• Korean Journal of Environmental Biology
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• v.29 no.3
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• pp.236-240
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• 2011

Mercury known as quicksilver, is the most common cause of heavy metal toxicity. Toxicity caused by excessive mercury exposure is now being recognized as a widespread environmental problem and is continuing to attract a great deal of public concerns. The mercury genotoxicity could be its effect on DNA repair mechanisms, which constitute the defense system designated to protect genome integrity. The objective of this study is to confirm that mercuric chloride inhibits the repair of gamma ray-induced DNA damage. The earthworm of Eisenia fetida was chosen for this study because it is an internationally accepted model species for toxicity testing with a cosmopolitan distribution. Experiments were done to identify the levels of DNA damage and the repair kinetics in the coelomocytes of E. fetida irradiated with 20 Gy gamma rays alone or with gamma rays after 40 mg $kg^{-1}$ $HgCl_2$ treatment by means of the single cell gel electrophoresis assay. The Olive tail moments were measured during 0~96 hours after irradiation. The repair time in the animals treated with the combination of $HgCl_2$ and ionizing radiation was nearly five times longer than that in the animals treated with ionizing radiation alone. Also, E. fetida exposed to mercury showed a statistically lower repair efficiency of gamma ray-induced DNA damage. The results suggest that the mercury could even have deleterious effects on the DNA repair system. Influence of mercury on the DNA repair mechanisms has been confirmed by this study.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2017.04a
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• pp.58-58
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• 2017

점적 호스의 원통형 미로 구조물내의 유동특성을 분석하기 위해 금속판에 동일한 구조의 미로가 가공된 시험부를 활용하여 압력과 유량의 변화에 대한 실험을 CFD 해석하였다. 해석은 미로의 길이에 따른 유량 특성을 정밀하게 분석하기 위해 전체 미로에 구간별 총 8개의 배출구를 배치하고 밸브 조절을 통해 구간별 압력에 따른 유량을 측정함으로서 실험에 의한 압력과 유량의 관계를 검증하고 새로운 경질 미로를 설계하는데 응용하고자 한다. 경질 미로의 이론적인 해석에서 정밀도가 실험을 대신할 가능성이 있는지에 관심을 두었다. 점적관수의 경질 미로는 디자인을 달리함으로써 성능이 높고 미세한 스케일이 침착되지 않는 고성능의 점적관수 장치의 개발이 가능할 것으로 판단하였다. 미로 입구의 공급 유체 압력(Gauge pressure)을 0.5, 1.5, 2.5, 3.0 bar로 나누어 공급하였으며, 8개의 구간별 유출되는 유량은 전자저울에서 측정하였다. 향후 최적 미로의 새로운 설계를 위해 미로구조 전체를 CFD 해석하였고 그 결과를 실험치와 비교 분석하였다. 또한 경질 미로내 각 구간별 세부적인 유동구조를 분석하였고 해석결과와 실험결과를 통해 향후 새로운 경질 구조의 개발이 가능 할 것으로 판단되었다. 경질 미로의 입구압력에 따른 미로의 길이 #1과 #2에 대한 CFD 분석에서는 전체적으로 경질 미로에 압력이 증가할수록 미로의 유체 속도가 증가됨을 알 수 있었으며 이것은 #2에서도 거의 같은 양상을 나타내었다. 미로 통로에서는 와류로 인한 이물질의 멈춤 현상이 발생하지 않을 만큼 흐름이 원활함을 알 수 있었다. 미로의 길이 #3과 #4에 대한 CFD 분석과 미로의 길이 #5와 #6에 대한 CFD 분석에서는 압력이 증가하고 미로의 길이가 길어질수록 속도에도 영향을 미치고 있는 것으로 나타났으며 미로와 미로 사이의 넒은 통로에서는 유속이 크게 떨어지고 있음을 알 수 있었다. 따라서 이 부분에는 유체속의 이물질이 침착할 수 있는 가능성이 있으며 통로가 좁은 곳에서는 유속이 증가되는 것으로 나타났다. #7과 #8은 미로의 상하단으로 유출되는 부분의 차이이므로 실질적으로 해석의 결과는 차이가 없었다. 경질 미로에 대한 압력에 따른 미로의 길이별 유출량은 지수적인 반비례 현상을 나타내어 앞서 실험한 연구의 결과와 1~2% 오차 범위에서 잘 일치하였다. 따라서 점적 호스의 경질 미로에 대한 설계는 이론적인 해석을 통하여 새로운 디자인이 가능할 것으로 판단되었다. 경질 미로의 미로의 길이에 따른 CFD 분석의 결과는 실험적인 유출량의 값과 거의 일치하였다. 미로와 미로 사이의 넒은 통로에서는 유속이 크게 떨어져 이물질들이 침착될 가능성이 있었으며 실질적으로 넓게 설계하는 것이 유리하지 않을 것으로 판단되었다. 경질 미로에 대한 압력에 따른 미로의 길이별 유출량은 지수적으로 반비례 하였으며 점적 호스의 경질 미로에 대한 새로운 설계는 이론적인 해석을 통하여 가능할 것으로 판단되었다.

