• Korean Journal of Clinical Laboratory Science
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• v.55 no.3
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• pp.203-212
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• 2023

Since the coronavirus disease-2019 (COVID-19) outbreak, it has been generally believed that a medical technologists (MTs) are supposed to perform polymerase chain reaction tests and next-generation sequencing (NGS) in the hospitals. However, many do not recognize that the duty of MT for clinical genetic testing has not been stated in the Medical Laws (72.5% for MT, N=200; 62.8% for students, N=123). In this regard, to evaluate the feasibility of MT's role for NGS genetic testing, we requested our subjects to fill out an online survey and analyzed the data. Among them, it shows that the scope of MT's role, including NGS performance should include clinical genetic testing (99.5% for MT, N=200; 86.8% for students, N=123). Also, questions on clinical genetics, which is associated with both cellular genetics and molecular genetic questions should be included in the National MT License Problem Bank (97.5% for MT; 71.4% for students). Based on these results, the Korean Association of Medical Technologists needs to cooperate synergically with the Academic Association of Biomedical Laboratory Science with respect to genetic education and legislation for the future benefit of both MTs and students.

• Proceedings of the Korean Society of Tobacco Science Conference
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• 1997.10a
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• pp.79-90
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• 1997

The world-wide cigarette market is becoming increasingly regulated. This involves restrictions on the freedom to advertise, restrictions on where people can smoke, and in some ways of most importance, limits on cigarette smoke deliveries. In particular, in an increasingly large number of countries maximum tar legislation is being enacted. In many cases, such as the European Union, this type of legislation is progressive and over time it is entirely conceivable that maximum permitted tar deliveries will be reduced to as low as 5 mg, possibly with additional restrictions on smoke nicotine deliveries. In addition, the pace of change is increasing as more and more countries embark on tar reduction programmes. The key challenge facing the cigarette industry is to manage these changes in such a way which ensures that product acceptability is maintained at as high a level as is possible in these circumstances. There are a number of ways of achieving this involving filter ventilation, modifying blends and using different filter constructions The real innovation comes when combining these in a way that gives the most acceptable balance of all these competing variables as far as the smoker is concerned. Undoubtedly, the nature of the filter is of crucial importance in designing the most acceptable low tar products, and this paper will discuss some of the filter types which are currently in use in the various low tar markets around the world. Also, some thoughts about the future in terms of new filter developments will be presented.

• Journal of the Korean Geotechnical Society
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• v.22 no.1
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• pp.35-44
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• 2006

In general typically granular soils contain a certain amount of fines. It is also widely recognized that foundation soils under working loads show highly non-linear behavior from very early stages of loading. In the present study, a series of laboratory tests with sands of different silt contents are conducted and methods to assess strength and stiffiness characteristics are proposed. Modified hyperbolic stress-strain model is used to analyze non-linearity of silty sands in terms of non-linear Degradation parameters f and g as a function of silt contents and Relative density Dr. Stress-strain curves were obtained from a series of triaxial tests on sands containing different amounts of silt. Initial shear modulus, which is used to normalize Degradation modulus of silty sands, was determined from resonant column test results. From the laboratory test results, it was observed that, as the Relative density increases, values of f decrease and those of g increase. In addition, it was found that values of f and g increase and decrease respectively as a Skeleton void ratio $(e_{sk})$ increases.

• Journal of the Korean Geotechnical Society
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• v.23 no.6
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• pp.97-102
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• 2007

Though the stability analysis of soil slopes widely employs the limit equilibrium method, the study on the jointed rock slopes must consider the direction of joint and the characteristics of Joint at the same time. This study analyzes the result of the change in the factors which show the characteristics of discontinuity and the shape factor of rock slopes, and so on, in an attempt to validate the propriety as to the interpretation of jointed rock slope stability which uses the general finite element program. First, the difference depending on the flow rules was compared, and the factor effect study was conducted. The selected independent variables included the direction of joint which displays the mechanical characteristics of discontinuity, adhesive cohesion, friction angle, the inclination and height of rock slope which reveal the shape of slope and surcharge load. And the horizontal displacement was numerically interpreted at the 1/3 point below the slope, a dependent variable, to compare the relative degree of factor effects. The findings of study on factor effects led to the validation that the result of horizontal displacement for each factor satisfied various engineering characteristics, making it possible to be applied to stability interpretation of jointed rock slope. A modelling is possible, which considers the application of the result of real geotechnical surveys & laboratory studies and the non-linear characteristics when designing the rock slope. In addition, the stress change which may result from the natural disaster, such as precipitation, and the construction, can be expressed. Furthermore, as the complicated rock condition and the ground supporting effect can be considered through FEM, it is considered to be very useful in making an engineering decision on the cut-slope, reinforcement and so on.

• Journal of the Korean Geotechnical Society
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• v.24 no.12
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• pp.65-73
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• 2008

In the current practice for slope stability problem in Japan, the shear strength, $\tau$, mobilized along the failure surface is usually estimated based on an empirical approximation in which the cohesion, c, is assumed to be equal to the soil thickness above the supposed slip surface, d(m). This approximation is advantageous in that the result of stability analysis is not influenced by the designers in charge. However, since the methodology has little theoretical background, the cohesion may often be grossly overestimated, and conversely the angle of shear resistance, $\phi$, is significantly underestimated, when the soil thickness above the supposed slip surface is quite large. In this paper, a case record of natural slope failure that took place in Hyogo Prefecture in 2007, is described in detail for the case in which the shear strength along the collapsed surface was carefully examined in a series of direct shear box (DSB) tests by considering the effects of in-situ shear stress along the slip surface. It is demonstrated that the factor of safety agrees with that of in-situ conditions when the shear strength from this kind of DSB test was employed for the back-analysis of the slope failure.

