• Proceedings of the Korean Nuclear Society Conference
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• 1996.05a
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• pp.269-274
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• 1996

월성원자력발전소 2호기와 같은 CANDU 6형 원자로의 반응도제어기구 설치대에는 여러 반응도제어기구가 삽입되기때문에 원자로심으로부터의 방사선흐름현상으로 인한 방사선피폭이 예상될 수 있는 위치이다. 좁고 긴 반응도제어기구 도관에서의 방사선 흐름으로 인한 반응도제어기구 설치대에서의 방사선량을 예측하기 위해 몬테 칼로 MCNP 코드를 1차원 각분할법 코드인 ANISN과 연계하여 사용하였다. 월성원자력2호기의 상단차폐해석을 위한 ANISN 계산, 도관의 방사선흐름을 평가하기 위한 MCNP 계산, 그리고 반응도제어기구 설치대에서의 방사선량율 평가를 위한 MCNP 계산등 3단계 계산 기법의 적응이 시도되었다.

• Progress in Medical Physics
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• v.21 no.1
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• pp.1-8
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• 2010

In this study, we evaluated the dose response of MAGAT (Methacrylic Acid Gelatin gel and THPC) normoxic polymer gel dosimeters based on the X-ray CT scanner. To perform this study, we determined the proper ratio of the gel composition and acquired X-ray scan parameters. MAGAT gel dosimeters were manufactured using MAA (MethacrylicAcid) and gelatin of various concentration, irradiated up to 20 Gy. We obtained the 20 CT images from the irradiated gel dosimeters by using on a Phillips Brilliance Big Bore CT scanner with the various scan parameters. This CT images were used to determine the $N_{CT}$-dose response, dose sensitivity and dose resolution As an amount of MAA and gelatin were increase, the slope and intercept were increase in each MAGAT gel dosimeter with various concentration of the $N_{CT}$-dose response curve. The dose sensitivity was $0.38{\pm}0.08$ to $0.859{\pm}0.1$ and increased were amount of the MAA was increased or the gelatin was decreased. However, the change of gelatin concentration was very small compare to MAA. The Dose resolution ($D_{\Delta}^{95%}$) varies considerably from 2.6 to 6 Gy, dependent on dose resolution and CT image noise. The slope and dose sensitivity was almost ident verywith the variation of the tube voltage, tube current and slice thickness in the dose response curve, but the noise (standard deviation of averamalg CT number) was decreased when the tube voltage, tube current and slice thickness are increase. The optimal MAGAT polymer gel dosimeter based on the CT were evaluated to determine the CT imaging scan parameters of the maximum tube voltage, tube current and slice thickness (commonly used in clinical) using the composition ratio of a 9% MAA, 8% gelatin and 83% water. This study could get proper composition ratio and scan parameter evaluating dose response of MAGAT normoxic polymer gel dosimeter using CT scanner.

• Applied Chemistry for Engineering
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• v.7 no.5
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• pp.946-953
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• 1996

The effect of absorbed dose, dose rate, cationic salts and solvent on the grafting yield was evaluated when acrylic acid was grafted onto polypropylene fabric by simultaneous irradiation process. Low dose rate when irradiated with the same absorbed dose led to a high grafting yield. On the other hand, the grafting yield increased with dose rate in case the total irradiation times is equal, and the initial rate of grafting was found to be proportional to be 0.74 power of dose rate. $FeSO_4{\cdot}7H_2O$ was found to be the most effective additive for high grafting yield, while inhibiting homopolymer formation. It was impossible to induce radiation grafting without the addition of the certain amount of salt, but the grafting yield decreased with increasing metallic salt.

• 대한방사선방어학회:학술대회논문집
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• 2009.04a
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• pp.296-297
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• 2009

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2005.10a
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• pp.150-152
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• 2005

환경친화적 기술로 알려진 방사선조사기술(RT: Radiation Technology)을 이용하여 돈피 유래 올리고펩타이드를 제조하고자 하였다. 생 박 돈피를 hammer mill과 chopper를 이용하여 조분쇄한 후 $-20^{\circ}C$ 아세톤으로 탈지하였고, ${\gamma}$-ray irradiator를 이용하여 0, 20, 40, 60, 100, 150, 200, 250, 300 kGy의 총 흡수량을 얻도록 탈지돈피에 방사선조사를 실시하였다. 방사선조사에 의한 탈지돈피의 pH 변화는 0${\sim}$100 kGy 조사선량에서는 미비했으나, 150 kGy 이상에서는 소폭 증가하였다. 탈지돈피의 단백질 함량 중 콜라겐 함량은 93% 이었으며 방사선조사된 돈피콜라겐을 효소처리하면 효소반응 시간이 길어질수록 약 24 kDa 범위에서 밴드가 확인되었고, 100 kGy 이상의 고선량에서는 효소반응 2시간 이후 10% polyacrylamide 전기영동 겔의 최 하단에 머무는 분자량의 펩타이드가 다량 관찰되었다. 용해도 변화는 20${\sim}$60 kGy의 선량에서는 효소반응 시간이 길어질수록(1시간${\sim}$4시간) 최대 65${\sim}$80%의 용해도 증가를 보였고, 반면에 100 kGy 이상에서는 효소반응 시간에 관계없이 80% 이상, 300 kGy에서는 90% 이상의 용해도를 보여주려다. 점도와 탁도는 100 kGy 이상의 고선량에서 짧은 효소반응 시간(1시간)에 급격히 감소하였다. 가수 분해물(300 kGy)을 gel permeation chromatography한 결과 분자량 9,000 Da의 주 피크가 검출되었다.

