• Title/Summary/Keyword: 세균성

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Predictors of Clinically Non Specific Bacterial Infection in Febrile Children Less than 3 Years of Age : WBC, ESR and CRP (비특이적 소견을 보이는 3세 이하의 발열 환아에서 세균성 감염의 예측 인자 : 백혈구 수, 적혈구 침강 속도, C-반응성 단백질)

  • Nho, Jeong A;Rho, Young Il;Yang, Eun Seuk;Kim, Eun Young;Park, Yeong Bong;Moon, Kyung Rye
    • Clinical and Experimental Pediatrics
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    • v.46 no.8
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    • pp.758-762
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    • 2003
  • Purpose : Our examination was designed to determine the diagnostic properties of the cutoff point for the prediction of bacteremia in febrile children less than 3 years of age. Cutoff point is the value that simultaneously maximizes both sensitivity and specificity. Methods : We conducted a retrospective study of febrile children, less than 3 years of age, who clinically have no identifiable source of fever. Peripheral blood leukocyte count(WBC), absolute neutrophil count(ANC), erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) were measured at the same time. All patients received blood culture, urine culture and/or CSF culture. Bacterial infection was defined as single pathogen isolated from the CSF or blood or a urinary tract infection (UTI). Patients were dichotomized into two groups : those with bacterial infection and no bacterial infection. We analyzed the characteristics of the children in the two groups. Results : Seventy-one patients(44 males; 27 females) were enrolled in the study. Twenty patients (28%) had a serious bacterial infection(twelve urinary tract infection, five bacteremia, three meningitis) and fifty-one(72%) had no serious bacterial infection. WBC, ESR and CRP were significantly different between the two groups(P<0.05). The cutoff point of WBC, ESR and CRP were $20,000/mm^3$, 30 mm/hr and 3.0 mg/dL, respectively. The sensitivity and specificity of each cutoff point were WBC(75%, 75%), ESR(79%, 68%) and CRP(83%, 77%), respectively. Conclusion : These data show the ability of predictors to identify febrile children less than 3 years of age with bacterial infection. Febrile children who reach the cutoff point must be treated intensively and those who do not reach the cutoff point can be carefully managed without administering antimicrobial agents.

New Approaches to the Control of Pathogenic Oral Bacteria (바이오필름을 생성하는 병원성 구강 세균을 제어하는 새로운 접근법)

  • Cho, Soo Jeong
    • Journal of Life Science
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    • v.31 no.1
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    • pp.100-108
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    • 2021
  • In the oral cavity, there are hundreds of microbial species that exist as planktonic cells or are incorporated into biofilms. The accumulation and proliferation of pathogenic bacteria in the oral biofilm can lead to caries and periodontitis, which are typical oral diseases. The oral bacteria in the biofilm not only can resist environmental stress inside the oral cavity, but also have a 1,000 times higher resistance to antibiotics than planktonic cells by genes exchange through the interaction between cells in the oral biofilm. Therefore, if the formation of oral biofilm is suppressed or removed, oral diseases caused by bacterial infection can be more effectively prevented or treated. In particular, since oral biofilms have the characteristic of forming a biofilm by gathering several bacteria, quorum sensing, a signaling system between cells, can be a target for controlling the oral biofilm. In addition, a method of inhibiting biofilm formation by using arginine, an alkali-producing substrate of oral bacteria, is used to convert the distribution of oral microorganisms into an environment similar to that of healthy teeth or inhibit the secretion of glucosyltransferase by S. mutans to inhibit the formation of non-soluble glucans. It can be a target to control oral biofilm. This method of inhibiting or removing the oral biofilm formation rather than inducing the death of pathogenic bacteria in the oral cavity will be a new strategy that can selectively prevent or therapeutic avenues for oral diseases including dental caries.

Non-surgical Treatment for Secondary Spontaneous Pneumothorax Associated with Bacterial Pneumonia in a Beagle Dog (비글견에서 세균성 폐렴으로 인한 속발성 자발 기흉의 비외과적 치료)

  • Han, Hyun-Jung;Yoon, Hun-Young;Kim, Jun-Young;Jang, Ha-Young;Choi, Seok-Hwa;Jeong, Soon-Wuk
    • Journal of Veterinary Clinics
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    • v.25 no.1
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    • pp.31-36
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    • 2008
  • One year old, male beagle dog was presented with acute onset of severe dyspnea, cyanosis, and anorexia. He had no trauma history. Five days earlier, the dog had been diagnosed as bacterial pneumonia caused by Pseudomonas aeruginora and E. coli. He exhibited a restrictive respiratory pattern and at admission, immediately oxygen supplementation given. On a ventrodorsal(VD) radiographic view, right lung was collapsed and contrasted with the air-filled pleural space. The mediastinum, heart, and great vessels were shifted to the left. On a right-lateral radioraphic view, the heart appeared to be elevated from the sternum. The dog was diagnosed as secondary spontaneous pneumothorax resulting from bacterial pneumonia. The chest tubes were placed on the right and left pleural cavity under general anesthesia. At 3 days after treatment, on a VD radiograph, air of right pleural cavity disappeared while left pleural cavity showed radiolucent area filled with air, and the heart was shift to the right. Therefore, the left tube thoracostomy was performed too. The right chest tube was maintained for 5 days and the left chest tube was maintained for 45 days. During the period, antibiotics and vitamin I were used for managing of bacterial pneumothorax and preventing of retroinfection through the tubes. As the result, bacterial pneumonia was well managed by medicines and secondary SP was completely treated that air in bilateral pleural cavity disappeared on radiographs. During the follow-up for 2 years, patient showed normal condition without recurrence.

