• Herbal Formula Science
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• v.11 no.1
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• pp.129-149
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• 2003

Liver is an important target of the toxicity of drugs, xenobiotics and oxidative stress. Acetaminophen pverdose causes acute liver injury in both humans and animals. This study was performed to observe the effect of sachunwhan and its component groups on recovery of hepatoxicity in acetaminophen treated rats. The experimental group was divided into 4 groups: sachungwhan(SC), samultang group(SC-1: 當歸, 川芎), chungyul group(SC-2: 龍膽草, 大黃, 梔子), and haepyo group(SC-3:羌活, 防風). Under the same condition Normal group was fed basal diet and water; Control group was injected acetaminophen and fed basal diet for 2 weeks; Experimental groups were injected acetaminophen and fed each extracts for 2 weeks respectively. The results were obtained as follows: 1. In the study on antioxidative defense system in vivo, SC reduced the amount of lipid peroxide in both serum and liver and showed activity on antioxidative enzymes such as catalase, glutathion. Other groups had effect only on glutathion. 2. In the study on hepatotoxicity(GOT, GPT, ${\gamma}$-GTP, ALP, LDH, Bilirubin), SC had a significant effect on recovery of hepatoxicity in acetaminophen treated rats. Other groups had no effect except SC-1 having effect on ${\gamma}$-GTP. As results shown, only Sachungwhan(SC) has significant effects on recovery of hepatoxicity and antioxidative defense system in vivo. These results suggest that Sachungwhan(SC) made antioxidative defense system active and it seemed to be very important to its effect on recovery of hepatoxicity. In the other hand, Component groups had no effect on recoverv of hepatoxicity and antioxidative defense system in vivo. This was thought that component drugs' cooperative synergy effect would be important to Sachungwhan(SC)'s effects mentioned in this paper.

• Journal of Society of Preventive Korean Medicine
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• v.9 no.1
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• pp.37-48
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• 2005

Subjects in this study comprised of general public (907), high school students (772), individuals associated with Oriental medicine (660), and 60 majoring in western medicine, totalling 2,413 individuals. Survey was conducted on the necessity of establishing Oriental medicine school at the national university level and the following result were obtained: - 78.3% (1847 individuals) were in favor of establishing Oriental medicine school at the national university level. - For the validity of establishment, responders expressed opinions of standard and virtuous education, higher quality education, standardized practice, research on difficult to cure diseases, and obtaining competitiveness in the world market. - One to three schools were considered as an appropriate number of schools with less than 80 students per class, Class size may be adjusted from existing schools (52.5% favored decrease in size) and (46.3% favored increase in size). - Educational and research facilities must be accopanied with schools of Oriental medicine as well as clinical training facilities, herbal pharmaceutical research centers, and fundamental medical centers. - Many favored 6 year curriculum as the most appropriate system and the school of Oriental medicine should be established within the university. Based on the information gathered in this survey, we may recognize the limitations of Oriental medicine schools at the private institutional level and support the establishment of Oriental medicine schools at th national university level. This establishment may play as a steeping stone for advancement in education, standardization of research and treatment, and commercialization of Oriental medicine of benefit the general public.

• Korean Journal of Head & Neck Oncology
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• v.27 no.1
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• pp.12-16
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• 2011

Background and Objectives : The pectoralis major myocutaneous flap(PMMCF) has been considered to be the "workhorse" of pedicled flaps in head and neck reconstruction. Even with the worldwide use of free flaps, the PMMCF is still considered the mainstay in head and neck reconstruction. The aim of the study is to evaluate the application and reliability of the PMMCF in selected cases of head and neck complication. Materials and Methods : We conducted a retrospective review of 14 patients who underwent the surgical reconstruction using the PMMCF due to the complications after head and neck ablative surgery between 1997 and 2007. Outcome measures included the indications of PMMCF, complications and post-operative functional result. Results : PMMCFs were used to reconstruct defects in the following series; wound dehiscence(7 patients), flap failure(4 patients), pharyngocutaneous fistula(3 patients). Flap survival was 100 percent and mean flap size was $67.2cm^2$. Five patients had complications such as pharyngocutaneous fistula, marginal necrosis, carotid blowout. Conclusions : The PMMCF is a safe and convenient method for reconstruction of the surgical complications after resection of advanced tumors and can be still used as a salvage procedure after free flaps failure.

• Korean Journal of Head & Neck Oncology
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• v.30 no.1
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• pp.10-14
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• 2014

목 적 CO2 가스 삽입 없이 내시경 보조 갑상선 절제술, 특히 액와 절개를 이용하는 경우의 대부분은 기구 사용을 용이하게 하기 위하여 흉부 또는 유륜에 절개를 넣어 시행하는 것이 대부분이다. 본 연구는 후이개 절개를 통하여 추가적 절개 없이 내시경을 이용한 갑상선 절제술 및 중심 임파선 절제술이 가능한지의 여부를 사체연구를 통하여 확인해 보고자 한다. 방 법 사체 이용 해부 및 수술 후이개 내시경 보조 갑상선 절제술이 가능한지의 확인은 수술 시야 및 접근성, 수술 완성도, 그리고 주요 구조물의 보존 여부인 3가지 항목으로 평가하였다. 결 과 수술 시야는 기구를 다루고 수술을 하기에 충분하였으며, 추가 절개 없이 수술을 완성할 수 있었다. 절제된 갑상선 조직의 피막은 손상되지 않았으며, 잔존 갑상선 조직이 없음을 수술 부위를 통하여 확인하여, 수술의 완성도 여부를 평가할 수 있었다. 모든 사체에서 되돌이 후두신경 및 상 또는 하부갑상선의 보존을 확인하였으며, 주변 구조물들의 손상이 없음을 확인하였다. 결 론 로봇이 아닌 후이개 절개를 이용한 내시경 보조 갑상선 절제술은 시행 가능한 접근법 및 수술방법이라 사료된다.

