• Title/Summary/Keyword: 소인경

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Pulmonary Resection Combined with Isoniazid-and Rifampin-based Drug Therapy for Patients with Multidrug-resistant Tuberculosis (다제내성 폐결핵 환자에서 폐절제술 후 일차 항결핵제 치료)

  • Park, Seung-Kyu;Kim, Jin-Hee;Kim, Jun-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.2
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    • pp.179-185
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    • 2005
  • Background : To evaluate the clinical efficacy of pulmonary resection combined with first-line antituberculous drug therapy in patients with well-localized, cavities-containing pulmonary multidrug-resistant tuberculosis (MDR-TB). Method : From February 1998, seventeen patients with well-localized, cavities-containing pulmonary MDR-TB were enrolled and followed prospectively up to December 2004. After radical pulmonary resection, the patients were treated with antituberculous drugs comprising of isoniazid (H), rifampin (R), pyrazinamide (Z), ethambutol (E), and streptomycin (S) (3HERZS/3HERS/6HER). Results : All recovered isolates of M. tuberculosis were resistant to both isoniazid and rifampin, and to a mean of 4.8 antituberculous drugs (range, 2 to 7 drugs). Surgical procedures included lobectomy (13 patients), lobectomy plus segmentectomy (3 patients), and pneumonectomy (1 patient). The median time for postoperative sputum smear and culture conversion was 2 days (range, 1 to 23 days). Fifteen (94%) patients had durable cures (mean follow-up period, 39.0 months). One patient failed to convert her sputum and was successfully switched to second-line therapy; one patient developed active disease again almost 7 years later, likely due to re-infection with a new M. tuberculosis strain. Conclusion : Radical resection combined with administration of first-line antituberculous agents was effective in patients with well-localized, cavities-containing pulmonary MDR-TB.

Analysis of Q Values on the Crust of the Kimcheon and Mokpo Regions, South Korea (남한 김천.목포 일대 지각의 Q 값 분석)

  • Do, Ji-Young;Lee, Yoon-Joong;Kyung, Jai-Bok
    • Journal of the Korean earth science society
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    • v.27 no.4
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    • pp.475-485
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    • 2006
  • The physical properties of the central and southwestern crust of South Korea were estimated by comparing values of ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ in the Kimcheon and Mokpo areas. In order to get ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ values, seismic data were collected from two stations of the KIGAM network (KMC and MUN) and four stations of the KMA network (CPN, KUC, MOP, and WAN). An extended coda-normalization method was applied to these data. Estimates of ${Q_P}^{-1}\;and\;{Q_S}^{-1}$ show variations depending on frequency. As frequencies vary from 3 Hz to 24 Hz, the estimates decrease from $(1.4{\pm}3.9){\times}10^{-3}\;to\;(2.3{\pm}3.5){\times}10^{-4}\;for\;{Q_P}^{-1}\;and\;(1.8{\pm}1.3){\times}10^{-3}\;to\;(1.9{\pm}1.5){\times}10^{-4}\;for\;{Q_S}^{-1}$ in central South Korea, and $(5.9{\pm}4.8){\times}10^{-3}\;to\;(2.2{\pm}3.8){\times}10^{-4}\;for\;{Q_P}^{-1}\;and\;(0.5{\pm}2.8){\times}10^{-3}\;to\;(1.8{\pm}1.6){\times}10^{-4}\;for\;{Q_S}^{-1}$ in southwestern South Korea. According that a frequency-dependent power law is applied to the data, the best fits of ${Q_P}^{-1}\;and\;{Q_S}^{-1}\;are\;0.003f^{-0.49}\;and\;0.005f^{-1.03}$ in central South Korea, and $0.026f^{-1.47}$ and $0.001f^{-0.49}$ in southwestern South Korea, respectively. These values almost correspond to those of seismically stable regions although ${Q_P}^{-1}$ values of southwestern South Korea are a little high due to lack of data used.

