• Clinical and Experimental Pediatrics
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• v.52 no.7
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• pp.824-831
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• 2009

Purpose : We aimed to investigate the efficacy of and functional recovery after intracerebral transplantation of different doses of mouse mesenchymal stem cells (mMSCs) in immature rat brain with hypoxic-ischemic encephalopathy (HIE). Methods : Postnatal 7-days-old Sprague-Dawley rats, which had undergone unilateral HI operation, were given stereotaxic intracerebral injections of either vehicle or mMSCs and then tested for locomotory activity in the 2nd, 4th, 6th, and 8th week of the stem cell injection. In the 8th week, Morris water maze test was performed to evaluate the learning and memory dysfunction for a week. Results : In the open field test, no differences were observed in the total distance/the total duration (F=0.412, P=0.745) among the 4 study groups. In the invisible-platform Morris water maze test, significant differences were observed in escape latency (F=380.319, P<0.01) among the 4 groups. The escape latency in the control group significantly differed from that in the high-dose mMSC and/or sham group on training days 2-5 (Scheffe's test, P<0.05) and became prominent with time progression (F=6.034, P<0.01). In spatial probe trial and visible-platform Morris water maze test, no significant improvement was observed in the rats that had undergone transplantation. Conclusion : Although the rats that received a high dose of mMSCs showed significant recovery in the learning-related behavioral test only, our data support that mMSCs may be used as a valuable source to improve outcome in HIE. Further study is necessary to identify the optimal dose that shows maximal efficacy for HIE treatment.

• Journal of the korean academy of Pediatric Dentistry
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• v.35 no.2
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• pp.333-338
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• 2008

Supernumerary teeth are characterized by an excess number of teeth, which can be responsible for a variety of irregularities in the primary and transitional dentition. Supernumerary teeth, especially in the maxillary anterior region, may prevent the eruption of adjacent permanent teeth and cause their ectopic eruption, diastema, root resorption, or formation of dentigerous cyst. Therefore, early diagnosis of supernumerary teeth is important for prevention of such complications, and adequate treatment should be given according to their location, number, and morphologic features. In this case, four supernumerary teeth in the maxillary anterior region were disturbing the eruption of adjacent permanent incisors. Two of them were located in proximity to the central incisor tooth germs that their immediate removal may injure the permanent tooth germs. In order to minimize such complications, surgical extraction of the four supernumerary teeth was performed in two stages. At first, only two inverted conical supernumerary teeth were extracted. The other two tuberculous supernumerary teeth, close to the permanent tooth germs, were extracted later after their natural dislocation. In that way, we could minimize affects on the neighboring permanent tooth germs and also the amount of alveolar bone removed during surgery.

• Journal of Korean Ophthalmic Optics Society
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• v.7 no.2
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• pp.229-234
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• 2002

The human eye and skin is exposed daily to solar energy. Expecially, the ultraviolet radiation (UVR) exposure has been damaged as an important causative factor in corneal disease. These damage of cornea was effected the retina. Therefore the eye function was effected very significant damage. As a results the protect of UVR in the eye is very important in ocular health. Therefore in living the intensive ultraviolet radiation environment by solar energy, human eye have protected the cornea and eyeball by the UV-blocking sunglass, eyeglass, goggles, and contact lens. Finally the specific UV-blocker lens devices available to the primary care for the subjects by optician. Of course, in the future these specific lenses have to development and study by fellowship.

• Journal of Advanced Marine Engineering and Technology
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• v.35 no.4
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• pp.460-467
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• 2011

Cavitation phenomena during the spill process of the Bosch type fuel injection pump for medium-speed diesel engine were investigated by optical observations. Typically, these phenomena can cause a surface damage with material removal or round-off at the plunger and barrel port etc., and may shorten their expected life time. The images, which were recorded with high speed CCD camera and borescope, show that the plunger damage is mainly affected by fountain-like cavitation generated before the end of delivery. And the damages of barrel port and deflector are caused by jet-type cavitation generated after end of delivery.

