• Title/Summary/Keyword: 손상합

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Protective effect of Korean diet food groups on lymphocyte DNA damage and contribution of each food group to total dietary antioxidant capacity (TDAC) (한식 식품군의 in vitro 총 항산화능 (TDAC)과 ex vivo DNA 손상 보호효과와의 관련성)

  • Lee, Min Young;Han, Jeong-Hwa;Kang, Myung-Hee
    • Journal of Nutrition and Health
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    • v.49 no.5
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    • pp.277-287
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    • 2016
  • Purpose: This study was performed to compare total phenolic contents, in vitro antioxidant capacity, and reduction effect of Korean food groups on ex vivo DNA damage in human cells and analyze correlations between each indicator. Methods: Vegetable foods in the Korean diet based the results of the KNHANES V-2 (2011) were classified into 10 food groups: cereals, fruits, vegetables, nuts, kimchi, seaweeds, potatoes, mushrooms, legumes, and oils. Eighty-four foods constituted more than 1% of the total intake in each food group and finally designated as vegetable foods in the Korean diet. Total phenolic content of each food group was measured. Further, in vitro antioxidant capacity was measured based on DPPH radical scavenging assay, TEAC assay, and $ORAC_{ROO{\cdot}}$ assay. Ex vivo DNA damage in human lymphocytes was assessed using comet assay. Results: Total phenolic contents of food groups of the Korean diet increased in the order of mushrooms, fruits, vegetables, seaweeds, and kimchi. Meanwhile, antioxidant rankings of food groups as mean values from the three in vitro test methods increased in the order of mushrooms, seaweeds, vegetables, kimchi, and fruits. Protection against ex vivo DNA damage in human lymphocytes was highest in mushrooms, followed by vegetables, fruits, seaweeds, and kimchi. The rankings of the food groups for total phenolic content, in vitro DAC, and ex vivo DNA protection activity were similar, and correlations between each indicator were significantly high. Conclusion: Mushrooms, fruits, vegetables, and seaweeds among the tested food groups in the Korean diet showed high total phenolic contents, in vitro antioxidant capacities, and protection against DNA damage. Correlations between each indicator in terms of total phenolic content, in vitro antioxidant capacity, and ex vivo DNA protection between each food group were found to be particularly high.

Arthroscopically assisted Operative Treatment of Tibial Plateau Fracture (관절경을 이용한 경골 고평부 골절에 대한 수술적 치료)

  • Byun, Jae-Yong;Kim, Bo-Hyun;Kang, Shin-Taek;Whang, Chan-Ha
    • Journal of the Korean Arthroscopy Society
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    • v.10 no.1
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    • pp.45-52
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    • 2006
  • Purpose: We evaluated the results of operative treatment of tibial plateau fractures using both arthroscopy and fluoroscopy. Materials and Methods: From May 1999 to February 2003, tibial plateau fractures were treated with arthroscopy. Tweenty seven patients are followed up over two years and the average follow-up period was fourty one months. We classified the fractures according to the Schatzker classification. We reduced the fracture over 2mm depression and displacement on articular surface in simple radiologic finding. Firstly, we treated the associated injuries and reduced the fractures using Steinmann pins. Then, we accomplished internal fixation or external fixation. Both the postoperative clinical and radiological results were evaluated by Rasmussen system. Results: In all tweenty seven cases, the fractures were healed completely in average fourty one months. According to Rasmussen classification, we obtained the excellent or good results in 23 cases. An average range of motion was between 2.5 degrees and 130 degrees. However, postoperative infection developed in one case and the other had loss of reduction. Conclusions: We consider that arthroscopically assisted operative treatment of tibial plateau fracture is a useful method. We can reduce joint surface correctly and treat associated injuries with arthroscopy. There are less complications.

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Clinical Observation and Treatment of Fracture-Dislocation of Talus (거골 골절 및 탈구의 임상적 고찰)

  • Lee, Dong-Chul;Kim, Se-Dong;Jung, Hae-Hoon
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.302-311
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    • 1992
  • Talus is a important structure of the ankle joint and its function is critical for ambulation and weight bearing. The talus fracture is rare, but the complications of fracture and dislocation are serious and resulting in avascular necrosis, osteoarthritis. So its treatment is carefully considered at initial status. Authors reviewed 11 cases of fracture and dislocation of the talus treated at Yeungnam university hospital from 1984 to 1991. The longest follow up was 8 years and shortest, 1 year. The results were as follows. 1. There were all males, the average age was 30 years old. 2. The most common cause was fall down(8 cases), and next traffic accident(2cases), sports injury(1 case). 3. According to Marti-Weber classification, 1 cases was type I, 1 in type II, 4 in type III and 5 in type IV. 4. The method of treatment were open reduction and internal fixation in 6 cases, the others were closed reduction in 5 cases. 5. Final results(by Hawkins grading system) were as follows, 3 cases were excellent, 4 cases were good, 1 case was fair and 3 cases were poor. 6. Complications were AVN in 2 cases, degenerative arthritis in 8 cases, malunion in 1 case. 7. The range of motion of the ankle joint was relatively preserved(74%), but in the subtalar joint it was decreased(43%).