Superior Labral Dimension of the Glenohumeral Joint on Direct MR Arthrography (MRA): Relationship with Presence of SLAP (Superior Labrum Anterior to Posterior) Lesion (직접 자기공명 견관절 조영술 상에서 상부 관절순의 크기: 상부 관절순 전후방 파열과의 관계)

  • Im, Tae Seong;Choi, Jung-Ah;Oh, Joo Han
    • Investigative Magnetic Resonance Imaging
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    • v.18 no.3
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    • pp.193-199
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    • 2014
  • Purpose : To evaluate the relationship between superior labral dimension of the glenohumeral joint on direct MRA and presence of SLAP lesion. Materials and Methods: IRB approval was obtained and informed consent was waived for this retrospective study. Direct MRA studies of the shoulder in 296 patients (300 shoulders) with arthroscopic surgery were analyzed by two radiologists blinded to the arthroscopic results, which were used as gold standard. One of the radiologists reviewed the images twice (session 1 and 2) for the evaluation of intra-observer variability. Transverse and longitudinal dimensions of superior labrum on coronal T1-weighted images were measured as base and height of the inverted triangular-shaped superior labrum and compared between patients with SLAP lesions vs. non-SLAP patients. Presence of meniscoid labrum was noted. Statistical analysis was done using unpaired t-test. Results: Among 279 patients (283 shoulders), 122 patients (43.1%) had SLAP lesions. The mean base/height of superior labrum in SLAP and non-SLAP patients measured on T1-weighted MR image were 8.8 mm / 5.2 mm, 8.5 mm / 4.9 mm for reader 1; 8.2 mm / 4.9 mm, 8.1 mm / 4.5 mm for session 1 of reader 2; 8.0 mm / 4.8 mm, 7.6 mm / 4.3 mm for session 2 of reader 2. In SLAP group, the mean labral height was larger than non-SLAP group with statistically significant difference (p<0.05). Fifteen patients (5.3%) had meniscoid labrum according to operation records. Conclusion: In patients with SLAP lesion, the height of the superior glenoid labrum on oblique coronal image of MRA was slightly larger than non-SLAP patients. A larger height of superior glenoid labrum may be associated with SLAP lesions.

A Correlational Study among Internal Marketing Factor, Nurse's Job Satisfaction, and Organizational Commitment in Hospital Nursing Organization (병원간호조직의 내부마케팅요인과 간호사의 직무만족, 조직몰입과의 관계연구)

  • Kim So In;Cha Sun Kyung;Lim Ji Young
    • Journal of Korean Public Health Nursing
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    • v.15 no.1
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    • pp.42-55
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    • 2001
  • The purpose of this study was to provide basic information for developing effective marketing strategies of nursing organization by identifying the correlation among internal marketing factor, nurses' job satisfaction, and organizational commitment. The subjects of this study were 256 nurses who were working in the hospital over 1 year at three university hospitals which had more than 400 beds in seoul and kyung-gido. The data were collected by self-reporting questionnaires. The instruments used in this study were the communication form scale developed by Jo(1995), the welfare scale developed by researcher, the education training scale developed by researcher, the organizational commitment scale developed by Mowday, Porter and Steers(1979). The data were analysed by the SAS package using frequency, percentage, mean, standard deviation, and Pearson's correlation coefficient. The results of this study were as follows; 1. Mean scores of internal marketing factors in nursing organization were as follows; horizontal communication 3.42, downward communication 3.32, involvement communication 3.08, upward communication 3.00, education training 2.54, welfare 2.51. The mean score of job satisfaction was 2.79 and organizational commitment was 3.00. 2. Job satisfaction was positively correlated with education training (r=0.54, p=0.0001), upward communication(r=0.49, p=0.0001). welfare (r=0.40, p=0.0001), horizontal communication(r=0.33, p=0.0001), involvement communication(r=0.25, p=0.0001) of internal marketing factors in nursing organization, but negatively correlated with downward communication(r=-0.16. p=0.0082). Organizational commitment was positively correlated with upward communication(r=0.48, p=0.0001), education training (r=0.42, p=0.0001), horizontal communication(r=0.36, p=0.0001), welfare (r=0.34, p=0.0001), involvement communication(r=0.25, p=0.0001) of internal marketing factors in nursing organization. but negatively correlated with downward communication(r=-0.20, p=0.0014). In conclusion. the results of this study showed that the internal marketing factors were highly correlated with nurses' job satisfaction and organizational commitment. Therefore, for nurses' job satisfaction and organizational commitment's improvement, it is important to develop the education training program. to improve welfare system and to actualize upward communication. among internal marketing factors.

