REM sleep and memory storage processes.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.44-44
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• 2015

저수지나 하천 사면에서 발생하는 산사태와 토석류는 저수지와 하천 수체에 충격을 가한다. 이로 인해 발생하는 수면 충격파는 전파되어 반대편 제방으로 파의 처오름 또는 댐 제체위로의 물넘이로 큰 피해를 줄 수 있다. 최근 외국에서는 2차원 충격파 생성 및 전파의 기본 과정을 구명하기 위한 실험적 연구가 이뤄지고 있으며, 이들 연구들은 충격파의 발생과 전파, 사면활동 물질과 수체의 상호작용 그리고 자유 수면과 유속분표의 발달에 대한 자세한 관측 자료를 제시하고 있다. 아울러 충격파에 영향을 주는 지배 매개변수를 제시하고 있다. 하지만, 이러한 실험적 연구의 최근 진보에도 불구하고, 이들 지배 매개변수를 고려한 충격파 지배공식들은 대상 지역의 복잡한 바닥 지형이나, 평면적 지형 변화를 단순한 추정치로만 고려하게 된다. 따라서 복잡한 지형조건에서 토석류와 수체의 상호작용과 수면 충격파의 전파를 합리적으로 해석하는 데는 한계가 있다. 이 경우 수치모델링 기법을 대안으로 적용할 수 있으나, 수치모델링은 수면에서 충격파의 전파와 수중에서 토석류의 전파를 동시에 모의해야 하고, 뉴턴 유체와 비뉴턴 유체의 특성을 동시에 고려해야하므로 수치해석 연구자들에게는 하나의 큰 도전사항이다. 이 연구는 경계면 포착기법을 이용한 계산유체동력학 기법을 이용하여 사면활동과 이로 인한 정지 수역에서의 충격파의 발생 및 전파를 재현하기 위한 수치 모델링 기법을 개발하는 것이 목적이다. 사면활동과 수면의 경계면을 포착하고 위치를 정립하기 위해서 VOF (volume of fluid) 경계면 재구축 기법을 이용한다. 지배 방정식은 비압축성(incompressible) 질량 보존방정식과 나비어-스톡스(Navier-Stokes) 방정식이며, 서로 다른 유체의 상(phase)애 대한 체적분할이송방정식을 이용한다. 큰와 모의 계열의 난류 모델링 기법을 적용하여 충격파의 전파와 붕괴에 대한 난류의 영향을 고려하였다. 토석류는 비뉴턴 흐름저항 관계식을 적용하여 그 흐름특성을 재현하였다. 이들 지배방정식은 2차 정확도의 유한체적법(finite volume method)을 이용하여 해석한다. 외국의 연구자들이 관측하여 제시한 길이 11 m 그리고 폭 0.5 m의 수로에서 발생한 충격파를 수치적으로 재현하여 개발된 모형의 실제 문제에 대한 적용성을 보여준다.

• Sleep Medicine and Psychophysiology
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• v.16 no.1
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• pp.16-21
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• 2009

In accordance with the development of EEG and polysomnography in the field of sleep research, the sleep onset period (SOP) between wakefulness and sleep has been considered an important part for understanding the physiology of sleep. SOP in the transition from wakefulness to sleep is a gradual process integrating various viewpoints such as behavior, EEG, physiology and subjective report. Particularly, based on understanding of EEG changes during sleep, SOP has been regarded as a pattern of topographical change in specific frequency and specific state in EEG. Studies on quantitative EEG (qEEG) and event-related potential (ERP) have suggested that SOP shows the changes of functional coordination at the specific cortical areas in qEEG and the changes of regular patterns in response to environmental stimulation in ERP. The development of sleep EEG and topographic mapping of EEG is expected to integrate various viewpoints of SOP and clarify the neurophysiologic mechanism of SOP further.

