• Title/Summary/Keyword: 손상경험

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Pamidronate therapy for a Patient with Methylmalonic acidemia (메틸말론산혈증 환자에서 파미드로네이트 치료 1례)

  • Cho, Sujin;Seo, Go Hun;Kim, Yoon-Myung;Kim, Gu-Hwan;Yoo, Han-Wook;Lee, Beom Hee
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.18 no.1
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    • pp.13-17
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    • 2018
  • Methylmalonic acidemia is an autosomal recessive disorder caused by complete (mut0) or partial (mut-) deficiency of methylmalonyl-CoA mutase (MUT) or by defects in the synthesis of adenosylcobalamin (cblA, cblB, cblD variant 2). Long term complications of methylmalonic acidemia include tubulointerstitial nephritis with progressive renal failure, intellectual impairment, pancreatitis, and growth failure. We report a case of methylmalonic acidemia in a girl who diagnosed at 6 days after birth. She has developed recurrent metabolic crises with hyperammonemia and metabolic acidosis. In addition, she suffered from the chronic complications including tubulointerstitial nephritis, electrolyte imbalance associated with renal dysfunction, growth failure and fracture of femur shaft. At the age of 10 years, hypercalcemia and severe osteoporosis were noted, and pamidronate therapy was given for two years, which relieved hypercalcemia and osteoporosis.

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The Extraction of Soil Erosion Model Factors Using GSIS Spatial Analysis (GSIS 공간분석을 활용한 토양침식모형의 입력인자 추출에 관한 연구)

  • 이환주;김환기
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.19 no.1
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    • pp.27-37
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    • 2001
  • Soil erosion by outflow of water or rainfall has caused many environmental problems as declining agricultural productivity, damaging pasture and preventing flow of water. As the interest in environment is increasing lately, soil erosion is considered as a serious problem, whereas the systematic regulation and analysis for that have not established yet. This research shows the method of extracting factor entered model which expects soil erosion by GSIS. There are several erosion model such as ANSWER, WEPP, RUSLE. The research used RUSLE erosion model which could expect general soil erosion connected easily with GSIS data. RUSLE's input factors are composed of rainfall runoff factor(R). soil erodibility factor(K), slope length factor(L), slope steepness factor(S), cover management factor(C) and support practice factor(P). The general equation used to extract L, S factor on the RUSLE to be oriented for agricultural area has some limitation to apply whole watershed. So, on this study we used a revised empirical equation applicable to the watershed by grid on the GSIS. Also, we analyzed RUSLE factors by watershed being analyzed with watershed extraction algorithm. Then we could calculate the minimum, maximum. mean and standard deviation of RUSLE factors by watershed.

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A Fundamental Study of a Neo-Grouting Technology for the Decreasing of a Ground Disaster in a High Water Pressure Conditions (고수압 조건에서의 지반재해 저감을 위한 최신 그라우팅 시공관리 기술 기초연구)

  • Kim, Jin-Chun;Yoo, Byung-Sun;Kang, Hee-Jin;Kwon, Young-Sam
    • Journal of Korean Society of Disaster and Security
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    • v.7 no.1
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    • pp.9-16
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    • 2014
  • In the high water pressure construction conditions, it is important that the failures and damages occurrence in the neighboring ground and impermeable prevention methods (design and construction) for a inflow of seawater into structures. Grouting construction markets include a subway construction, a railway construction, a mountain tunnel construction, a new & reinforced construction of river & reservoir levee with big budget per every years. but, there are economic loss about design and construction management parts because that management criteria is not accurate but depends on experiences. Even though grouting technology are using vitally in the major constructions of national levels, it is still serious about the low-reliability problems and the no-criteria problems. therefor the purpose of this study is that provides the fundamental research about the neo-grouting technology for the decreasing of ground disaster in a high water pressure conditions.

Reliability-Based Managing Criteria for Cable Tension Force in Cable-stayed Bridges (신뢰성에 기초한 사장교 케이블 장력 관리기준치 설정)

  • Cho, Hyo-Nam;Kang, Kyung-Koo;Cha, Cheol-Joon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.9 no.3
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    • pp.129-138
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    • 2005
  • This paper presents a methodology for the determination of optimal managing criteria for cable tension force in cable-stayed bridges using acceleration data acquired by monitoring system. There are many long span bridges installed with monitoring system in Korea. The monitoring systems are installed to diagnose abnormal behavior or damages in bridges and to warn these to bridge management agency. In cable-stayed bridges, the cable tension force could be an important indicator of abnormal behavior because of the geometric configuration of the cable-stayed bridge. If the management value of cable tension force is set too high or too low, then the monitoring system could not warn properly for the abnormal behavior of a bridge. Generally, the management value is set by empirical or engineering judgment, but in this paper, a new methodology for the determination of managing criteria for cable tension force is proposed based on the probability distribution model for tension force and reliability analysis. The proposed methodology is applied to a real concrete cable-stayed bridge in order to investigate its applicability.

