• Title/Summary/Keyword: 상세완화

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Anti-inflammatory and Anti-allergic Effects of Herbal Extracts on Atopic Dermatitis ( Part II ) (약용식물 추출물의 아토피성 피부염에 대한 항염증 및 항알레르기 효과 (제 2 보))

  • Rang, Moon-Jeong
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.1
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    • pp.173-182
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    • 2013
  • Atopic dermatitis is a chronic, relapsing inflammatory skin disease associated with dysfunction of skin barrier and cutaneous hyper-reactivity to environmental triggers. In the previous study, cytotoxicity, antioxidant, anti-inflammatory and anti-allergic activities were investigated for various herbal extracts such as Aloe vera L. (AV), Viola mandshurica W. Becker (VM), Punica granatum L. (PG), and Dendrobium nobile L. (DN) in order to develop effective therapeutic herbal extracts for atopic dermatitis, In this study, anti-inflammatory activities of these herb extracts in lipopolysaccharide (LPS)-induced macrophage RAW264.7 cells were further examined to find the underlying molecular mechanisms. The RT-PCR (reverse transcription polymerase chain reaction) analysis showed that PG, DN and AV inhibited effectively the gene expression of pro-inflammatory cytokines IL-6 and IL-$1{\beta}$ in LPS-stimulated macrophages, while VM did not. The transfection and luciferase analysis exhibited that all herbal extracts hindered the activation of transcription nuclear factor kappa B (NF-${\kappa}B$). The western blot analysis indicated that AV blocked the activation of only JNK MAP (c-Jun N-terminal kinase mitogen-activated protein) kinase not p38 MAP kinase, while VM, PG and DN did not show the activation of both JNK and p38 MAP kinases. These results suggest that AV, VM, PG, and DN have anti-inflammatory activities and thus have the potential to reduce and alleviate the symptoms of atopic dermatitis.

An Analysis on the Anti-poverty Effectiveness of Public and Private Income Transfers; After the Enactment of National Basic Livelihood Security Act (공적 이전과 사적 이전의 빈곤 감소 효과 분석 : 기초생활보장제도 도입 이후를 중심으로)

  • Hong, Kyung-Zoon
    • Korean Journal of Social Welfare
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    • v.50
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    • pp.61-85
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    • 2002
  • Using the 2001 Family Income and Expenditure Survey micro-data, this study analyses the anti-poverty effectiveness of public and private income transfers. In this study, the anti-poverty effectiveness of income transfers is summarized in two ways; 1) the poverty reduction effect of the income transfers, and 2) the poverty reduction efficiency of the income transfers. The poverty reduction effects are measured with several poverty indices including the head-count ratio, poverty gap, and Sen index. Using Beckerman's model, this study also analyses the poverty reduction efficiency of income transfers. This analysis documents substantial differences in the anti-poverty effectiveness of public and private income transfers. Although the private income transfers contribute more to reduce the head-count poverty ratio and Sen index than public income transfers, their differences are significantly reduced after the enactment of National Basic Livelihood Security Act. The results also reveal that the anti-poverty effectiveness of public and private income transfers vary by the types of families. In families headed by elderly and working aged, private income transfers have more anti-poverty effectiveness. But, public income transfers contribute more to reduce poverty than private income transfers among families headed by single adults with children. The results of this study suggest that recent changes in anti-poverty policies in Korea have been strengthened the Government's responsibility. And more importantly, to effectively reduce poverty among the poor families, anti-poverty polices must be designed to consider different family types.

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A Study on the Relationship between Land Cover Type and Urban Temperature - focused on Gimhae city - (토지피복유형 특성과 도시 온도의 관계 분석 - 김해시를 대상으로 -)

  • SONG, Bong-Geun;PARK, Kyung-Hun
    • Journal of the Korean Association of Geographic Information Studies
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    • v.22 no.2
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    • pp.65-81
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    • 2019
  • This study analyzed the relationship of land cover type, urban temperature in Gimhae city, Gyeongsangnam-do, South Korea. Date were used for land cover map, MODIS LST, and detailed temperature data on the Korean Peninsula based on RCP between 2000 and 2010. The correlation between urban area and surface temperature was 0.417, 0.512 for agricultural area and -0.607 for forest area. The correlation between surface temperature and air temperature was 0.301. The relationship with air temperature was analyzed as 0.275 for urban area, agriculture area 0.226, forest area 0.350. Urban and agricultural areas showed increased surface and air temperature as the area increased, while forest areas showed opposite improvements. In structural equation models, urban and agricultural areas had direct effects on the rise of surface temperature, whle forest areas had direct effects on the reduction of air temperature. In the future, it is necessary to use measured temperature data near the surface to understand the relationship between surface temperature and temperature according to the changes in spatial characteristics, which will prepare measures for urban heat island mitigation at the level of urban and environmental planning.

