• Tuberculosis and Respiratory Diseases
• /
• v.54 no.4
• /
• pp.429-438
• /
• 2003

Background : The mortality from acute respiratory distress syndrome(ARDS) is >40-50%. Although some prospective trials have failed to demonstrate a survival benefit of steroids in the early stages of ARDS, there are some reports showing some success with steroids in the later stages. This study observed the changes in the physiologic parameters with time in late ARDS patients who were treated with steroids. Methods : The medical charts of 28 intensive care unit patients(male:female=24:4; mean age 64 years), who had been diagnosed with refractory late ARDS ($PaO_2/FIO_2$ <200) and were treated with corticosteroids from December 1999 to July 2002, were retrospectively reviewed. The patients were divided into two groups: the weaned group(n=14), which included the patients who had been successfully weaned from a ventilator after corticosteroid therapy, and the failed group(n=14), which included the patients who had failed weaning. The physiologic parameters included the $PaO_2/FIO_2$ ratio, the positive end-expiratory pressure(PEEP) level, the $PaCO_2$, compliance, the sequential organ failure assessment(SOFA) score, the acute physiologic and the chronic health evaluation(APACHE) II score, and the Murray Lung Injury Score(LIS) in the two groups were compared from the day of mechanical ventilation(Dmv) to 7 days after the corticosteroid therapy. Results : There was no significant difference in the clinical characteristics and the physiologic parameters between the two groups prior to the corticosteroid therapy except for the SOFA score at Dmv(weaned group : $6.6{\pm}2.5$ vs failed group : $8.8{\pm}2.9$, p=0.047). However, within 7 days after corticosteroid therapy, there was significant improvement in the $PaO_2/FIO_2$ ratio, the PEEP level, the $PaCO_2$, the SOFA score, the APACHE II score, and the LIS of the weaned group compared to the failed group. Conclusions : During corticosteroid therapy in late ARDS, the continuation of corticosteroid therapy should be determined carefully in patients who do not show improvement in their physiologic parameters by day 7.

• Science of Emotion and Sensibility
• /
• v.15 no.3
• /
• pp.345-354
• /
• 2012

The purpose of this study is finding alternative parameters of the HRV so as to minimize the subjective errors by STAI and BDI, could be have two types of significant correlation levels depending on normalized method. Particularly, the LF/HF presented as the quantitative physiological parameter that can reflect both state-anxiety and trait-anxiety.

• Therapeutic Science for Rehabilitation
• /
• v.1 no.1
• /
• pp.5-16
• /
• 2012

Sensory integration started as a theory to provide a occupational therapist with a useful frame for explaining and intervening the problems which children have. Most researches on sensory processing disorder (SPD) have been found empirical evidence to support the sensory integration theory by measuring behavioral manifestations of SPD. Recently, researchers who are interested in the diagnosis of SPD have begun to use neurophysiological methods to establish objective evidence for sensory integration. These studies reported the neurophysiological indexes reflecting the maladaptive behaviors as well as the difference between children with SPD and typically developing children in using electrodermal activity, vagal tone, EEG. Future neurophysiological studies on SPD will be expected to prove the efficacy of sensory integration intervention.

• Korean Journal of Adult Nursing
• /
• v.27 no.2
• /
• pp.170-179
• /
• 2015

Purpose: To examine the relationships between self-care, social support, and biological markers in liver transplant recipients. Methods: The participants included 118 liver transplant recipients who visited outpatient clinic at Y University Hospital in Seoul from April to May, 2013. Questionnaires consisted of self-care and social support scales. The biological markers were collected by reviewing electronic medical records. Data were analyzed with descriptive statistics, t-test, ANOVA with Scheff$\acute{e}$ post-hoc test, and Pearson's correlation. Results: The self-care score was significantly higher in a patient group within 6 months post-transplant when compared to a patient group post-transplant 3 to 5 years (F=3.10, p=.018). The self-care showed positive correlation with social support with statistical significance (r=.36, p<.001). Conclusion: As the self-care in liver transplant recipients had a positive correlation with social support from family and healthcare providers, the development of comprehensive long-term nursing intervention systems including counseling, education, and support in consideration of progress of time period after transplantation is necessary to enhance self-care behaviors among this population.

• Environmental Analysis Health and Toxicology
• /
• v.20 no.1
• /
• pp.1-11
• /
• 2005

