• Water for future
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• v.28 no.5
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• pp.141-150
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• 1995

An air chamber is designed to keep the pressure from exceeding a predetermined value, or to prevent low pressures and column separation. Therefore, it can be used to protect against rapid transients in a pipe system following abrupt pump stoppage. In this research, an air chamber was applied to a hypothetical pipe system to analyze attenuation effect of pressure head for different air volumes, locations, chamber areas, coefficients of orifice loss and polytropic exponents. With an increase of air volume, the maximum pressure head at pump site is decreased and the minimum pressure head is increased. For different locations and areas of the chamber, the attenuation effects do not show much difference. Also, as the orifice loss coefficient increases, the maximum pressure head is decreased. For different polytropic exponents, isothermal process shows lower maximum pressure head than that of the adiabatic process.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2001.09a
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• pp.31-34
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• 2001

지하 LPG 저장기지의 수벽시설이 저장공동 주변 암반에 미치는 영향을 진단하기 위해서 수벽시설의 주입압력을 강하시키면서 간극수압계와 관측공에서의 지하수두 변화를 모니터링하였다. 수벽시설의 관측지점에 대한 효율성은 수치해석으로부터 수벽시설과 관측지점간 매질의 확산능을 구함으로써 분석하였다. 확산능 산출결과를 검증하기 위해서 수벽시설의 압력강하에 따른 관측지점에서의 수두강하비와 수두강하율을 구하여 확산능 결과와 비교하였다. 비교결과, 확산능은 수두강하비, 수두강하율과 일관된 변화를 보여주었으며 확산능의 값이 클수록 수벽공의 압력변화에 따른 관측지점에서의 반응성이 양호함을 나타내었다

• Pediatric Infection and Vaccine
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• v.22 no.2
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• pp.55-62
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• 2015

Purpose: Varicella Zoster Immune Globulin (VZIG) is available in Korea for post-exposure prophylaxis of the Varicella-zoster virus (VZV) in high-risk patients. In July 2013, the United States Centers for Disease Control and Prevention (US CDC) recommended extending the time for administration of VariZIG$^{(R)}$ from within 96 hours up to 10 days after VZV exposure. This study was performed to analyze the effectiveness of VZIG prophylaxis between the two groups of patients who received VZIG within 96 hours and more than 96 hours of exposure to varicella. Methods: A retrospective chart review was performed in pediatric patients who received VZIG at Samsung Medical Center, Seoul, Korea from January 2001 to December 2012. Results: A total of 91 patients were identified. Fifty-seven patients were male (62.6%) and the median age was 5.91 years. Thirty-nine patients (42.9%) were exposed to VZV in the hospital. Underlying diseases were solid tumors (41.8%), hematologic malignancies (40.7%), and others (17.5%). Forty-five patients (49.5%) were hematopoietic cell transplant recipients. Seventy-four patients (81.3%) received VZIG within 96 hours after VZV exposure. There was no significant difference in the development of chickenpox between the two groups (2.7% vs. 5.9%, P=0.4664). In 22 seronegative patients, we also observed no significant difference between the groups in terms of the development of chickenpox (6.6% vs. 0%, P=0.667). Conclusions: This study showed that the effectiveness of VZIG for the prevention of chickenpox was comparable between patients who received VZIG within 96 hours and those who received VZIG more than 96 hours after exposure to VZV.

• Clinical and Experimental Pediatrics
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• v.52 no.5
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• pp.607-610
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• 2009

Varicella zoster virus (VZV) causes two diseases: Varicella, a generalized, primary infection, and herpes zoster (zoster), a secondary infection caused by latent VZV reactivation. Zoster can also be caused by latent VZV reactivation after a varicella vaccination. The complications associated with varicella include cutaneous infections, which are the most common, as well as pulmonary and neurological involvement. However, a deep venous thrombosis (DVT) has been rarely described as a varicella-associated complication. Here, we describe the case of a child with varicella zoster who developed a DVT that completely resolved after intravenous acyclovir and subcutaneous low-molecular-weight heparin treatment.

• KSBB Journal
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• v.9 no.3
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• pp.272-278
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• 1994

Attenuated varicella-zoster virus(VZV) was cultured in human embryonic lung cells. The effects of serum type and its concentration on the production of VZV were studied. Regardless of cell culture conditions, VZV yield was increased with multiplicity of infection, and the total cell concentration was decreased after virus infection. The newborn calf serum, calf serum, or horse serum was not as good as the fetal bovine serum or calf serum supplemented with iron for the propagation of VZV in the human embryonic lung cells. The yields of total VZV(cell-associated virus and cell-free virus) in the medium with calf serum containing iron were comparable to those in the medium supplemented with fetal bovine serum. Furthermore, some components of serum appear to be important for the maintenance of VZV infectivity.

• Journal of the Korean Society of Groundwater Environment
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• v.2 no.1
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• pp.30-37
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• 1995

In the tidal compartment, the hydraulic head is affected by the stage of tidal rivers. For groundwater or construct works, head variation of groundwater should be considered in zone of this aquifer. A numerical analysis is performed which has an 1-dimemsional explicit finite difference scheme to show the head variation of groundwater with tidal stage and hydraulic conductivity, etc. The stability of the numerical scheme is validated by using the analytic solution. The head variation of groundwater is observed for various tidal amplititude and hydraulic conductivity, mean hydraulic gradient and pumping at any point. The range of influence corresponding to the parameters used in this study is about 60m. This value is not beyond a wave length (equation omitted). There was a pumping at a constant rate out of aquifers affected by tide and not affected by tide. Because pumping head in aquifer affected by tide is short, the expense of electric power is economized in this zone. These results are applicable to trace of contaminant transport, efficient operation of groundwater, and examination of the safety and stability of works in the tidal compartment.

