• Title/Summary/Keyword: 성장기 쥐

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Effect of Essential Fatty Acid Deficiency on Blood and Tissue Lipid Compositions (필수 지방산 결핍이 성장기 쥐의 혈액 및 조직의 지방조성에 미치는 영향)

  • Song, Ji-Hyun;Kim, Hae-Young;Choi, Hay-Mie
    • Journal of Nutrition and Health
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    • v.16 no.2
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    • pp.89-96
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    • 1983
  • Weanling male rats were fed a semi - synthetic diet containing either 10% corn oil, or 10% hydrogenated coconut oil (HCO) for 5 weeks. They were analyzed for plasma, liver, heart, testis, kidney and adrenal lipid compositions ; total lipids, total cholesterol, phospholipid, and triglyceride. The rats fed essential fatty acids deficient diet grew comparably with corn oil group and did not any dermal symptoms of EFAs deficiency. The most remarkable changes found in lipids of rats in experimental groups were ; (1) an increase in the concentration of plasma TG and liver TG in HCO group. (2) a decrease in the concentration of plasma PL and an increase in the concentration of testis PL of HCO group. (3) A decrease in cholesterol level of testis, kidney and adrenal of HCO group. Although this study did not show the profound EFA deficiency in weanling rats, this study showed the possibility of early nutrition affecting subsequent development in various tissues.

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Effect of Estrone Treatment on Proteinuria in Maturing Lean and Obese Male SHR/Mcc-cp Rats (Estrone 투여가 SHR/Mcc-cp 계통의 정상체중과 비만한 성장기 숫쥐들에서 단백뇨 증상에 미치는 영향)

  • Park, Sonhee
    • Journal of Nutrition and Health
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    • v.23 no.6
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    • pp.451-458
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    • 1990
  • Lean and obese male spontaneously hypertensive(SHR/Mcc-cp) rats were fed a ground rat chow diet with or without 0.001% estrone added from 6 to 18 weeks of age. Urine samples were collected weekly with 24 hour fasting. Both control lean and obese rats showed significantly higher urinary protein than their estrone treated counterparts. Treatment with 0.001% estrone diet was found to reduced the proteinuria in the maturing lean and obese SHR/Mcc-cp rats. Peaks in urinary protein level were noted at 16 weeks of age in both lean and obese control rats. Both control and estrone treated lean rats showed higher proteinuria than the obese rats. Therefore, obesity does not appear to be a contributing factor to the proteinuria in young male SHR/Mcc-cp rats.

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The Effect of Feeding Frequency on the Growth and Composition of Individual Organs in Rats (식이섭취 빈도수가 흰쥐의 성장 및 각 기관의 조성에 미치는 영향)

  • Jung, Eun-Hee;Lee, Yeon-Sook;Chun, Sung-Kyu
    • Journal of Nutrition and Health
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    • v.18 no.1
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    • pp.14-22
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    • 1985
  • The effect of feeding Sequency on the growth and composition of individual organs in young and adult rae were investigated Young and adult male rats were received 20% casein diet by one-meal, three-meals per day or ad libitum for 24 days The rats were tilled and analyzed with regard to the composition of individual organs DNA, RNA, Protein lipid and water content of the liver, kidney, speen were determined In both young and adult rats, the body weight gain of the three- meal group was similar to that of ad -lib. group, but the body weight gain and food intake of the one - meal group were lower than those of others. In case of young rats, DNA, RNA and protein content of liver, kidney and spleen was less in one- meal group than in ad-lib group : their compositions per DNA were, however, similar in both instances In case of adult rats, the weight of liver increased significantly and their composition per DNA except lipid increased in one - meal group, but the total DNA content in the liver did not show any significant difference. The size of stomach and intestine tend to increase in meal -feeding group, but the serum cholesterol showed no significant change.

