• Title/Summary/Keyword: 산화방지

Search Result 759, Processing Time 0.035 seconds

Protective Effect of Angelica keiskei Juice and Oenanthe javanica DC Juice on Oxidative Stress (산화 스트레스에 대한 신선초 녹즙과 돌미나리 녹즙의 보호효과)

  • Lee, Doo-Jin;Lee, Jin-Ha;Lee, Ok-Hwan;Kim, Boh-Kyung;Park, Kun-Young;Kim, Jong-Dai
    • Korean Journal of Food Science and Technology
    • /
    • v.47 no.4
    • /
    • pp.517-524
    • /
    • 2015
  • The objectives of the present study were to investigate the protective effects of Angelica keiskei juice and Oenanthe javanica juice against oxidative damage in LLC-$PK_1$ renal epithelial cells and to evaluate their free radical-scavenging activities. Both A. keiskei juice and O. javanica juice showed a strong in vitro antioxidant activities such as ${\alpha}$, ${\alpha}$-diphenyl-${\beta}$-picrylhydrazyl (DPPH), nitric oxide (NO), $O_2{^-}$, and ${\cdot}OH$ radical-scavenging activities. The LLC-$PK_1$ cells showed significant lipid peroxidation and cell death due to oxidative stress when it was induced by 2, 2'-azobis (2-amidinopropane) dihydrochloride (AAPH), sodium nitroprusside (SNP), pyrogallol, and 3-morpholinosydnonimine (SIN-1). Treatment with both A. keiskei juice and O. javanica juice significantly increased cell viability and inhibited lipid peroxidation. These results suggest that A. keiskei juice and O. javanica juice are potential natural antioxidants.

Effect of Trifunctional Monomers and Antioxidants on the Crosslinking Reaction of Polyethylene (폴리에틸렌의 가교반응에 미치는 삼관능성 단위체와 산화장지제의 영향)

  • Hyung Chick Pyun;Young Chul Lee;Kil Jeong Kim;Byung Mok Yoon
    • Nuclear Engineering and Technology
    • /
    • v.14 no.2
    • /
    • pp.70-77
    • /
    • 1982
  • The crosslinking reaction and oxidative stability of low-density polyethylene were studied in the presence of trifunctional monomers and antioxidants with electron beam. The trifunctional monomers used in this study are Trimethylolpropane triacrylate(TMPTA), Trimethylolpropane trimethacrylate(TMPTM) and Triallyl cyanurate(TAC). And the antioxidants are Irganox 1010 (Pentaerythritoltetrakis[3-(3,5-di-t-butyl-4-hydroxyphenyl)-propionatel]), Santo-nox R(4,4'-Thio-bis(3-methyl-6-t-butylphenol)), Nocrac D(N-phenyl-$\beta$-naphthylamine) and Bis-phenol A(4,4'-Isopropylidene bisphenol). Among the monomers, TMPTA is the best crosslinking agent and prvides polyethylene with oxidative stability. Among the antioxidants, Nocrac D is the best antioxidant for polyethylene.

  • PDF

Antioxidant and cytotoxic activities of curcumin and its analogs: An exploration of structure-activity relationships (Curcumin과 관련 성분들의 산화방지활성과 세포독성 분석 및 구조와 활성 연관성 조사)

  • Lee, Bo-Hyun;Kim, Hee Jeong;Hong, Jungil
    • Korean Journal of Food Science and Technology
    • /
    • v.53 no.4
    • /
    • pp.463-469
    • /
    • 2021
  • Bioactivities of curcumin, a major pigment of Curcuma longa L., have been widely investigated. In this study, the antioxidant and cytotoxic properties of curcumin and its analogs including ferulic acid, dibenzoylmethane (DBM), and tetrahydrocurcumin (THC), and their structure-activity relationships were assessed. Ferulic acid, THC, and curcumin showed strong scavenging activities against several radicals and exhibited considerable lipid peroxidation inhibitory activity. Curcumin showed the strongest cytotoxic activities against HeLa, HCT-116, IEC-6 and INT 407 cells, whereas ferulic acid did not show any cytotoxic effect up to 100 µM against these cell lines. Cytotoxicity of curcumin and THC was significantly enhanced by superoxide dismutase and diminished by N-acetylcysteine. The combination treatment of curcumin and ferulic acid enhanced the cytotoxicity, whereas the combination of curcumin and DBM offset their toxicity. These results suggest that methoxy phenolic and β-diketon moieties are crucial for the antioxidant- and cytototoxic activities of curcumin, respectively.

