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Utility of B-type Natriuretic Peptide in Patients with Acute Respiratory Distress Syndrome (급성호흡곤란증후군 환자에 있어서 B-type Natriuretic Peptide의 유용성)

  • Rhee, Chin Kook;Joo, Young Bin;Kim, Seok Chan;Park, Sung Hak;Lee, Sook Young;Koh, Yoon Seok;Kim, Young Kyoon
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.5
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    • pp.389-397
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    • 2007
  • Background B-type natriuretic peptide (BNP) has been shown to be strong mortality predictors in a wide variety of cardiovascular syndromes. Little is known about BNP in patients with acute respiratory distress syndrome (ARDS). We studied whether BNP can predict mortality in patients with ARDS. Method Echocardiographic study was done to all patients with ARDS, and we excluded patient with low ejection fraction (less than 50%) or showing any features of diastolic dysfunction. 47 patients were enrolled between December, 2003 and February, 2006. Parameters including BNP were obtained within 24h hours at the time of enrollment. Result Mean BNP concentrations and APACHE II scores differed between the survivors and nonsurvivors (BNP, $219.5{\pm}57.7pg/mL$ vs $492.3{\pm}88.8pg/mL$; p=0.013, APACHE II score, $17.4{\pm}1.6$ vs $23.1{\pm}1.3$, p=0.009, respectively). With the use of the threshold value for BNP of 585 pg/mL, the specificity for the prediction of mortality was 94%. The threshold value for APACHE II of 15.5 showed sensitivity of 87%. 'APACHE II + $11{\times}logBNP$' showed sensitivity 63%, and specificity 82%, using threshold value for 46.14. Conclusion BNP concentrations and APCHE II scores were more elevated in nonsurvivors than survivors in patients with ARDS who have normal ejection fraction. BNP can predict mortality. Further study should be done.

Characteristics of Membrane Permeability on the Separation of Solid in a Liquid Livestock Manure (축분액비의 고액분리에 있어서 분리막의 투과특성)

  • 황명구;차기철;이명규
    • Journal of Animal Environmental Science
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    • v.6 no.3
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    • pp.175-184
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    • 2000
  • A lab-scale MF membrane reactor was installed to investigate the membrane permeability, characteristics of membrane fouling at each conditions, and quality of permeate (liquid livestock manure) in the separation of solid-matters using membrane. Experiment was divided three filtration type such as follows; continuous filtration, gravity filtration, and intermittent filtration. As a result of experiment, flux 1 LMH was maintained for 7days, and trans-membrane pressure(TMP) was increased gradually under 10cmHg, but it was increased immediately after 10cmHg, respectively. However, the flux was increased, the Tmax was decreased exponential more and more. During the pure-flux test, most of the fouling of membrane was reversible. At the gravity filtration, permeate could be obtained as 1.75 LMH for 3.5days without any other electronic pressure. As an investigation of membrane surface, this study could be decided that the reason of fouling at the lower flux (Run 1 and 2) was attached matters in membrane surface, but at the higher flux (Run 4-6) was concentration polarization.

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A Study on Shaker's Free Design from Fashion (유행(流行)으로부터 자유로운 세이커(Shaker) 디자인에 대한 고찰)

  • Choi, Sung-Woon;Huh, Jin
    • Archives of design research
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    • v.20 no.3 s.71
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    • pp.279-288
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    • 2007
  • Today, design is not free from fashion, which emerges and vanishes temporarily, and aims at equalization. As a result, products quickly become obsolete because of fashion. This means that the span of products is determined by a social concept, which is not clarified, regardless of their functions. Usable products will gradually disappear from us and it will cause serious environmental problems, unless we can find out measures against fashion. As such, it is important to study the characteristics of the shaker's design in this circumstance. The Shaker's community has a distinguishable difference from other general societies. Temporary fashion and misled information cannot interfere with their consciousness. Religion, the life and the principle of design have developed on the same level in their community. Especially, any decoration or the difference of materials is not allowed in shaker's design. It reflects their thinking that all people are equal in the sight of God. Therefore, any decoration for social and economical superiority can not be used. Through this consciousness, they can be free from fashion or decoration. They, also, believe that they can reach perfection through practicality and simplicity. The reason why shaker's design is not disturbed by fashion is that their belief is involved in their design. Consequently, if religious or conscious contents are primarily set up, design can be free from fashion and products can be used for a long time.