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Effect of Methionine Supplementation on Glutathione Peroxidase Activity in Young and Old Murine Tissues (성장기의 쥐와 늙은 쥐 조직의 Glutathione Peroxidase 활성에 대한 Methionine 투여의 효과)

  • Cha-Kwon Chung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.3
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    • pp.429-435
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    • 1994
  • The effect of methionine (Met) supplementation on glutathione peroxidase(GSHPx) activity in young and 14 month-old rat and mice was investigated. GSHPx activity was more enhanced by methionine supplementation in young rats when selenium (Se) was given as selenite than given in the form of selenomethione (Se-Met). However, GSHPx activity was not influenced by Met supplementation in the old rats. When diets were low in Se, the biopotency of ht eenzyme by Met was facilitated. No significant differences in GSHPx activity was observed with Met supplement in growing mice when Met was given 0.3% and 0.8% iin the diet at high levels of Se (2 ppm). The peak GSHPx in liver and kidney occurred at day 18, thereafter it decreased. Particularly, the liver GSHPx at day 18 increased 4.2 times than that at day 4 by 0.5% Met supplementation, while the unsupplemented group remained only 2.5 times increase. It is considered that in some tissues Met requirement may be met by Se-Met when rats were fed a diet suboptimal in Met. In addition, at lower levels of Se the utilization of Se is more enhanced by Met than at higher levels of dietary Se. Therefore, GSHPx activity may be influenced greatly by Met status along with dietary Se.

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Sexual Maturation and Spawning Characteristics in Greenling, Hexagrammos otakii of the West Coast in Korea (서해산 쥐노래미, Hexagrammos otakii의 성성숙과 산란 특성)

  • 강희웅;정의영;김종화
    • Journal of Aquaculture
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    • v.17 no.1
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    • pp.30-38
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    • 2004
  • To estimate the spawning period the annual change of gonadosomatic index (GSI) were examined from January 2000 to December 2001. Fecundity, spawning frequency and egg diameter were measured by ocular observation. Germ cell differentiation during gametogenesis, the reproductive cycle and the first sexual maturity of greenling Hexagrammos otakii were observed under light microscopy from January to December, 2000. GSI began to increase in August and reached the maximum in November when ovary was getting mature. The reproductive cycle of H. otakii can be divided into five successive stages in females: early growing stage (July), late growing stage (July to August), mature stage (September to October), ripe and spent stage (September to December), and recovery and resting stage (December to June). Males showed four successive stages : growing (June to August), mature (August to October), ripe and spent (September to December), and recovery and resting stage (December to May). According to the frequency distributions of egg diameter in spawning season, H. otakii could be one of polycyclic species spawning 2 times or more during one spawning season. Number of total eggs and mature eggs in the absolute fecundity were related to the standard length and body weight, respectively. Number of total eggs and mature eggs in relative fecundity were also proportional to the standard length, but rather these numbers decreased with body weight. Percentages of first sexual maturity of females and males in greenling were over 50% from 19.1 to 21.1cm in length, and 100% for fish over 25.1cm in length. Therefore, both sexes are ready to reproduce after one year old.

Effects of combined intervention of isoflavone supplementation and exercise on bone metabolism in growing rats (이소플라본 보충과 운동의 병행이 성장기 쥐의 골격대사에 미치는 영향)

  • Jung, Yun-Jung;Choi, Mi-Ja
    • Journal of Nutrition and Health
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    • v.48 no.2
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    • pp.149-156
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    • 2015
  • Purpose: This study examined the effects of combined intervention of isoflavones and exercise on bone mineral density, bone mineral content, and biochemical bone markers. Methods: Forty rats were divided into four groups; Control, Isoflavones (IF), Isoflavones + Running (IFR), and Isoflavones + Swimming (IFS). All of the rats in this study were fed an experimental diet and deionized water ad libitum for nine weeks. Bone mineral density (BMD) and bone mineral content (BMC) were estimated using PIXImus (GE Lunar Co, Wisconsin.) in spine and femur nine weeks after feeding or training. Results: The combined intervention did not affect weight gain, mean food intake, or food efficiency ratio. The serum concentrations of ALP and osteocalcin were not significantly different by combined intervention. The urinary DPD crosslinks values were not significantly different by combined intervention. There were no significant differences in serum PTH, calcitonin, and estradiol among all groups. Spine BMD, spine BMC and femur BMC were not significantly different by combined intervention. However, femur BMD was significantly higher in the IFR group than in the control group. Compared with the control group, spine BMD, spine BMC, and femur BMD per weight were markedly increased in the isoflavones supplementation and combined intervention group. In addition, femur BMC per weight was significantly higher in the IFS group than in the control group. Compared with the isoflavones supplemented group, BMD and BMC were not significantly different by combined intervention. Conclusion: It can be concluded that isoflavones supplementation or combined intervention of isoflavone and exercise had a beneficial effect on spine and femur peak bone mass in growing female rats.