• Title/Summary/Keyword: 선량반응

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A Study on the Exposure Parameter and the Patient Dose for Digital Radiography System in Dae Goo (디지털 방사선의학에서의 조사선량 설정과 인지에 대한 실태 - 대구 경북지역을 중심으로 -)

  • Jo, Gwang-Ho;Kang, Yeong-Han;Kim, Bu-Sun
    • Journal of radiological science and technology
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    • v.31 no.2
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    • pp.177-182
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    • 2008
  • Digital imaging for general rediography has many advantages over the film/screen systems, including a wider dynamic range and the ability to manipulate the images produced. The wider range means that acceptable images may by acquired at a range of dose levels, and therefore repeat exposures can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency can be reduced. Digital imaging can result in the over use of radiation, however, because there is a tendency for images to be acquired at too high a dose. We investigated the actual exposure dose conditions on general radiography and a questionnaire survey was conducted with radiotechnologiest at medical institutions using digital radiology system. As a results, the dose of exposure was not controlled with patient's figure and dose optimization but was controlled by worker's convenience and image quality. Radio-technologiests often set up the exposure dose regardless of patient figure and body part to be examined. Many organizations, such as the International Commission on Radiological Protection, recommend to keep the dose as low as possible. In addition, they strongly recommend to keep the optimal but minimal dosage by proper training programs and constant quality control, including frequent patient dose evaluations and education.

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Fast Neutron Dosimetry with Two Threshold Detectors in Criticality Accidents of Nuclear Reactors

  • Ro, Seung-Gy
    • Nuclear Engineering and Technology
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    • v.2 no.2
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    • pp.85-95
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    • 1970
  • An attempt has been made to do interpretation of the fast neutron dose with two threshold detectors incorporated with the Harwell criticality locket. This method is based on the assumption that the spectral distribution of fission neutrons in criticality accidents may be governed by one spectral parameter. The surface-absorbed dose for a unit fission neutron fluence seems to be insensitive to spectral shifts of the fission neutron spectrum. The average cross-sections for the activation detectors, however, are considerably changed with the neutron spectral shape, which may lead to a large error in calculating the dose from the reaction rate if one uses a fixed value for the average cross sections regardless of the neutron spectral distribution. Besides, the doses calculated from three representative formulae for fission neutron spectra have been compared : these formulae are Watt, Cranberg at al. and Maxwellian forms. The results obtained front the Maxwellian formula show a departure from the Watt and Cranberg's, both being similarly close.

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The Effect of Thin Teflon on TLD Response for in vivo Dosimetry of Radiotherapy (생체 내 흡수선량 측정을 위한, 얇은 테프론의 TLD 반응감도에 대한 효과성)

  • Kim, Sookil;Yum, Ha-Young;Jeong, Tae-Sig;Moon, Chang-Woo
    • Progress in Medical Physics
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    • v.14 no.2
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    • pp.74-80
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    • 2003
  • The purpose of this study was to evaluate the performance of the teflon encapsulated TLD rod, which may be used in nuclear medicine for the direct in vivo measurements of radiation dose. We analyzed the influence of teflon encapsulation for measuring absorbed dose. An experiment was carried out to evaluate and observe the response of a LiF TLD-100 rod in a thin-wall teflon capsule at different depths in a solid phantom. An adult anthropomorphic phantom was used to measure the absorbed dose using thin teflon encapsulated TLD. The measurements of PDD-, and TMR in solid phantom and athe bsorbed dose in humanoid phantom performed with normal TLD were compared with values obtained by teflon encapsulated TLD. It was demonstrated that the difference of TL response of LiF in phantom with and without teflon thin-wall capsule was less than 3% under the same conditions beyond the build-up region. However, significant differences were observed near the phantom surface because of the build-up effect caused by the thin-wall thickness of the teflon capsule. Thus, our study showed that the contribution of teflon thin-wall capsule to TLD response for the megavoltage photon beams was negligible and that it did not significantly effect dose measurement. The teflon encapsulated TLD described in this work has been proven to be appropriate for in vivo dosimetry in therapeutic environments.

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Investigation of Response of Several Neutron Surveymeters by a DT Neutron Generator (DT 중성자 발생기에 의한 중성자 검출기 반응도 조사)

  • Kim, Sang-In;Jang, In-Su;Kim, Jang-Lyul;Lee, Jung-Il;Kim, Bong-Hwan
    • Journal of Radiation Protection and Research
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    • v.37 no.1
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    • pp.35-40
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    • 2012
  • Several neutron measuring devices were tested under the neutron fields characterized with two distinct kinds of thermal and fast neutron spectrum. These neutron fields were constructed by the mixing of both thermal neutron fields and fast neutron fields. The thermal neutron field was constructed using by a graphite pile with eight AmBe neutron sources. The fast neutron field of 14 MeV was made by a DT neutron generator. In order to change the fraction of fast neutron fluence rate in each neutron fields, a neutron generator was placed in the thermal neutron field at 50 cm and 150 cm from the reference position. The polyethylene neutron collimator was used to make moderated 14 MeV neutron field. These neutron spectra were measured by using a Bonner sphere system with an LiI scintillator, and dosimetric quantities delivered to neutron surveymeters were determined from these measurement results.