Isolation and identification of a phenol-degrading bacterium from the sewage sludge (하수슬러지로부터 페놀분해세균의 분리 및 동정에 관한 연구)

  • Kim, Young-Jun;Lee, Suk-Won;Han, Gee-Bong
    • Journal of the Korea Organic Resources Recycling Association
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    • v.12 no.1
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    • pp.67-74
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    • 2004
  • A bacterium which grow on phenol as an only carbon and energy source was isolated from the sewage sludge at Nangi municipal wastewater treatment plant in Seoul. This bacterium was found to be a Gram negative rod with high motility, and well grew on 0.05%, 0.1%, and 0.15% of phenol. No matching strain was found from the result of the BBL test. Phylogenetic analysis of the strain by comparison of the 16s-rDNA has revealed that this bacterium has 99% of similarity with Stenotrophomonas maltophilia strain of Xanthomonas group, which belongs t the Gamma (${\gamma}$) subdivision of Proteobacteria. This strain has also shown 98% of similarity with nitrogen fixing bacterium MAGDE3 and Pseudomonas cissicola strain, and 97% of similarity with Stenotrophomonas sp. LMG198 and Xanthomonas cucurbitae.

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Aortic Root Replacement Using Aortic Homograft in Acute Bacterial Endocarditis One Case Report (심내막염 환자의 동종대동맥편을 이용한 대동맥 근부 치환술 - 1례 보고 -)

  • Im, Chang-Yeong;Lee, Heon-Jae
    • Journal of Chest Surgery
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    • v.30 no.8
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    • pp.819-822
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    • 1997
  • Aortic valve replacement with aortic allograft has been considered a treatment of choice for aortic valve disease secondary to bacterial endocarditis because of its good homodynamic performance and higher resistance to infection. The aortic root replacement technique might be superior to the subcoronary allograft implantation technique with regard to aortic regurgitation. A 46 yea,rs old male patient had acute aortic regurgitation with progressing heart failure secondary to acute bacterial endocarditis. The patient underwent emergent aortic root replacement using 20 mm aortic allograft. At operation, right coronary cusp perforation and heavy calcification of commissure between right and left coronary cusp were observed. The patient recovered well and postoperative echocardiography demonstrated no aortic regurgitation. Inflammatory signs were subsided after 8 weeks of antibiotics therapy. Medically uncontrolled acute bacterial endocarditis was treated successfully by aortic root replacement using aortic homograft.

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A Study of Air borne micrbes with Air ambient (광주지역 대기질과 낙하세균에 관한 연구)

  • 전의찬;노기환
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2002.04a
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    • pp.97-98
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    • 2002
  • 최근 들어 구제역과 같은 세균에 대한 경계와 관심이 늘어가고 있다. 하지만, 관심에 비하여 이에 대한 연구가 부족한 실정이고 대기질과 상호 연계한 연구는 더욱 미미한 상태이다. 따라서, 본 연구에서는 광주광역시의 시간대별 교통량과 대기질 그리고 낙하세균의 수를 함께 조사하여 상호연관성을 찾아보고자 하였다. 낙하세균은 탄저균이나 구제역처럼 전염성이나 인체에 미치는 영향은 크지 않지만 공중보건과 대기질 관리의 관점에서 이에 대한 정보 확보와 관련대책이 시급하다. (중략)

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Infected Abdominal Aortic Aneurysm (감염성 복부 대동맥류 -수술치험 1례 보고-)

  • 김경렬;최세영
    • Journal of Chest Surgery
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    • v.29 no.3
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    • pp.342-345
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    • 1996
  • Mycotic anuerysms are uncommon but it is a fulminant infectious process frequently resulting in rupture and death if not properly treated. Commonly known it as infected aneurysm caused by noncardiogenic bacteremia. We experienced a case of infected aneurysm of the abdominal aorta that ruptured into the retroperitoneum. A 57 year old man was admitted with lower back pain, fever and palpable mass. It was identified as an inf cted abdominal aneurysm with staphylococcal septicemia. He underwent resection of aneurysm and replacement with a prosthetic graft and prolonged postoperative organism-specific antibiotics therapy. He recovered well and discharged without complications postoperatively.

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