• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.66-66
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• 2003

목적 : 선량측정의 정확성을 향상시키기 위하여 물 흡수선량 표준에 토대를 두고 있는 표준측정법, AAPM TG-51과 IAEA TRS-398, 이 발표되어 선량측정의 파라다임이 변화하고 있다. 본 연구에서는 이들 대표적인 표준측정법에 대하여 사용자 편의성을 고려하여 웹에 기반한 선량교정 프로그램을 개발하고자 한다. 대상 및 방법 : 미국의학물리학회 AAPM TG-51과 국제원자력기구 IAEA TRS-398 표준측정법에 선량교정 프로그램은 Microsoft IIS 6.0 웹서버와 .NET 플렛폼상에서 Visual Studio. NET 도구를 사용하여 개발하였다. 개발언어로는 C# 언어를 사용하였고 각 표준측정법에 대한 선량교정 작업서는 ASP. NET 페이지로 작성하였다. 웹페이지와 산량 교정 모듈을 분리하여서 개발 후 유지보수가 쉽게 설계하였다. 또한 기준점에서의 선량 계상에 사용하는 모든 물리적인 파라미터와 데이터는 데이터베이스에 저장하였다. 이로써 향후 수식체계의 변화 또는 물리적인 데이터의 변화로 인한 프로그램 수정이 최소화하도록 하였다. 결과 : 이들 표준측정법은 모두 물 흡수선량 교정인수에 토대를 두고 있으나 측정 조건 및 물리적인 자료 에 있어 약간의 차이를 보이고 있다. 그러므로 각 표준측정법간의 유사점 및 차이점을 비교 분석하기가 용이하였다. 그리고 개발된 프로그램을 이용하여 표준측정법에서 제시된 선량교정 작업서에 따라 선량 교정을 수행한 교정 결과 데이터를 XML 파일 형식으로 저장하여 이전의 측정 자료를 관리할 수 있게 하였다. 이 과거 측정 자료를 사용하여 출력 선량 교정의 변화 및 기타 중요한 물리적인 데이터 값의 변화를 분석할 수 있다. 결론 : 두 표준측정법에 대한 선량교정 프로그램은 사용자가 선호하는 표준측정법을 선택할 수 있고, 웹에 토대를 두고 있어 프로그램으로 전국 방사선종양학과의 방사선치료기기의 출력 및 물리적인 변화에 대한 자료를 비교 분석하기 용이하고 수작업으로 인해 발생할 수 있는 실수 및 오차를 줄일 수 있다. 또한 개발된 프로그램의 활용을 통하여 국내 실정에 적합한 물 흡수선량 표준에 기반한 표준측정법 개발에 토대를 마련하는데 있어 기여할 것으로 사료된다.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.38-38
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• 2003

목적 : 방사선 수술의 목적은 병소에 최대한의 방사선을 조사하고, 주위의 정상조직에는 가능한 적은 양의 방사선을 조사하는 것이다. 이러한 목적을 만족시키기 위해 방사선 수술계획자는 계획시 isocenter의 위치와 개수, 콜리메이터 크기를 변화시켜 가며, 주어진 병소에 맞는 선량분포를 획득해 방사선 수술효과를 최대화시키는 수술계획을 수립한다. 본 연구에서는 다양한 모양의 병소에 대해 자동적으로 isocenter를 위치시켜 수술 계획시 도움이 될 수 있도록 임의의 병소 모델들에 대해 위의 변수들을 변화시켜 가며 얻어지는 선량분포를 비교 분석하였다. 방법 : 본 연구에서는 임의로 정의한 계산 영역내에 다면체를 병소로 가정하여 연구를 수행하였다. 방사선 수술시 하나의 isocenter에서 얻어지는 선량분포는 구형으로 근사할 수 있으므로 하나의 isocenter를 구로 근사하여, 각 병소 모델 내에 콜리메이터 크기를 변화해가며 가능한 많은 영역을 포함하도록 isocenter를 배치시켰다. 이후 구형선량모델을 사용해 선량분포를 획득하여 병소와 정상조직간의 DVH(Dose Volume histogram)와 각 병소 모델에 대한 통일 평면상의 선량분포를 비교 분석하였다. 결과 ; 임의의 다양한 종양 모델에 대한 50%의 등선량 곡선내에서 세 가지의 빔관련 변수들을 변화시킨 결과, 종양이 없는 정상 조직에서는 선량분포가 극히 낮았으며, 콜리메이터의 크기에 따른 isocenter 의 개수가 변화하는 것을 확인할 수 있었고, 이 경우 한 종양모델에서의 깊이에 따른 선량 분포는 크게 차이가 나지 않았다. 그리고, isocenter의 개수가 변화함에 따라 선량곡선이 변하는 것을 확인할 수 있었다. 결론 : 빔관련 변수인 콜리메이터 크기, isocenter 개수, 거리등은 어느 일정 정도를 넘기면, 병소내 선량 분포에 크게 기여하지 않는다는 점을 감안하여 빔관련 변수들을 최소로 고려하므로써 계획시 소모되는 시간 과 노력을 많이 줄일 수 있을 것이며, 또한 각 병소 모델에 대한 최적의 구형선량모델에서 공통적인 규칙성을 찾는 것과 실제 병소의 모양을 간단한 모양으로 근사화 시킨다면 자동적 선량모델을 이루는데 많은 도움이 되고, 이로 인해 효율적인 치료계획작업이 이루어질 것이라 사료된다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.12
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• pp.1711-1717
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• 2020