Management Strategies of Local Cold Air in Jeongmaek for utilizing urban Ventilation Corridor - A Case Study of the Nak-nam Jeongmaek - (바람길 활용을 위한 정맥의 찬공기 관리 방안 - 낙남정맥을 사례로 -)

  • EUM, Jeong-Hee
    • Journal of the Korean Association of Geographic Information Studies
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    • v.22 no.1
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    • pp.154-167
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    • 2019
  • As urban heat environment problems occur due to climate change, urban thermal environmental problems such as heat waves and tropical nights are becoming more serious in cities. In South Korea, forest areas favorable for generating cold air account for about 63 percent of the land area. Furthermore, the Jeongmaek, the axis of the main mountain ranges of Korea, is located close to the cities. Hence, the management of cold air is an effective way to improve the thermal environment of Korean cities. We selected the Nak-nam Jeongmaek located in the southern part of Korean Peninsular as well as two cities (Jinju-si and Sancheong-gun) located at the Jeongmaek to analyze its cold air characteristics and suggest management strategies of cold air. We used KALM (Kaltluftabflussmodell), a cold air simulation model developed in Germany and identified both the cold air flow and the height of cold air layer generated during 6 hours at night. As a result, the cold air flow generated in the Jeongmaek became clear and the height of cold air layer increased with time. Based on the results, we proposed management plans to maintain and expand the cold air flow. For example, forest areas with active cold air generation were designated as 'cold air conservation areas', and areas requiring management for good cold air flow were as 'cold air management areas'. This study is expected to be useful for establishing systematic urban ventilation plan to improve thermal environment in Korea cities.

Securing Safety in Collaborative Cyber-Physical Systems Through Fault Criticality Analysis (협업 사이버물리시스템의 결함 치명도 분석을 통한 안전성 확보)

  • Hussain, Manzoor;Ali, Nazakat;Hong, Jang-Eui
    • KIPS Transactions on Software and Data Engineering
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    • v.10 no.8
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    • pp.287-300
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    • 2021
  • Collaborative Cyber-Physical Systems (CCPS) are those systems that contain tightly coupled physical and cyber components, massively interconnected subsystems, and collaborate to achieve a common goal. The safety of a single Cyber-Physical System (CPS) can be achieved by following the safety standards such as ISO 26262 and IEC 61508 or by applying hazard analysis techniques. However, due to the complex, highly interconnected, heterogeneous, and collaborative nature of CCPS, a fault in one CPS's components can trigger many other faults in other collaborating CPSs. Therefore, a safety assurance technique based on fault criticality analysis would require to ensure safety in CCPS. This paper presents a Fault Criticality Matrix (FCM) implemented in our tool called CPSTracer, which contains several data such as identified fault, fault criticality, safety guard, etc. The proposed FCM is based on composite hazard analysis and content-based relationships among the hazard analysis artifacts, and ensures that the safety guard controls the identified faults at design time; thus, we can effectively manage and control the fault at the design phase to ensure the safe development of CPSs. To justify our approach, we introduce a case study on the Platooning system (a collaborative CPS). We perform the criticality analysis of the Platooning system using FCM in our developed tool. After the detailed fault criticality analysis, we investigate the results to check the appropriateness and effectiveness with two research questions. Also, by performing simulation for the Platooning, we showed that the rate of collision of the Platooning system without using FCM was quite high as compared to the rate of collisions of the system after analyzing the fault criticality using FCM.

A Study on Proving RMF A&A in Real World for Weapon System Development (무기체계 개발을 위한 RMF A&A의 실증에 관한 연구)

  • Cho, Kwangsoo;Kim, Seungjoo
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.31 no.4
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    • pp.817-839
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    • 2021
  • To manage software safely, the military acquires and manages products in accordance with the RMF A&A. RMF A&A is standard for acquiring IT products used in the military. And it covers the requirements, acquisition through evaluation and maintenance of products. According to the RMF A&A, product development activities should reflect the risks of the military. In other words, developers have mitigated the risks through security by design and supply chain security. And they submit evidence proving that they have properly comply with RMF A&A's security requirements, and the military will evaluate the evidence to determine whether to acquire IT product. Previously, case study of RMF A&A have been already conducted. But it is difficult to apply in real-world, because it only address part of RMF A&A and detailed information is confidential. In this paper, we propose the evidence fulfilling method that can satisfy the requirements of the RMF A&A. Furthermore, we apply the proposed method to real-world drone system for verifying our method meets the RMF A&A.