• Journal of the Korea Concrete Institute
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• v.21 no.2
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• pp.129-138
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• 2009

Recently, for more demands of the economical benefits and environmental conservation, many engineers prefer to choose remodeling. Artificial openings are often unavoidable to make house wider, which will degrade wall strength and stiffness by losing effective wall section that may cause the weakening of system capacity. In these cases the damaged shear walls need to be retrofitted by additional materials or members. In this research, four specimens were tested to investigate the capacity of the damaged wall and the retrofitted wall. The artificially damaged wall was prestressed by tendons to improve the shear capacity of the wall, and the other walls were retrofitted by adding steel plate at the surface for the same purpose. Consequently, these retrofitted walls had improved capacity and stiffness in both shear and flexure. Especially, the wall with steel plate showed ductile behavior after ultimate load and the prestressed wall had greater stiffness than the unstrengthened prototype wall.

• Physical Therapy Korea
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• v.8 no.4
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• pp.17-29
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• 2001

발목에 대한 유착성 테이핑의 적용은 물리치료 분야와 운동 트레이닝 분야에서의 일반적인 치료 접근 방법이라 할 수 있다. 즉 발목 염좌 같은 손상을 예방하기 위한 방법과 재활의 부가적인 치료 형태로 이용될 수 있는 것이다. 본 연구는 발목의 테이핑과 트레드밀에서의 30분간 보행이 수직 착지 동작 동안 하지의 운동 역학적 요소들에 어떠한 영향을 주는지 알아보기 위해 시행되었다. 14명의 신체 건강한 대상자들 (남:10, 여:4)이 본 연구에 참여하였다. 한발로 서있는 동안 40 cm의 높이로 뛰게 하였다. 가자미근, 전경골근, 안쪽넓은근, 넙다리 두갈래근에 근전도 전극이 부착되었다. 테이핑된 신체 부위로 착지하는 동안 근전도와 힘판(force plate) 자료가 500 Hz의 주파수로 수집되었다. 대상자들의 우세쪽 하지 발목에 테이핑을 하였고, 대상자는 한발로 뛰어 내리는 동작을 반복하였다. 트레드밀에서 30분 동안 발목에 테이핑을 한 채로 보행하였고 이후 한발로 뛰어 내리는 동작을 반복하여 수행하였다. 테이핑을 적용한 상태와 테이핑한 채로 30분 동안 트레드밀에서 걷기 운동을 한 조건에서 수직 지면 반발력의 통계학적으로 유의미한 증가가 있었다. 착지 동안에 네 가지 상황에서의 최대 내측 가속도의 유의한 차이가 있었고, 그 차이는 테이핑 전과 테이핑을 한 채로의 운동 조건에서 유의한 차이가 있었다. 테이핑한 상태에서 가자미근은 접촉되는 착지 순간부터 최대 수직 지면 반발력이 나타나는 동안의 평균 근전도의 수치에 있어서 유의한 감소가 있었다. 반면에 다른 근육들에서는 아무런 변화를 보이지 않았다. 비록 발목 테이핑이 발목 손상의 위험을 줄이는데 효과적이라고 일반적으로 인식되고 있으나 이번 실험의 결과는 30분 동안의 트레드밀에서의 보행 후 테이핑은 발목의 움직임을 제한하는 효과는 있지만 한편으로는 가자미근의 활동을 감소시키는 것을 보여주었다. 따라서 이 연구의 결과는 테이핑을 하면 점프와 착지로 이어지는 동작 중에 발목관절 손상 위험을 증가시킬 가능성이 있음을 보여주었다.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.25-31
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• 2019

Because of its physical characteristics, earthquake has a great impact on a wide area in a short time, so it needs a resilience based seismic countermeasures to restore the community function. For this reason, in this study, the seismic damages of urban buildings were assessed stochastically by virtual earthquakes using public data information and disaster management program(Ergo-EQ). A geographical map reflecting geological characteristics of the target area was created with the buildings and topographic data in Dalseo-gu, Daegu City. In addition, an integrated database including building characteristics was modified to be linked with the Ergo-EQ program. The seismic damages for the buildings were evaluated through the exceedance probability of four different damage levels. From the damage results, it can be identified not only the seismic damage of each building, but also the major factors affecting earthquake damage.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.293-296
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• 2001