• Journal of the Korean Geotechnical Society
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• v.24 no.7
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• pp.61-73
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• 2008

Piles of a bridge pier are connected with the column through the pile cap (footing). Behavior of the pile foundation can be different according to the connection method between piles and the pile cap. Connection methods between pile heads and the pile cap are divided into two groups : rigid connections and hinge connections. Domestic design code has been specified to use rigid connection method for the highway bridge. In the rigid connection method, maximum bending moment of a pile occurs at the pile head and this helps the pile to prevent the excessive displacement. Rigid methods are also good to improve the seismic performance. However, some specifications prescribe that conservative results through investigations of both the fixed-head condition and the free-head condition should be reflected in the design. This statement may induce an over-estimated design for the bridge which has high-quality structures with casing covered drilled shafts and the PC-house contained pile cap. Because the assumption of free-head conditions (hinge connections) is unreal for the elevated pile cap system with multiple piles of the long span sea-crossing bridges. On the other hand, elastic displacement method to evaluate the pile reactions under the pile cap is not suitable for this type of bridges due to impractical assumptions. So, full modeling techniques which analyze the superstructure and the substructure simultaneously should be performed. Loads and stress state of the large diameter drilled shaft and the pile cap for Incheon Bridge which will be the longest bridge of Korea were investigated through the full modeling for rigid connection conditions.

• Journal of the Korean Geotechnical Society
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• v.25 no.4
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• pp.19-29
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• 2009

In this study, a numerical analysis was performed to predict the sequential behavior of anchored retaining wall where the failure accident took place, and verified accuracy of prediction through the comparisons between prediction and field measurement. The emphasis was given to the wall behaviors and the variation of sliding surface based on the two different methods of elasto-plastic and finite element (shear strength reduction technique). Through the comparison study, it is shown that the bending moment and the soil pressure at construction stages produce quite similar results in both the elasto-plastic and finite element method. However, predicted wall deflections using elasto-plastic method show underestimate results compared with measured deflections. This demonstrates that the elasto-plastic method does not clearly consider the influence of soil-wall-reinforcement interaction, so that the tension force (anchor force and earth pressure) on the wall is overestimated. Based on the results obtained, it is found that finite element method using shear strength reduction method can be effectively used to perform the back calculation analysis in the anchored retaining wall, whereas elasto-plastic method can be applicable to the preliminary design of retaining wall with suitable safety factor.

• Journal of the Korean Geotechnical Society
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• v.24 no.5
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• pp.129-137
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• 2008

An active application of concrete track is being expected far the future constructions of Korean railroad. In comparison with the existing ballasted tract, a concrete track is very susceptible for the settlement, since its rehabilitation requires much time and cost. When a concrete track is constructed on fine-grained subgrade soil, excessive cumulative plastic settlements due to repetitive train road may occur. In this case, the settlement of the concrete track may be effectively reduced by installing a small number of small-diameter piles beneath the track. This paper presents the effect of pile installation on the reduction of cumulative plastic settlement of concrete track. A method combining experiential equation and numerical method is proposed. Using an existing experiential equation and the estimated earth pressure distribution, the cumulative plastic strain was calculated. From the results, it is verified that the effects of the pile installation is significant to effectively reduce the cumulative plastic settlement of concrete track. The reduction effects of the cumulative plastic settlement according to the pile number and pile arrangement are presented.

• Journal of the Korean Geotechnical Society
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• v.24 no.5
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• pp.65-78
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• 2008

In case of cut-slopes or shallow-depth tunnels, sliding along with discontinuities or rotation could play a critical role in judging stability. Although numerical analysis is widely used to check the stability of these cut-slopes and shallow-depth tunnels in early design process, common analysis programs are based on continuum model. Performing continuum model analysis regarding discontinuities is possible by reducing overall strength of jointed rock mass. It is also possible by applying ubiquitous joint model to Mohr-Coulomb failure criteria. In numerical analysis of cut-slope, main geotechnical properties such as cohesion, friction angle and elastic modulus can be evaluated by empirical equations. This study tried to compare two main systems, RMR and GSI system by applying them to in-situ hazardous cut-slopes. In addition, this study applied ubiquitous joint model to simulation model with inputs derived by RMR and GSI system to compare with displacements obtained by in-situ monitoring. To sum up, numerical analysis mixed with GSI inputs and ubiquitous joint model proved to provide most reliable results which were similar to actual displacements and their patterns.

• Journal of the Korean Geotechnical Society
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• v.24 no.6
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• pp.57-67
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• 2008

Two test methods, nonrepetitive plate loading test (NPLT) and repetitive plate loading test (RPLT) are being used to control the quality of compaction through the evaluation of the stiffness of subgrade soils in the Korea railway industry. Subgrade reaction modulus ($k_{30}$) from the NPLT and strain modulus ($E_v$) from the RPLT are the index values to check them. The methods have similar aspects, but they differ in the modulus evaluation method, the numbers of loading stage, termination procedures, etc. This paper analyses the differences of the two test methods and evaluates the relationship between subgrade reaction modulus and strain modulus. In order to develop the relationship, total 22 tests were performed including the NPLT and the RPLT at the 6 original grounds, and 5 upper or lower subgrades in Kyungbu High Speed Railway II stage construction sites. According to the soil conditions, the relationship between subgrade reaction modulus and strain modulus was proposed with corrections by considering strain states, mean confining pressures, and Poisson's ratio.