Antioxidant, antibacterial, antifungal, and anti-inflammatory effects of 15 tree essential oils (수목 방향유 15종의 산화방지, 항세균, 항진균 및 항염증 효과)

  • Jo, Se Jin;Park, Mi-Jin;Guo, Rui Hong;Park, Jung Up;Yang, Ji Yoon;Kim, Jae-Woo;Lee, Sung-Suk;Kim, Young Ran
    • Korean Journal of Food Science and Technology
    • /
    • v.50 no.5
    • /
    • pp.535-542
    • /
    • 2018
  • The current study investigated the beneficial effects of 15 essential oils isolated from tree branches, leaves, and flowers. Among these oils, clove bud and Illicium anisatum oils showed the most potent anti-oxidant effects on 1,1-diphenyl-2-picrylhydrazyl and 2,2'azinbis-(3-ethyl-benzothiazoline-6-sulfonic acid) radical scavenging activities. Next, we evaluated the antibacterial effects of 15 essential oils on Staphylococcus aureus, Listeria monocytogenes, Escherichia coli O157:H7, Salmonella typhimurium, and Streptococcus mutans. Clove bud significantly decreased growth of 5 bacterial strains. In addition, clove bud, Magnolia kobus, Picea abies and Chamaecyparis obtuse significantly reduced growth of the fungi, Aspergillus fumigatus, Aspergillus ochraceus, Candida albicans and Trichophyton rubrum. Additionally, clove bud also remarkably reduced the expression of cyclooxygenase-2 and inducible NO synthase in lipopolysaccharide-activated RAW264.7 cells. These results indicate that essential oils isolated from trees, which exhibit antioxidant, antibacterial, antifungal and anti-inflammatory properties, may be potentially useful in the development of cosmetic ingredients.

Antioxidative Effect of Ascorbic Acid Solubilized via Reversed Micelle in Perilla Oil (역미설계를 이용한 들깨기름의 산화안정성 향상에 관한 연구)

  • Yi, Ock-Sook;Shin, Hyun-Kyung
    • Korean Journal of Food Science and Technology
    • /
    • v.21 no.5
    • /
    • pp.706-709
    • /
    • 1989
  • Ascorbic acid was solubilized in perilla oil via reversed micelle using small amount of water and lecithin as surfactant. The effect of the solubilized ascorbic acid on the oxidative stability of perilla oil was investigated. The autoxidation of the oil was greatly retarded with the solubilized ascorbic acid compared to the synthetic antioxidants employed. However, the combination with ${\delta}-tocopherol$ did not show any significant synergism.

  • PDF

Characteristics of Photostabilizers in Photochromic Formulations

  • Sin, Jong-Il;Sin, Seung-Rim;Park, Su-Yeol;Kim, Si-Seok;Lee, In-Ja;An, Gyeong-Ryong;Lee, Sang-O;Yun, Hye-Su;Jeon, Geun-HanGuk
    • Proceedings of the Korean Society of Dyers and Finishers Conference
    • /
    • 2009.11a
    • /
    • pp.117-118
    • /
    • 2009
  • Photochromic dye의 광안정성을 향상시키기 위해 다양한 형태의 산화방지제 및 자외선흡수제를 사용하고 있다. PMMA를 MEK에 녹이고 photochromic dye, 다양한 형태의 산화방지제 및 자외선흡수제를 첨가하여 film 조성액을 만들고 PET film에 coating하여 도막을 만들어 광변색소의 안정성을 관찰하였다. 산화방지제 및 자외선 흡수제의 종류에 따른 광변색소의 변색특성을 관찰하였으며, 농도에 따른 광변색소의 광안정성을 관찰하였다.

  • PDF