• Title/Summary/Keyword: 생체적합도

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ECG Filtering using Empirical Mode Decomposition Method (EMD 방법을 이용한 ECG 신호 필터링)

  • Lee, Geum-Boon;Cho, Beom-Joon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.12
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    • pp.2671-2676
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    • 2009
  • Empirical mode decomposition (EMD) is new time-frequency analysis method to decompose the signal adaptively and efficiently. The key idea of EMD is to decompose the signal into a set of functions defined by the signal itself, named Intrinsic Mode Functions (IMFs), which preserve the inherent properties of the original signal. Since the decomposition is based on the local time scale of the signal, it is not only applicable to nonlinear and non-stationary processes but also useful in biomedical signals like electrocardiogram (ECG). Traditional low-pass filter uses fourier transform to analysis signal in frequency domain, but EMD is filtered to maintain signal properties in time domain. This paper performed signal decomposition and filtering for noisy ECGs using EMD method. The proposed method is presented and compared with traditional low-pass filter by two performance indices. Our results show effectiveness for enhancement of the noisy ECG waveforms.

User Authentication Mechanism using Smartphone (스마트폰을 이용한 사용자 인증 메커니즘)

  • Jeong, Pil-seong;Cho, Yang-hyun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.2
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    • pp.301-308
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    • 2017
  • With the popularization of smart phones and the development of the Internet, many people use smart phones to conduct identity verification procedures. smart phones are easier and faster to authenticate than personal desktop computers. However, as Internet hacking technology and malicious code distribution technology rapidly evolve and attack types become more diverse, authentication methods suitable for mobile environment are required. As authentication methods, there are methods such as possessive-based authentication, knowledge-based authentication, biometric-based authentication, pattern-based authentication, and multi-element authentication. In this paper, we propose a user authentication mechanism that uses collected information as authentication factor using smart phone. Using the proposed authentication mechanism, it is possible to use the smart phone information and environment information of the user as a hidden authentication factor, so that the authentication process can be performed without being exposed to others. We implemented the user authentication system using the proposed authentication mechanism and evaluated the effectiveness based on applicability, convenience, and security.

Fingerprint Image Quality Analysis for Knowledge-based Image Enhancement (지식기반 영상개선을 위한 지문영상의 품질분석)

  • 윤은경;조성배
    • Journal of KIISE:Software and Applications
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    • v.31 no.7
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    • pp.911-921
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    • 2004
  • Accurate minutiae extraction from input fingerprint images is one of the critical modules in robust automatic fingerprint identification system. However, the performance of a minutiae extraction is heavily dependent on the quality of the input fingerprint images. If the preprocessing is performed according to the fingerprint image characteristics in the image enhancement step, the system performance will be more robust. In this paper, we propose a knowledge-based preprocessing method, which extracts S features (the mean and variance of gray values, block directional difference, orientation change level, and ridge-valley thickness ratio) from the fingerprint images and analyzes image quality with Ward's clustering algorithm, and enhances the images with respect to oily/neutral/dry characteristics. Experimental results using NIST DB 4 and Inha University DB show that clustering algorithm distinguishes the image Quality characteristics well. In addition, the performance of the proposed method is assessed using quality index and block directional difference. The results indicate that the proposed method improves both the quality index and block directional difference.

BIOCOMPATIBILITY OF RETROGRADE FILLING MATERIALS (역충전재의 생체적합성에 관한 연구)

  • Im, Mi-Kyung
    • Restorative Dentistry and Endodontics
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    • v.25 no.1
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    • pp.63-70
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    • 2000
  • The properties of ideal retrograde filling materials include the ability to seal the root canal system in three dimensions and well tolerated by periradicular tissues. Biocompatibility testing has been done mainly with cytotoxicity tests using cell culture. Little attention has been paid to the potential adverse influence on the inflammatory and immune reaction in the periapical tissue. The purpose of this study was to investigate the effects of retrograde filling materials on human mononuclear cells in vitro. Freshly mixed and set specimens from six materials (Z100, Tetric Ceram, Fuji II, Fuji II LC, F2000, Compoglass Flow, and ZOE) were eluated with cell culture medium for 24 hours. Cytotoxic effects of these extracts were evaluated by determining cell viability and enzyme activity using MTT and lactate dehydrogenase (LD). The production of inflammatoy bone resorptive cytokine, TNF-${\alpha}$ was measured from human peripheral blood mononuclear cells (PBMC) exposed to the extracts by means of Endogen Human TNF-${\alpha}$ ELISA kit (Wobrun, MA, U.S.A.). Eluates and diluted (1 : 10) eluates with cell culture medium from freshly mixed Fuji IT had cytotoxic effects on mononuclear cells using MTT and LD. However, eluates from set Fuji II were not cytotoxic. Eluates form set ZOE exhibited cytotoxicity with LD test. TNF-${\alpha}$ levels were high in eluates from freshly mixed Fuji II and Z100. Diluted eluates from freshly mixed Z100 and F2000 stimulated the production of TNF-${\alpha}$. However, there were no significant difference in TNF-${\alpha}$ levels compared to controls. These results indicate that some materials could possibly stimulate bone resorption in the periapical tissue by means of the production of bone resorptive cytokine.

