• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.8
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• pp.5336-5342
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• 2015

Although demand for scar treatment has been rising as our quality of life is improved, most scar treatment products rely on importation. Enkephalin is one of the neuropeptides secreted from neuronal ends. As both skin and neuron are derived from the exoderm during the development process, skin cells express opioid receptors as neuronal cells do. Opioid receptors are categorized into three types, mu(m)-, delta(d)-, and kappa(k)- opioid receptors, all of which are directly involved in the wound healing process. In this study, enkephalin derivatives are synthesized by Alanin Scan and their efficacy was evaluated and compared. In vitro wound healing effects, stimulatory effects of collagen synthesis, and skin hydration effects were also evaluated and confirmed. Among Enkephalin derivatives, AS13 showed highest wound healing effect.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.06a
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• pp.257-260
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• 2022

국제표준 3차원 포인트 클라우드 압축 기술인 MPEG(Moving Picture Experts Group)-I(Immersive) V-PCC(Video-based Point Cloud Compression)에는 점유 맵(Occupancy Map) 손실/무손실 압축 기술이 포함되어 있다. V-PCC는 기존에 보급되어 있는 2차원 비디오 코덱(H.264/AVC, HEVC, AV1 등)을 그대로 활용할 수 있는 장점이 있는데, 대부분의 소비자 영상 기기에 포함되어 있는 2차원 비디오 복호화기 HW는 무손실을 지원하지 않는다. 따라서 V-PCC 복호화기의 폭넓은 상용화를 위해서는 부호화기에서 점유 맵의 손실 압축이 필수적이다. 본 논문은 V-PCC 부호화기의 점유 맵을 최소한의 압축 효율 저하로 손실 압축하기 위해 다양한 파라미터 실험을 통한 최적의 파라미터 값을 제시한다.

• Journal of Aquaculture
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• v.11 no.2
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• pp.167-172
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• 1998

Rhynchocypris oxycephalus was incised through the midlateral line between the dorsal and pectoral fins and the wounds were closed with absorbable synthetic suture, and here we describe histological details on the nature of second-intention wound healing, rate of healing, and the nature of granulation tissue contraction. Postoperative survivals were 95% and 99%, compared to 100% for counterpart control fish, among fish at just and 7 days after surgery, respectively. By 14~42 days after surgery, fish had no mortality. The granulation tissue was epithelialized from day 7 through day 22 postsurgery. By 28 days postsurgery, the granulation tissue had contracted the wound margins into apposition. By 35~42 days postsurgery, the granulatin tissue contained collagen fiber and the epidermis contained well-differentiated alarm substance cells ; thus, the epidermis over the wound site was histologically normal in most fish, showed that wound healing was essentially complete within 35 days of surgery.

• Journal of Digital Convergence
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• v.12 no.5
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• pp.467-477
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• 2014

The goal of this study is to explore 'color meditation programs' for wounded heart healing of University students. Color meditation was found to alleviate negative psychological symptoms of young people and to raise their quality of life. Furthermore this survey was investigated in a way that participants who are not familiar with meditation activities could access this program without resistance. Also the characteristic points of this program are to be properly reconstructed and supplemented so that it can be applied without any limitations in schools. The satisfaction with color meditation program rather than the motivation of participation in it was determined to affect mental health. These results suggest that simply participating in color meditation program does not mean influencing mental health. Understanding and being satisfied with color meditation was found to be the key to mental health.

• Korean Journal of Optics and Photonics
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• v.34 no.2
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• pp.45-52
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• 2023

In this study, we have investigated the effect of photobiomodulation (PBM) on corneal wound healing, using a low-power light-emitting diode (LED) at different wavelengths. We found that LEDs with wavelengths ranging from 623 to 940 nm had no significant cytotoxic effects on corneal epithelial cells. The effect of PBM on promoting cell migration was analyzed by scratch assay, and it was found that PBM at 623 nm significantly increased cell migration and promoted wound healing. Furthermore, the expression of genes related to cell migration and wound healing was analyzed, and it was found that PBM at 623 nm upregulated the expression of the genes FGF-1 and MMP2, which are known to promote cell proliferation and extracellular matrix degradation. These findings suggest that PBM with low-powered light at specific wavelengths, particularly 623 nm, could be utilized to treat corneal injury.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.17 no.1
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• pp.201-221
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• 2006

This paper attempts to highlight such issues as the personal psychological problems due to the aging, and tries to investigate the effectiveness and the potentials of bibliotherapy to heal the wounded hearts of people who suffer from aging. Portrayed through a qualitative surveys and interviews with five subjects selected by the researchers, discussions were elaborated around three factors such as physical, cognitive. and social factors. The participants. throughout the study, came to understand and to narrate their own problems objectively and to discern their wounds. It was also observed that they felt relieved and stable after reading the books presented by the researchers. As a result, physical decline. isolation from family members, solitude in society and decline of self-esteem they have experienced since their mid-40s were recognized as natural changes from aging which were to overcome.