• The korean journal of orthodontics
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• v.35 no.3 s.110
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• pp.196-206
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• 2005

This study was undertaken to investigate the effect of vitamin C deficiency on the orthodontic tooth movement and bony remodeling processes. Thirty six male guinea pigs were divided on the basis of the given amount of vitamin C (normal group: 5mg/day, deficient group: 0.2mg/day) and 75gm of force was applied to the maxillary incisors. Experimental animals were sacrificed at day 0. day 1 day 3, day 5. day 7 and day 14 after force application and the amount of tooth movement was measured and tissues were studied histologically. The results showed that the amount of collagen fiber in the periodontal ligament and alveolar bone of the deficient group was less than that of the normal group. In the stretched side. the osteoblastic activity and alveolar bone formation of the normal group increased in a time dependent manner during experimental periods, but the deficient group showed less activity and formation. The amount of tooth movement in the deficiency group was more than in the normal group at day 0. day 1, day 3, day 5, and day 7. According to the above results, a deficiency of vitamin C resulted in a defect of collagen synthesis of the periodontium and inhibition of bone formation and stimulation of bone resorption with rapid tooth movement in early periods of force application.

• Economic and Environmental Geology
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• v.45 no.5
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• pp.503-512
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• 2012

We performed DInSAR (Differential Interferometric SAR) and SBAS (Small BAseline Subset) analysis using spaceborne SAR (Synthetic Aperture Radar) in order to detect a surface subsidence in Taebaek area, Kangwon, which are suitable to the monitoring of broad and inaccessible areas. During the period from October 2006 to June 2010, we acquired twenty-three ALOS PALSAR data sets (path/frame=425/730) for this study. The ninety-six differential interferograms with a perpendicular baseline less than 1100 m were constructed by ROI_PAC, then the mean velocity map of surface displacement was derived from SBAS analysis. As a result, it was confirmed that the ground displacement occurred about 4 cm/yr at Seokgong-Jangseong and Kyungdong mines and 2 cm/yr at Saehan-Eoryong-Jungdong and Hwangji mines in Taebaek area, Kangwon. It seems that the subsidence in study area is closely related to mining activities because the most of subsiding areas are well matched with mining areas. The subsidence at Kyungdong mine shows continuous and fast velocity in about $2{\times}2$ km area. Therefore the further analysis and the effort to prevent disaster are required in this area.

• Journal of Life Science
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• v.26 no.11
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• pp.1253-1258
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• 2016

Although major advances have been achieved in our understanding and treatment of diseases in many areas of medicine, relatively few improvements have been made in the area of gastrointestinal (GI) motor function. The dried root of Codonopsis pilosula (Franch.) Nannf. (CP) has been used as a traditional folk medicine for improving poor GI function in East Asia, including China and Korea. In the present study, neither aqueous (CP-W) nor ethanolic (CP-E) extracts of CP showed significant toxicity, even at an oral dose of 5 g/kg to mice. The effects of CP-W and CP-E on GI motor function were investigated by measuring in vivo the gastric emptying rate (GER) and intestinal transit rate (ITR) in mice. In normal mice, the ITR was significantly increased by CP-W in a dose-dependent manner, whereas the GER was not significantly affected by any CP extracts. The ITR was significantly retarded in the mice with experimental GI motility dysfunction (i.e., peritoneal irritation by acetic acid) compared with that in normal mice. However, the retardation was significantly recovered by the pre-treatment of CP-W in a dose-dependent manner. The above results suggest that CP-W might be a potential prokinetic agent preventing or alleviating GI motility dysfunctions in human patients.

• Geophysics and Geophysical Exploration
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• v.13 no.3
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• pp.256-267
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• 2010

Earthquakes in the Korean Peninsula occur along the faults formed and boundaries between major geological units ruptured due to violent tectonic activities during the Mesozoic. E-W and/or ENE-SSW compressive stress regime resulting from collisions between the Eurasian plate and neighbouring the Indian plate, the Pacific plate and the Philippine plate trigger Korean earthquakes of thrust faulting with predominant strike-slip components along the mostly NNE-SSW trending active faults. Seismicity of the Korean peninsula has been moderate to low during the past 20 centuries except for the period from the 15th to the 18th centuries of exceptionally high seismicity, showing the typical irregularity of intraplate seismicity. The structure of the Korean peninsula is rather homogeneous without the Conrad discontinuity sharply dividing the upper and lower crust. Lateral heterogeneities exist in the crust. The crust with an average thickness of about 33 km is thicker in the mountainous region than the plain due to the Airy-type isostatic equilibrium maintained in the peninsula. Crustal P-wave velocity with average of about 6.3 km/sec increases gradually from the near surface to the Moho. The upper mantle P-wave (Pn) velocity is about 7.8 km/sec.