고리원자력 4호기 감시시편 X에 대한 선량분석

  • 문복자;김형헌;김용일
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05a
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    • pp.125-130
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    • 1996
  • 최근 고리원자력 4호기 압력용기에 대한 제 3차 감시시험$^{(1)}$ 이 수행되었고 그 과정 중 측정된 시편에서의 반응률을 근거로 선량분석을 수행하였다. ENDF/B-VI를 근거로 만들어진BUGLE93$^{(2)}$ 라이브러리를 사용하여 각분할코드인 DORT version 2.7.3$^{(3)}$ 를 이용한 forward 및 adjoint 수송 계산 결과와 측정된 반응률을 결합하여 고리 4호기 원자로의 감시시편 X를 대상으로 1 MeV이상의 중성자속, 0.1 MeV 이상의 중성자속 및 dpa(displacement per atom)를 계산하여 측정치와 계산치를 비교하였다.

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Skin Radioprotector (Diethone) Modifying Dermal Response of Radiation on Rats (방사선 보호제(Diethone)의 랫드 피부반응에 대한 수식작용)

  • Hong, Seong-Eon;Urahashi, Shingo;Kamata, Rikisaburo
    • Radiation Oncology Journal
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    • v.7 no.1
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    • pp.15-22
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    • 1989
  • Investigations were carried out into the time-and dose-related changes in acute skin reaction following graded single dose (20,30 and 40 Gy) of x-ray irradiation in Wistar rats, in order to evaluate the radioprotective effect of Diethon on skin. For the duration of skin response over 1. 5 score in dose of 40 Gy, the Diethone group of 24.7 days was significantly different (p<0.02) from that of control (29.8 days) and vaseline (29.2 days) groups, it was $17.1\%$ diminution of skin response period compared with that of control group. By the averaging daily scores for 10 days during peak skin reaction the mean scores were obtained. Mean score of Diethone group $(2.43\pm0.22)$ was significantly different (p<0.01) from that of control $(2.91\pm0.23)$ and vaseline $(2.81\pm0.18)$ groups of 40Gy dose. By iso-effect dose obtained at level of 2.5 score the dose reduction factor (DRF) was 1.41 which reduced radiation dose of $41\%$ by radioprotective effect of Diethone. From this experimental data, it may be possible to give higer radiation dose to large and/or radioresistant tumor mass rather than conventional treatment doses for improving therapeutic ratio by using topical application of skin radioprotector.

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Chromosomal Aberrations Induced by in Vitro Irradiation of $^{131}I$ ($^{131}I$의 체외 방사선조사에 의한 염색체이상)

  • Kim, Eun-Sil;Kim, Myung-Seon;Seo, Doo-Seon;Jeong, Nae-In;Rho, Seung-Ik;Lee, Jae-Yong;Kim, Chong-Soon;Han, Seung-Soo;Kim, Hee-Geun;Kang, Duck-Won;Song, Myung-Jae
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.1
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    • pp.133-140
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    • 1994
  • Recently, there are many considerations and studies on biological effects of radiations in radiation workers, as well as in accidentally or therapeutically irradiated persons. The most practical and reliable method of dosimetry for radiation accidents is the scoring of gross chromosomal aberrations in human lymphocytes (Ydr) as a biological dosimetry. By the way, although usual doses of $^{131}I$ administered therapeutically for thyroid cancer are ranging from 100 mCi to 200 mCi, there are differences of absorbed doses and Ydr, ranging from 0.004 to 0.04, on equally administered $^{131}I$ due to variations in metabolic characteristics, stage of tumors and physical status of subjects. In this study, We exert to obtain the dose-response relationships of $^{131}I$, as a good guide to evaluating acute effects of accidental irradiations and radiation induced leukemia or solid tumor, by in vitro induction of chromosomal aberrations. we studied the relationship between radiation dose (D) and the frequency of chromosomal aberrations (Ydr) obserbed in peripheral lymphocytes that were irradiated in vitro with $^{131}I$ at doses ranging from 0.05 to 6.00 Gy. By scoring cells with unstable chromosomal aberrations (dicentric chromosomes and ring chromosomes) we obtained this linear-quadratic dose response equation Ydr=0.064351 $D^2$-0.13143 D+0.045684 This dose-response relationship may be useful for evaluating acute and chronic $^{131}I$ induced biological effects.

