• Proceedings of the Korea Information Processing Society Conference
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• 2007.11a
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• pp.86-89
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• 2007

현대 사회의 건강관리 분야에서 기존의 서양의학이 아닌 한의학을 이용하는 것에 관심이 증대되고 있는 실정이다. 이에 한의학의 진단 이론인 사진법 중 가장 뛰어난 망진을 활용한 진단기기의 개발이 의료비 절감 및 국민건강 증진에 기여할 것으로 사료된다. 본 논문에서는 망진 중 찰색을 위한 진단기술 개발을 위한 연구를 진행 하였으며 실험을 위해 일정한 환경을 설정하고 이와 같은 환경에서 임상자료를 수집하여 색상 분석을 실행하고 디지털 색 체계 분석을 위한 연구를 진행하였다. 특히 실험을 통해 찰색에 필요한 오색(흰색, 검정색, 빨간색, 파란색, 노란색)의 추출에 적합한 디지털 색 체계로서 LAB 색체계의 효율성을 밝히고 이를 통한 실제 피부색 비교 및 분석을 진행하였다. 최종적으로 실험의 의한 피부색 분석으로 찰색에 유용한 기준 설정을 행하고자 한다.

• Clinical and Experimental Pediatrics
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• v.45 no.2
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• pp.232-239
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• 2002

Purpose : Renal cystic diseases comprise a mixed group of heritable, developmental and acquired disorders. Recently the use of imaging modalities such as ultrasonography and radionuclide scanning has increased the detection rate of renal cystic diseases. We studied to review the clinical features and treatment of renal cystic diseases in children. Methods : This study was performed in 95 children with renal cystic diseases in the Department of Pediatrics, Asan Medical Center from October 1989 to June 2001. Results : In 95 patients, there were 55 cases(58.0%) with multicystic dysplastic kidney(MCDK), 19 cases(20.0%) with simple renal cysts, 13 cases(13.7%) with hereditary polycystic kidney diseases( 7 with autosomal recessive type, 5 with autosomal dominant type, 1 with undetermined), 6 cases(6.3%) with renal cysts in tuberous sclerosis and 1 case(1.0%) with medullary cystic disease. All MCDK patients had no renal dysfunction and hypertension during the follow-up period. Three out of 13 with polycystic kidney diseases had progressed to end-stage renal disease during the follow-up period. One case with a simple cyst underwent laparoscopic malsupialization for decompression. Conclusion : Renal cystic diseases have diverse clinicopathologic features and variable prognosis. We emphasize that routine follow-up should be performed to prevent and to detect early treatable complication in renal cystic diseases. Therefore, their natural history and treatment need further investigation and long term follow-up is required.

• Clinical and Experimental Pediatrics
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• v.45 no.3
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• pp.311-319
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• 2002

Purpose : We have performed this study to obtain reference data for the distribution of chromosomal aberrations in Korea. Methods : We analyzed 1,180 chromosomal study cases from Kwang ju Christian Hospital during the past 25 years. 756 cases suspected of characteristic chromosomal aberration syndromes and 424 cases with hermaphroditism, mild sexual abnormalities, multiple anomalies, or mental & growth retardation were included. Results : The male to female ratio of autosomal aberration syndromes was 1.2 : 1. 78.6% of autosomal aberrations were diagnosed under 1 year of age, whereas 89.8% of sex chromosomal aberrations were diagnosed over 12 years of age. Among 1,180 cases, 612 ones had chromosomal aberrations(51.9%) : 590 of 756 cases suspected of chromosomal aberration syndromes had aberrations( 78.0%), whereas 22 of 424 showing the above other features had aberrations(5.2%). Autosomal aberrations appeared in 514 cases(83.8%) and sex chromosomal aberrations appeared in 98 cases(16.2%). The most frequently observed abberation in autosomal aberrations was Down syndrome, followed by E, D, B, A and C group aberrations. The most common abberation in sex chromosomal aberrations was Turner syndrome, followed by Klinefelter syndrome and Fragile X syndrome. Conclusion : It is of vital importance that patients suspected of chromosomal aberrations undergo chromosomal analysis. Further advanced chromosomal staining and molecular genetic methods will raise the detection rate of chromosomal aberrations.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.10 no.2
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• pp.163-170
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• 2016