환경오염의 조기 경보 시스템으로 생체지표를 이용한 생태독성 모니터링이 최근 널리 연구되고 있다. 환경내의 생물종에서 측정한 생체지표를 이용한 환경 모니터링은 생태계 수준의 영향에 대한 예측 정보를 제공해 줄 수도 있다. 이를 위해서는 생체지표와 개체군 수준에서의 반응과의 인과관계가 밝혀져야 한다. 오염물질에 대한 생체의 반응은 분자, 세포, 생화학, 생리적, 개체, 개체군, 군집 수준에서 나타나게 되며, 이러한 각 단계별 반응은 반응 시간의 규모와 독성학적, 생태적 관련성에 따라 구분 지어 볼 수 있다. 각 개별 수준에서의 반응을 종합하면 오염물질에 노출된 생체의 전제적인 영향을 이해할 수 있으며, 이러한 이해를 바탕으로 개체군에서 나타나는 영향에 대한 인과관계를 추론할 수 있다. 생체지표와 개체군 수준의 반응과의 인과관계 정립은 효율적인 환경오염 예방기능 수행에 필수적인 과정이며, 다단계 생체 지표는 각 단계별 반응의 인과관계를 밝히기 위해 가장 적절한 접근 방법이다. 수서 무척추 생물인 Chironomus의 유충은 이러한 다단계 바이오마커 연구에 매우 적절한 생물학적 모델이다. 이 논문의 첫 번째 부분은 생체지표를 이용한 환경 모니터링을, 두 번째 부분은 Chironomus의 유충에서 생체지표의 적용에 대해서 다룬다.

• Journal of Digital Convergence
• /
• v.19 no.12
• /
• pp.649-660
• /
• 2021

The purposes of this study were to examine the effects of carebidet robot during defecation on incontinence associated dermatitis, pressure ulcer risk and biological markers in critical care patients. Data were analyzed using t-test, Chi-square test, Fisher's exact test, Mann-Whitney U-test and Repeated measures ANOVA. There was a significant difference in incontinence associated dermatitis, pressure ulcer risk, and improving biological markers between the two groups, and there were significant changes over time and the group by time interactions. The findings of the study demonstrated that carebidet robot during defecation was more effective than the current usual care in reducing incontinence associated dermatitis, pressure ulcer risk, and improving biological markers in critical care patients.

• Science of Emotion and Sensibility
• /
• v.25 no.2
• /
• pp.45-54
• /
• 2022

This study aimed to investigate the effect of subjective factors (figure recognition and stress) and objective factors (blood biochemical parameters) on body mass index by gender difference in Korean adults. This study analyzed 3,343 subjects older than 20 years according to gender using the Sixth Korean National Health and Nutrition Examination Survey database. Specifically, male subjects had higher body mass index than female subjects (p < .001) and were more frequent in the obese group. Female subjects had higher stress and platelet score than male subjects (p < .001). Male subjects had significantly higher white blood cell counts (p < .001). The factors affecting the occurrence of obesity by gender difference was highly associated with subjective figure recognition (95% CI = 0.026~0.045, p < .001), stress (95% CI = 0.487~0.925, p = .015) and white blood count (95% CI = 1.232~1.392, p < .001) in females. These findings demonstrate a gender-specific difference in recognizing subjective factors and especially the objective factors of white blood cells and platelets affecting obesity. These results can be used for obesity education or fundamental data for establishing a nursing arrangement program for Korean adults.

• The Journal of the Korea Contents Association
• /
• v.10 no.10
• /
• pp.237-245
• /
• 2010

Nerve conduction studies (NCS) are the most objective measure of nerve function and essential for the diagnosis of sub-clinical neuropathy in diabetes mellitus and diabetic polyneuropathy (DPN). This study evaluates the characteristic of electrophysiological abnormalities in DPN. Electrodiagnostic data from 120 patients with diabetic polyneuropathies and 77 control subjects were reviewed. Motor nerve conduction velocities (MNCV), distal motor latencies (DML), compound muscle action potential (CMAP) amplitudes, No potential frequency and conduction block were analyzed. Data were normalized based on normative reference values, and the proportion of nerves with abnormal values in the lower and upper limbs were evaluated. DPN was systemic demyelinating peripheral polyneuropathy and more severe abnormal nerve conduction was found in lower limbs than in upper limbs. The abnormal degree was more severe in peroneal nerve. It was no statistically significant difference of conduction block in control and DPN group. Our findings suggest that DPN had more common and severe peroneal nerve involvement in the motor nerve conduction studies (MNCS). These findings have important implications for the electrophysiological evaluation of DPN.

• Korean Journal of Microbiology
• /
• v.25 no.4
• /
• pp.318-327
• /
• 1987

Taxonomic composition and diversity were wxamined by statistical analysis for bacterial communities in surface waters of the Sudong Stream, a tributary of North Han River. For total 282 isolates, Flavobacterium, Aeromonas and Enterobacteriaceae was identified by the deterministic schemes as a major group above 50% of total isolates in all sampling sites. Morphological, biochemical and physiological characteristics were numerically analyzed for bacterial isolates from each site and clustered into 15-28 groups. Not all statistically clustered groups were identical to the groups derived from deterministic identification. Especially, consistent relationship was not found in dendrograms for the groups with each a single strain which gas peculiar sugar-degrading activity. At a level of 80% similarity, bacterial diversity (H) was ranged as 2.37-3.14, and it was suggested that the research area was oligotrophic-mesotrophic status. Regional distribution of bacterial community was most heterogeneous at the site where large input of allochthonous materials or bacteria were occurred. And that was the significant factor for the compositions of bacterial communities in the Sudong stream.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2003.10a
• /
• pp.78-79
• /
• 2003