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Quality Characteristics of Muffins containing Beet Powder (비트 가루 첨가량에 따른 머핀의 품질특성)

  • Seo, Eun-Ok;Ko, Seng-Hye
    • Culinary science and hospitality research
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    • v.20 no.1
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    • pp.27-37
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    • 2014
  • This study examines the quality characteristics of the muffins made by adding 3%, 6%, and 9% of beet powder, comparing with the reference group. The result showed that there has been no significant difference in the ash content from the groups added with 3% and 9% of beet powder. The height of muffins appeared to be 4.7~5.0 cm, which didn't show any significant difference among the samples. The volume of beet muffins has shown significant difference among the samples (p<0.001). From the measurement result by scanning electron microscope (SEM), the samples had thick cellular walls and coarse pores because there was less gluten content with increased beet powder. From the chromaticity measurement result, L value and b-value decreased, while a-value increased with increased beet powder. From the texture measurement result, hardness increased with increased beet powder. Adhesiveness appeared to be getting lower with increased beet powder. Also, there was significant difference among the samples for cohesiveness (p<0.001). Gumminess got higher in the samples added with 3% and 6% of beet powder, and the highest chewiness was shown in the sample group added with 3% of beet powder. From the sensory evaluation result, overall acceptance has appeared in order of 6% > 9% > 3% > 0%.

The Understanding of Depression Subtypes (우울증 아형들의 이해)

  • Han, Chang-Hwan;Ryu, Seong Gon
    • Korean Journal of Biological Psychiatry
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    • v.8 no.1
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    • pp.20-36
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    • 2001
  • The debate about whether depressive disorders should be divided into categories or arrayed along a continuum has gone for decade, without resolution. In our review, there is more evidence consistent with the spectrum concept than there is with the idea that depressive disorders constitute discrete clusters marked by relatively discontinuous boundaries. First, "depression spectrum", "is there a common genetic factors in bipolar and unipolar affective disorder", "threshold model of depression" and "bipolar spectrum disorder" are reviewed. And, a new subtype of depression is so called SeCA depression that is a stressor-precipitated, cortisol-induced, serotonin-related, anxiety/aggression-driven depression. SeCA depression is discussed. But, there is with the idea that depressive disorders constitute discrete subtypes marked by relatively discontinuous boundaries. This subtypes of depressive disorder were reviewed from a variety of theoretical frames of reference. The following issues are discussed ; Dexamethasone suppression test(DST), TRH stimulation test, MHPG, Temperament Character Inventory(TCI), and heart rate variability(HRV).

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Neuroendocrine Study of the Korean Native Cattle: Pulsatile LHRH Release from Hypothalamic Tissues Superfused in vitor (한우의 신경내분비학적 연구 : 시상하부의 체외배양 조직에서 맥동적 LHRH분비 양상에 관하여)

  • 김경진;유선경;안혜영;이병주;강해묵;조완규
    • The Korean Journal of Zoology
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    • v.32 no.3
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    • pp.275-280
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    • 1989
  • Present study examined the endogenous release of luteinizing hormone releasing hormone (LHRH) from superiused hypothalamic sBces derived from Korean native cattie (KNC). In addition, the in vitro secretory pattern of LHRH release in '(NC was compared with that in imported cattle such as Holstein cow. The median eminences (ME) of hypothalamic tissues were disseded out, sliced and quici'ly placed in ice-cold superfilsion chamber. Superhision chambers containing ME slices were maintained in a constant temperature water-bath at 37$^{\circ}C$. Effluents were colleded on ice at 10 min intervals for a 4 hr superfusion period, and kept -2$0^{\circ}C$ prior to LHRH radloimmunoassay. LHRH release was analyzed by the PULSAR algorithm. The spontaneous release of LHRH from both cows was episodic during a 4 hr superhision period. The mean LHRH release, pulse amplitude and pulse interval m KNC were 11.08 $\pm$ 1.50 pg/min/mg x 10-$^2$, 21.43 1 7.28 pg/mg x 10-$^2$, and 39.42 $\pm$ 3.08 min, which were quite similar to those observed in Holstein cows. The basic charaderistics of the LHRH pulse generator of '(NC appears important for a better understanding about the endocrine function of KNC.

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A Study of Broadband Propagation Characteristics for The Future Mobile Communications (II) - The Improvement of Broadband Propagation Characteristics using Polarization Diversity under Indoor Environment (차세대 이동통신에서의 광대역 전파특성 연구(II) - 편파 다이버시티를 이용한 실내에서의 광대역 전파특성 개선-)