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Fog Detection over the Korean Peninsula Derived from Satellite Observations of Polar-orbit (MODIS) and Geostationary (GOES-9) (극궤도(MODIS) 및 정지궤도(GOES-9) 위성 관측을 이용한 한반도에서의 안개 탐지)

  • Yoo, Jung-Moon;Yun, Mi-Young;Jeong, Myeong-Jae;Ahn, Myoung-Hwan
    • Journal of the Korean earth science society
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    • v.27 no.4
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    • pp.450-463
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    • 2006
  • Seasonal threshold values for fog detection over the ten airport areas within the Korean Peninsula have been derived from the data of polar-orbit Aqua/Terra MODIS and geostationary GOES-9 during a two years. The values are obtained from reflectance at $0.65{\mu}m\;(R_{0.65})$ and the difference in brightness temperature between $3.7{\mu}m\;and\;11{\mu}m\;(T_{3.7-11})$. In order to examine the discrepancy between the threshold values of two kinds of satellites, the following four parameters have been analyzed under the condition of daytime/nighttime and fog/clear-sky, utilizing their simultaneous observations over the Seoul metropolitan area: brightness temperature at $3.7{\mu}m$, the temperature at $11{\mu}m,\;the\;T_{3.7-11}$ for day and night, and the $R_{0.65}$ for daytime. The parameters show significant correlations (r<0.5) in spatial distribution between the two kinds of satellites. The discrepancy between their infrared thresholds is mainly due to the disagreement in their spatial resolutions and spectral bands, particularly at $3.7{\mu}m$. Fog detection from GOES-9 over the nine airport areas except the Cheongju airport has revealed accuracy of 60% in the daytime and 70% in the nighttime, based on statistical verification. The accuracy decreases in foggy cases with twilight, precipitation, short persistence, or the higher cloud above fog. The sensitivity of radiance and reflectance with wavelength has been analyzed in numerical experiments with respect to various meteorological conditions to investigate optical characteristics of the three channels.

Fatty Acid Composition and Oxidative Stability of Citron Seed Oils (유자 종실유의 지방산 조성 및 산화안정성)

  • Lee Soo-Jung;Choi Sun-Young;Shin Jung-Hye;Kim Sung-Hyun;Lim Hyun-Cheol;Sung Nak-Ju
    • Journal of Life Science
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    • v.16 no.3 s.76
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    • pp.427-432
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    • 2006
  • The possibility of citron seed oil for use as food resources of fats was tested by analyzing the composition of fatty acid and oxidative stability. Oil yield from citron seed was 55.4% in without roasting and 56.8% with roasting. Total mineral content in citron seed without and with roasting were 2,820.33 mg/kg, 1,702.55 mg/kg, respectively. For all citron seed oils tested, the potassium content was found to be the highest among four kinds of minerals detected in this study. Further, major fatty acids detected in the citron seed oils were linoleic acid, oleic acid and palmitic acid. Their relative contents with respect to total fatty acid contents were 77.12% in without roasting and 67.67% in with roasting. This result indicated that roasting the citron seed decreased the acid contents. However, POV (peroxide value) and acid value of citron seed oils were in,.eased significantly with increasing the storage days and heating time. In details, POV was $84.17{\pm}1.68meq/kg$ in without roasting and $76.46{\pm}1.19meq/kg$ with roasting, after 28 days. Acid value was $9.52{\pm}0.27mg\;KOH/g,\;8.35{\pm}0.09mg\;KOH/g$, respectively, After the 48 hours heating at $180^{\circ}C$, POV of citron seed oils was increased by 3.8 times, irrespective of roasting. Yet, acid value increased dramatically 8.3 in without and 6.4 times with roasting, exhibiting its dependence on roasting. During storage time, oxidative stability of citron seed oils was higher than heating.