• Sleep Medicine and Psychophysiology
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• v.1 no.2
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• pp.163-171
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• 1994

Objectives: Symptoms of sleep apnea consisted of insomnia, excessive sleepiness during daytime, impaired cognitive functions and emotional disturbances. It was not so well known how these symptoms are correlated with various parameters of sleep and respiration, and what kind of psychophysiological processes are involved in development of these symptoms. Methods: In sixty patients with sleep apnea, sleep and respiration were studied by polysomnography of one night, also symptoms of sleep apnea were evaluated with the scales of insomnia, daytime sleepiness, emotional disturbance and cognitive impairment We studied correlations between apnea symptoms, and various parameters of sleep and respiration such as sleep efficiency, number severity of apnea, $O_2$ desaturation and number of snoring. Results: The result showing significant correlations are as follows. The patients with better sleep in insomnia scale showed more number of apnea, particularly more central type, and much more snoring in stage 3 sleep and mild desaturation of $O_2$. Excessive sleepiness during daytime correlated significantly with stage 1 sleep and its snoring, but correlated negatively with stage 2 sleep. However, no significant correlation was found with degree of $O_2$ desaturation. Emotional disturbance was more apparent in the patients with severe $O_2$ desaturation and smaller amounts of stage 4 sleep. Cognitive function was more impaired in cases of more REM sleep and less apnea. Conclusions: Symptoms of sleep apnea may occur through different causes and processes. The evaluation of apnea symptoms may be helpful to understand in some degree the condition of sleep and respiration during sleep in clinical setting.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.54-58
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• 2015

인간이 생활하는데 필요한 전기를 생산하는 시설 중 하나인 화력발전소의 발전수차를 냉각시키기 위하여 많은 양의 냉각수를 바다에서 취수하게 되는데, 이 과정 중에서도 특히 흡입수조(Intake Basin)에서 흡입펌프(Suction Pump)를 통과하는 단계가 매우 중요하다. 흡입수조의 형상과 펌프운용조건 등에 의하여 흡입구(Bell Mouth)에 접근하는 유동이 비대칭일 경우 흡입구 주변에서 선회류가 발생하거나 유속분포가 비균일?비대칭이 되기 쉽다. 그러면 선회류가 더욱 악화되어 볼텍스(Vortex)로 발달되면 취수 펌프에 악영향을 준다. 또한 볼텍스의 발생은 흡입수조의 형상뿐만이 아니라 낮은 수위일 경우 수면과 흡입구의 거리가 짧아지면서 자유수면볼텍스 또는 수중볼텍스가 발생할 확률이 높아지게 된다. 본 연구에서 수리모형시험을 통하여 펌프 조합 및 수위 변화에 따른 볼텍스의 발생여부를 파악하고 볼텍스 저감장치를 고안하였다.

• Korean Journal of Biological Psychiatry
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• v.19 no.1
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• pp.65-69
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• 2012

Objectives : Much is still unknown about the neurophysiological mechanisms or dynamics of the sleep onset process. Detrended fluctuation analysis (DFA) is a new tool for the analysis of electroencephalography (EEG) that may give us additional information about electrophysiological changes. The purpose of this study is to analyze long-range correlations of electroencephalographic signals by DFA and their changes in the sleep onset process. Methods : Thirty channel EEG was recorded in 61 healthy subjects (male:female=34:27, age=$27.2{\pm}3.0$ years). The scaling exponents, alpha, were calculated by DFA and compared between four kinds of 30s sleep-wakefulness states such as wakefulness, transition period, early sleep, and late sleep (stage 1). These four states were selected by the distribution of alpha and theta waves in O1 and O2 electrodes. Results : The scaling exponents, alpha, were significantly different in the four states during sleep onset periods, and also varied with the thirty leads. The interaction between the sleep states and the leads was significant. The means (${\pm}$ standard deviation) of alphas for the states were 0.94 (${\pm}0.12$), 0.98 (${\pm}0.12$), 1.10 (${\pm}0.10$), 1.07 (${\pm}0.07$) in the wakefulness, transitional period, early sleep and late sleep state respectively. The mean alpha of anterior fifteen leads was greater than that of posterior fifteen leads, and the two regions showed the different pattern of changes of the alpha during the sleep onset periods. Conclusions : The characteristic findings in the sleep onset period were the increasing pattern of scaling exponent of DFA, and the pattern was slightly but significantly different between fronto-temporal and parieto-occipital regions. It suggests that the long-range correlations of EEG have a tendency of increasing from wakefulness to early sleep, but anterior and posterior brain regions have different dynamical process. DFA, one of the nonlinear analytical methods for time series, may be a useful tool for the investigation of the sleep onset period.