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Study on Recycling of Waste Rubbers as Medium Components for Hydroponic Culture of Rose (장미 양액재배 배지의 구성요소로서 폐고무의 재활용에 관한 연구)

  • 김진국;이형규;정병용;황승재
    • Resources Recycling
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    • v.9 no.3
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    • pp.46-53
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    • 2000
  • Recently, the efficient disposal of the waste rubber is necessary due to increasing amount of the waste rubbers. In this paper, method of recycling waste rubbers as components of medium for hydroponic rose culture was suggested. We investigated growth of rose, and macro- and micro-elements, pH and EC of the media amended with waste rubber, In the beginning of culture, stress symptoms such as thin brittle stem and incipient wilting were observed, but they disappeared in a few weeks. Concentration of $Zn^{2+}$ in media at flowering increased in proportion to contents of waste tire in the media. pH of media at flowering were in the range of 5.70 to 6.35. Rose growth in all media, except in wasterock wool mixed with EPDM powder at 9:3 ratio, was normal and equivalent to the control in terms of stem length, number of stems harvested and fresh weight.

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A Review of biomechanical research for Footwear Outsole Stud development in Soccer (축구화 겉창 스터드 개발에 있어서 생체역학적 연구의 고찰)

  • Park, Seung-Bum;Seo, Kuk-Woong;Kim, Yong-Jae;Lee, Joong-Sook
    • Korean Journal of Applied Biomechanics
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    • v.13 no.1
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    • pp.205-221
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    • 2003
  • 본 연구는 축구화 겉창의 스터드개발시 운동역학적 연구가 스터드개발에 어떻게 영향을 끼치었는가를 국외 선행연구문헌을 고찰함으로서 그 과정을 발견하는데 그 목적을 두었다. 지난 70년간 축구화 스터드가 연구개발되는 과정에서 압력분포측정 실험 및 기타 상해유발요인을 분석함으로서 스터드의 형태을 변화시키는 과정에 있어서 축구장 바닥과 축구화 겉창과의 마찰력이 중요한 변수로 작용하였다. 징이 선수들의 미끄럼을 방지하고 순발력을 향상시켜 경기력 향상에 결정적인 도움을 준 것이다. 이후 징박힌 축구화가 보편화하면서 선수들은 공격수냐 수비수냐 또는 잔디 상태에 따라 징의 개수와 길이가 다른 축구화를 신게 되었는데, 그라운드 컨디션에 따라 신발이 개발되었다. 축구화는 징의 종류에 따라 길고 푹신한 잔디($5{\sim}7$월 잔디)에 신는 50(soft ground)형, 짧고 단단한 잔디(가을철 잔디)에 적합한 FG(firm ground)형, 인조잔디나 아주 짧은 잔디에 좋은 터프(Turf)형, 맨땅에 쓰는 HG(hard ground)형으로 대별되는데, SG형은 15mm가 넘는 마그네슘 징을 6개 박는데 순발력과 파워를 극대화하기 때문에 수비수에 어울리는 스타일이다. 짧은 플리우레탄 징 12개를 다는 FG형은 넓은 그라운드 접촉면을 이루면서도 잔디에 깊게 박히지 않아 유연성을 필요로 하는 공격수와 미드필더들에게 애용된다. 그라운드 상황이 좋지 않은 곳에서 뛰는 국내 고교, 대학 선수들은 12개의 징이 달린 축구화를 선호한다. 스터드가 많을 수록 그라운드에 닿는 면적이 넓어 안정감도 있고 발목이 꺾이는 현상을 줄여주기 때문이다. 지금까지의 연구현황은 압력분포 및 지면반력실험을 이용한 결과치를 이용하여 새로운 타입의 축구화 스터드의 개발결과를 기존결과와 비교 분석하여 상해유발발생요인이 적은 스타일의 스터드를 선호하였다. 이에 향후 연구개발시 운동역학적 연구의 디자인 시 상해유발요인분석과 운동역학적 연구결과의 조합을 결과를 비교분석해서 국내에서도 축구화 겉창 스터드 연구개발시 경기력을 향상시키고, 상해유발요인을 감소시킬 수 있는 연구디자인이 지속되는 것이 중요하다고 사료된다.