The purpose of this study was to verify the emotional response of user to LED light colors in healing bed system in cypress tree. Eight colors of LED light were provided including red, orange, yellow, green, blue, indigo, violet and white. And three illumination color temperature were provided including 3,000K, 5,000K, 8,000K. Seven subjects in their twenties were involved without the medical history of eyes and heart disorders. The subjects were exposed to LED lighting during 5 minutes and their emotional response was evaluated through the following: first, at the physiological effect heart rate variability(HRV) was measured during the stimulation; second, at the emotion level the subjects were asked about lighting color and color temperature through a survey. Results, lower color temperature of 3,000K and green color shows high value on HRV. We have found that there is a difference of physiological and emotion level effect depending on color stimulus. This study could be applied to reference data to analysis of a decrease in fatique and charges of brain waves for color stimulus.

• The KIPS Transactions:PartB
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• v.15B no.5
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• pp.397-406
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• 2008

Despite the effectiveness of oriental medical practice in the diagnosis of symptoms and providing cure to it, the preferences in western medicinal values is socially prevalent. The diagnosis of a disease using western medicinal practices provides us with an objective diagnostic result, however, decisions by oriental doctors are based on their heuristic intuitions developed by practice and experience. Objective solutions for the cure of symptoms using oriental medical therapy can have a high impact on the world market. Therefore, development of diagnostic machines based on oriental therapy can enhance the Ocular Inspection which is evaluated as one of the best diagnostic treatment among Oriental Medical Science, is not researched much compared to other diagnoses. Because there is no color diagnosis rules for digital machines to analyze the actual color, looking at the person's face color is one of the most important components to diagnose the disease or illness. The thesis proposes the implementation of absolute observing a person's face color standards of the color settings for objective diagnosis. As a results, comparative digital color analysis for observing a person's face color can be the most effective rule based Color scheme system to diagnose disease. A standard solution for the researching conditions is suggested to reduce the variable which may occur depending on the differences between the researching conditions.

• The Korean Journal of Zoology
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• v.12 no.1
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• pp.22-28
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• 1969

In order to see if any suppressor system for the SD action was involved in natural populations of D. melanogaster samples from the populations of nine localities in Korea, Choonchun, Yusoo, Namhai, Shinchon(Seoul), Kwangjoo(Kyunggi), Koonsan, Kwangjoo(Chunnam), Jejoo and Pusan were analyzed by using the mating scheme for locating the suppressor on chromosome pairs. And also two kinds of recombinant SD lines R-1, the American line and $R(SD^NH -1)-1$, the Japanese one were used in order to see any difference of the response of the suppressor for differently originated SD. The results of the experiment are given below. (1) The suppressor system was involved in all lines of natural populations from nine localities of Korea. (2) Most of the suppressors were found to be located on the X chromosome and only a few lines from three populations showed to carry the suppressors on the second chromosome and on the third or fourth chromosoem. (3) The response of the suppressor for differently originated SD lines showed no significant difference.

• Journal of Life Science
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• v.22 no.11
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• pp.1444-1450
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• 2012

The purpose of the present research is to investigate the effects of acute soccer game on serum levels of neurotrophins and neurocognitive function. The subjects of the research were 15 healthy male adolescents. The subjects underwent two experiments: one experiment in the soccer game treatment (SOC) condition, and the other in the self-study treatment (CON) condition. Blood samples were collected at three times: before treatment (Pre), after treatment (Post), and 2 hours post treatment (Post-2 h) for the analyses of serum brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and insulin-like growth factor-1 (IGF-1). For the measurements of neurocognitive functions, the Stroop Color-Word test was performed at blood collecting times. The results of the research showed that the serum levels of BDNF, NGF, and IGF-1 were significantly increased after the soccer game (p<0.05), and significantly higher in SOC than CON at Post (p<0.05). In the Stroop Color-Word test, significantly increased scores were observed in SOC at Post (p<0.05), and significantly higher in SOC than in CON at Post and Post-2 h (p<0.05). These results suggest that acute soccer game has positive effects on neurocognitive functions by increasing the neurotrophins.