• Pediatric Infection and Vaccine
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• v.7 no.1
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• pp.129-135
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• 2000

Purpose : We previously reported the short-term immunogenecity and safety of 47 passaged Oka strain live attenuated varicella vaccine in healthy children in 1997. Now, we conducted this two-year follow-up study to confirm the maintenance of immunity, the occurrence of natural varicella infection and the activation of vaccine induced latent infection on the same vaccine. Methods : 99 children who had been immunized by 47 passaged Oka strain live attenuated varicella vaccine in 1997 were followed up by questionnaire, and 46 children out of study group were followed up serologically. They were asked to report any instance of varicella or herpes zoster since they had been immunized. If there was any evidence of varicella or herpes zoster, they should be clinically or serologically confirmed by doctor. Also, those patients' parents were asked to report any instance of varicella or herpes zoster in their family, playmate, kindergarten, school, or other settings. The immunity to VZV was confirmed by EIA and FAMA test. Results : 6 recipients developed breakthrough varicella after exposure to VZV in family, kindergarten and school during follow-up period. However, clinical features of those patients were very mild and self limited without therapy. And none of the recipients developed herpes zoster during this observation period. The results of EIA test showed that study subjects were all seropositive except one, and the antibody titers and GMT of FAMA test were seropositively maintained in all subjects. Statistically, the antibody titers of EIA and FAMA test confirmed two years after vaccination were higher than those results confirmed one month after vaccination. Conclusion : Our study results suggest that the immunity of 47 passaged Oka strain live attenuated varicella is well maintained until 2 years later after vaccination, and mild natural infection after exposure to VZV can be occurred with low rate. There were not developing zoster in study vaccine after vaccination for two-years.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2003.09a
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• pp.601-604
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• 2003

방사성폐기물 처분 연구의 일환으로 화강암지역내 500m 심도의 심부시추공이 착정되었으며, 다중패커시스템이 설치되어 장기적으로 심도별 지하수의 수리 및 화학특성이 모니터링 되고 있다. 지하수 수두값의 심도별 특성은 천부에서 심도 250m까지는 대체로 감소하는 경향을 보이며 250m이하에서 500m 심도까지는 증가하는 경향을 보여준다. 각 심도구간에서의 지하수 수두값은 장기적으로 일정한 값을 보여주지만, 장마기간동안 집중적으로 모니터링된 결과에 따르면 심도 370m 상부에서는 지하수 함양변화에 따라 지하수 수두가 변화되는 반면, 심부구간에서는 지하수 함양변화에 대하여 영향을 받지 않음을 보여준다.

• Pediatric Infection and Vaccine
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• v.5 no.1
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• pp.88-95
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• 1998

Purpose : Varicella is a common contagious illness and vaccine against it has been used in healthy Korean children. We studied clinical and epidemiologic features of varicella and the effect of vaccination. Methods : We analyzed clinical and epidemiologic features of varicella and vaccination effect against it in children treated in Hangang Sacred Heart Hospital from March 1994 to December 1996. Results : 1) Total 73 cases of varicella, 46 male and 27 female patients were included. Annual incidence was 31, 20 and 22 cases from '94 to '96 respectively, with an increase during the period June to July and December to January. 2) Mean age was $46{\pm}37.2$ months and 84.9% of the patients were younger than 7 years old including 16.4% of infants. 3) Varicella occurred after a contact with varicella patients in 40(54.8%) patients. 4) Fever developed in 44(60%) patients with mean $38.4{\pm}0.8^{\circ}C$ and persisted for mean $3{\pm}2.4$ days. Nine(12.3%) patients had complications and eighteen(25%) patients were admitted for mean $4{\pm}2.1$ days but all recovered. 5) Twenty(27.8%) patients were affected despite preceding vaccination against varicella but the number of vesicles decreased significantly in vaccinees(P<0.01). 6) The rate of secondary cases in healthy siblings was 27 out of 35(77.1%) and was not affected by preceding vaccination. Conclusion : Varicella occurred mainly in children younger than 7 years old and showed seasonality. Because 27.8% of cases developed despite preceding vaccination and the rate of secondary cases was not affected by vaccination, further study for vaccine efficacy is necessary.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.5 no.3
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• pp.71-84
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• 1985

Using a saturated-unsaturated transient flow equation the change of hydraulic heads within a dike due to tidal fluctuation is investigated in this study. The calculation is done by the use of a software computer program called FLUMP, which is based on a FEM technique and useful to the analyses of unsaturated flow problems. Some of the program has been supplemented in this study for the application to the rise of a tide. It is assumed that a dike is composed of two materials, that the tide rises and falls with a constant amplitude of 10 meters, and that water tables are located at 0m, 5m, and lam from the minimum tidal level. For these conditions the hydraulic heads are calculated for 8 cycles(96 hours) of tidal changes. It is known from the analysis that the hydraulic heads change with tidal level in some extent and that the amplitudes of the head varies depending on the location within the dike: the maximum amplitude shows near the toe of the dike, the amplitude decreases with increasing distance from the upstream face, and beyond a certain location the heads are unaffected by the tidal differences. Assuming that the dike has been completed in a moment the hydraulic heads are nearly stabilized in 96 hours towards some constant values corresponding to a specified water table.