• Journal of the Mineralogical Society of Korea
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• v.7 no.1
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• pp.40-48
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• 1994

The weathering of the Namsan granite was studied in terms of sorption process. The Namsan granite consists mainly of quartz, alkali feldspar, plagioclase (${Ab_{85}An_{15}}-Ab_{100}$ and biotite with small amounts of sericite, magnetite and ilmenite. The kinetic factors for altering the granite body are the proton and hydroxyl ions derived from the reaction of water and mineral. There are two different types of pH variation curves for rocks of different mineral assemblages. when powdered granite was dispersed in distilled water under ambient condition. The sorption-process proceeds by three steps for fresh granite; (1) the initial rapid pH-rise to 10 by the uptake of proton by negatively charged mineral surfaces, (2) the gradual pH-down, and (3) the stable pH tail between 7.1-7.5. For somewhat weathered granites, the sorption proceeds; (1) the initial rapid pH-down to 4.8, (2) the slight pH-rise and slow ph-down, and (3) the stable pH tail between 5.0-5.3. The reaction rate is controlled by the density of adsorbable sites, the solubility of the mineral, pH of the system and formation of amorphous gel and gibbsite. Amorphous gel floates on the surface of the solution while stirring the powdered granite and then is transformed into gibbsite in an hour or so. The pH saturation values for -325 mesh fresh granite from 5 m depth is about pH 10 when rock/water ratio is over 10g/200 ml.

• The Journal of Engineering Geology
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• v.17 no.1 s.50
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• pp.57-64
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• 2007

This study was conducted to characterize on the relationships among rainfall intensity, slope angle and pore water pressure in the gneissic weathered soil by landslide laboratory flume tests. Under the several test conditions dependent on rainfall intensity and slope angle, the authors measured pore water pressure, failure and displacement of slope on a regular time interval. According to the test results, the increasing times of pore water pressures have direct proportional trends to the rainfall intensity. The pore water pressure was increased earlier at the head part of slope than the toe part. Compared with the test results of Chae et al(2006), the results of this study explain that the seepage velocity in the gneissic weathered soil is slower than that in the standard sands. It results in faster and ear-lier increase of pore water pressure at the head part of slope due to slow flow of water in the gneissic weathered soil. In case of the relationship between slope angle and pore water pressure, gentle slope angle has faster increase of pore water pressure than steeper slope angle. It is also thought to be due to slow seepage velocity and flow velocity in the gneissic weathered soil.

• Journal of the Korean Society of Food Culture
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• v.3 no.3
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• pp.309-317
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• 1988

The effects of $CaCl_2$, K-sorbate, and fermented fish sauces and blanching on the texture of Chinese cabbage of Kimchi were evaluated. The addition of salt-fermented shrimp or salt-fermented anchovy accelerated the pH reduction, acidity increase and reducing sugar consumption, but K-sorbate, Ca-chloride and blanching suppressed the ripening process of Kimchi. The latter retarded the softening rate of Chinese cabbage during Kimchi fermentation, as demonstrated by the cutting force, compression force, recovered height and work ratio. The sensory evaluation confirmed the results of instrumental texture measurments. The instrumental measurements, i.e. pH, acidity cutting thickness, cutting force and compression test parameters, showed acidity acidity was calculated as % lactic acid attributes, i.e. the preferences for taste, appearance and texture, and the level of crispiness, hardness, chewiness and fibrousness. The pH of Kimchi was appeared to be an important quality parameter, whiih had significant correlations with the taste, appearance, chewiness, hardness, fibrousness and crispiness.

• Journal of Food Hygiene and Safety
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• v.14 no.4
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• pp.339-345
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• 1999

The present study was performed to investigate photodegradation rate constants and degradation products of dichlorvos and methidathion by the USEPA method. The two pesticides were very stable in sunlight for 16 days from September 2 to 18, 1998 and humic acid had no sensitizing effect on the photolysis of each pesticide in sunlight. The photolysis rate was fast-est for methidathion, followed by dichlorvos in the presence of UV irradiation. Photodegradation rate constant and half-life of dichlorvos were 0.0208 and 33.3 min, respectively. Photodegradation rate constant and half-life of methidathion were 0.6789 and 1.0min, respectively. The two pesticides were degraded completely in the presence of UV irradiation and UV irradiation with TiO$_2$in about 3 hours. Therefore, it is suggested that UV treatment will be effective for the degradation of pesticides in the process of drinking water purification. In case of dichlorvos and methidathion, UV irradiation with TiO$_2$was more effective for degradation than W irradiation. In order to identify photolysis products, the extracts of degradation products were analyzed by GC/ MS. The mass spectrum of photolysis products of dichlorvos was at m/z 153, those of the photolysis of methidathion were at m/z 198 and 214, respectively. Photolysis products of dichlorvos was Ο, Ο-dimethyl phosphate(DMP), those of methidathion were Ο, Ο-dimethyl phosphorothioate(DMTP) and Ο, Ο-dimethyl phosphorodithioate (DMDTP).