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Investigation of Physical Property Change in Modified Rice Starch by Ultra Fine Pulverization (초미세분쇄를 이용한 쌀 변성전분의 물리적 특성 변화구명)

  • Han, Myung-Ryun;Chang, Moon-Jeong;Kim, Myung-Hwan
    • Applied Biological Chemistry
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    • v.50 no.3
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    • pp.160-166
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    • 2007
  • This study was performed to analyze the molecular structural and physical properties changes of modified rice starch, which particle structure was broken using high impact planetary mill and ultra fine pulverizing techniques. The average diameter and specific surface area of rice starch after pulverization decreased 20% and increased 25%, respectively. Low molecular substances content in rice starch using GPC (gel permeation chromatography) increased from 36.5% to 59.5% after pulverizing of rice starch. Damaged starch contents in rice starch also increased from 16.4% to 99.2% after pulverizing of rice starch. Water holding capacity, solubility and transmittance of rice starch after pulverization increased compared to those of control. Apparent viscosity value of rice starch after pulverization decreased to 7% in control based on $30^{\circ}C$ and 20 RPM conditions.

Peripheral Nerve Regeneration After Various Conditioned Side to Side Neurorrhaphy in Rats (말초신경 손상 후 측측문합을 이용한 신경이식시 신경이식의 수에 따른 신경재생 및 근육 기능 회복에 관한 비교 연구)

  • Kim, Sug-Won;Chung, Yoon-Kyu;Kang, Sang-Yoon;Cho, Pil-Dong
    • Archives of Reconstructive Microsurgery
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    • v.10 no.1
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    • pp.12-17
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    • 2001
  • Recovery of nerve injury is conditioned by various factors including physical state, injured site, cause of injury, and neurorrhaphy Many researchers have reported on regeneration of nerve using end to side neurorrhaphy. The purpose of this study was to examine regeneration of nerve in various conditioned side to side neurorrhaphy. Total of 25 male Sprague-Dawley rats weighing 220 to 250 gm were divided into five groups of five rats each. The group 1, sham group, composed of dissection only without nerve transaction. The group 2, control group, composed of nerve division only without neurorrhaphy or sural nerve graft. The group 3 composed of one segmental sural nerve graft between the tibial and peroneal nerve after division. Group 4 had two segment graft, and the group 5 with three segment graft, each segment being 6mm long and 5 mm apart. The side to side neurorrhaphy was performed between peroneal nerve and tibial nerve using segmental sural nerve graft in rats. We exposed the sciatic nerve, tibial nerve, peroneal nerve, and sural nerve on left side with prone position. The peroneal nerve was cut on the bifurcation site from tibial nerve and the side to side epineurial neurorrhaphy was performed between peroneal nerve and tibial nerve through 6 mm sural nerve segment graft with 11-0 nylon under operating microscope. The electromyography and the weight from ipsilateral tibialis anterior muscle was performed at one month after neurorrhaphy Peroneal and tibial nerve was examined at distal and proximal to the neurorrhaphy site by methylene blue stain under light microscope for histologic appearance. The number of nerve fibers were counted using the image analyzer. Statistically, both in electromyography and number of nerve fibers, the differences in values between the groups were significant.

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Three-Dimensional Container Packing Problem with Freight Priority (우선순위를 고려한 컨테이너 3차원 적재문제)

  • Bae, Min-Ju;Choi, Se-Kyoung;Kim, Hwan-Seong
    • Journal of Navigation and Port Research
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    • v.28 no.6
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    • pp.531-539
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    • 2004
  • In this paper, we propose a new heuristic solution for 3D container packing problem for the variable sizes and types of freight. Frist of all, we consider the total cost of container charge i.e., handling, loading and transportation, where each freight will be specifically identified The types of containers and its number to be loaded am be selected automatically by minimizing the total cost of container charge. Maximization of loading space am be achieved efficiently by operating the palletizing and/or depalletizing of freight. By considering these factors we can determine the position of freight in the container and the loading sequence to be packing into the container. In container packing simulation, we can verify that the proposed heuristic algorithm indicates more efficiency space utilization and shows the possibility of using on commercial business.

In vitro dffect of praziquantel on Paragonimus westermani by light and scanning electron microscopic observation (폐흡충에 대한 Praziquantel의 시험관내 작용에 관한 광학 및 연사전자현미경적 관찰)

  • 이순형;박호진
    • Parasites, Hosts and Diseases
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    • v.25 no.1
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    • pp.24-36
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    • 1987
  • The effect of praziquantel on P. westermani exposed in vitro was observed by stereomicroscope, light microscope and scanning electron microscope. Following results were found. 1. The worms incubated in $0.01{\;}{\mu}g/ml$ praziquantel were moving after 26-hour incubation. However, all of them were immobilized immediately after incubation in solutions over $0.01{\;}{\mu}g/ml$ concentration. 2. All of the exposed worms showed severe vacuolization not only in tegument but in subtegument, intestine, ovary, testis, Mehlis' gland and excretory bladder. 3. Vacuoles in tegument burst out to form craters. As incubation time went on, tegumental structure was disintegrated severely. The worms exposed to praziquantel were observed to be immobilized and be vacuolized of all tissues. Disintegration of reproductive organs suggests that praziquantel have suppressive effect on egg production when the flukes are not killed. The drug effects were found more related with incubation time than with drug concentration.