Sport Iinjuries by Body Parts in National Judo Athletes: A Retrospective Study (국가대표 유도선수의 신체부위별 스포츠상해에 대한 후향적 연구)

  • Kim, Hye-Young;Chung, Eun-Jung;Lee, Byoung-Hee
    • The Journal of the Korea Contents Association
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    • v.20 no.3
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    • pp.661-670
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    • 2020
  • The purpose of this study was to investigate the incidence of sports injury and trend of incidence pattern of national judo athletes. The research method was analyzed based on the records of all injuries experienced by national judo athletes during training and competition for 9 years from 2008 to 2016. A total of 20,345 sports injuries requiring physical therapy were 10,768 (52.93%) for women, 9,577 (47.07%) for men, lower extremities 9,688 (47.62%), upper limbs 5,807 (28.54%), and trunk 4,850 (23.84%) and knee-related injuries (27.82%) occur more frequently than other injuries. Shoulders, feet and back were more frequent in male athletes, and ankle, neck and hand injuries were more common in female athletes. Using the binomial trend line, the trend of the decrease of sports injuries in each area was shown. However, infrequent injuries such as hands and hips tend to increase gradually. The results of this study are expected to be used as a training program for judo athletes' sports injury and basic data.

Simplified Shock Response Analysis for Submerged Floating Railway against Underwater Explosion (수중폭발에 의한 해중철도의 간이 충격 응답 해석)

  • Seo, Sung-Il;Sa-Gong, Myung;Son, Seung-Wan
    • Journal of the Korean Society for Railway
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    • v.17 no.2
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    • pp.100-105
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    • 2014
  • To design a submerged floating railway that is safe against underwater explosions, railway behavior must be investigated and clarified. In this paper, shock waves and impulse pressures generated by a charge away from the submerged floating railway are expressed using experimental formulas. The submerged floating railway tethered by mooring lines is modeled as a simply supported beam with elastic springs. Finite element analysis for the beam model subjected to impulse loading is conducted so that the response of the submerged floating railway can be investigated. For design purposes, a simplified analysis method combined with dynamic load factor is proposed for the same model. Maximum deformation and internal forces are calculated and compared with the time dependent analysis results. It is shown that the simplified analysis results show good agreement.

Gibbsite 상전이에 관한 전자빔 조사효과의 EF-TEM을 이용한 정량화

  • 김영민;정종만;이수정;김윤중
    • Proceedings of the Korea Crystallographic Association Conference
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    • 2003.05a
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    • pp.11-11
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    • 2003
  • 전자현미경내에서 일부 무기 및 금속 시료들은 전자빔 조사에 의해 시료구조가 손상되거나 비정질화 또는 상전이 등과 같은 구조전이 현상들을 겪게 된다. 즉, 전자빔 조사에 의해 시료는 원자간 결합이 끊어져 나타나는 Knock-on damage, 시료 원자 주위의 전자들과의 상호 작용에 의해 나타나는 Ionization damage, 빔 에너지의 시료온도 상승 기여에 의한 Radiolysis damage 등의 현상들을 경험하게 된다. 이러한 현상은 전자현미경의 가속전압, 전자밀도, 시료 조건 등에 따라 그 지배기구가 다르며 동일한 시편이라도 시료의 두께와 시편온도를 결정하는 전자빔 조사선량에 따라 그 양상과 전이 속도가 달라진다. 본 연구에서는 전자빔 조사에 의해 구조 전이를 겪게 되는 대표적 무기수화물의 하나인 Cibbsite에 대해 전자빔 조사효과에 대한 정량적 고찰을 에너지 여과 투과전자현미경 (EF-TEM)을 이용하여 시도하였다. 전자빔 조사는 120분까지 실시하였고 각 시간별로 에너지 필터와 Imaging plate를 이용하여 Gibbsite의 회절패턴과 미세조직 변화를 기록하였다 빔조사 시엔 illumination angle을 1.25mrad(Dose rate : 334 × 10³ e/sup -//sec·n㎡)으로 하였으며 사진기록 시엔 최소 illumination angle인 0.04mrad(Dose rate : 413 e/sup -//sec·n㎡)을 사용하였다. 시료의 관찰방향은 [001]방향이고 관찰시료두께는 약 50nm로 평가되었으며 시료의 화학변화는 EDS를 이용하여 분석하였다. 회절자료의 Intensity는 ELD/CRISP 프로그램을 이용하였으며 빔조사선량은 평행조사빔이 시료와 상호 작용하는 면적과 상호작용하지 않을 때의 빔을 회절모드에서 faraday cup으로 측정한 빔전류로 부터 계산하였다. Gibbsite에 대한 전자빔 조사 시 1분 이내에 급격한 Hydroxyl Ion(OH-)의 이탈로 인해 Cibbsite의 구조는 거시적 비정질화가 되며 시간증가에 따라 χ-alumina → ν-alumina → σ-alumina or δ-alumina의 순으로 상전이를 겪는다. 전자빔 조사 시 관찰된 회절자료의 가시적 변화를 통해 illumination angle 1.25mrad(Dose rate : 334 × 10³ e/sup -//sec·n㎡)일 경우 약 3초 이내에 비정질화가 시작됨을 알 수 있었고 이는 약 1 × 10/sup 6/ e/sup -//sec·n㎡ 의 전자선량에 해당되며 이를 기준으로 각각의 illumination angle에 대한 임계전자선량을 평가할 수 있었다. 실질적으로 Cibbsite와 같은 무기수화물의 직접가열실험 시 전자빔 조사에 의해 야기되는 상전이 영향을 배제하고 실험을 수행하려면 illumination angle 0.2mrad (Dose rate : 8000 e/sup -//sec·n㎡)이하로 관찰하고 기록되어야 함을 본 자료로부터 알 수 있었다.