X-ray of up to 9MeV are used for container inspection. X-ray intensity must be maintained stably regardless of changes in time. If dose is not constant, it may affect the image quality, and as a result, may affect the inspection of abnormal cargo. Therefore, to acquire high-quality images, continuous dose monitoring is required. In this study, the ion-chamber based device was developed for monitoring the dose change in high-energy x-ray. And to estimate the performance of signal-processing device change according to the environmental change, the output changing due to the change of temperature and humidity was observed. In addition, verification of the device was performed by measuring the output change. As a result of the measurement, there was no significant difference in performance due to changes in temperature and humidity, and the change in output according to the change in exposure was linear. Therefore, it was found that the developed device is suitable for the dose monitoring of high-energy x-ray.

• Journal of Yeungnam Medical Science
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• v.4 no.2
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• pp.89-96
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• 1987

Using same TDE factors, the authors studied the effects of whole abdominal irradiation on body weight and peripheral blood picture in $30{\pm}3$ day old mice. Fractions of 100 and 200 cGy were given five times a week to the final TDF factors l7, 33, and 49. Total 80 mice were irradiated with orthovoltage x-ray machine. Our results can be summarized as follows : There were no significant differences by sex. Body weight was progressively decreased by the duration for irradiation, but no remarkable difference by fractional dose. Hemoglobin level showed no remarkble change by fractional dose or TDF factors. Leukopenic changes showed that severity of decrease seems to be more related to TDF factors. There were no significant changes of differential count by TDF factors of total doses.

• Progress in Medical Physics
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• v.9 no.4
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• pp.247-257
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• 1998

For effective radiotherapy, it should always be considered that calculation of different dose distribution in heterogenous tissue is important particularly on lung which has low density and large volume. To take precise dose distribution of 6MV X-ray in the thoracic cage, the authors had made a tissue equivalent phantom for thorax, measured dose distribution by thermoluminescent dosimeter and mm dosimeter, and derived methmetical equation coincided with provided theoretical formula. In comparision with isodose curve on case of homogeneous soft tissue, dose of heterogeneous lung tissue had been shown increase about 4% per cm depth on one and multiportal field, less than 15% difference on rotation field for esophagus, and around 20% difference on rotation field for lung according to the degree of rotation angle that must be corrected by dose compensation.

• Journal of radiological science and technology
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• v.40 no.3
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• pp.415-421
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• 2017

In the case of radiation therapy for prostate cancer, a balloon infused with a certain amount of air through the anus is used to reduce rectal dose. Because of the reason, radiation therapy for prostate cancer has acquired CBCT for daily image induction. In order to maintain the anatomical structure most similar to the first CT taken before treatment, it is pretreated, but it can not be said to be perfectly consistent. In two actual treatment regimens, the volume of the bladder was measured as 45.82 cc and 63.43 cc, and the equivalent diameter was 4.4 cm and 4.9 cm. As a result of this study, the mean volume of the bladder was estimated to be 56.2 cc, 105.6 cc by 20 CBCT. The mean dose of CBCT was 1.74% and the mean Bladder mean dose was 96.67%. In case B, PTV mean dose was 4.31%, Bladder mean Dose was estimated to be 97.35%. The changes in the volume of the bladder resulted in changes in the dose of PTV and bladder. The correlation coefficient of bladder dose according to the change of bladder volume showed linearity of mean dose $R^2=-0.94$. The correlation coefficient of the PTV dose according to the volume change of the bladder showed linearity of mean dose $R^2=0.04$. It was found that the dose change of PTV was larger than that of bladder according to the change of bladder volume.

• Journal of the Korean Society of Radiology
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• v.6 no.6
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• pp.473-476
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• 2012

The PET-MRI which has been installed and being managed recently uses both magnetic field and radiation. Most radiation workers wear a thermoluminescenct dosimeter (TLD) as a personal radiation dosimeter, and the TLD is affected both by a magnetic field and radiation. In this research, the same amount of X-ray was applied to 36 TLDs, and the changes in the dose of the 32 TLDs exposed to magnetic field at the location where its intensity of the magnetic resonance imaging (MRI) was about 5000 Gauss for eight hours with one-hour unit and that of the four TLDs not exposed to magnetic field were compared and checked. The measurement result showed that exposure dose of the TLD attached to the MRI changed irregularly depending on the amount of exposure time. Therefore, the TLD whose amount of changes little in the environment of a MRI is demanded to be developed.