• Journal of Radiation Protection and Research
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• v.20 no.2
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• pp.97-102
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• 1995

Adaptive response induced by low dose ${\gamma}-ray$ irradiation in human peripheral lymphocytes was examimed. Human lymphocytes were exposured to low dose of ${\gamma}-ray$ (priming dose, 0.01Gy) followed by high dose (challenging dose, 1.5Gy) after various time intervals (4, 7, 20 hours). Frequencies of micronuclei were enumerated in both primed and unprimed groups. Maximum reduction in frequency of micronuclei was observed when challenging dose irradiation was followed by priming dose after 4hr incubation period. When challenging doses were irradiated 7 or 20hr after priming dose, frequencies of micronuclei were reduced slighty. However, these reduction were not statistically significant. In this study, human peripheral lymphocytes were irradiated at Go phase and they showed adaptive response induced by low dose radiation. Since micronucleus assay is relatively simpler and faster than other methods, it may be a good tool for evaluating radiation-induced adaptive responses.

• Proceedings of the Korean Nuclear Society Conference
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• 1995.05b
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• pp.799-804
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• 1995

DUPIC 핵연료의 사용전 그리고 사용후 조건에서 방사선량을 분석하였다. 사용후 핵연료로 35,000 MWD/MTU의 표준 연소도와 50,000 MWD/MTU의 고 연소도을 사용하였고 선량률을 계산하기 위해 CANDU의 핵연료 집합체을 균등 혼합체로 가정 하였다. 조사선량율은 건식가공을 거치지 않았을 때 매우 높은 수치를 나타내었지만 건식가공을 한 후에는 많이 감소하개 됨 을 볼 수 있었다. 특히 Cs에 민감한 반응을 보였고 Cs을 100% 제거하였을 경우 전체 선량율이 약 90%가 줄어드는 결과를 얻었다. 아울러 사용후 DUPIC핵연료의 선량율도 건식가공 방법에 많은 영향을 받고 있다.

• 대한방사선방어학회:학술대회논문집
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• 2011.11a
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• pp.140-141
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• 2011

• Radiation Oncology Journal
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• v.15 no.1
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• pp.65-69
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• 1997

Purpose : To obtain the actual dose distribution from measured data by doconvolution method using the measured ion chamber response function. Materials and Methods : The chamber response functions for 2 ionization chambers (diameter 5mm, 6.4mm) were measured. and dose Profiles were measured for $10{\times}20cm^2$ field size using two different detectors. The deconvolution of chamber response function from the measured data were performed for these Profiles. The same procedures were repeated for 4MV, 6MV and 1 SMV photon energies. Results : Different dose Profiles were obtained for the same field with the chambers which have the different response functions. Nearly the same results could be obtained with deconvolution for the profiles from various detectors. Conclusion : The effect of the chamber response function can be extracted by deconvolution method. Deconvolved dose profile using various ionization chambers gave better dose distributions. Technical improvements are needed for practical application.

• Radiation Oncology Journal
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• v.29 no.2
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• pp.63-70
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• 2011

Purpose: To evaluate the extent of pain response and objective response to palliative radiotherapy (RT) for bone metastases from hepatocellular carcinoma according to RT dose. Materials and Methods: From January 2007 to June 2010, palliative RT was conducted for 103 patients (223 sites) with bone metastases from hepatocellular carcinoma. Treatment sites were divided into the high RT dose and low RT dose groups by biologically effective dose (BED) of 39 $Gy_{10}$. Pain responses were evaluated using the numeric rating scale. Pain scores before and after RT were compared and categorized into 'Decreased', 'No change' and 'Increased'. Radiological objective responses were categorized into complete response, partial response, stable disease and progression using modified RECIST (Response Evaluation Criteria In Solid Tumors) criteria; the factors predicting patients' survival were analyzed. Results: The median follow-up period was 6 months (range, 0 to 46 months), and the radiologic responses existed in 67 RT sites (66.3%) and 44 sites (89.8%) in the high and low RT dose group, respectively. A dose-response relationship was found in relation to RT dose (p=0.02). Pain responses were 75% and 65% in the high and low RT dose groups, respectively. However, no statistical difference in pain response was found between the two groups (p=0.24). There were no differences in the toxicity profiles between the high and low RT dose groups. Median survival from the time of bone metastases diagnosis was 11 months (range, 0 to 46 months). The Child-Pugh classification at the time of palliative RT was the only significant predictive factor for patient survival after RT. Median survival time was 14 months under Child-Pugh A and 2 months under Child-Pugh B and C. Conclusion: The rate of radiologic objective response was higher in the high RT dose group. Palliative AT with a high dose would provide an improvement in patient quality of life through enhanced tumor response, especially in patients with proper liver function.