  • 하덕호;윤영석
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.10 no.1
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    • pp.78-89
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    • 1999
  • In this paper, to improve bandwidth amplitude fluctuation for the broadband signal in indoor propagation environment, we measured and analyzed broadband signal using a vertically polarized, horizontally polarized and circularly polarized antenna, conducting by frequency sweeping method in NLOS (Non-Line-of-Sight) environment. And, to investigate the optimum condition for the improvement of broadband propagation characteristics we also examined the effects of both human motions and transmission antenna height in the NLOS environment. As a result, in the case of NLOS environment, it was found that the amplitude deviation characteristics in frequency bandwidth can be improved by polarization diversity reception. Especially, we found that it is the best effective one to make polarization diversity reception branches, which install the circularly polarized antenna at transmitting end and install the polarized diversity branches received vertical or/and horizontal polarized wave at receiving end. The affection of a human motions is not so much in LOS and NLOS environment, but it can lead to the cause of burst error in indoor digital radio communications as the fade of signal strength become more deeper. And also, when raise the transmitting antenna up to the ceiling, the LOS and NLOS environment could be coexisted. In this case, it can be also inferred that frequency bandwidth amplitude deviation must be fundamentally improved by using polarization diversity reception technique to make the possibility of high transmission rate.

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Identification of Regenerable Cells in MesophyII Protoplast Cultures (엽조직에서 나출된 원형질체의 재생 가능 세포판별)

  • 소인섭;유장걸
    • Korean Journal of Plant Tissue Culture
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    • v.21 no.1
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    • pp.23-28
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    • 1994
  • This study was rimed out to examine the difference in the cell vitality between mesophyII protoplast (MP) and paraveinal mesophyII protoplast (PVMP) of Nicotiana tabaccum 'Xanti', Petunia hybrida 'Blue Star' and Chrysanthemum morifolium 'Baeckwang' by using urea permeability technique. The effects of various enzyme solutions and incubation time, NAA and thidiazron on plant regeneration from isolated protoplasts were also investigated. The vibratome technique was used for protoplast isolation and urea permeability test because the fresh living, thin tissue stripes (50 ${\mu}{\textrm}{m}$ of thickness) could be obtained with minimal damage with the vibratome. For the three plants examined, the urea permeability on the tested tissue stripes was relatively higher in PVMP than in MP by about Ks = 2.0 $\times$ 10$^{-5}$ cm/sec. The treatment of an enzyme mixture of 1.5% cellulase R-10, 1% Driselase, 0.5% Macerozyme R-10, and 0.5% Pectinase for 4 to 8 h was effective on the isolation of PVMP. The highest frequency of callus formation and plant regeneration from the isolated protoplasts was obtained with NAA 2 mg/L and thidiazuron 0.01 mg/L. Furthermore, the results demonstrated that cell devision and plantlet regeneration was more frequent in the PVMP than in the MP of the same leaf or plant We, therefore, conclude that UM is an excellent experimental material for the callus formation and regeneration from isolated protoplasts.

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Studies on the growth and properties of orthophosphate crystals by the hydrothermal method (수열법에 의한 올소인산염 결정의 육성과 성질에 관한 연구)

  • Pan-Chae Kim
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.4 no.2
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    • pp.139-147
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    • 1994
  • Orthophosphate crystals were grown by the hydrothermal method and the properties of grown crystals were investigated by means of X-ray diffraction. Vickers hardness tester, etc. The starting powders of $AIPO_4 and GaPO_4 $were prepared as a single phase by the solid state reaction of stoichiometric mixture of $AI_2O_3 or Ga_2O_3$ and $NH_4H_2PO_4$ and the subsequently by the hydrothermal treatment. The hydrothermal conditions for high growth rates of the orthophosphate crystals are as follows: $AlPO_4$ crystal; temperature ranges, between $170$~$200^{\circ}C$; temperatures difference, $15$~$20^{\circ}C;$, hydrothermal solvent, 4m HCl, $GaPO_4 crystal; temperature ranges, between $210 and 240^{\circ}C;$; temperature difference, $25$~$30^{\circ}C; $, hydrothermal solvent, 4m HCl. Morphologies of grown crystals tended to be bounded by (1010), (1011) and (0111) faces at low temperatures, and grew with well developed (0001) faces by increasing the growth temperature. On the other hand, the properties of orthophosphate crystals $(AlPO_4/GaPO_4)$ were as follows: lattice parameters (nm); a=0.494, c=1.094/a=0.490, c=1.105, density (gcm-3); 2.62/3.56, Vickers hardness (Nm^2); $1.02{\times}10^1^0/7.06{\times}10^9$, refractive indices; $ne=1.529{\pm}0.003, no=1.519{\pm}0.003/ne=1.611{\pm}0.006, no=1.599{\pm}0.006, birefringence; {\pm}0.01/{\pm}0.012$, dielectric constant (Fm-1); 6/7.

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