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Comparison of Urinary Tract Infections Caused by Escherichia coli and Non-E.coli in Infants (대장균과 비대장균에 의한 영아 요로 감염의 비교)

  • Joung, Jin-Kyo;Choi, Cheol-Soon;Kim, Seong-Joon;Park, So-Hyun;Kim, Jong-Hyun;Koh, Dae-Kyun
    • Pediatric Infection and Vaccine
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    • v.16 no.2
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    • pp.162-166
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    • 2009
  • Purpose : Urinary tract infection (UTI) is one of the most common bacterial infectious disease in childhood. Renal scarring is an important complication of UTIs. Known risk factors for renal scarring are younger age, anatomic defects, delayed treatment, and causative pathogens other than Escherichia coli. The aim of this study was to compare the characteristics of clinical and laboratory features of UTI with E. coli to those with non-E. coli in infants. Methods : We reviewed the medical records of 1,120 infants under 12 months of age who had been admitted for UTIs between January 1998 and December 2007. All patients who were diagnosed with UTIs were divided into two groups (E. coli and non-E. coli UTIs). Results : Three hundred twenty-four of 1,120 cases met the inclusion criteria. The number of E. coli and non-E. coli UTIs was 273 (84.3%) and 51 (15.7%), respectively. As compared to the non-E. coli UTI group, the E. coli UTI group was younger (3.59 vs. 4.47 months, P =0.008), a longer duration of pyuria (3.96 vs. 3.06 days, P =0.01), higher peripheral white blood cell counts (13.89 vs. $12.13{\times}10^3/mm^3$, P =0.043), and lower rates of high degree (III-V) vesico-ureteral reflux (P =0.005). Conclusion : UTIs with E. coli might have more severe clinical features and a lower prevalence of high grade vesicoureteral reflux than UTIs with non-E. coli. However, no difference was noted in the clinical response to antibiotic therapy between the two groups.

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A Object-Based Image Retrieval Using Feature Analysis and Fractal Dimension (특징 분석과 프랙탈 차원을 이용한 객체 기반 영상검색)

  • 이정봉;박장춘
    • Journal of Korea Multimedia Society
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    • v.7 no.2
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    • pp.173-186
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    • 2004
  • This paper proposed the content-based retrieval system as a method for performing image retrieval through the effective feature extraction of the object of significant meaning based on the characteristics of man's visual system. To allow the object region of interest to be primarily detected, the region, being comparatively large size, greatly different from the background color and located in the middle of the image, was judged as the major object with a meaning. To get the original features of the image, the cumulative sum of tile declination difference vector the segment of the object contour had and the signature of the bipartite object were extracted and used in the form of being applied to the rotation of the object and the change of the size after partition of the total length of the object contour of the image into the normalized segment. Starting with this form feature, it was possible to make a retrieval robust to any change in translation, rotation and scaling by combining information on the texture sample, color and eccentricity and measuring the degree of similarity. It responded less sensitively to the phenomenon of distortion of the object feature due to the partial change or damage of the region. Also, the method of imposing a different weight of similarity on the image feature based on the relationship of complexity between measured objects using the fractal dimension by the Boxing-Counting Dimension minimized the wrong retrieval and showed more efficient retrieval rate.

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Knee Joint Sparing Tumor Resection in 4years-Old Patient with Osteosarcoma - A Case Report - (4세 소아 대퇴골 골육종의 슬관절 보존형 절제 및 재건술 - 증례 보고 -)

  • Cho, Wan-Hyung;Cho, Sang-Hyun;Won, Ho-Hyun;Jeon, Dae-Geun
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.157-162
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    • 2008
  • Nowadays, most of the malignant bone tumor patient underwent limb salvage operation, however, reconstructive options for skeletally immature group are still controversial. There are three necessary conditions of most ideal reconstructive method in treating the skeletally immature children. As the epiphyseal plate sacrification is usually inevitable in malignant bone tumor around knee joint, ideal reconstructive technique would be as follows; 1)minimal or no damage to theadjacent epiphyseal plate, 2) maintaining mobile joint, 3) index procedure does not disturb subsequent operation such as lengthening. Segmental resection and reconstruction using autogenous pasteurized graft was done for 4 years old meta-diaphyseal osteosarcoma of femur. At 6 months from index operation, plain radiograph showed pasteurized bone resorption and loosening of fixation devise. To overcome the complication, we used allograft reconstruction by impacting the proximal host bone to the fluted portion of allobone. Three months later, proximal bone union was observed and patient showed good functional outcome.

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