• Title/Summary/Keyword: 생물안전

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Laboratory Biosafety Status of Researchers in Korea (국내 연구원들의 생물안전 개념에 대한 현황)

  • Kim, Dae Sik;Kim, Mi Kyung
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.1
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    • pp.71-76
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    • 2018
  • This study examined the status of the laboratory biosafety of researchers in Korea during 03 Jan 2017~25 Mar 2017. Questionnaires were given out to 500 researchers working with pathogens in the laboratory of universities and institutes. According to the results, the respondents showed a high level of awareness but not compliance on the overall biosafety rules and regulations. Regarding the Biosafety facility level, 279 (55.8%) of respondents answered "know" and 221 (44.2%) of respondents answered "no". Despite the insufficient safety equipment and biosafety plans, researchers believed that appropriate safety measures could protect the workers and that their laboratories are safe. In a study involving biosafety education, 80% of the researchers had been trained in laboratory safety and 20% had never received safety education. The need for biosafety education was 66% and the satisfaction rate of education was 46%. These results suggest that the researchers already had experience in biosafety training, but they believed that continuing education is necessary. In addition, there were opinions that the most important thing to improve the biosafety status is to strengthen the training program and education system. In conclusion, it is necessary to develop a better training system for laboratory biosafety regarding the exposure risks.

Allergenicity assessment of novel proteins expressed in genetically modified organisms (유전자변형생물체의 알레르기성 평가와 이해)

  • Lee, Sang-Gu;Oh, Seon-Woo;Park, Soo-Yun;Park, Hyoun-Min;Kim, Eun-Ha;Jin, So-Ra;Ryu, Tae-Hun
    • Journal of Plant Biotechnology
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    • v.48 no.4
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    • pp.201-206
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    • 2021
  • To ensure the safety of developing or importing genetically modified organisms (GMOs), Korea has enacted the "LMO Act." Accordingly, the safety of using GMOs as food or feed is evaluated in accordance with the concept of "substantial equivalence" proposed by OECD. The allergenicity of GMOs is assessed as a part of their safety evaluation. The methods of allergenicity assessment have been discussed by various international organizations, such as the OECD, FAO, and WHO. The main methods used for the allergenicity assessment of proteins newly expressed in GMOs include assessment of the physicochemical stability of these proteins, evaluation of their amino acid homology with existing allergenic proteins, and serum screening. In this study, we describe guidelines and related studies for the allergenicity assessment of GM crops.

Studies on the Structural Design of Biological Production Facility(2) Simple Methods for Design Load Estimation and Safety Test (생물생산시설의 구조설계에 관한 연구 (2) 설계하중 산정 및 안전성 검토를 위한 간이법의 개발)

  • 김문기;손정익;남상운
    • Journal of Bio-Environment Control
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    • v.1 no.2
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    • pp.148-153
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    • 1992
  • 본 연구는 생물생산시설의 구조설계 과정에서 초기단계의 고정하중을 합리적으로 추정하기 위한 식을 유도하여 구조설계 기준 설정에 기초자료를 제공하고, 생물생산분야 종사자가 간편하게 구조적 안전성을 진단할 수 있는 방법을 개발할 목적으로 수행하였으며 연구 결과를 요약하면 다음과 같다. 1. 국내의 온실설계자료를 수집하여 실제 하중을 산출, 분석해 본 결과 기존의 일본 시설원예기준 적용치와는 차이가 있었으며, 잠정적으로 국내 시설에의 적용을 위한 추정식을 유도하였다. 2. 지역별 설계하중을 적용하여 구조해석을 실시하고, 발생되는 응력의 크기에 따라서 풍하중 및 설하중 지배지역으로 안전설계 지역구분을 실시하였다.

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