MPEG-2 압축 방법을 이용한 비트열은 가변장 부호를 이용하기 때문에 에러에 매우 민감하다. 하나의 비트에러가 발생하더라도, 다음 동기화 부호를 찾을 때까지 매크로블록 또는 슬라이스 단위의 정보 손실을 초래하기 때문에 복원 영상의 화질 열화가 심각하다. 따라서 에러 영상의 복원을 위한 에러 은닉 기술은 복호기 쪽에 매우 중요하다. 기존에 발표된 방법들은 에러에 의한 손실이 매크로블록 단위로 발생했다는 가정 하에 손상된 매크로블록주위의 상, 하, 좌, 우 네 방향의 데이터를 이용하였다. 하지만 대부분의 심각한 에러는 슬라이스 단위로 발생하기 때문에 좌, 우의 데이터는 사용할 수 없다. 본 논문에서는 이러한 슬라이스 단위의 에러를 은닉하기에 적합한 알고리즘을 제안한다. 상, 하, 오른쪽 상단, 왼쪽 상단, 오른쪽 하단, 왼쪽 하단의 6영역의 데이터를 이용하여 두 가지 대표적인 에러 은닉 방법인 boundary matching 방식과 주변 움직임 벡터 정보를 이용한 움직임 벡터 추정 방식에 적용하였다. 실험 곁과 기존의 방법에 비해 향상된 복원 화질을 얻을 수 있었다.

• CORROSION AND PROTECTION
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• v.12 no.1
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• pp.1-11
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• 2013

Alloy 600 재료의 PWSCC의 개념을 소개하고 그 발생과 전파에 미치는 미세조직, 온도, 응력, 수화학 환경등의 주요인자를 정리하였다. ◯ PWSCC란 니켈 기지 합금인 Alloy 600와 그 용접재인 Alloy 82/182 재료가 원자로 1차수 환경에서 보이는 응력부식균열을 의미한다. ◯ Alloy 600의 PWSCC에 미치는 주요 인자에는 재료의 미세조직, 응력, 온도, 환경등이 있으며 그 중에서 재료의 미세조직이 가장 지배적인 인자이다. ◯ 재료내의 탄화물은 탄소 함량과 열처리 조건에 따라 달리 형성되며 입계를 따라 준연속적으로 잘 발달된 입계탄화물을 가지는 재료가 PWSCC에 저항성을 가진다. ◯ 손상속도는 부가 응력의 네 제곱에 비례하여 증가하는 것으로 알려져 있다. ◯ PWSCC는 Arrhenius 관계의 열활성화 과정(thermally activated process)이다. ◯ 용존수소량에 따라 재료의 부식전위가 정해지는데 전극전위가 Ni/NiO 평형전위 부근에서 가장 큰 균열 성장 민감도를 보인다는 데는 연구자들 사이에 이견이 없다. 그러나 균열의 개시에 대한 용존수소량의 영향에 대해서는 이견이 있다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.12
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• pp.1628-1632
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• 2007

The present study describes the preliminary evaluation of antioxidant activities and antigenotoxic effect of Rhododendron mucromulatum Turcz. flowers (RMF). The samples were prepared by extracting RMF with four different solvents (methanol, ethanol, acetone, and water), and antioxidant properties were evaluated by determining total phenolic contents (TPC), DPPH radical scavenging activity (RSA), and reducing power (RP). Water extract showed the highest total phenol content (328.1 mg/g gallic acid equivalents). Acetone extract showed the most potent RSA and RP. The $IC_{50}$ for RSA and RP in the acetone extract were 78 mg/mL and 454 mg/mL, respectively. The 200 mM $H_2O_2$ induced DNA damage, measured by Comet assay, was inhibited with water, methanol and acetone extract in dose dependent manner in human leukocytes. The inhibition rates were 42, 62, and 52% at the concentrations of 50 mg/mL of water, methanol and acetone extracts, respectively. These results suggest that R. mucromulatum Turcz. has significant antioxidative activity and protective effect against oxidative DNA damage.