• Proceedings of the Korea Contents Association Conference
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• 2011.05a
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• pp.187-188
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• 2011

저 에너지 방사선검사 시 부득이하게 방사선 노출을 받게 되는 방사선 작업종사자나 환자의 보호자가 위치와 거리에 따른 방사선 피폭 선량의 감소 방안을 알아보고자 한다. Ion chamber mode 2026c, Reader기 20X6-1800을 사용하여 구강내 검사와 구강외 검사의 각각 검사실과 조정실에서의 관전압의 변화, 관전류와 조사시간의 변화, 조사방향의 변화에 따라 선량을 측정하였다. 그 결과 검사실 안에서는 최고선량이 평균 $702.8{\mu}R$으로 측정 되었으며, 조정실 안에서 측정하였을 경우 $20{\mu}R$이하의 낮은 선량을 보였으며, 후방검사보다 측방검사가 낮은 선량으로 나타났다. 방사선검사 시 위치와 거리에 따른 조사선량을 비교 분석하여, 적절한 거리 확보와 조사되는 중심방사선을 기준으로 측방($90{\sim}135^{\circ}$)에 위치함으로써 방사선 방어에 도움을 줄 것이며, 차폐문을 이용하여 방사선 피폭으로부터 감소 효과를 볼 수 있을 것이다.

• Progress in Medical Physics
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• v.21 no.2
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• pp.218-222
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• 2010

As radiation is irradiated from various directions in intensity modulated radiation therapy (IMRT), longer treatment time than conventional treatment method is taken. In case of the patients who have problem to keep same posture for long time because of pain and injury, reducing treatment time through increased dose rate is a way for effective treatment. This study measured and found out the variation of dose and dose distribution in accordance with dose rate variation. IMRT treatment plan was set up to investigate from 5 directions - $0^{\circ}$, $72^{\circ}$, $144^{\circ}$, $216^{\circ}$, $288^{\circ}$ - using ECLIPSE system (Varian, SomaVision 6.5, USA). To confirm dose and dose rate in accordance with dose rate variation, dose rate was set up as 100, 300, 500 MU/min, and dose and dose distribution were measured using ionization chamber (PTW, TN31014) and film dosimeter (EDR2, Kodak). At this time, film dosimeter was inserted into acrylic phantom, then installed to run parallel with beam's irradiating direction, 21EX-S (Varian, USA) was utilized as linear accelerator for irradiation. The measured film dosimeter was analyzed using VXR-16 (Vidar System Corporation) to confirm dose distribution.

• The Journal of Korean Society for Radiation Therapy
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• v.24 no.1
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• pp.1-10
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• 2012

Purpose: To evaluate dose distribution differences when the dose rates are randomly changed in intensity-modulated radiation therapy using a dynamic multileafcollimator. Materials and Methods: Two IMRT treatment plans including small-field and large-field plans were made using a commercial treatment planning system (Eclipse, Varian, Palo Alto, CA). Each plan had three sub-plans according to various dose rates of 100, 400, and 600 MU/min. A chamber array (2D-Array Seven729, PTW-Freiburg) was positioned between solid water phantom slabs to give measurement depth of 5 cm and backscattering depth of 5 cm. Beam deliveries were performed on the array detector using a 6 MV beam of a linear accelerator (Clinac 21EX, Varian, Palo Alto, CA) equipped with 120-leaf MLC (Millenium 120, Varian). At first, the beam was delivered with same dose rates as planned to obtain reference values. After the standard measurements, dose rates were then changed as follows: 1) for plans with 100 MU/min, dose rate was varied to 200, 300, 400, 500 and 600 MU/min, 2) for plans with 400 MU/min, dose rate was varied to 100, 200, 300, 500 and 600 MU/min, 3) for plans with 600 MU/min, dose rate was varied to 100, 200, 300, 400 and 500 MU/min. Finally, using an analysis software (Verisoft 3.1, PTW-Freiburg), the dose difference and distribution between the reference and dose-rate-varied measurements was evaluated. Results: For the small field plan, the local dose differences were -0.8, -1.1, -1.3, -1.5, and -1.6% for the dose rate of 200, 300, 400, 500, 600 MU/min, respectively (for 100 MU/min reference), +0.9, +0.3, +0.1, -0.2, and -0.2% for the dose rate of 100, 200, 300, 500, 600 MU/min, respectively (for 400 MU/min reference) and +1.4, +0.8, +0.5, +0.3, and +0.2% for the dose rate of 100, 200, 300, 400, 500 MU/min, respectively (for 600 MU/min reference). On the other hand, for the large field plan, the pass-rate differences were -1.3, -1.6, -1.8, -2.0, and -2.4% for the dose rate of 200, 300, 400, 500, 600 MU/min, respectively (for 100 MU/min reference), +2.0, +1.8, +0.5, -1.2, and -1.6% for the dose rate of 100, 200, 300, 500, 600 MU/min, respectively (for 400 MU/min reference) and +1.5, +1.9, +1.7, +1.9, and +1.2% for the dose rate of 100, 200, 300, 400, 500 MU/min, respectively (for 600 MU/min reference). In short, the dose difference of dose-rate variation was measured to the -2.4~+2.0%. Conclusion: Using the Varian linear accelerator with 120 MLC, the IMRT dose distribution is differed a little <(${\pm}3%$) even though the dose-rate is changed.