Voluntary Motor Control Change after Gait Training in Patients with Spinal Cord Injury (척수신경손상 환자의 보행훈련 전.후의 능동적 근육제어의 변화)

  • 임현균;이동철;이영신;셔우드아더
    • Journal of Biomedical Engineering Research
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    • v.24 no.2
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    • pp.133-140
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    • 2003
  • In this study, muscle activity was measured using surface EMG (sEMG) during a voluntary maneuver (ankle dorsiflexion) in the supine position was compared pre and post gait training. Nine patients with incomplete spinal cord injury participated in a supported treadmill ambulation training (STAT), twenty minutes a day, five days a week for three months. Two tests, a gait speed test and a voluntary maneuver test, were made the same day, or at least the same week, pre and post gait training. Ten healthy subjects' data recorded using the same voluntary maneuvers were used for the reference. sEMG measured from ten lower limb muscles was used to observe the two features of amplitude and motor control distribution pattern, named response vector. The result showed that the average gait speed of patients increased significantly (p〈0.1) from 0.47$\pm$0.35 m/s to 0.68$\pm$0.52 m/s. In sEMG analysis, six out of nine patients showed a tendency to increase the right tibialis anterior activity during right ankle dorsiflexion from 109.7$\pm$148.5 $mutextrm{V}$ to 145.9$\pm$180.7 $mutextrm{V}$ but it was not significant (p〈0.055). In addition, only two patients showed increase of correlation coefficient and total muscle activity in the left fide during left dorsiflexion. Patients' muscle activity changes after gait training varied individually and generally depended on their muscle control abilities of the pre-STAT status. Response vector being introduced for quantitative analysis showed good Possibility to anticipate. evaluate, and/or guide patients with SCI, before and after gait training.

Evaluation of Characteristics of Re-liquefaction Resistance in Saturated Sand Deposits Using 1-g Shaking Table Test (1-g 진동대시험을 이용한 포화된 모래지반의 재액상화 강도 특성 평가)

  • Ha Ik-Soo;Kim Myoung-Mo
    • Journal of the Korean Geotechnical Society
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    • v.21 no.4
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    • pp.65-70
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    • 2005
  • Many case histories of re-liquefaction phenomena seem to support the idea that sand deposits, if they once have been liquefied, could be reliquefied again by a subsequent earthquake even though the earthquake is smaller than the previous one. The magnitude of the strains induced in the initial liquefaction has a significant influence on the resistance of the sample to re-liquefaction. The deposits undergoing liquefaction experience large shear strain during liquefaction. And this previous strain changes the microstructure into highly anisotropic structure such as columnlike structure and connected voids. This type of anisotropy is so unstable that it can reduce re-liquefaction resistance. It is blown that the extent of anisotropic structural change depends on the gradation characteristics of ground. The purpose of this study is to estimate the correlation between the gradation characteristics of the sand and the ratio of re-liquefaction resistance to liquefaction resistance. In this study, 1-g shaking table tests were carried out on five different kinds of sands. During the tests the values of excess pore pressure at various depths and surface settlements were measured. Re-liquefaction resistances were not affected by the initial void ratio and the effective confining pressures, and the deposits of all test sands which had once been liquefied were reliquefied in the cyclic loading number below 1 to 1.5. The ratio of re-liquefaction resistance to liquefaction resistance linearly decreased as $D_{10}/C_u$ increased, and was constant as about 0.2 above the value of $D_{10}/C_u$, 0.15 mm.

An Analysis on Characteristics of Turbulence Energy Dissipation Rate from Comparison of Wind Profiler and Rawinsonde (연직바람관측장비와 레윈존데의 비교를 통한 난류 에너지 감소률의 특성 분석)