• Informatization Policy
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• v.20 no.2
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• pp.73-90
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• 2013

Rational debate and public conversation in the public sphere of social network are crucial conditions for realizing deliberative democracy. However, negative communication can occur online more frequently than in the real space, and mutually hostile messages are appearing. In the electoral process, citizens combining for particular candidates have made personal attacks against, abused and slandered the opposing candidates. Then, how and to what degree has the flaming behavior been appearing in the elections? Are there influencers to propagate the flaming behavior? And how flaming are these influencers, compared to internet users? This research focuses on the flaming behavior which occurred during the reelection for Seoul Mayor, in order to diagnose the role of social network as an online public sphere. This study analyzes the spreading degree of flaming messages depending on each issue, and the differences of messages between influencers and normal users. There was frequent flaming behaviors to distribute biased information which criticized, laughed at and maliciously attacked individual candidates. Moreover, influencers who advanced leading opinions, displayed a higher flaming degree than normal users.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.2
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• pp.261-271
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• 2009

Due to the recent rise of a need for 3 dimensional geospatial information on urban areas, general interest in aerial multi-view cameras has been on an increase. The conventional geospatial information system depends solely upon vertical images, while the multi-view camera is capable of taking both vertical and oblique images taken from multiple directions, thus making it easier for the user to interpret the object. Through our research we developed a prototype of a multi-view camera system that includes a camera system, GPS/INS, a flight management system, and a control system. We also studied and experimented with the camera viewing angles, the synchronization of image capture, the exposure delay, the data storage that must be considered for the development of the multi-view camera system.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.4C
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• pp.397-405
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• 2003

In this paper, we propose an efficient motion estimation algorithm which can reduce computational complexity by using characteristics of wavelet coefficient in each subband while keeping about the same image quality as in using MRME(multiresolution motion estimation). In general, because of the high similarity between consecutive frames, we first decide whether the motion exists or not by just comparing MAD(mean absolute difference) between blocks with threshold in the lowest subbands of consecutive two frames. If it turns out that there is no motion in the lowest subband, we can also decide no motion exists in the higher subband. This is due to the characteristics of wavelet transform. Conversely, if we find any motion in the lowest subband, we can reduce computational complexity by estimating high subband motion vectors selectively according to the amount of computational complexity by estimating high subband motion vectors selectively according to the amount of energy in that subband. Experimental results are shown that algorithm suggested in this paper maintains about the same PSNR as MRME. However, the processing time was reduced about 30-50% compared with the MRME.

• Journal of the Korean association of regional geographers
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• v.20 no.3
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• pp.315-333
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• 2014

The study was carried out to analyze election regionalism and to find out the spatial pattern of party support drawn in the 18th general election. Strongly biased pattern found to be caused by party strategies and voting behaviour preferring for the local party. Each party employed the strategies such as tactical and nepotic nomination, regional development pledges, and local instigation of regionalism. In consciousness survey done by the National Election Commission, primarily people tend to choose the representative by his(her) party and secondly, they consider their carrier and occupation. They vote for the same party in the local district and proportional representation. While election regionalism strongly found in voting behaviour of each party's main strongholds based on spatial pattern of major party support, voters of Seoul and Chungbuk tend to vote for their interests due to regional development pledges such as 'Newtown' Development and 'Multifunctional Administrative City' construction.

• Ecology and Resilient Infrastructure
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• v.3 no.4
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• pp.307-314
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• 2016

River restoration has recently been performed not only for the improvement of the artificial parts in the past but also for the restoration of abandoned river reaches which were blocked and isolated. For the restoration of abandoned river reaches, it is important to recover the hydraulic and ecological connectivity in the isolated space by longitudinal structures like levees. But because the assessment tools to determine whether the river restoration is performed properly are so rare at present, we aim to provide a tool for assessing ecological connectivity in a target river in this study. In the first step, one-dimensional numerical model for rainfall-runoff and channel routing was developed and then applied to the watershed of the Cheongmi Stream. In this step, a numerical model was developed to assess the restoration of connectivity. The model consists of two parts: one part is to convert the results of one-dimensional channel routing into two-dimensional spatial distribution. The other is to calculate the habitat suitability index according to time steps by using two-dimensional hydraulic features. The model was applied to a restoration area of the Cheongmi Stream. The advantage of this study is that two-dimensional hydraulic analysis can be easily obtained from one-dimensional hydraulic analysis without a complex and time-consuming two-dimensional analysis. HHS (Hydraulic Habitat Suitablility) by sections of target reaches and target species can be easily obtained using the results of this study.

• The Journal of Dong Guk Oriental Medicine
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• v.7 no.2
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• pp.141-148
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• 1999

A simple and rapid FoLT(formamide low temperature)-PCR, whereby human genomic DNA from blood can be amplified without DNA preparative stps, is described using human insulin genes. By applicatin of FoLT-PCR in human insulin genes, intragenic polymorphism in non-coding regions of the human insulin gene was shown after amplification and analysis by restriction enzyme digestion. All nucleotide sequences were the same as the reported, and four necleotides, at 4 different positions were polymorphic, and polymorphic alleles ${\alpha}4$, ${\alpha}5$, ${\alpha}6$, and ${\beta}2$ were identified. The new alleles were originated from homologous recombination between the ${\alpha}1$ and ${\beta}1$ alleles, and the alleles were founded in heterozygotes only. Although allele ${\alpha}1$ was dominant, the new alleles and ${\beta}1$ were recessive. From the results, it was suggested that the new method of FoLT-PCR was highly applicable in genetic variation analysis.