Effect of Propeller Eccentric Thrust Change on Propusion Shafting System (프로펠러 편심추력변동이 축계안정성에 미치는 영향 연구)

  • Lee, Ji-woong;Lee, Jae-ung
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.7
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    • pp.1082-1087
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    • 2021
  • The propeller shaft has different pattern of behaviors at each static, dynamic, and transient condition to a ship shaft system due to the effects of propeller weight and eccentric thrust, which increases the potential risk of bearing failure by causing local load variations. To prevent this, the various research of the shafting system has been conducted with the emphasis on optimizing the relative slope and oil film retention between propeller shaft and stern tube bearing at quasi-static condition, mainly with respect to the Rules for the Classification of Steel Ships. However, to guarantee a stability of the shafting system, it is necessary to consider the dynamic condition including the transient state due to the sudden change in the stern wakefield during rudder turn. In this context, this study cross-validated the ef ect of propeller shaft behavior on the stern tube bearing during port turn operation, which is a typical transient condition, by using the strain gauge method and displacement sensor for 50,000 DWT medium class tanker. And it was confirmed that the propeller eccentric thrust change showing relief the load of the stern tube bearing.

An analysis of examination items for secondary Home Economics teaching certification - Focusing on evaluation content elements of Home Economics - (중등 "가정" 교사 임용시험 문항 분석 - 평가 영역별 평가 내용 요소를 기준으로 -)

  • Jung, Sang-Hee;Park, Mi-Jeong;Chae, Jung-Hyun
    • Journal of Korean Home Economics Education Association
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    • v.24 no.2
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    • pp.135-154
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    • 2012
  • The purpose of this study was to investigate the trends of HE exam questions through analyzing the examination items for secondary Home Economics(HE) teaching certification from 2002 to 2011. The results of the study were as follows: First, regarding the analysis on pedagogy of HE course, it accounted for 30.9% of the total questions, and recently, it increased to 35%. Regarding the ratio of questions by each evaluation element, 'practice of teaching and learning methods for HE course'(33.2%) had the highest ratio, and 'essence of the education of HE'(3.2%) had the lowest ratio. Second, regarding the analysis on eating habits, it amounted to 17.5% of the total questions, and recently reached 15%. With regard to the ratio of each evaluation element, 'cooking theory and practice'(26.1%) had the highest ratio, and 'culture of eating habits'(3.7%) had the lowest ratio. Third, regarding the analysis on clothing habits, it accounted 15% of the total questions, and recently reached 12.5%. With regard to the ratio of each evaluation element, 'clothing management'(25.1%) and 'production of clothing and living necessaries'(25.1%) had the highest ratio, and 'selection of clothing and self-expression'(3.0%) had the lowest ratio. Fourth, regarding the analysis on housing life, it accounted for 11% of the total questions, and recently reaches 12.5%. With regard to each evaluation element, 'the understanding of housing life culture'(22.5%) had the highest ratio, and 'the understanding of housing interior design'(10.7%) had the lowest ratio. Fifth, regarding the analysis on daily life as a consumer, it accounted for 12.4%, and recently reaches 12.5%. With regard to the ratio of each evaluation element 'management of domestic resources'(34%) had the highest ratio, and 'planning of entire life and domestic welfare'(0%) had the zero ratio. Sixth, regarding the analysis on family life, it accounted for 13.3% of the total questions, and recently reaches 12.5%. With regard to the ratio of each evaluation element, 'the understanding of family and the changes in family'(23.8%) had the highest ratio, and 'marriage and the development of family'(2%) had the lowest ratio.

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Analysis and Implication on the International Regulations related to Unmanned Aircraft -with emphasis on ICAO, U.S.A., Germany, Australia- (세계 무인항공기 운용 관련 규제 분석과 시사점 - ICAO, 미국, 독일, 호주를 중심으로 -)