  • Kang, Woo Kyeong;Moon, Yun Seob;Jung, Ok Jin
    • Journal of the Korean earth science society
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    • v.37 no.7
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    • pp.448-464
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    • 2016
  • The purpose of this study is to optimize the parameters related to consensus coherency within the PCL 1300, the operating program of wind profiler, from a validation of wind data between rawinsonde and wind profiler at Chupungryeong ($36^{\circ}13^{\prime}$, $127^{\circ}59^{\prime}$) site in Korea. It is then to analyze the diurnal and seasonal characteristics of the turbulence energy dissipation rate (${\varepsilon}$) in clear and rainy days from March 2009 to February 2010. In comparison of the wind data between wind profiler and rawinsonde during April 22-23, 2010, it was shown in a big error more than $10ms^{-1}$ over the height of 3,000 meters in the zonal (u) and meridional (v) wind components. When removing more than $10ms^{-1}$ in each wind speed difference of u an v components between the two instruments, the correlation coefficients of these wind components were 0.92 and 0.88, respectively, and the root mean square errors were 3.07 and $1.06ms^{-1}$. Based on these results, when the data processing time and the minimum available data within the PCL 1300 program were adjusted as 30 minutes and 60%, respectively, the bias errors were small. In addition, as a result of an analysis of sensitivity to consensus coherency of u and v components within the PCL1300 program, u components were underestimated in radial coherency, instantaneous and winbarbs coherency, whereas v components were overestimated. Finally by optimizing parameters of the PCL1300 program, the diurnal and seasonal means of ${\varepsilon}$ at each height were higher in rainy days than those in clear days because of increasing in the vertical wind speed due to upward and downward motions. The mean ${\varepsilon}$ for clear and rainy days in winter was lower than those of other seasons, due to stronger horizontal wind speed in winter than those in other seasons. Consequently, when the turbulence energy dissipation rates in the vertical wind speed of more than ${\pm}10cm\;s^{-1}$ were excluded for clear and rainy days, the mean ${\varepsilon}$ in rainy days was 6-7 times higher than that in clear days, but when considering them, it was 4-5 times higher.

Changes in Plasma and Urine Endothelin Levels During Acute Exacerbation of Asthma (급성 천식발작시 혈장 및 요중 Endothelin 농도 변동)

  • Chang, Jung-Hyun;Shin, Tae-Rim;Woo, Ga-Eun;Kim, Jong-Seon;Hong, Eun-Soon;Seo, Gi-Yeoul;Cha, Joo-Hyun;Kim, Mi-Seon;Kim, Yeung-Seon;Cho, Young-Joo
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.4
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    • pp.844-852
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    • 1997
  • Background : Recent studies have documented increased release of endothelin(ET) during acute attack of asthma. The purpose of this study is to observe the link between plasma level and urinary excretion of each and changes during acute exacerbation. Method : Plasma and 24 hour urine were collected from sixteen asthmatics during acute exacerbation, twice ; first day of symptomatic exacerbation and two weeks after treatment. Controls were ten healthy normal subjects. All patients were treated with corticosteroid and beta-2 adrenergic agonist on admission. ET was determined by radioimmmunoassay and had 100% cross reactivity with ET-1, 67% with ET-2, 84% with ET-3, and 8% with Big-ET. Results : Plasma ETs were significantly elevated during acute attack of asthma compared with those in remission and controls.,However, there was no significant changes in urine ET concentrations or total ET amounts in 24 hour urine during exacerbation upto two weeks. Those levels of urine ET in asthmatics were still higher than controls. ET concentrations in plasma or urine were not correlated with pulmonary functional parameters and hypoxemia. Conclusion : The findings suggests that increased plasma ETs are related with exaggerated release during acute asthma. Urinary ET excretion is increased in asthma. However, urine ET changes during exacerbation should be observed in a larger and longer scale.

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The Effects of Personal, Familial, School Environmental Variables on Mobile Phone Addiction by Adolescent (청소년의 휴대폰 중독성에 영향을 미치는 개인, 가족, 학교환경 변인)

  • Lee, Yeon-Mi;Lee, Seon-Jeong;Shin, Hyo-Shick
    • Journal of Korean Home Economics Education Association
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    • v.21 no.3
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    • pp.29-43
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    • 2009
  • The purposes of this study were to examine effective variables influencing on adolescents' mobile phone addiction. The subjects were the 666 middle or high school students who had their own mobile phone in Gwangju. Data were analyzed with frequency, percentage, cronbach's ${\alpha}$, mean, SD, pearson's correlation and multiple regression using SPSS/PC WIN 14.0 program. The major findings were as follows: 1. The most frequently used function of student mobile phones was text message and they used text message more than 41 times a day. Mostly they were talking to the same sex friends on the phone and the monthly charges ranged from 20,000 to 30,000 won. In general, they called to their friends after school. Their parents' attitudes toward their mobile phone using showed that the most of their parents did not care about their children's mobile phone use. The restriction of using their mobile phone at school was normal. 2. The average scores of mobile phone addiction were lower than median(3.0) and self esteem, self control, family strengths, peer conformity and school life adaptation were higher than median. 3. The adolescence's mobile phone additions were influenced by peer conformity, school life adaptation, school levels, sex and self control. And these variables explained to the adolescence's mobile phone additions about 28%.

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