Preparation and Properties of Biodegradable Hydrogels from Poly(2-hydroxyethyl aspartamide) and HMDI (HMDI 가교 폴리아스팔트아미드 수화젤의 제조 및 특성)

  • Kim Jeong Hoon;Sim Sang Jun;Lee Dong Hyun;Kim Dukjoon;Lee Youngkwan;Kim Ji-Heung
    • Polymer(Korea)
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    • v.29 no.5
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    • pp.518-521
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    • 2005
  • Biodegradable polymers and hydrogels have been increasingly applied in a variety of biomedical applications including current drug delivery system and tissue engineering field. ${\alpha},\;{\beta}-Poly$(N-2-hydroxyethyl-DL-aspart-amide), PHEA. is one of poly(amino acids) with hydroxyethyl pendants, which is hewn to be biodegradable and potentially biocompatible. So that, the utilization and various chemical modifications of PHEA have been attempted for useful biomedical applications. In this wort chemical gels based on PHEA were prepared by crosslinking with diisocyanate compound in DMF in the presence of catalyst. Here, the PHEA was prepared from polysuccinimde, the thermal polycondensation product of aspartic acid, via ring-opening reaction with ethanolamine. The preparation of gels and their swelling behavior, depending on the different medium and pH, were investigated. Also the morphology by SEM and simple hydrolytic degradation were observed.

Preparation and Properties of Poly(vinyl alcohol)/Chitosan Blend Films (폴리(비닐 알코올)/키토산 블렌드 필름의 제조 및 특성)

  • 정민기;김대선;최용혁;손태원;권오경;임학상
    • Polymer(Korea)
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    • v.28 no.3
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    • pp.253-262
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    • 2004
  • Poly(vinyl alcohol)(PVA)/chitosan blend films with non-toxicity, biodegradability, and biocom-patibility were prepared by solution casting. Variation of the physicochemical properties of the blend films was investigated through to several analysis methods. Examination of antibacterial properties revealed that bacterio-static ratios of all blend samples containing chitosan more than 10 wt% were greater than 99.9%. Moisture regain was increased with increasing chitosan content but the degree of swelling was decreased. Up to chitosan content 15 wt%t, the melting and crystallization temperature of blend films was increased with chitosan content. The blends containing chitosan content 10 and 15 wt% gave melting temperature 229 and 228$^{\circ}C$, respectively. However, the melting temperature was decreased if chitosan content exceeded 20 wt%. The mechanical properties of the blend films were increased with increasing chitosan content in both dry and wet states. The blend film including 15 wt% chitosan exhibited unusually high tensile strength.

Thermosensitive Sol-gel Phase Transition Behavior of Methoxy poly(ethylene glycol)-b-poly($\varepsilon$-caprolactone) Diblock Copolymers (메톡시 폴리(에틸렌 글리콜)-폴리($\varepsilon$-카프로락톤) 공중합체의 온도감응성 솔-젤 전이 거동)

  • 서광수;박종수;김문석;조선행;이해방;강길선
    • Polymer(Korea)
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    • v.28 no.4
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    • pp.344-351
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    • 2004
  • Poly(ethylene glycol)-based diblock and triblock polyester copolymers stimulating to temperature were studied as injectable biomaterials in drug delivery system because of their nontoxicity, biocompatibility and biodegradability. We synthesized the diblock copolymers consisting of methoxy poly(ethylene glycol) (MPEG) (M$_{n}$=750 g/mole) and poly($\varepsilon$-caprolactone) (PCL) by ring opening polymerization of $\varepsilon$-CL with MPEG as an initiator in the presence of HCl . Et$_2$O. The aqueous solution of synthesized diblock copolymers represented sol phase at room temperature and a sol to gel phase transition as the temperature increased from room temperature to body temperature. To confirm the in vivo gel formation, we observed the formation of gel in the mice body after injection of 20 wt% aqueous solution of each block copolymer. After 2 months, we observed the maintenance of gel without dispersion in mice. In this study, we synthesized diblock copolymers exhibiting sol-gel phase transition and confirmed the feasibility as biomaterials of injectable implantation.n.

Study on Radial Force of Helical Structure for Biodegradable Polymer Stents (생분해성 고분자 스텐트를 위한 나선헝 구조의 팽창력 연구)

  • Park, Chul-Ho;Park, Ga-Ram;Choi, Ji-Yeon;Park, Kwi-Deok;Han, Dong-Keun
    • Polymer(Korea)
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    • v.35 no.3
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    • pp.260-264
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    • 2011
  • Biodegradable polymeric stents have been issued to replace the existing non-degradable metal stents due to relatively improved biocompatibility and low side effects. Fundamentally, all the stents must possess the desired mechanism strength, especially, compression or radial force to maintain the diameters of expanded vessels. Therefore, this study suggests a helical structure and focused on the relation between the lateral compression and structural factors, Unlike a cylindrical model, the radial force of the helical model is proportional to the thickness and the length to the power of one, whereas the diameter to the power of 1.6. The function obtained from these results might provide the fundamental information to design and prepare the stem for clinical applications.