  • Kim, Dong-Uk;Kim, Ji-Hoon;Kim, Sung-Mi;Kwon, Ky-Beom
    • The Korean Journal of Air & Space Law and Policy
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    • v.32 no.1
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    • pp.225-285
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    • 2017
  • In regard to the regulations related to the RPA(Remotely Piloted Aircraft), which is sometimes called in other countries as UA(Unmanned Aircraft), ICAO stipulates the regulations in the 'RPAS manual (2015)' in detail based on the 'Chicago Convention' in 1944, and enacts provisions for the Rules of UAS or RPAS. Other contries stipulates them such as the Federal Airline Rules (14 CFR), Public Law (112-95) in the United States, the Air Transport Act, Air Transport Order, Air Transport Authorization Order (through revision in "Regulations to operating Rules on unmanned aerial System") based on EASA Regulation (EC) No.216/2008 in the case of unmanned aircaft under 150kg in Germany, and Civil Aviation Act (CAA 1998), Civil Aviation Act 101 (CASR Part 101) in Australia. Commonly, these laws exclude the model aircraft for leisure purpose and require pilots on the ground, not onboard aricraft, capable of controlling RPA. The laws also require that all managements necessary to operate RPA and pilots safely and efficiently under the structure of the unmanned aircraft system within the scope of the regulations. Each country classifies the RPA as an aircraft less than 25kg. Australia and Germany further break down the RPA at a lower weight. ICAO stipulates all general aviation operations, including commercial operation, in accordance with Annex 6 of the Chicago Convention, and it also applies to RPAs operations. However, passenger transportation using RPAs is excluded. If the operational scope of the RPAs includes the airspace of another country, the special permission of the relevant country shall be required 7 days before the flight date with detail flight plan submitted. In accordance with Federal Aviation Regulation 107 in the United States, a small non-leisure RPA may be operated within line-of-sight of a responsible navigator or observer during the day in the speed range up to 161 km/hr (87 knots) and to the height up to 122 m (400 ft) from surface or water. RPA must yield flight path to other aircraft, and is prohibited to load dangerous materials or to operate more than two RPAs at the same time. In Germany, the regulations on UAS except for leisure and sports provide duty to avoidance of airborne collisions and other provisions related to ground safety and individual privacy. Although commercial UAS of 5 kg or less can be freely operated without approval by relaxing the existing regulatory requirements, all the UAS regardless of the weight must be operated below an altitude of 100 meters with continuous monitoring and pilot control. Australia was the first country to regulate unmanned aircraft in 2001, and its regulations have impacts on the unmanned aircraft laws of ICAO, FAA, and EASA. In order to improve the utiliity of unmanned aircraft which is considered to be low risk, the regulation conditions were relaxed through the revision in 2016 by adding the concept "Excluded RPA". In the case of excluded RPA, it can be operated without special permission even for commercial purpose. Furthermore, disscussions on a new standard manual is being conducted for further flexibility of the current regulations.

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A Study on Practices and Improvement Factors of Financial Disclosures in early stages of IFRS Adoption - An Integrative Approach of Korean Cases: Embracing Views of Reporting Entities and Users of Financial Statements (IFRS 공시 실태 개선방안에 대한 소고 - 보고기업, 정보이용자 요인을 고려한 통합적 접근 -)

  • Kim, Hee-Suk
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.7 no.2
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    • pp.113-127
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    • 2012
  • From the end of 1st quarter of 2012, Korean mandatory firms had started releasing financial reports conforming to the K-IFRS(Korean adopted International Financial Reporting Standards). Major characteristics of IFRS, such as 'principles based' features, consolidated reporting, 'fair value' measurement, increased pressure for non-financial disclosures have resulted in brief and various disclosure practices regarding the main body of each statements and vast amount of note description requirements. Meanwhile, a host of previous studies on IFRS disclosures have incorporated regulatory and/or 'compete information' perspectives, mainly focusing on suggesting further enforcement of strengthened requirements and providing guidelines for specific treatments. Thus, as an extension of prior findings and suggestions this study had explored to conduct an integrative approach embracing views of the reporting entities and the users of financial information. In spite of all the state-driven efforts for faithful representation and comparability of corporate financial reports, an overhaul of disclosure practices of fiscal year 2010 and 2011 had revealed numerous cases of insufficiency and discordance in terms of mandatory norms and market expectations. As to the causes of such shortcomings, this study identified several factors from the corporate side and the users of the information; some inherent aspects of IFRS, industry/corporate-specific context, expenditures related to internalizing IFRS system, reduced time frame for presentation. lack of clarity and details to meet the quality of information - understandability, comparability etc. - commonly requested by the user group. In order to improve current disclosure practices, dual approach had been suggested; Firstly, to encourage and facilitate implementation, (1) further segmentation and differentiation of mandates among companies, (2) redefining the scope and depth of note descriptions, (3) diversification and coordination of reporting periods, (4) providing support for equipping disclosure systems and granting incentives for best practices had been discussed. Secondly, as for the hard measures, (5) regularizing active involvement of corporate and user group delegations in the establishment and amendment process of K-IFRS (6) enforcing detailed and standardized disclosure on reporting entities had been recommended.

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