• Feed Journal
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• v.4 no.8 s.36
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• pp.114-118
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• 2006

살모넬라 갈리나륨(Salmonella gallinarum)이 원인체인 가금티프스는 모든 품종의 닭에서는 물론이고 어린 일령의 병아리에서부터 산란중인 성계에 이르기까지 전 일령의 닭에서 높은 폐사를 일으키는 세균성 질병으로 우리나라뿐만 아니라 세계적으로 발생되고 있는 질병이다.

• Korean Journal of Poultry Science
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• v.44 no.3
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• pp.181-188
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• 2017

Bacteriophages are viruses that exclusively infect bacterial cells, and lytic bacteriophages can be used as a safe alternative to antibiotics for the prevention and treatment of animal diseases. In this study, we attempted to isolate and characterize bacteriophages for Salmonella enterica serovar Gallinarum (Salmonella Gallinarum), the causative agent of fowl typhoid in chickens. Ten bacteriophages were isolated from samples of sewage from seven poultry slaughterhouses. One of these isolate, designated as $SG{\Phi}-YS$ SP and classified in the family Myoviridae, produced plaques with seven Salmonella Gallinarum strains. However, no plaques were produced with any of the Salmonella enterica serovar Enteritidis strains tested, suggesting that this bacteriophage is Salmonella Gallinarum specific. To assess the lytic ability of $SG{\Phi}-YS$ SP against Salmonella Gallinarum, bacterial growth rates following inoculation of the bacteriophage were compared with the control. The $SG{\Phi}-YS$ SP treatment, with a multiplicity of infection of 10, reduced the growth of Salmonella Gallinarum by 2.21 log cfu/mL at 6 h, and 2.13 log cfu/mL at 9 h, suggesting that this bacteriophage isolate could be used for the prevention or treatment of Salmonella Gallinarum infection in chickens.