• Sleep Medicine and Psychophysiology
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• v.11 no.1
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• pp.50-54
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• 2004

The obstructive sleep apnea syndrome can occur due to various etiologies in children. In otherwise healthy children, adenotonsillar hypertrophy is the leading cause of childhood obstuctive sleep apnea. Obstructive sleep apnea caused by adenotonsillar hypertrophy can lead to a variety of symptoms and sequelae such as behavioral disturbance, enuresis, failure to thrive, developmental delay, cor pulmonale, and hypertension. So if obstructive sleep apnea is clinically suspected, proper treatment should be administered to the patient after diagnostic examinations. More than 80% improvement is seen in symptoms of obstructive sleep apnea caused by adenotonsillar hypertrophy in children after tonsillectomy and adenoidectomy. However, when it is impossible to treat the patient using surgical methods or residual symptoms remained after tonsillectomy and adenoidectomy, additional treatments such as weight control, sleep position change, and continuous positive airway pressure (CPAP), should be considered. This paper reports a case using weight control and Auto-PAP to control mild sleep apnea and snoring, which in long-term follow-up were not resolved after tonsillectomy and adenoidectomy for severe obstructive sleep apnea.

• Korean Journal of Clinical Laboratory Science
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• v.47 no.3
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• pp.97-104
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• 2015

Sleep is not only an essential physiological function, but also serves important roles in promoting growth, maturation, and overall health of humans. There is increasing interest regarding the impact of sleep and its disorders on the regulation of inflammatory processes and end-organ morbidities, particularly in the context of metabolic and cardiovascular diseases (CVD) and their complications. Obstructive sleep apnea syndrome (OSAS) is an increasingly common health problem in children. In the last decade, the emergence of increasing obesity rates has further led to remarkable increases in the prevalence of OSAS, along with more prominent neurocognitive, behavioral, cardiovascular and metabolic morbidities. Although the underlying mechanisms leading to OSAS-induced morbidities are likely multifactorial and remain to be fully elucidated, activation of inflammatory pathways by OSAS has emerged as an important pathophysiological component of the end-organ injury associated with this disorder. To this effect, it would appear that OSAS could be viewed as a chronic, low-grade inflammatory disorder. Furthermore, the concurrent presence of obesity and OSAS poses a theoretically increased risk of OSAS-related complications. In this study, we will critically review the current state of research regarding the impact of insufficient and disrupted sleep and OSAS on the immune processes and inflammatory pathways that underlie childhood OSAS as a distinctive systemic inflammatory condition in children, and will explore potential interactions between OSAS and obesity.

• Journal of Wetlands Research
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• v.13 no.2
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• pp.199-208
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• 2011

Scarcity of water worldwide, increasing greenhouse gas emissions, increased energy consumption due to the Earth is threatened. Existing in the process of urban planning and development of forests, rivers and other natural ecosystems have been destroyed and that there was increased impervious pavement. Impervious pavement increase water circulation system to destroy the natural and urban water retention, infiltration and decreased evaporation. Nonpoint source pollution(NPS) occurs when rainfall impervious pavement and appeal directly to the river water inflow is adversely impacts of the situation. In this study, rainfall occurs impervious pavement NPS pollution reduction and temperature increase due to the increase in urban areas, and to solve heat island phenomenon is to develop small HSSF constructed wetland technology. The small HSSF constructed wetland sedimentation, filtration, adsorption, absorption by vegetation, including such mechanisms. Techniques for verification of the pilot-scale test was conducted. In the future domestic urban heat island phenomenon and restore the natural water cycle for the facilities will be used as a basis to develop.

• Journal of the Korea Convergence Society
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• v.12 no.7
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• pp.337-347
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• 2021

This study sought to determine whether there were mediating effects on both mental health and sleep problems as induced by COVID-19 fears and its effects on preventive practices. The participants were 310 adults living in the Seoul/Gyeonggi Province. For data collection, an online survey was conducted using a semi-structured questionnaire. The collected data were analyzed using PROCESS Macro (Model 6) to validate the dual mediating effects. This study analyzed the direct effects of COVID-19 fears on the mental health problems, sleep problems and preventive practices. Both mental health and sleep problems had dual mediating effects in the influence of COVID-19 fears on preventive practices. Preventive practice has shown that the mediated effects of mental health problems play a strong role in instances when COVID-19 fears increase.