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An Empirical Approach for Improving the Estimation of the Concrete Compressive Strength Considered the Effect of Age and Drilled Core Sample (재령과 코어의 영향을 고려한 향상된 콘크리트 압축강도 추정기법의 경험적 제안)

  • Oh, Hongseob;Oh, Kwang-Chin
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.19 no.6
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    • pp.103-111
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    • 2015
  • To evaluate the compressive strength of concrete, rebound test and ultra pulse velocity methods as well as core test were widely used. The predicted strength effected by age, maturity and degradation of concrete, is a slight difference between in-situ concrete strength. The compressive strength of standard cylinder specimens and core samples by obtained from drilling will have a difference since the concrete is disturbed during the drilling by machinery. And the rebound number and ultra pulse velocity are also changed according to the age and maturity of concrete that effected to the surface hardness and microscpic minuteness. The authors performed the experimental work to reflect the age and core effect to the results from NDE test. The test results considering on the core and age of concrete were compaired with the proposed equation to predict the compressive strength.

A Study on the Correlation of Dental Anxiety Based on Dental Fear Scale (DFS) (치과불안척도(DFS)에 근거한 치과공포 연관성 연구)

  • Shin, Jae-Won;Kim, Sun-Il
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.28 no.1
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    • pp.54-60
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    • 2019
  • Objective: Dental fear is a feeling of anxiety and fear without intervention during a dental visit, mainly due to past negative dental treatment experiences, and in adults, despite the recognition of the need for dental treatment, it can lead to avoidance of dental treatment, which may cause deterioration of oral health. Therefore, this study was conducted to measure dental fear and anxiety level in some adults, and to identify related factors and their causes. Methods: This study used Kleinknecht's Dental Fear Survey scale and the SPSS 21 program (IBM SPSS Statistics 21) was used for analysis. Result: When the dental fear was the higher, the "access to the dental clinic" was found to be the highest, followed by "sitting in dental unit chair" and "smell of dental clinic" in that order. Conclusions: Dentists and dental hygienists should be able to understand the fear, anxiety, and concerns of the dentist office and to find various ways to provide systematic medical services.

Treatment of Glomus Tumor (사구종양의 치료)

  • Song, Seok-Whan;Woo, Young-Kyun;Rhee, Seung-Koo;Lee, Hwa-Sung;Lee, Sang-Hoon
    • The Journal of the Korean bone and joint tumor society
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    • v.3 no.2
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    • pp.105-111
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    • 1997
  • From 1988 to 1997, we experienced 11 cases of glomus tumor in fingers(10 cases) and toe(1 case). All patients were female, and showed typical pain, tenderness, and cold sensitivity of the lesions. The locations were subungal in nine cases and in pulp from distal phalangeal bone in two cases. Three patients had histories of one or two failed previous operations, and two patients had another glomus tumor in their bodies. All except one had satisfactory results subjectively and without complications. One patient was operated by the excision of the tumor including germinal matrix and surrounding tissues of nail bed, and had a nail deformity in follow-up. The glomus tumor is not malignant to recur or metastasize in the case of complete excision. However, the surgeon should be alert not to injure or repair the nail bed meticulously after the excision of the tumor to prevent a late deformity of nail.

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