• Childhood Kidney Diseases
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• v.16 no.2
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• pp.115-120
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• 2012

Purpose: We aimed to evaluate the efficacy of Octyl-2-cyanoacrylate (Dermabond$^{TM}$) as a topical skin adhesive for pediatric urologic open surgery. Methods: From August 2010 to August 2011, we retrospectively evaluated pediatric patients who underwent urologic open surgery at our institution. A total of 128 pediatric patients with 210 incisions used Dermabond$^{TM}$ for skin closure. Results: We divided the 128 patients into 3 groups according to type of surgery. Group 1 underwent hydrocelectomy (55 cases, 41.3%), Group 2 underwent orchiopexy (43 cases, 32.3%), Group 3 underwent penoplasty (35 cases, 26.4%). One hundred and twenty eight patients who underwent 133 surgeries in total, with a total of 210 incisions visited our outpatient department postoperatively, and a total of 5 wound complications (2.3%) occurred, but were simple inflammations and no dehiscence was observed. When analyzed according to groups, no wound problems occurred in Group 1 (0/55, 0%), one occurred in Group 2 (1/43, 2.3%) and four cases occurred in Group 3 (4/35, 11.4%) respectively. When re-analyzed according to wound locations, one occurred in an inguinal wound (1/120, 0.83%), none occurred in scrotal wounds (0/55, 0%), and four occurred in penile wounds (4/35, 11.4%). In Group 3, the incidence of penile wounds was significantly increased compared to other groups (P=0.008). All 5 wound problems were inflammatory and healed at an average of 13.8 days (13-15 days) with antibiotic ointment application only. Conclusion: Dermabond$^{TM}$ is feasible and safe topical skin adhesive alternative to standard skin suture in pediatric urologic surgery. However, further research about its efficacy and safety could be valuable in the future.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.20 no.1
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• pp.14-24
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• 1994

Mma-5 and Malva are extracts from a defined seaweed of the Rhodophyceae family and an annual or perenial plant, respectively. They have traditionally a significant stimulating properties such as protein synthesis, astringent, emollient, and et al.. In order to investigate the effect on wound healing, we studied for cell migration, cell attachment, and cell proliferation in vitro. The results of present study demonstrated that MMA-5 and Malva extract had the effect on wound healing, therefore we suggested that they could be effective materials to be applied to Cosmetic products.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.14 no.2
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• pp.41-57
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• 2003

The purpose of this study is to present method on activation of bibliotherapy for children and young people in school library. So the first part of paper is to understand mental state of children and youth. Then second part is to develop library collection for bibliotherapy in school library. The last Part is to develop bibliotherapy Program for children and youth by school librarian.

• Applied Biological Chemistry
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• v.39 no.2
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• pp.104-111
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• 1996

We have isolated several proteinase inhibitor II genes pin2 from a Russet Burbank potato DNA library. One of these, pin2T was subcloned and a 1.8 kb Xbal/Nsil insert was sequenced. This fragment contained the complete Inhibitor II gene including 965 Up of flanking DNA upstream from the gene and 200 bp of flanking DNA downstream from the gene. The open reading frame encodes a protein that is similar to other reported proteinase Inhibitor II proteins. The DNA sequence of the 5' flanking region of pin2T from -714 to +1 is highly homologous (91% identity) with that of the previously isolated wound-inducible pin2K. There are, however, four small deletions in the pin2T promoter which are located at -221 to -200, -263 to -254, -523 to -426 and -759 to -708 relative to the transcription start site of the wound-inducible pin2K. Three of these deletions map to a portion of the promoter that controls the wound-inducibility of the proteinase inhibitor genes. Chimeric genes containing the promoter of the pin2T gene linked with the both CAT and GUS were constructed and transfered into tobacco plants. Analysis of these plants indicated that pin2T is not a wound-inducible gene but is expressed at low levels. Thus, wound-inducibility is lost with the concomitant natural deletion of three small regions of the promoter. Comparision of the sequences deleted in pin2T relative to the pin2K with Genebank sequences indicates that the deleted sequences contain a motif (consensus 5'-AGTAAA-3') that is found in many other wound-inducible genes but not easily found in the published promoter sequences of other plant genes. Nuclear proteins from unwounded and wounded potato leaves were bound to the proximal promoter region, downstream of the 5'-AGTAAA-3', of pin2T. The comparison of the pin2T gone with the pin2K gene indicates that the natural internal promoter deletions are likely responsible for loss of the wound-inducible phenotype in the pin2T gene.