• 대한생식의학회:학술대회논문집
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• 1999.11a
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• pp.74-75
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• 1999

• The Science & Technology
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• v.30 no.6 s.337
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• pp.82-82
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• 1997

생물계에서는 기생충이 숙주의 행동과 생리를 바꾸는 현상이 많이 일어난다. 숙주의 생식에 영향을 미치는 '기생거세'라는 것이 있으니 생식소가 기생충의 칩입을 받아 생식능력을 잃거나 성전환을 하는 등 기이한 현상을 볼 수 있다.

• 대한생식의학회:학술대회논문집
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• 2001.06a
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• pp.80.2-81
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• 2001

• 월간산업보건
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• s.342
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• pp.53-57
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• 2016

• Proceedings of the Korean Nutrition Society Conference
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• 2002.05a
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• pp.105-105
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• 2002

• 대한생식의학회:학술대회논문집
• /
• 1995.12a
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• pp.23-25
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• 1995

• Development and Reproduction
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• v.7 no.1
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• pp.35-40
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• 2003

Gonadotropin releasing hormone(GnRH), which is secreted from the hypothalamus, has a pivotal role in the reproduction of mammals. Golden hamsters are seasonal breeding mammal and their sexual activity is determined by photoperiod(length of light per day). Long photoperiod(LP, $\leq$ 12.5 hours of light) maintains the reproductive activity and short photoperiod(SP, $\leq$ 12 hours of light) suppresses it. In order to investigate in detail, the sexual activity was individually examined in SP-housed male golden hamsters received a vector at three different concentrations which contains rat GnRH cDNA. The gonadal regression was significantly(P<0.05) accelerated by the highest concentrations of the vector at 8 and 10 weeks after the treatment in comparison to the other groups. In the light of pulsatile release of GnRH in maintaining reproductive activity, the vector containing GnRH cDNA might secrete the GnRH in a constant high level. These results suggest that the GnRH-containing vector might desensitize the anterior pituitary, leading to acceleration or testicular regression.

• 대한생식의학회:학술대회논문집
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• 1998.05a
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• pp.21-31
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• 1998

• 대한생식의학회:학술대회논문집
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• 1995.12a
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• pp.68.2-69
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• 1995

• Development and Reproduction
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• v.11 no.3
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• pp.219-226
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• 2007

This study was conducted to identify optimistic primordial germ cells'(PGCs) migration activity using heat activated busulfan treatment for the increasing germline chimerism. Donar PGCs viability tests of important conditions for useful germ line chimerism indicated approximately $70{\sim}80%$ viability was time dependent. Transplantation experiments of PGCs into recipient embryos after busulfun treatment, showed the treatment group having 23.5% viability. By comparison, the control group showed 4.8% viability. The 96 hour treatment group and the 118 hour treatment group of the cultured PGCs showed high migration activity. Generally, the transplantation method would consider morphological and physiological characteristics before transplantation. In the present study, the effect of busulfan on migration activity showed viability highest at 53.4% after 48-hour incubation time. However, a previous study showed the best condition for transplantation time to be prior to the 48-hour incubation period, when the chicken embryo does not yet have a developed blood vessel system. In conclusion, an important condition for the production of a transgenic chicken is that most donor PGCs migrate into the recipient embryo without any inhibitory factors. The present results suggest, perhaps by using this modified method of transplantation, it can produce a more efficient chimeric germ line, transgenic chicken.