• The Korean Journal of Zoology
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• v.13 no.1
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• pp.15-20
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• 1970

The present study was undertaken in an attempt to see if the segregation frequency of a third chromosome was changed by changing the sex chromosome which were free of SD in the second chromosome. The eight genotype males having different sex chromosome constitution each were constructed by appropriate matings and the two standard laboratory stocks of Drosophila melanogaster, e and se were used as the third chromosome recessive markers for the present experiment. The results of the present investigation are given below: 1. The k values which are the proportion of the se third chromosomes recovered among progeny flies from the mating of se/e males to e females were highly signiicantly different among the four genotypes and between the two sexes,and the interaction of genotype and sex was significantly different. Thus the setregation frequency of the se third chromosome in the male, when made heterozygous with the e third chromosome, was dependent upon the sex chromosome constitution. 2. Both of the k(Woman) and the k(man) remains roughly constant among genotypes. 3. The sex ratio o the se progeny class was highly significantly heterogeneous among the four genotypes but it was homogeneous for the e progeny class. 4. The values of the k(man) and the sex ratio of the se progeny class, on the average, were higher than that of the k(Woman) and of the e progeny class, respectively. 5. Those phenomena suggest that some sort of prezygotic selection could be operating such that the combination of the e third chromosome and the Y chromosome tends to be eliminated before fertilization. This tendency argues for a re-examination of the viability estimations of Drosophila melanogaster.

• Journal of Life Science
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• v.17 no.6 s.86
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• pp.741-747
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• 2007

In the azoospermic patients, there are many of undiagnosed factors related to genetic bases. Among them, Klinefelter's syndrome (47,XXY; KS) and Y-chromosomal microdeletion with normal karyotype(46,XY; YMNK) are the most frequent causes of male infertility. This research focused on the comparative analysis of YMNK (n = 66) and K5 (n = 30) patients suffered from male infertility in Korean population. We used the polymerase chain reaction (PCR) approach including 19 pairs of sequence-tagged site (STS) primers for detecting the Y-chromosomal microdeletion on AZFa, b, c regions, indicating that Y chromosomal microdeletions were almost evenly occurred in AZF all regions in Korean population. Comparative analysis indicated that 34.9% YMNK and 73.4% KS patients harbored the microdeleted Y-chromosome. It seems to be high instability of Y-chromosome in KS patients than that of YMNK infertility patients. Taken together, genome instability containing microdeletion could bring male infertility with the disturbance of normal spermatogenesis.

• Korean Journal of Poultry Science
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• v.20 no.4
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• pp.177-188
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• 1993

This study was performed to find out the reasonable sexing methods In the chicken, obtain the basic information for the mechanisms related to chicken sexual differentiation and identify the genes which known to involved in chicken sex differentiation. The chromosome analysis of chicken embryonic fibroblast was a simple method to determine sex of chicken by means of Z and W chromosome identification. The bands of female chicken genomic DNA digested with Xho Ⅰ and Eco RI restriction endonuclease showed to be useful in direct sex determination and these repetitive sequences of Xho Ⅰ and Eco RI families were proposed to be very homologous in their sequences by colony hybridization analysis. Seven of 150 random primers were selected to amplify the W chromosome-specific band by using arbitrary primed PCR and three of them were useful to identify the sex of chicken. To identify the sex differentiation genes in the chicken, PCR for the amplification of ZFY and SRY sequences was performed. ZFY and SRY sequences were amplified successfully in the chicken genome, implying that chicken genome might have the sex-related conserved sequences similar to mammalian ones. The PCR products of ZFY amplification were the same in both sexes, suggesting that these sequences may be located on autosome or Z chromosome. The profile of PCR amplification for SRY sequences showed variation between sexes, but this result was not enough to specify whether the SRY gene in chicken is on the autosome or sex chromosome.