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Morphological Changes of Mouse Ovary by X-Ray Irradiation (방사선 조사선량에 따른 생쥐 난소의 형태학적 변화)

  • Yoon, Chul-Ho;Choi, Jong-Woon;Yoon, Surk-Hwan
    • Journal of Radiation Protection and Research
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    • v.32 no.4
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    • pp.140-156
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    • 2007
  • This research was performed to investigate the morphological changes of folliculus ovary according to the radiation dose. The whole body radiation of 200 cGy, 400 cGy, and 600 cGy was given to the each groups of 5 months-aged female mouse. Various staining methods used in this research are: Hematosylin-Eosin method, and immunohistochemistrical methods using BrdU, TUNEL, p53, p21, PCNA and inhibin. The minute structural changes of folliculus ovary were observed through an electron microscope with high magnification. The morphological changes of growing folliculus ovary became distinct as the dose of X-rays increased. Especially, the nuclei of granular cells showed manifest condensation and the changes of the transparent zone were distinct. As a result of histochemical reaction according to Masson's trichrome method and reticular fiber method, the changed granular cells, the deformed basilar membrane of folliculus ovary and the abnormal arrangement of the reticular fiber were observed. In the reaction of BrdU, the granular cells of normal folliculus ovary with positive reaction rapidly decreased according to the increase of the dose of X-rays. In TUNEL study, granular cells showing positive reaction in retarded folliculus ovary were expanded to growing folliculus ovary and primordial folliculus ovary according to the increase of the dose of X-rays. In case of 600 cGy of X-rays, oocyte underwent apoptosis. In p53 immunohistochemistry, p53 manifested to be stronger as the dose of X-rays increased. p53 reactivity was manifested distinctively in all cells comprising folliculus ovary following irradiation of 600 cGy. p21 was manifested in granular cells of folliculus ovary and showed very positive reaction around follicular antrum according to the increase of the dose of X-rays. In PCNA, positive reaction was manifested in growing folliculus ovary, mature folliculus ovary and primordial folliculus ovary, but the extent of the reaction decreased as the dose of the X-rays decreased. The finding that the reaction of granular cells around folliculus ovary was stronger than that near follicular membrane indicates that what was damaged first by X-ray was the cells near folliculus ovary and follicular antrum. The reactivity of $inhibin-{\alpha}$ showed difference according to the growing stage of folliculus ovary: $inhibin-{\alpha}$ showed the most strong reaction in mature folliculus ovary with follicular antrum. There was strong reaction in granular cells around follicular membrane but $inhibin-{\alpha}$ did not occur at all in theca cells comprising follicular membrane. $Inhibin-{\alpha}$ in ovary tissue exposed to 400 cGy of X-rays was manifested more strongly than in ovary tissue exposed to 600 cGy of X-rays, which was related to the phenomenon that granular cells of mature folliculus ovary underwent necrosis or apoptosis increasingly due to X-rays. In an electron microscope with high magnification, nuclei and protoplasm of granular cells in growing folliculus ovary abruptly underwent minute structural changes according to the increase of dose of X-rays. Cell residue, by-product of cell decease, neutrophil and macrophage around follicular antrum were observed. The minute structural changes in granular cells showed typical characteristics of apoptosis: the increase of electronic density due to nuclear condensation, fragmentation of nuclei and atrophy of protoplasm. Necrosis of cells was identified but it was not so remarkable. Macrophage with apoptotic bodies was scattered. Proportional to the radiation dose, we found that the generation of heterogeneous substance of normal ovary texture's follicular fluid, the emergence of dyeing characteristic in the basilar membrane of folicle, the generation of apoptosis, and the transformation of macrophages, etc. From this results, we can infer the possible radiation hazard on the ovary of cervix cancer patient with radiation therapy.

저선량 방사선 영향과 발현암의 인과성 문제

  • Lee, Jae-Gi
    • Radioisotope journal
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    • v.15 no.3
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    • pp.78-92
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    • 2000
  • 낮은 선량의 방사선피폭으로 인한 건강 위해의 여부에 대하여 과학적 현황을 고찰하였다. 선량과 영향 사이에 문턱 없는 선형비례 모델(LN-T모델)에 대해 역학적, 수학적, 방사선생물학적 측면의 긍정적 논리와 호메시스, 적응반응, 통계적 관점의 비판적 논거를 대비하여 평가하였다. 방사선 피폭이력자에게 발현한 확률적 영향 특히 백혈병을 포함한 암에 대해 그 질환의 방사선 인과성 판단에 대한 애로와 접근 방향을 논의하였다. 객관적인 평가 지표의 하나로 기인확률(PC)을 적용하되 근로자에 대한 제도적 배려 등 고려할 사항을 논의하였다.

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